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Search results 601 to 652 out of 652 for Ptpn11

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0.021s

Type

Details

Score

Publication

19109195 | J:142883

First Author:	Nowell MA
Year:	2009
Journal:	J Immunol
Title:	Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis.
Volume:	182
Issue:	1
Pages:	613-22

•

Publication

22268122 | J:183951

First Author:	Ruwanpura SM
Year:	2012
Journal:	Am J Physiol Lung Cell Mol Physiol
Title:	Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice.
Volume:	302
Issue:	7
Pages:	L627-39

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Publication

37272871 | J:340869

First Author:	Millrine D
Year:	2023
Journal:	J Immunol
Title:	Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements.
Volume:	211
Issue:	2
Pages:	274-286

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Publication

26848037 | J:288464

First Author:	Däbritz J
Year:	2016
Journal:	Sci Rep
Title:	Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived suppressor cells.
Volume:	6

Pages:	20584

•

Publication

19706403 | J:153094

First Author:	Nakamura T
Year:	2009
Journal:	Proc Natl Acad Sci U S A
Title:	Noonan syndrome is associated with enhanced pERK activity, the repression of which can prevent craniofacial malformations.
Volume:	106
Issue:	36
Pages:	15436-41

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Publication

28911943 | J:257166

First Author:	Roy R
Year:	2017
Journal:	J Mol Cell Cardiol
Title:	Heterozygous deletion of AKT1 rescues cardiac contractility, but not hypertrophy, in a mouse model of Noonan Syndrome with Multiple Lentigines.
Volume:	112

Pages:	83-90

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Publication

35677533 | J:326621

First Author:	Tran CP
Year:	2022
Journal:	Oncotarget
Title:	IL-33 promotes gastric tumour growth in concert with activation and recruitment of inflammatory myeloid cells.
Volume:	13

Pages:	785-799

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Publication

33181031 | J:323985

First Author:	Saad MI
Year:	2021
Journal:	Am J Respir Cell Mol Biol
Title:	ADAM17 Deficiency Protects against Pulmonary Emphysema.
Volume:	64
Issue:	2
Pages:	183-195

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Genotype

Symbol:	Tg(CAG-cat,-Ptpn11)1Rbns/? Tg(Tek-cre)12Flv/?
Background:	involves: C3H * C57BL/6 * FVB/N
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Tg(Scgb1a1-rtTA)1Jaw/? Tg(tetO-PTPN11*E76K)#Jiwu/?
Background:	involves: 129 * C57BL/6 * FVB/N
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Tg(CAG-cat,-Ptpn11*Q510E)#Krnz/? Tg(Tek-cre)1Ywa/?
Background:	involves: C57BL/6 * FVB/N * SJL
Zygosity:	cn
Has Mutant Allele:	true

•

Protein

P35235

Organism:	Mus musculus/domesticus
Length:	593
Fragment?:	false

•

Publication

25224413 | J:218683

First Author:	Bejar R
Year:	2014
Journal:	Blood
Title:	TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients.
Volume:	124
Issue:	17
Pages:	2705-12

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Publication

34625577 | J:312396

First Author:	McNamara JT
Year:	2021
Journal:	Sci Rep
Title:	SHP-2 deletion in CD4Cre expressing chondrocyte precursors leads to tumor development with wrist tropism.
Volume:	11
Issue:	1
Pages:	20006

•

Publication

20007546 | J:157731

First Author:	Caudell D
Year:	2010
Journal:	Blood
Title:	Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice.
Volume:	115
Issue:	6
Pages:	1194-203

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Publication

28213521 | J:241654

First Author:	Wills MK
Year:	2017
Journal:	J Biol Chem
Title:	Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.
Volume:	292
Issue:	14
Pages:	5748-5759

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Publication

23948300 | J:202609

First Author:	Putoczki TL
Year:	2013
Journal:	Cancer Cell
Title:	Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically.
Volume:	24
Issue:	2
Pages:	257-71

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Publication

28170160 | J:239149

First Author:	Alorro MG
Year:	2017
Journal:	Genesis
Title:	Generation of an inducible mouse model to reversibly silence Stat3.
Volume:	55
Issue:	4

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Publication

20585009 | J:178593

First Author:	Hilfiker-Kleiner D
Year:	2010
Journal:	Circulation
Title:	Continuous glycoprotein-130-mediated signal transducer and activator of transcription-3 activation promotes inflammation, left ventricular rupture, and adverse outcome in subacute myocardial infarction.
Volume:	122
Issue:	2
Pages:	145-55

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Publication

21710691 | J:175909

First Author:	Kennedy CL
Year:	2011
Journal:	J Pathol
Title:	The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17.
Volume:	225
Issue:	2
Pages:	255-64

•

Publication

23079657 | J:192030

First Author:	Tye H
Year:	2012
Journal:	Cancer Cell
Title:	STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation.
Volume:	22
Issue:	4
Pages:	466-78

•

Publication

29562203 | J:272415

First Author:	O'Reilly LA
Year:	2018
Journal:	Immunity
Title:	Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner.
Volume:	48
Issue:	3
Pages:	570-583.e8

•

Publication

23853585 | J:213369

First Author:	Carow B
Year:	2013
Journal:	PLoS Pathog
Title:	Critical and independent role for SOCS3 in either myeloid or T cells in resistance to Mycobacterium tuberculosis.
Volume:	9
Issue:	7
Pages:	e1003442

•

Publication

17641779 | J:123963

First Author:	Nakamura T
Year:	2007
Journal:	J Clin Invest
Title:	Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome.
Volume:	117
Issue:	8
Pages:	2123-32

•

Publication

24398427 | J:320713

First Author:	Stuart E
Year:	2014
Journal:	Mol Cancer Ther
Title:	Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice.
Volume:	13
Issue:	2
Pages:	468-74

•

Publication

18431520 | J:135184

First Author:	Ernst M
Year:	2008
Journal:	J Clin Invest
Title:	STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.
Volume:	118
Issue:	5
Pages:	1727-38

•

Publication

23321674 | J:194490

First Author:	Thiem S
Year:	2013
Journal:	J Clin Invest
Title:	mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice.
Volume:	123
Issue:	2
Pages:	767-81

•

Publication

37957015 | J:342593

First Author:	Thilakasiri P
Year:	2024
Journal:	Life Sci Alliance
Title:	Mechanisms of cellular crosstalk in the gastric tumor microenvironment are mediated by YAP1 and STAT3.
Volume:	7
Issue:	2

•

Publication

18641358 | J:139226

First Author:	Fielding CA
Year:	2008
Journal:	J Immunol
Title:	IL-6 regulates neutrophil trafficking during acute inflammation via STAT3.
Volume:	181
Issue:	3
Pages:	2189-95

•

Publication

15976028 | J:99865

First Author:	McLoughlin RM
Year:	2005
Journal:	Proc Natl Acad Sci U S A
Title:	IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.
Volume:	102
Issue:	27
Pages:	9589-94

•

Publication

29282220 | J:261888

First Author:	Deswaerte V
Year:	2018
Journal:	Cancer Res
Title:	Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism.
Volume:	78
Issue:	5
Pages:	1293-1307

•

Publication

14755335 | J:87612

First Author:	Sims NA
Year:	2004
Journal:	J Clin Invest
Title:	Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways.
Volume:	113
Issue:	3
Pages:	379-89

•

Publication

20382701 | J:160377

First Author:	Plum W
Year:	2010
Journal:	Am J Pathol
Title:	Lack of glycoprotein 130/signal transducer and activator of transcription 3-mediated signaling in hepatocytes enhances chronic liver injury and fibrosis progression in a model of sclerosing cholangitis.
Volume:	176
Issue:	5
Pages:	2236-46

•

Publication

17241879 | J:127268

First Author:	Pietrangelo A
Year:	2007
Journal:	Gastroenterology
Title:	STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo.
Volume:	132
Issue:	1
Pages:	294-300

•

Publication

15761498 | J:97327

First Author:	Klein C
Year:	2005
Journal:	J Clin Invest
Title:	The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury.
Volume:	115
Issue:	4
Pages:	860-9

•

Publication

18216023 | J:135290

First Author:	Dierssen U
Year:	2008
Journal:	J Biol Chem
Title:	Molecular dissection of gp130-dependent pathways in hepatocytes during liver regeneration.
Volume:	283
Issue:	15
Pages:	9886-95

•

Publication

20530204 | J:163411

First Author:	Sander LE
Year:	2010
Journal:	J Exp Med
Title:	Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function.
Volume:	207
Issue:	7
Pages:	1453-64

•

Publication

35020406 | J:334058

First Author:	Headland SE
Year:	2022
Journal:	Sci Transl Med
Title:	Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma.
Volume:	14
Issue:	627
Pages:	eabf8188

•

Genotype

Symbol:	Mapk1/Mapk1<+> Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/? Tg(Tek-cre)12Flv/?
Background:	involves: 129S2/SvPas * C3H * C57BL/6 * FVB/N
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Mapk3/Mapk3<+> Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/? Tg(Tek-cre)12Flv/?
Background:	involves: 129/Sv * C3H * C57BL/6 * FVB/N
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Mapk3/Mapk3 Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/? Tg(Tek-cre)12Flv/?
Background:	involves: 129/Sv * C3H * C57BL/6 * FVB/N
Zygosity:	cn
Has Mutant Allele:	true

•

Protein Coding Gene

MGI:95805 | Grb2

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Protein

Q60631

Organism:	Mus musculus/domesticus
Length:	217
Fragment?:	false

•

Publication

16906166 | J:112649

First Author:	Stumhofer JS
Year:	2006
Journal:	Nat Immunol
Title:	Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.
Volume:	7
Issue:	9
Pages:	937-45

•

Publication

26974160 | J:234656

First Author:	Menheniott TR
Year:	2016
Journal:	J Clin Invest
Title:	Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression.
Volume:	126
Issue:	4
Pages:	1383-400

•

Publication

21515788 | J:173204

First Author:	Haroon F
Year:	2011
Journal:	J Immunol
Title:	Gp130-dependent astrocytic survival is critical for the control of autoimmune central nervous system inflammation.
Volume:	186
Issue:	11
Pages:	6521-31

•

Publication

17114459 | J:140695

First Author:	El Kasmi KC
Year:	2006
Journal:	J Immunol
Title:	General nature of the STAT3-activated anti-inflammatory response.
Volume:	177
Issue:	11
Pages:	7880-8

•

Publication

19185844 | J:144814

First Author:	Bollrath J
Year:	2009
Journal:	Cancer Cell
Title:	gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.
Volume:	15
Issue:	2
Pages:	91-102

•

Publication

26837764 | J:231629

First Author:	Thiem S
Year:	2016
Journal:	Cancer Res
Title:	Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model.
Volume:	76
Issue:	8
Pages:	2277-87

•

Publication

25270258 | J:259053

First Author:	Phesse TJ
Year:	2014
Journal:	Sci Signal
Title:	Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.
Volume:	7
Issue:	345
Pages:	ra92

•

Publication

24069548 | J:202463

First Author:	Li J
Year:	2013
Journal:	JAKSTAT
Title:	JAK-STAT and bone metabolism.
Volume:	2
Issue:	3
Pages:	e23930

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

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