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Search results 1 to 100 out of 421 for Ptpn11

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Category: Publication
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Type Details Score
Publication
25289670 | J:222457
First Author: Usenko T
Year: 2014
Journal: PLoS One
Title: Leukemogenic Ptpn11 allele causes defective erythropoiesis in mice.
Volume: 9
Issue: 10
Pages: e109682
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Publication
28463680 | J:257090
   
First Author: Griger J
Year: 2017
Journal: Elife
Title: Loss of Ptpn11 (Shp2) drives satellite cells into quiescence.
Volume: 6
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Publication
18640765 | J:142002
First Author: Yang Z
Year: 2008
Journal: Exp Hematol
Title: Activating PTPN11 mutants promote hematopoietic progenitor cell-cycle progression and survival.
Volume: 36
Issue: 10
Pages: 1285-96
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Publication
22058153 | J:181656
First Author: Schramm C
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: The PTPN11 loss-of-function mutation Q510E-Shp2 causes hypertrophic cardiomyopathy by dysregulating mTOR signaling.
Volume: 302
Issue: 1
Pages: H231-43
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Publication
21398220 | J:173832
First Author: Chan G
Year: 2011
Journal: Blood
Title: Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.
Volume: 117
Issue: 16
Pages: 4253-61
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Publication
27783593 | J:239412
First Author: Dong L
Year: 2016
Journal: Nature
Title: Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment.
Volume: 539
Issue: 7628
Pages: 304-308
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Publication
23863940 | J:204745
First Author: Yang W
Year: 2013
Journal: Nature
Title: Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling.
Volume: 499
Issue: 7459
Pages: 491-5
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Publication
26755576 | J:229927
First Author: Liu X
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Gain-of-function mutations of Ptpn11 (Shp2) cause aberrant mitosis and increase susceptibility to DNA damage-induced malignancies.
Volume: 113
Issue: 4
Pages: 984-9
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Publication
19179468 | J:148430
First Author: Chan G
Year: 2009
Journal: Blood
Title: Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesis.
Volume: 113
Issue: 18
Pages: 4414-24
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Publication
21339643 | J:172033
First Author: Marin TM
Year: 2011
Journal: J Clin Invest
Title: Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.
Volume: 121
Issue: 3
Pages: 1026-43
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Publication
36194675 | J:333063
First Author: Ventura PMO
Year: 2022
Journal: EMBO Rep
Title: Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses.
Volume: 23
Issue: 11
Pages: e55399
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Publication
19251646 | J:147154
First Author: Araki T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Noonan syndrome cardiac defects are caused by PTPN11 acting in endocardium to enhance endocardial-mesenchymal transformation.
Volume: 106
Issue: 12
Pages: 4736-41
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Publication
27840422 | J:241807
First Author: Liu W
Year: 2017
Journal: Leukemia
Title: Inhibition of the Gab2/PI3K/mTOR signaling ameliorates myeloid malignancy caused by Ptpn11 (Shp2) gain-of-function mutations.
Volume: 31
Issue: 6
Pages: 1415-1422
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Publication
23675459 | J:202176
First Author: Xu D
Year: 2013
Journal: PLoS One
Title: Activating mutations in protein tyrosine phosphatase Ptpn11 (Shp2) enhance reactive oxygen species production that contributes to myeloproliferative disorder.
Volume: 8
Issue: 5
Pages: e63152
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Publication
15273746 | J:91609
First Author: Araki T
Year: 2004
Journal: Nat Med
Title: Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.
Volume: 10
Issue: 8
Pages: 849-57
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Publication
19509418 | J:153461
First Author: Zhang W
Year: 2009
Journal: J Biol Chem
Title: Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia.
Volume: 284
Issue: 33
Pages: 22353-63
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Publication
25650089 | J:221972
First Author: Chen L
Year: 2015
Journal: Leukemia
Title: Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition.
Volume: 29
Issue: 6
Pages: 1290-300
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20651068 | J:166477
First Author: Xu D
Year: 2010
Journal: Blood
Title: A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells.
Volume: 116
Issue: 18
Pages: 3611-21
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Publication
21930766 | J:177285
First Author: Xu D
Year: 2011
Journal: J Exp Med
Title: Non-lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells.
Volume: 208
Issue: 10
Pages: 1977-88
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Publication
19528235 | J:151520
First Author: Yang Z
Year: 2009
Journal: Mol Cell Biol
Title: Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutants.
Volume: 29
Issue: 16
Pages: 4376-93
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Publication
23884424 | J:203541
First Author: Zheng H
Year: 2013
Journal: J Biol Chem
Title: Induction of a tumor-associated activating mutation in protein tyrosine phosphatase Ptpn11 (Shp2) enhances mitochondrial metabolism, leading to oxidative stress and senescence.
Volume: 288
Issue: 36
Pages: 25727-38
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28975680 | J:249974
First Author: Tarnawsky SP
Year: 2017
Journal: Dev Dyn
Title: Yolk sac erythromyeloid progenitors expressing gain of function PTPN11 have functional features of JMML but are not sufficient to cause disease in mice.
Volume: 246
Issue: 12
Pages: 1001-1014
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18316486 | J:148445
First Author: Kontaridis MI
Year: 2008
Journal: Circulation
Title: Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways.
Volume: 117
Issue: 11
Pages: 1423-35
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30355677 | J:271155
First Author: Hill KS
Year: 2019
Journal: Mol Cancer Res
Title: PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas.
Volume: 17
Issue: 2
Pages: 583-593
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24865967 | J:223678
First Author: Paardekooper Overman J
Year: 2014
Journal: Mol Cell Biol
Title: PZR coordinates Shp2 Noonan and LEOPARD syndrome signaling in zebrafish and mice.
Volume: 34
Issue: 15
Pages: 2874-89
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25359717 | J:237450
First Author: Edwards MA
Year: 2015
Journal: J Appl Physiol (1985)
Title: The Q510E mutation in Shp2 perturbs heart valve development by increasing cell migration.
Volume: 118
Issue: 1
Pages: 124-31
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30467378 | J:294542
First Author: Zhao H
Year: 2019
Journal: Oncogene
Title: Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis.
Volume: 38
Issue: 13
Pages: 2275-2290
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31562133 | J:285765
First Author: Bellio M
Year: 2019
Journal: Blood
Title: Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions.
Volume: 134
Issue: 25
Pages: 2304-2317
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27942593 | J:293588
First Author: Yi JS
Year: 2016
Journal: JCI Insight
Title: Low-dose dasatinib rescues cardiac function in Noonan syndrome.
Volume: 1
Issue: 20
Pages: e90220
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25538234 | J:232693
First Author: Li XJ
Year: 2015
Journal: J Biol Chem
Title: Protein-tyrosine phosphatase Shp2 positively regulates macrophage oxidative burst.
Volume: 290
Issue: 7
Pages: 3894-909
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28804122 | J:253876
First Author: Gu S
Year: 2018
Journal: Leukemia
Title: SHP2 is required for BCR-ABL1-induced hematologic neoplasia.
Volume: 32
Issue: 1
Pages: 203-213
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24077964 | J:202827
First Author: Lapinski PE
Year: 2013
Journal: Dis Model Mech
Title: Deletion of SHP-2 in mesenchymal stem cells causes growth retardation, limb and chest deformity, and calvarial defects in mice.
Volume: 6
Issue: 6
Pages: 1448-58
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23530062 | J:204026
First Author: Coulombe G
Year: 2013
Journal: Mol Cell Biol
Title: Epithelial tyrosine phosphatase SHP-2 protects against intestinal inflammation in mice.
Volume: 33
Issue: 11
Pages: 2275-84
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29774106 | J:294741
First Author: Tarnawsky SP
Year: 2018
Journal: Oncotarget
Title: Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice.
Volume: 9
Issue: 31
Pages: 21831-21843
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22890240 | J:191834
First Author: Liu X
Year: 2012
Journal: Cancer Res
Title: Protein tyrosine phosphatase Shp2 (Ptpn11) plays an important role in maintenance of chromosome stability.
Volume: 72
Issue: 20
Pages: 5296-306
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27582544 | J:309023
First Author: Gagné-Sansfaçon J
Year: 2016
Journal: Oncotarget
Title: SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development.
Volume: 7
Issue: 40
Pages: 65676-65695
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19541608 | J:150835
First Author: Nakamura T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Protein tyrosine phosphatase activity in the neural crest is essential for normal heart and skull development.
Volume: 106
Issue: 27
Pages: 11270-5
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32584792 | J:301775
 
First Author: Yi JS
Year: 2020
Journal: JCI Insight
Title: Tyrosyl phosphorylation of PZR promotes hypertrophic cardiomyopathy in PTPN11-associated Noonan syndrome with multiple lentigines.
Volume: 5
Issue: 15
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28582432 | J:246003
First Author: Wang J
Year: 2017
Journal: PLoS One
Title: In vivo efficacy of the AKT inhibitor ARQ 092 in Noonan Syndrome with multiple lentigines-associated hypertrophic cardiomyopathy.
Volume: 12
Issue: 6
Pages: e0178905
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33689087 | J:307835
     
First Author: Yi JS
Year: 2021
Journal: Cardiovasc Drugs Ther
Title: Low-dose Dasatinib Ameliorates Hypertrophic Cardiomyopathy in Noonan Syndrome with Multiple Lentigines.
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Publication
24875294 | J:226886
First Author: Bowen ME
Year: 2014
Journal: PLoS Genet
Title: SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates.
Volume: 10
Issue: 5
Pages: e1004364
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25288766 | J:216593
First Author: Tajan M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity.
Volume: 111
Issue: 42
Pages: E4494-503
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29644115 | J:287059
 
First Author: Zuo C
Year: 2018
Journal: Bone Res
Title: SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity.
Volume: 6
Pages: 12
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Publication
29559584 | J:284401
 
First Author: Zheng H
Year: 2018
Journal: Sci Signal
Title: Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner.
Volume: 11
Issue: 522
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10742110 | J:61487
First Author: Saxton TM
Year: 2000
Journal: Nat Genet
Title: The SH2 tyrosine phosphatase shp2 is required for mammalian limb development.
Volume: 24
Issue: 4
Pages: 420-3
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29464054 | J:310955
First Author: Deng L
Year: 2018
Journal: Oncotarget
Title: Rapid development of myeloproliferative neoplasm in mice with Ptpn11D61Y mutation and haploinsufficient for Dnmt3a.
Volume: 9
Issue: 5
Pages: 6055-6061
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28346493 | J:242312
First Author: Altmüller F
Year: 2017
Journal: PLoS Genet
Title: Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.
Volume: 13
Issue: 3
Pages: e1006684
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33165997 | J:308779
First Author: Wang L
Year: 2021
Journal: FASEB J
Title: SHP2 regulates the development of intestinal epithelium by modifying OSTERIX+ crypt stem cell self-renewal and proliferation.
Volume: 35
Issue: 1
Pages: e21106
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22371576 | J:182238
First Author: De Rocca Serra-Nédélec A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature.
Volume: 109
Issue: 11
Pages: 4257-62
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29046360 | J:270161
First Author: Wang L
Year: 2018
Journal: FASEB J
Title: A ERK/RSK-mediated negative feedback loop regulates M-CSF-evoked PI3K/AKT activation in macrophages.
Volume: 32
Issue: 2
Pages: 875-887
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10700187 | J:60750
First Author: Chen B
Year: 2000
Journal: Nat Genet
Title: Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis.
Volume: 24
Issue: 3
Pages: 296-9
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24599474 | J:209617
First Author: Ehrman LA
Year: 2014
Journal: J Neurosci
Title: The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon.
Volume: 34
Issue: 10
Pages: 3767-78
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29808009 | J:336458
First Author: Ruess DA
Year: 2018
Journal: Nat Med
Title: Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Volume: 24
Issue: 7
Pages: 954-960
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12219085 | J:79073
First Author: Tebbutt NC
Year: 2002
Journal: Nat Med
Title: Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice.
Volume: 8
Issue: 10
Pages: 1089-97
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31634485 | J:294628
 
First Author: Gong H
Year: 2019
Journal: J Mol Cell Cardiol
Title: Shp2 in myocytes is essential for cardiovascular and neointima development.
Volume: 137
Pages: 71-81
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24431450 | J:205567
First Author: Li K
Year: 2014
Journal: J Neurosci
Title: Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum.
Volume: 34
Issue: 3
Pages: 922-31
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19017799 | J:142212
First Author: Krenz M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome.
Volume: 105
Issue: 48
Pages: 18930-5
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16179375 | J:126616
First Author: Ai J
Year: 2006
Journal: Blood
Title: The inositol phosphatase SHIP-2 down-regulates FcgammaR-mediated phagocytosis in murine macrophages independently of SHIP-1.
Volume: 107
Issue: 2
Pages: 813-20
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16272304 | J:119396
First Author: Salmond RJ
Year: 2005
Journal: J Immunol
Title: The src homology 2 domain-containing tyrosine phosphatase 2 regulates primary T-dependent immune responses and Th cell differentiation.
Volume: 175
Issue: 10
Pages: 6498-508
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17015617 | J:114499
First Author: Fornaro M
Year: 2006
Journal: J Cell Biol
Title: SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth.
Volume: 175
Issue: 1
Pages: 87-97
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26644409 | J:236136
First Author: Verma R
Year: 2015
Journal: Mol Cell Biol
Title: Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury.
Volume: 36
Issue: 4
Pages: 596-614
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25383899 | J:219527
First Author: Lee YS
Year: 2014
Journal: Nat Neurosci
Title: Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome.
Volume: 17
Issue: 12
Pages: 1736-43
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16516835 | J:106624
First Author: Yang W
Year: 2006
Journal: Dev Cell
Title: An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival.
Volume: 10
Issue: 3
Pages: 317-27
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24706815 | J:208629
First Author: Lajiness JD
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: SHP-2 deletion in postmigratory neural crest cells results in impaired cardiac sympathetic innervation.
Volume: 111
Issue: 14
Pages: E1374-82
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30089263 | J:270949
First Author: Levy AD
Year: 2018
Journal: Cell Rep
Title: Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function.
Volume: 24
Issue: 6
Pages: 1523-1535
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19008228 | J:145564
First Author: Wang S
Year: 2009
Journal: J Biol Chem
Title: Noonan syndrome/leukemia-associated gain-of-function mutations in SHP-2 phosphatase (PTPN11) enhance cell migration and angiogenesis.
Volume: 284
Issue: 2
Pages: 913-20
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33910978 | J:310504
 
First Author: Paccoud R
Year: 2021
Journal: Sci Transl Med
Title: SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations.
Volume: 13
Issue: 591
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9271425 | J:42361
First Author: Qu CK
Year: 1997
Journal: Mol Cell Biol
Title: A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development.
Volume: 17
Issue: 9
Pages: 5499-507
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16939816 | J:116262
First Author: Chan RJ
Year: 2006
Journal: Exp Hematol
Title: Shp-2 heterozygous hematopoietic stem cells have deficient repopulating ability due to diminished self-renewal.
Volume: 34
Issue: 9
Pages: 1230-9
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21636860 | J:174862
First Author: Futami M
Year: 2011
Journal: Blood
Title: G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase.
Volume: 118
Issue: 4
Pages: 1077-86
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9742124 | J:50297
First Author: Qu CK
Year: 1998
Journal: Mol Cell Biol
Title: Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells.
Volume: 18
Issue: 10
Pages: 6075-82
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20734316 | J:175592
First Author: David FS
Year: 2010
Journal: Anat Rec (Hoboken)
Title: Regulation of kidney development by Shp2: an unbiased stereological analysis.
Volume: 293
Issue: 12
Pages: 2147-53
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17157040 | J:116705
First Author: An H
Year: 2006
Journal: Immunity
Title: SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production.
Volume: 25
Issue: 6
Pages: 919-28
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25736378 | J:222985
First Author: Lan L
Year: 2015
Journal: EMBO J
Title: Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.
Volume: 34
Issue: 11
Pages: 1493-508
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28352079 | J:275262
First Author: Hsu MF
Year: 2017
Journal: Sci Rep
Title: Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria.
Volume: 7
Issue: 1
Pages: 461
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21353259 | J:198409
First Author: Bettaieb A
Year: 2011
Journal: Metabolism
Title: Adipose-specific deletion of Src homology phosphatase 2 does not significantly alter systemic glucose homeostasis.
Volume: 60
Issue: 8
Pages: 1193-201
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20841350 | J:167406
First Author: Matsuo K
Year: 2010
Journal: J Biol Chem
Title: Altered glucose homeostasis in mice with liver-specific deletion of Src homology phosphatase 2.
Volume: 285
Issue: 51
Pages: 39750-8
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22619361 | J:189120
First Author: Nagata N
Year: 2012
Journal: Endocrinology
Title: Hepatic Src homology phosphatase 2 regulates energy balance in mice.
Volume: 153
Issue: 7
Pages: 3158-69
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Publication
30471432 | J:270654
 
First Author: Wang L
Year: 2019
Journal: Bone
Title: SHP2 regulates intramembranous ossification by modifying the TGFβ and BMP2 signaling pathway.
Volume: 120
Pages: 327-335
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8702915 | J:35137
First Author: Arrandale JM
Year: 1996
Journal: J Biol Chem
Title: Insulin signaling in mice expressing reduced levels of Syp.
Volume: 271
Issue: 35
Pages: 21353-8
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29257282 | J:271783
First Author: Zhu Y
Year: 2018
Journal: Mol Med Rep
Title: Loss of Shp2 within radial glia is associated with cerebral cortical dysplasia, glial defects of cerebellum and impaired sensory‑motor development in newborn mice.
Volume: 17
Issue: 2
Pages: 3170-3177
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Publication
22891281 | J:189811
First Author: Li FF
Year: 2012
Journal: J Immunol
Title: Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation.
Volume: 189
Issue: 6
Pages: 3159-67
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Publication
25339680 | J:223881
First Author: do Carmo JM
Year: 2014
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Shp2 signaling in POMC neurons is important for leptin's actions on blood pressure, energy balance, and glucose regulation.
Volume: 307
Issue: 12
Pages: R1438-47
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Publication
19290061 | J:147360
First Author: Wu D
Year: 2009
Journal: PLoS One
Title: A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase.
Volume: 4
Issue: 3
Pages: e4914
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Publication
24030516 | J:202690
First Author: do Carmo JM
Year: 2014
Journal: Int J Obes (Lond)
Title: Role of Shp2 in forebrain neurons in regulating metabolic and cardiovascular functions and responses to leptin.
Volume: 38
Issue: 6
Pages: 775-83
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Publication
32350404 | J:331281
First Author: Xu Y
Year: 2021
Journal: Cell Mol Immunol
Title: Tyrosine phosphatase Shp2 regulates p115RhoGEF/Rho-dependent dendritic cell migration.
Volume: 18
Issue: 3
Pages: 755-757
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Publication
23873233 | J:324822
First Author: Kim HK
Year: 2013
Journal: Spine (Phila Pa 1976)
Title: Induction of SHP2 deficiency in chondrocytes causes severe scoliosis and kyphosis in mice.
Volume: 38
Issue: 21
Pages: E1307-12
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Publication
19786542 | J:153823
First Author: McPherson VA
Year: 2009
Journal: J Immunol
Title: SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells.
Volume: 183
Issue: 8
Pages: 4940-7
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Publication
24933319 | J:215932
First Author: Wang X
Year: 2014
Journal: J Invest Dermatol
Title: Trichomide A, a natural cyclodepsipeptide, exerts immunosuppressive activity against activated T lymphocytes by upregulating SHP2 activation to overcome contact dermatitis.
Volume: 134
Issue: 11
Pages: 2737-2746
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Publication
22362894 | J:187436
First Author: Zhang X
Year: 2012
Journal: FASEB J
Title: Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis.
Volume: 26
Issue: 6
Pages: 2338-50
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Publication
37473759 | J:341126
First Author: Luo Q
Year: 2023
Journal: Immunity
Title: An autonomous activation of interleukin-17 receptor signaling sustains inflammation and promotes disease progression.
Volume: 56
Issue: 9
Pages: 2006-2020.e6
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Publication
24123360 | J:206762
First Author: Puri P
Year: 2014
Journal: Stem Cells
Title: The transition from stem cell to progenitor spermatogonia and male fertility requires the SHP2 protein tyrosine phosphatase.
Volume: 32
Issue: 3
Pages: 741-53
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Publication
19380737 | J:148327
First Author: Zhang SS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cells.
Volume: 106
Issue: 18
Pages: 7531-6
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Publication
34728626 | J:314738
First Author: Xu Z
Year: 2021
Journal: Nat Commun
Title: Endothelial deletion of SHP2 suppresses tumor angiogenesis and promotes vascular normalization.
Volume: 12
Issue: 1
Pages: 6310
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Publication
35243230 | J:321641
First Author: Liu P
Year: 2022
Journal: iScience
Title: Endothelial Shp2 deficiency controls alternative activation of macrophage preventing radiation-induced lung injury through notch signaling.
Volume: 25
Issue: 3
Pages: 103867
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Publication
16959766 | J:117202
First Author: Ke Y
Year: 2006
Journal: J Biol Chem
Title: Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation.
Volume: 281
Issue: 45
Pages: 34374-80
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Publication
25919282 | J:270424
First Author: Kamiya N
Year: 2015
Journal: J Bone Miner Res
Title: SHP2-Deficiency in Chondrocytes Deforms Orofacial Cartilage and Ciliogenesis in Mice.
Volume: 30
Issue: 11
Pages: 2028-32
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Publication
23929766 | J:233244
First Author: Kim HK
Year: 2014
Journal: J Bone Miner Res
Title: Targeted disruption of Shp2 in chondrocytes leads to metachondromatosis with multiple cartilaginous protrusions.
Volume: 29
Issue: 3
Pages: 761-9
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Publication
23103841 | J:193632
First Author: Nabinger SC
Year: 2013
Journal: Leukemia
Title: The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo.
Volume: 27
Issue: 2
Pages: 398-408
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Publication
17056523 | J:140530
First Author: Nguyen TV
Year: 2006
Journal: J Immunol
Title: Conditional deletion of Shp2 tyrosine phosphatase in thymocytes suppresses both pre-TCR and TCR signals.
Volume: 177
Issue: 9
Pages: 5990-6
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