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Search results 2301 to 2400 out of 3582 for Tlr4

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Type Details Score
Publication
21239713 | J:169160
First Author: Enoksson M
Year: 2011
Journal: J Immunol
Title: Mast cells as sensors of cell injury through IL-33 recognition.
Volume: 186
Issue: 4
Pages: 2523-8
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Publication
30699352 | J:280552
First Author: Cousin C
Year: 2019
Journal: Cell Rep
Title: Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses.
Volume: 26
Issue: 5
Pages: 1242-1257.e7
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Publication
21474346 | J:171355
First Author: Kool M
Year: 2011
Journal: Immunity
Title: An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma.
Volume: 34
Issue: 4
Pages: 527-40
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Publication
22634614 | J:188954
First Author: Eigenbrod T
Year: 2012
Journal: J Immunol
Title: Bacterial RNA mediates activation of caspase-1 and IL-1β release independently of TLRs 3, 7, 9 and TRIF but is dependent on UNC93B.
Volume: 189
Issue: 1
Pages: 328-36
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Publication
24722226 | J:247229
First Author: Wagener J
Year: 2014
Journal: PLoS Pathog
Title: Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.
Volume: 10
Issue: 4
Pages: e1004050
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Publication
17433728 | J:123579
First Author: Kanneganti TD
Year: 2007
Journal: Immunity
Title: Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling.
Volume: 26
Issue: 4
Pages: 433-43
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Publication
22323544 | J:181854
First Author: Lacroix-Lamandé S
Year: 2012
Journal: J Immunol
Title: Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome.
Volume: 188
Issue: 6
Pages: 2805-14
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Publication
31293597 | J:283609
 
First Author: Shimizu K
Year: 2019
Journal: Front Immunol
Title: Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN.
Volume: 10
Pages: 1450
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Publication
32515732 | J:294830
   
First Author: Kim EH
Year: 2020
Journal: Elife
Title: Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.
Volume: 9
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Publication
24362933 | J:226672
First Author: Liehl P
Year: 2014
Journal: Nat Med
Title: Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.
Volume: 20
Issue: 1
Pages: 47-53
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Publication
34341449 | J:359911
First Author: de Queiroz NMGP
Year: 2021
Journal: Sci Rep
Title: MyD88-dependent BCG immunotherapy reduces tumor and regulates tumor microenvironment in bladder cancer murine model.
Volume: 11
Issue: 1
Pages: 15648
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Publication
29459437 | J:258482
 
First Author: Santos JC
Year: 2018
Journal: EMBO J
Title: LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.
Volume: 37
Issue: 6
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Publication
35263589 | J:324853
First Author: Sugisawa E
Year: 2022
Journal: Cell Rep
Title: Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia.
Volume: 38
Issue: 10
Pages: 110462
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Publication
18180310 | J:131122
First Author: Ip WK
Year: 2008
Journal: J Exp Med
Title: Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome.
Volume: 205
Issue: 1
Pages: 169-81
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Publication
37870318 | J:358168
First Author: Wang Y
Year: 2023
Journal: EMBO Rep
Title: Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL-1R/TLR signals.
Volume: 24
Issue: 12
Pages: e57485
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Publication
33239787 | J:338001
First Author: Gola A
Year: 2021
Journal: Nature
Title: Commensal-driven immune zonation of the liver promotes host defence.
Volume: 589
Issue: 7840
Pages: 131-136
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32668198 | J:348049
First Author: Winkler ES
Year: 2020
Journal: Cell
Title: The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis.
Volume: 182
Issue: 4
Pages: 901-918.e18
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31086261 | J:282944
First Author: Polykratis A
Year: 2019
Journal: Nat Cell Biol
Title: A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.
Volume: 21
Issue: 6
Pages: 731-742
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33412104 | J:320744
First Author: Koren N
Year: 2021
Journal: Cell Host Microbe
Title: Maturation of the neonatal oral mucosa involves unique epithelium-microbiota interactions.
Volume: 29
Issue: 2
Pages: 197-209.e5
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Publication
16260493 | J:102721
First Author: Shim JH
Year: 2005
Journal: Genes Dev
Title: TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo.
Volume: 19
Issue: 22
Pages: 2668-81
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19382893 | J:150494
First Author: Kumar H
Year: 2009
Journal: Biochem J
Title: Pathogen recognition in the innate immune response.
Volume: 420
Issue: 1
Pages: 1-16
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18261938 | J:132126
First Author: Kim YG
Year: 2008
Journal: Immunity
Title: The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands.
Volume: 28
Issue: 2
Pages: 246-57
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Publication
17488888 | J:127224
First Author: Prows DR
Year: 2007
Journal: Physiol Genomics
Title: Genetic analysis of hyperoxic acute lung injury survival in reciprocal intercross mice.
Volume: 30
Issue: 3
Pages: 271-81
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18287966 | J:135431
First Author: Salminen A
Year: 2008
Journal: Pediatr Res
Title: Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines.
Volume: 63
Issue: 3
Pages: 280-6
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18378686 | J:137555
First Author: Kim YI
Year: 2008
Journal: J Biol Chem
Title: CpG DNA prevents liver injury and shock-mediated death by modulating expression of interleukin-1 receptor-associated kinases.
Volume: 283
Issue: 22
Pages: 15258-70
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21865055 | J:180111
First Author: Salminen A
Year: 2011
Journal: Cytokine
Title: Surfactant protein A modulates the lipopolysaccharide-induced inflammatory response related to preterm birth.
Volume: 56
Issue: 2
Pages: 442-9
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Publication
24827856 | J:217355
First Author: Kupz A
Year: 2014
Journal: PLoS One
Title: In vivo IFN-γ secretion by NK cells in response to Salmonella typhimurium requires NLRC4 inflammasomes.
Volume: 9
Issue: 5
Pages: e97418
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Publication
31729371 | J:281617
First Author: Balounová J
Year: 2019
Journal: Nat Commun
Title: Toll-like receptor 2 expression on c-kit+ cells tracks the emergence of embryonic definitive hematopoietic progenitors.
Volume: 10
Issue: 1
Pages: 5176
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Publication
27339979 | J:233302
First Author: Birchenough GM
Year: 2016
Journal: Science
Title: A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion.
Volume: 352
Issue: 6293
Pages: 1535-42
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18480244 | J:148644
First Author: Hayashi T
Year: 2008
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Mast cell-dependent anorexia and hypothermia induced by mucosal activation of Toll-like receptor 7.
Volume: 295
Issue: 1
Pages: R123-32
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Publication
35417681 | J:334663
First Author: Iberg CA
Year: 2022
Journal: Cell Rep
Title: TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells.
Volume: 39
Issue: 2
Pages: 110657
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Publication
29576482 | J:272677
First Author: Hernández-Santos N
Year: 2018
Journal: Cell Host Microbe
Title: Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.
Volume: 23
Issue: 4
Pages: 511-522.e5
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Publication
24453255 | J:209447
First Author: Gurung P
Year: 2014
Journal: J Immunol
Title: FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.
Volume: 192
Issue: 4
Pages: 1835-46
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Publication
23853597 | J:213365
First Author: De Luca A
Year: 2013
Journal: PLoS Pathog
Title: IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis.
Volume: 9
Issue: 7
Pages: e1003486
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Publication
32632165 | J:294172
First Author: Kawabe T
Year: 2020
Journal: Nat Commun
Title: Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state.
Volume: 11
Issue: 1
Pages: 3366
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Publication
18516037 | J:137710
First Author: Uematsu S
Year: 2008
Journal: Nat Immunol
Title: Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.
Volume: 9
Issue: 7
Pages: 769-76
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Publication
22840842 | J:187388
First Author: Vladimer GI
Year: 2012
Journal: Immunity
Title: The NLRP12 inflammasome recognizes Yersinia pestis.
Volume: 37
Issue: 1
Pages: 96-107
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Publication
32150572 | J:287406
First Author: Place DE
Year: 2020
Journal: PLoS Pathog
Title: Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.
Volume: 16
Issue: 3
Pages: e1008364
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Publication
30510167 | J:287363
First Author: Briard B
Year: 2019
Journal: Nat Microbiol
Title: Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection.
Volume: 4
Issue: 2
Pages: 316-327
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Publication
28002730 | J:291647
First Author: Kuroda E
Year: 2016
Journal: Immunity
Title: Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation.
Volume: 45
Issue: 6
Pages: 1299-1310
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Publication
27374884 | J:291655
 
First Author: Hayashi M
Year: 2016
Journal: Sci Rep
Title: RNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, Endocine.
Volume: 6
Pages: 29165
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Publication
20668698 | J:163082
First Author: Koh YS
Year: 2010
Journal: PLoS One
Title: MyD88-dependent signaling contributes to host defense against ehrlichial infection.
Volume: 5
Issue: 7
Pages: e11758
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Publication
32708537 | J:302364
 
First Author: Gausserès B
Year: 2020
Journal: Biomolecules
Title: The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse.
Volume: 10
Issue: 7
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Publication
26311113 | J:283846
First Author: Hirsch S
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: A mouse model of Townes-Brocks syndrome expressing a truncated mutant Sall1 protein is protected from acute kidney injury.
Volume: 309
Issue: 10
Pages: F852-63
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Publication
22666391 | J:187296
First Author: Kaul D
Year: 2012
Journal: PLoS One
Title: Expression of Toll-like receptors in the developing brain.
Volume: 7
Issue: 5
Pages: e37767
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Publication
31907354 | J:309350
First Author: Estrada SM
Year: 2020
Journal: Cell Death Dis
Title: The orphan nuclear receptor Nr4a1 mediates perinatal neuroinflammation in a murine model of preterm labor.
Volume: 11
Issue: 1
Pages: 11
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Publication
38744293 | J:349097
     
First Author: Imai T
Year: 2024
Journal: Immunity
Title: The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation.
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Publication
34678150 | J:337628
First Author: Xue G
Year: 2021
Journal: Cancer Cell
Title: Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells.
Volume: 39
Issue: 12
Pages: 1610-1622.e9
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Publication
27189410 | J:239926
 
First Author: Ronchi F
Year: 2016
Journal: Nat Commun
Title: Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1β production by myeloid cells.
Volume: 7
Pages: 11541
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Publication
34395439 | J:310855
 
First Author: Yiu JHC
Year: 2021
Journal: Front Cell Dev Biol
Title: TLR5 Supports Development of Placental Labyrinthine Zone in Mice.
Volume: 9
Pages: 711253
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Publication
28400473 | J:242009
First Author: Choo MK
Year: 2017
Journal: J Exp Med
Title: TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.
Volume: 214
Issue: 5
Pages: 1297-1311
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Publication
25681338 | J:274041
First Author: Onishi M
Year: 2015
Journal: J Immunol
Title: Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Volume: 194
Issue: 6
Pages: 2673-82
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Publication
23334579 | J:197476
First Author: Kierdorf K
Year: 2013
Journal: Nat Neurosci
Title: Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways.
Volume: 16
Issue: 3
Pages: 273-80
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Publication
19047410 | J:143745
First Author: Kamda JD
Year: 2009
Journal: Infect Immun
Title: Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia.
Volume: 77
Issue: 2
Pages: 685-93
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Publication
28410990 | J:254534
First Author: Gurung P
Year: 2017
Journal: Immunity
Title: Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.
Volume: 46
Issue: 4
Pages: 635-648
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Publication
27653694 | J:239115
First Author: Kurbet AS
Year: 2016
Journal: Cell Rep
Title: Sterile Inflammation Enhances ECM Degradation in Integrin β1 KO Embryonic Skin.
Volume: 16
Issue: 12
Pages: 3334-3347
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Publication
29044125 | J:255485
First Author: Li S
Year: 2017
Journal: Sci Rep
Title: Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.
Volume: 7
Issue: 1
Pages: 13427
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Publication
29438518 | J:258670
First Author: Mahany EB
Year: 2018
Journal: Endocrinology
Title: Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome.
Volume: 159
Issue: 4
Pages: 1718-1733
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Publication
35493520 | J:324243
 
First Author: Lei Z
Year: 2022
Journal: Front Immunol
Title: EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice.
Volume: 13
Pages: 843378
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
32212902 | J:317550
First Author: Sakamoto T
Year: 2020
Journal: Circ Res
Title: A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation.
Volume: 126
Issue: 12
Pages: 1685-1702
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12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Protein
Q9DBY4
Organism: Mus musculus/domesticus
Length: 809  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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