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Search results 101 to 200 out of 300 for Tlr6

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Type Details Score
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334823
Age: postnatal day 12
Image: 1
Specimen Label: P12
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:7334814
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334823
Age: postnatal month 5
Image: 1
Specimen Label: P5m
Detected: true
Specimen Num: 12
Publication
First Author: DePaolo RW
Year: 2012
Journal: J Exp Med
Title: A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.
Volume: 209
Issue: 8
Pages: 1437-44
Publication
First Author: Grote K
Year: 2010
Journal: Blood
Title: Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration.
Volume: 115
Issue: 12
Pages: 2543-52
Publication
First Author: Sanchez-Lopez JA
Year: 2014
Journal: Biol Reprod
Title: Local activation of uterine Toll-like receptor 2 and 2/6 decreases embryo implantation and affects uterine receptivity in mice.
Volume: 90
Issue: 4
Pages: 87
Publication
First Author: Shen KY
Year: 2014
Journal: J Immunol
Title: Molecular mechanisms of TLR2-mediated antigen cross-presentation in dendritic cells.
Volume: 192
Issue: 9
Pages: 4233-41
Publication
First Author: Kurt-Jones EA
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis.
Volume: 101
Issue: 5
Pages: 1315-20
Publication
First Author: Pasquevich KA
Year: 2010
Journal: J Immunol
Title: The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis.
Volume: 184
Issue: 9
Pages: 5200-12
Publication
First Author: Deckwerth TL
Year: 1998
Journal: Exp Neurol
Title: Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation.
Volume: 152
Issue: 1
Pages: 150-62
Publication
First Author: De Luca A
Year: 2012
Journal: J Clin Invest
Title: CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease.
Volume: 122
Issue: 5
Pages: 1816-31
Publication
First Author: Buwitt-Beckmann U
Year: 2006
Journal: J Biol Chem
Title: TLR1- and TLR6-independent recognition of bacterial lipopeptides.
Volume: 281
Issue: 14
Pages: 9049-57
Publication
First Author: Jimenez-Dalmaroni MJ
Year: 2009
Journal: PLoS One
Title: Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.
Volume: 4
Issue: 10
Pages: e7411
Publication
First Author: Yang D
Year: 2008
Journal: J Exp Med
Title: Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.
Volume: 205
Issue: 1
Pages: 79-90
Publication
First Author: Marta M
Year: 2008
Journal: Eur J Immunol
Title: Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis.
Volume: 38
Issue: 2
Pages: 565-75
Publication
First Author: Turner JD
Year: 2009
Journal: J Biol Chem
Title: Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.
Volume: 284
Issue: 33
Pages: 22364-78
Publication
First Author: Katz J
Year: 2006
Journal: Infect Immun
Title: Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS.
Volume: 74
Issue: 5
Pages: 2809-16
Publication
First Author: Sheedy FJ
Year: 2013
Journal: Nat Immunol
Title: CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Volume: 14
Issue: 8
Pages: 812-20
Publication
First Author: Panigrahi S
Year: 2013
Journal: Circ Res
Title: Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis.
Volume: 112
Issue: 1
Pages: 103-12
Publication
First Author: Adachi K
Year: 2001
Journal: J Immunol
Title: Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism.
Volume: 167
Issue: 10
Pages: 5928-34
Publication
First Author: Cadman ET
Year: 2008
Journal: Infect Immun
Title: Alterations of splenic architecture in malaria are induced independently of Toll-like receptors 2, 4, and 9 or MyD88 and may affect antibody affinity.
Volume: 76
Issue: 9
Pages: 3924-31
Publication
First Author: Klekotka PA
Year: 2010
Journal: J Invest Dermatol
Title: Contrasting roles of the IL-1 and IL-18 receptors in MyD88-dependent contact hypersensitivity.
Volume: 130
Issue: 1
Pages: 184-91
Publication
First Author: Zeisel MB
Year: 2005
Journal: J Immunol
Title: Cross talk between MyD88 and focal adhesion kinase pathways.
Volume: 174
Issue: 11
Pages: 7393-7
Publication
First Author: Duggan JM
Year: 2011
Journal: J Immunol
Title: Synergistic interactions of TLR2/6 and TLR9 induce a high level of resistance to lung infection in mice.
Volume: 186
Issue: 10
Pages: 5916-26
Publication  
First Author: Monlish DA
Year: 2020
Journal: Exp Hematol
Title: TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS.
Volume: 88
Pages: 42-55
Publication
First Author: Gaddis DE
Year: 2013
Journal: J Leukoc Biol
Title: Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis.
Volume: 93
Issue: 1
Pages: 21-31
Publication
First Author: Speer T
Year: 2013
Journal: Immunity
Title: Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.
Volume: 38
Issue: 4
Pages: 754-68
Publication
First Author: Stewart CR
Year: 2010
Journal: Nat Immunol
Title: CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
Volume: 11
Issue: 2
Pages: 155-61
Publication
First Author: Rothfuchs AG
Year: 2004
Journal: J Immunol
Title: Intracellular bacterial infection-induced IFN-gamma is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-alpha beta-STAT1 signaling.
Volume: 172
Issue: 10
Pages: 6345-53
Publication
First Author: Biswas S
Year: 2016
Journal: Blood
Title: Novel phosphatidylethanolamine derivatives accumulate in circulation in hyperlipidemic ApoE-/- mice and activate platelets via TLR2.
Volume: 127
Issue: 21
Pages: 2618-29
Publication
First Author: Medina EA
Year: 2010
Journal: J Immunol
Title: Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain.
Volume: 185
Issue: 12
Pages: 7562-72
Publication
First Author: Okun E
Year: 2010
Journal: J Neurochem
Title: TLR2 activation inhibits embryonic neural progenitor cell proliferation.
Volume: 114
Issue: 2
Pages: 462-74
Publication
First Author: Borgel J
Year: 2010
Journal: Nat Genet
Title: Targets and dynamics of promoter DNA methylation during early mouse development.
Volume: 42
Issue: 12
Pages: 1093-100
Publication
First Author: Enoksson M
Year: 2011
Journal: J Immunol
Title: Mast cells as sensors of cell injury through IL-33 recognition.
Volume: 186
Issue: 4
Pages: 2523-8
Publication
First Author: Togbe D
Year: 2007
Journal: Am J Pathol
Title: Murine cerebral malaria development is independent of toll-like receptor signaling.
Volume: 170
Issue: 5
Pages: 1640-8
Publication
First Author: Chen CJ
Year: 2007
Journal: Nat Med
Title: Identification of a key pathway required for the sterile inflammatory response triggered by dying cells.
Volume: 13
Issue: 7
Pages: 851-6
Publication
First Author: Kumar H
Year: 2009
Journal: Biochem J
Title: Pathogen recognition in the innate immune response.
Volume: 420
Issue: 1
Pages: 1-16
Publication
First Author: Tang H
Year: 2010
Journal: Nat Immunol
Title: The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.
Volume: 11
Issue: 7
Pages: 608-17
Publication
First Author: Hoebe K
Year: 2003
Journal: J Endotoxin Res
Title: Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening.
Volume: 9
Issue: 4
Pages: 250-5
Publication
First Author: Wang Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Volume: 113
Issue: 7
Pages: E884-93
Publication
First Author: Ip WK
Year: 2008
Journal: J Exp Med
Title: Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome.
Volume: 205
Issue: 1
Pages: 169-81
Publication
First Author: Pimentel-Coelho PM
Year: 2013
Journal: J Neurosci
Title: Evidence for a gender-specific protective role of innate immune receptors in a model of perinatal brain injury.
Volume: 33
Issue: 28
Pages: 11556-72
Publication
First Author: Alugupalli KR
Year: 2007
Journal: J Immunol
Title: MyD88- and Bruton's tyrosine kinase-mediated signals are essential for T cell-independent pathogen-specific IgM responses.
Volume: 178
Issue: 6
Pages: 3740-9
Publication  
First Author: Gao Y
Year: 2021
Journal: Int J Mol Sci
Title: YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes.
Volume: 22
Issue: 13
Publication
First Author: Chen CJ
Year: 2006
Journal: J Clin Invest
Title: MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals.
Volume: 116
Issue: 8
Pages: 2262-71
Publication
First Author: Cook MC
Year: 2006
Journal: Curr Opin Immunol
Title: ENU-mutagenesis: insight into immune function and pathology.
Volume: 18
Issue: 5
Pages: 627-33
Publication
First Author: Balounová J
Year: 2019
Journal: Nat Commun
Title: Toll-like receptor 2 expression on c-kit+ cells tracks the emergence of embryonic definitive hematopoietic progenitors.
Volume: 10
Issue: 1
Pages: 5176
Publication
First Author: Kaul D
Year: 2012
Journal: PLoS One
Title: Expression of Toll-like receptors in the developing brain.
Volume: 7
Issue: 5
Pages: e37767
Publication
First Author: De Luca A
Year: 2013
Journal: PLoS Pathog
Title: IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis.
Volume: 9
Issue: 7
Pages: e1003486
Publication
First Author: Onishi M
Year: 2015
Journal: J Immunol
Title: Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Volume: 194
Issue: 6
Pages: 2673-82
Publication  
First Author: Yiu JHC
Year: 2021
Journal: Front Cell Dev Biol
Title: TLR5 Supports Development of Placental Labyrinthine Zone in Mice.
Volume: 9
Pages: 711253
Publication
First Author: Saeed H
Year: 2011
Journal: J Bone Miner Res
Title: Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.
Volume: 26
Issue: 7
Pages: 1494-505
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Strain
Attribute String: congenic, mutant strain, targeted mutation
GO Term
Allele
Name: toll-like receptor 6; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
GO Term
GO Term
GO Term
Publication
First Author: Hajjar AM
Year: 2001
Journal: J Immunol
Title: Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.
Volume: 166
Issue: 1
Pages: 15-9
Publication
First Author: Droemann D
Year: 2003
Journal: Histochem Cell Biol
Title: Toll-like receptor 2 is expressed by alveolar epithelial cells type II and macrophages in the human lung.
Volume: 119
Issue: 2
Pages: 103-8
Publication
First Author: Sheedy FJ
Year: 2007
Journal: J Leukoc Biol
Title: The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling.
Volume: 82
Issue: 2
Pages: 196-203
Publication
First Author: Bochud PY
Year: 2008
Journal: J Infect Dis
Title: Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy.
Volume: 197
Issue: 2
Pages: 253-61
Publication
First Author: Aliprantis AO
Year: 1999
Journal: Science
Title: Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2.
Volume: 285
Issue: 5428
Pages: 736-9
Publication
First Author: Bochud PY
Year: 2003
Journal: J Immunol
Title: Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling.
Volume: 170
Issue: 7
Pages: 3451-4
Publication
First Author: Schröder NW
Year: 2003
Journal: J Biol Chem
Title: Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved.
Volume: 278
Issue: 18
Pages: 15587-94
Publication
First Author: Kirschning CJ
Year: 2001
Journal: Int J Med Microbiol
Title: Toll-like receptors: cellular signal transducers for exogenous molecular patterns causing immune responses.
Volume: 291
Issue: 4
Pages: 251-60
Protein Domain
Type: Family
Description: Toll-like receptor 2 (TLR2) is a member of the Toll-like receptor (TLR) family, which plays a role in activation of innate immunity and pathogen recognition []. It helps mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components, acting via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response [, , , ]. TLR2 in association with TLR1 or TLR6 is essential for recognising bacterial lipoproteins and lipopeptides [, ]. It also promotes apoptosis in response to lipoproteins [].Genetic variations in TLR2 are associated with susceptibility to leprosy, a chronic disease associated with depressed cellular (but not humoral) immunity [, ].
Publication
First Author: Jin MS
Year: 2007
Journal: Cell
Title: Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide.
Volume: 130
Issue: 6
Pages: 1071-82
Publication
First Author: Love W
Year: 2010
Journal: PLoS One
Title: Toll-like receptor 2 (TLR2) plays a major role in innate resistance in the lung against murine Mycoplasma.
Volume: 5
Issue: 5
Pages: e10739
Publication
First Author: Koymans KJ
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3).
Volume: 112
Issue: 35
Pages: 11018-23
Publication
First Author: Jeyaseelan S
Year: 2006
Journal: J Immunol
Title: Toll/IL-1R domain-containing adaptor protein (TIRAP) is a critical mediator of antibacterial defense in the lung against Klebsiella pneumoniae but not Pseudomonas aeruginosa.
Volume: 177
Issue: 1
Pages: 538-47
Publication
First Author: Zahoor A
Year: 2020
Journal: J Cell Physiol
Title: Gas6 negatively regulates the Staphylococcus aureus-induced inflammatory response via TLR signaling in the mouse mammary gland.
Volume: 235
Issue: 10
Pages: 7081-7093
Publication
First Author: Hope C
Year: 2014
Journal: Blood
Title: TPL2 kinase regulates the inflammatory milieu of the myeloma niche.
Volume: 123
Issue: 21
Pages: 3305-15
Publication
First Author: Jang YH
Year: 2017
Journal: J Invest Dermatol
Title: House Dust Mite Increases pro-Th2 Cytokines IL-25 and IL-33 via the Activation of TLR1/6 Signaling.
Volume: 137
Issue: 11
Pages: 2354-2361