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Search results 801 to 809 out of 809 for Bambi

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0.017s

Type

Details

Score

Strain

MGI:6428217 | C57BL/6JSmoc-Bambi<em1Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

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Publication

25428821 | J:223872

First Author:	Candini O
Year:	2015
Journal:	Stem Cells
Title:	Mesenchymal progenitors aging highlights a miR-196 switch targeting HOXB7 as master regulator of proliferation and osteogenesis.
Volume:	33
Issue:	3
Pages:	939-50

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Protein Domain

IPR045806 | BAMBI_C

Type:

Domain

Description:

This entry represents the C-terminal domain of BAMBI proteins. It contains the transmembrane domain and a short intracellular domain that, unlike all other known TGF-beta type I or type II receptors, does not encode a serine/threonine-kinase domain. However, it shares sequence homology with the E6 and catalytic loops of receptor serine/threonine kinases []. This entry consists of several eukaryotic BMP and activin membrane-bound inhibitor (BAMBI) proteins. Members of the transforming growth factor-beta (TGF-beta) superfamily, including TGF-beta, bone morphogenetic proteins (BMPs), activins and nodals, are vital for regulating growth and differentiation. BAMBI is related to TGF-beta-family type I receptors but lacks an intracellular kinase domain [].BAMBI is an essential regulator of cell proliferation and differentiation that represses TGF-beta and enhances Wnt/beta-catenin signalling in various cell types [, ]. Thus, it is involved in a high number of physiological and pathological processes [, , ]. It stably associates with TGF-beta-family receptors and inhibits BMP and activin as well as TGF-beta signalling [].

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Protein Domain

IPR045807 | BAMBI_N

Type:

Domain

Description:

This entry represents the N-terminal domain of the BAMBI proteins. This domain might contain putative extracellular domains [].This entry consists of several eukaryotic BMP and activin membrane-bound inhibitor (BAMBI) proteins. Members of the transforming growth factor-beta (TGF-beta) superfamily, including TGF-beta, bone morphogenetic proteins (BMPs), activins and nodals, are vital for regulating growth and differentiation. BAMBI is related to TGF-beta-family type I receptors but lacks an intracellular kinase domain [].BAMBI is an essential regulator of cell proliferation and differentiation that represses TGF-beta and enhances Wnt/beta-catenin signalling in various cell types [, ]. Thus, it is involved in a high number of physiological and pathological processes [, , ]. It stably associates with TGF-beta-family receptors and inhibits BMP and activin as well as TGF-beta signalling [].

•

Publication

22187378 | J:191512

First Author:	Luo X
Year:	2012
Journal:	Diabetes
Title:	Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors.
Volume:	61
Issue:	1
Pages:	124-36

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Publication

24657401 | J:279220

First Author:	Tomita K
Year:	2014
Journal:	J Hepatol
Title:	Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells.
Volume:	61
Issue:	1
Pages:	98-106

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Publication

27006448 | J:239491

First Author:	Kim YH
Year:	2016
Journal:	FASEB J
Title:	Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesis.
Volume:	30
Issue:	7
Pages:	2528-40

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Publication

32209358 | J:299643

First Author:	Zeigler AC
Year:	2020
Journal:	Matrix Biol
Title:	Computational model predicts paracrine and intracellular drivers of fibroblast phenotype after myocardial infarction.
Volume:	91-92

Pages:	136-151

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Publication

22505317 | J:317499

First Author:	Studach LL
Year:	2012
Journal:	Hepatology
Title:	Subset of Suz12/PRC2 target genes is activated during hepatitis B virus replication and liver carcinogenesis associated with HBV X protein.
Volume:	56
Issue:	4
Pages:	1240-51

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