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Search results 1801 to 1900 out of 1968 for Gata3

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Strain
MGI:6475331 | C57BL/6-Gata3<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Rr338-EGFP)#Jeng | MGI:7413141
Name: transgene insertion, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Rr338<em1Jeng> | MGI:7413214
Name: regulatory region 338; endonuclease-mediated mutation 1, James Douglas Engel
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Modified regulatory region
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Allele
Tg(Gata3)C4Jeng | MGI:7413192
Name: transgene insertion C4, James Douglas Engel
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Tg(Rr340-EGFP)#Jeng | MGI:7414090
Name: transgene insertion, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-cre)2476Jeng | MGI:7442301
Name: transgene insertion 2476, James Douglas Engel
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Gata3-cre)2471Jeng | MGI:7442300
Name: transgene insertion 2471, James Douglas Engel
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Gata3*-cre)2481Jeng | MGI:7442302
Name: transgene insertion 2481, James Douglas Engel
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
1638017 | -
First Author: Orkin SH
Year: 1992
Journal: Blood
Title: GATA-binding transcription factors in hematopoietic cells.
Volume: 80
Issue: 3
Pages: 575-81
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Protein Domain
IPR016374 | TF_GATA-2/3
Type: Family
Description: GATA transcription factors mediate processes of development, differentiation, and gene expression in multiple tissues and cell types. Vertebrate GATA factors have two highly conserved zinc finger motifs and recognise a six-nucleotide motif T/AGATAG/A in target genes. They are separated into two subfamilies: 1) GATA1, GATA2, and GATA3 and 2) GATA4, GATA5, and GATA6. Members of the GATA1/2/3 subfamily are expressed in developing blood cells, where they regulate differentiation-specific gene expression in hematopoiesis []. This entry represents the GATA2 and GATA3.
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Allele
Tg(Gata3-lacZ)-4500Jeng | MGI:7413955
Name: transgene insertion -4500, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(CD2-Gata3)1Staka | MGI:3777641
Name: transgene insertion 1, Satoru Takahashi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(GATA3-EGFP)1Smal | MGI:4838415
Name: transgene insertion 1, Stavros Malas
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-lacZ)C4Jeng | MGI:7413191
Name: transgene insertion C4, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(RP23-43G17)7.1Jeng | MGI:7413114
Name: transgene insertion 7.1, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Gata1<tm5(GATA3)Sho> | MGI:2429992
 
Name: GATA binding protein 1; targeted mutation 5, Stuart Orkin
Allele Type: Targeted
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Strain
MGI:7444935 | B6.Cg-Gata3<tm1.1Hjf>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:7518201 | C57BL/6J-Gata3<em1Aben>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Gata3-lacZ)-308Jeng | MGI:7413953
Name: transgene insertion -308, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-lacZ)B125Jeng | MGI:7413189
Name: transgene insertion B125, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-lacZ)-2052Jeng | MGI:7413954
Name: transgene insertion -2052, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-lacZ)B124Jeng | MGI:7413196
Name: transgene insertion B124, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:6353574 | B6;D2-Tg(Gata3*-cre)2481Jeng/MpuRbrc
Attribute String: transgenic, mutant stock
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Genotype
Genotype
Symbol: Rr338/Rr338
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Allele
Foxm1<em1Pra> | MGI:7331325
Name: forkhead box M1; endonuclease-mediated mutation 1, Pradip Raychaudhuri
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Tg(RP23-43G17)delta7.1Jeng | MGI:7413116
Name: transgene insertion delta7.1, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Gata1/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata1/Gata1<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
15659346 | -
First Author: Cantor AB
Year: 2005
Journal: Semin Cell Dev Biol
Title: Coregulation of GATA factors by the Friend of GATA (FOG) family of multitype zinc finger proteins.
Volume: 16
Issue: 1
Pages: 117-28
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Publication
17936744 | -
First Author: Sorrentino RP
Year: 2007
Journal: Dev Biol
Title: The Friend of GATA protein U-shaped functions as a hematopoietic tumor suppressor in Drosophila.
Volume: 311
Issue: 2
Pages: 311-23
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Protein Domain
IPR039746 | FOG
Type: Family
Description: This entry represents the FOG (Friend of GATA) family, whose members are zinc finger cofactors that regulate GATA factor-activated gene transcription. There are two FOG proteins in mammals, FOG1 and FOG2. They are essential cofactors that act via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3 []. In mice, FOG1 is expressed predominantly within the hematopoietic system, while FOG2 is expressed outside of blood, mostly in heart, brain, gonads, and liver [].This entry also includes the FOG homologue from fruit flies, U-shaped (Ush), which is expressed in circulating and lymph gland hemocytes, where it plays a critical role in controlling blood cell proliferation and differentiation [].
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Strain
MGI:3777782 | B6.Cg-Tg(CD2-Gata3)1Staka/StakaRbrc
Attribute String: congenic, transgenic, mutant strain
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Publication
17717199 | J:147530
First Author: Matsuno Y
Year: 2007
Journal: Am J Respir Crit Care Med
Title: Overexpression of GATA-3 protects against the development of hypersensitivity pneumonitis.
Volume: 176
Issue: 10
Pages: 1015-25
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HT Experiment
E-GEOD-15872 | Transcription profiling of mouse stomach, pylorus and duodenum tissue from E14.5 and E16.5 embryos
Series Id: GSE15872
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
GSE214389 | Single cell RNA sequencing analysis using embryonic day 9.5 placenta from control and GATA DKO mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
12100886 | J:78226
First Author: Patient RK
Year: 2002
Journal: Curr Opin Genet Dev
Title: The GATA family (vertebrates and invertebrates).
Volume: 12
Issue: 4
Pages: 416-22
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Gata3-cre)2471Jeng/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Gata3-cre)2476Jeng/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Gata3*-cre)2481Jeng/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Publication
12049724 | J:113530
First Author: Zhu J
Year: 2002
Journal: Immunity
Title: Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation.
Volume: 16
Issue: 5
Pages: 733-44
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Publication
19047684 | J:148305
First Author: Qiu LQ
Year: 2009
Journal: Blood
Title: Viperin is required for optimal Th2 responses and T-cell receptor-mediated activation of NF-kappaB and AP-1.
Volume: 113
Issue: 15
Pages: 3520-9
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Publication
32399548 | J:302511
 
First Author: He K
Year: 2020
Journal: J Exp Med
Title: Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung.
Volume: 217
Issue: 7
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Publication
15137944 | J:90018
First Author: Amsen D
Year: 2004
Journal: Cell
Title: Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.
Volume: 117
Issue: 4
Pages: 515-26
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Publication
25692701 | J:259905
First Author: Lee JY
Year: 2015
Journal: Immunity
Title: The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation.
Volume: 42
Issue: 2
Pages: 252-264
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Publication
30049704 | J:266046
First Author: Lei AH
Year: 2018
Journal: J Exp Med
Title: ICAM-1 controls development and function of ILC2.
Volume: 215
Issue: 8
Pages: 2157-2174
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Publication
28747424 | J:244473
First Author: Schwartz C
Year: 2017
Journal: J Exp Med
Title: ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
Volume: 214
Issue: 9
Pages: 2507-2521
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Publication
37285842 | J:337870
First Author: Ferreira ACF
Year: 2023
Journal: Immunity
Title: Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation.
Volume: 56
Issue: 7
Pages: 1468-1484.e7
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Publication
22425249 | J:187334
First Author: Jones-Mason ME
Year: 2012
Journal: Immunity
Title: E protein transcription factors are required for the development of CD4(+) lineage T cells.
Volume: 36
Issue: 3
Pages: 348-61
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Publication
21814277 | J:174921
First Author: Weber BN
Year: 2011
Journal: Nature
Title: A critical role for TCF-1 in T-lineage specification and differentiation.
Volume: 476
Issue: 7358
Pages: 63-8
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Publication
15699073 | J:96024
First Author: Kimura MY
Year: 2005
Journal: J Exp Med
Title: Regulation of T helper type 2 cell differentiation by murine Schnurri-2.
Volume: 201
Issue: 3
Pages: 397-408
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Publication
16874300 | J:119268
First Author: Martin P
Year: 2006
Journal: EMBO J
Title: The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation.
Volume: 25
Issue: 15
Pages: 3524-33
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Publication
24238339 | J:208988
First Author: Tumes DJ
Year: 2013
Journal: Immunity
Title: The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells.
Volume: 39
Issue: 5
Pages: 819-32
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Publication
30554919 | J:295053
First Author: Jiao X
Year: 2019
Journal: Stem Cell Reports
Title: Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool.
Volume: 12
Issue: 1
Pages: 135-151
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Publication
36798441 | J:333335
First Author: Lin SC
Year: 2023
Journal: iScience
Title: Endothelial-to-osteoblast transition in normal mouse bone development.
Volume: 26
Issue: 2
Pages: 105994
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Publication
11520462 | J:71268
First Author: Kimura M
Year: 2001
Journal: Immunity
Title: Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene.
Volume: 15
Issue: 2
Pages: 275-87
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Publication
21131966 | J:167446
First Author: Tanaka S
Year: 2011
Journal: Nat Immunol
Title: The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells.
Volume: 12
Issue: 1
Pages: 77-85
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Publication
29700302 | J:265729
First Author: Lorentsen KJ
Year: 2018
Journal: Nat Commun
Title: Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.
Volume: 9
Issue: 1
Pages: 1679
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Publication
20620941 | J:161995
First Author: Lee K
Year: 2010
Journal: Immunity
Title: Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.
Volume: 32
Issue: 6
Pages: 743-53
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Publication
16543408 | J:108963
First Author: Charles MA
Year: 2006
Journal: Mol Endocrinol
Title: Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function.
Volume: 20
Issue: 6
Pages: 1366-77
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Publication
26231117 | J:254628
First Author: Califano D
Year: 2015
Journal: Immunity
Title: Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells.
Volume: 43
Issue: 2
Pages: 354-68
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Publication
16713978 | J:113362
First Author: Yamashita M
Year: 2006
Journal: Immunity
Title: Crucial role of MLL for the maintenance of memory T helper type 2 cell responses.
Volume: 24
Issue: 5
Pages: 611-22
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Publication
17114435 | J:140599
First Author: Hosokawa H
Year: 2006
Journal: J Immunol
Title: Regulation of Th2 cell development by Polycomb group gene bmi-1 through the stabilization of GATA3.
Volume: 177
Issue: 11
Pages: 7656-64
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Publication
31723060 | J:298374
 
First Author: Sun B
Year: 2019
Journal: JCI Insight
Title: Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination.
Volume: 4
Issue: 22
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Publication
18390836 | J:138457
First Author: Guo Y
Year: 2008
Journal: Blood
Title: Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification.
Volume: 112
Issue: 3
Pages: 480-92
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Publication
19564409 | J:152618
First Author: Wang HC
Year: 2009
Journal: Mol Cell Biol
Title: Id1 attenuates Notch signaling and impairs T-cell commitment by elevating Deltex1 expression.
Volume: 29
Issue: 17
Pages: 4640-52
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Publication
35687692 | J:325970
First Author: Yang H
Year: 2022
Journal: Sci Adv
Title: The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression.
Volume: 8
Issue: 23
Pages: eabn3509
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Publication
24821970 | J:328420
First Author: Kwon SJ
Year: 2014
Journal: J Immunol
Title: KLF13 cooperates with c-Maf to regulate IL-4 expression in CD4+ T cells.
Volume: 192
Issue: 12
Pages: 5703-9
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Publication
20808283 | J:165438
First Author: Yang JQ
Year: 2010
Journal: EMBO J
Title: NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo.
Volume: 29
Issue: 19
Pages: 3421-33
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Publication
10894164 | J:111995
First Author: Agarwal S
Year: 2000
Journal: Immunity
Title: Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo.
Volume: 12
Issue: 6
Pages: 643-52
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Publication
19124715 | J:143503
First Author: Quirion MR
Year: 2009
Journal: J Immunol
Title: Cutting edge: Ikaros is a regulator of Th2 cell differentiation.
Volume: 182
Issue: 2
Pages: 741-5
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Publication
28404635 | J:247791
First Author: Cho S
Year: 2017
Journal: J Immunol
Title: A Novel miR-24-TCF1 Axis in Modulating Effector T Cell Responses.
Volume: 198
Issue: 10
Pages: 3919-3926
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Publication
30315197 | J:267739
First Author: Yamamoto T
Year: 2018
Journal: Nat Commun
Title: DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells.
Volume: 9
Issue: 1
Pages: 4231
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Publication
31851943 | J:353234
First Author: Chen C
Year: 2019
Journal: Cell Rep
Title: Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells.
Volume: 29
Issue: 12
Pages: 4200-4211.e7
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Publication
32868763 | J:300659
First Author: Lee M
Year: 2020
Journal: Nat Commun
Title: Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells.
Volume: 11
Issue: 1
Pages: 4367
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Publication
37294636 | J:338435
First Author: Irie M
Year: 2023
Journal: Cell Rep
Title: Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s.
Volume: 42
Issue: 6
Pages: 112610
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Publication
35583996 | J:326291
First Author: Kopanja D
Year: 2022
Journal: Cancer Res
Title: Transcriptional Repression by FoxM1 Suppresses Tumor Differentiation and Promotes Metastasis of Breast Cancer.
Volume: 82
Issue: 13
Pages: 2458-2471
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Publication
9245507 | J:332297
First Author: Lieuw KH
Year: 1997
Journal: Dev Biol
Title: Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements.
Volume: 188
Issue: 1
Pages: 1-16
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Publication
28659357 | J:250768
First Author: Onodera A
Year: 2017
Journal: J Immunol
Title: Menin Controls the Memory Th2 Cell Function by Maintaining the Epigenetic Integrity of Th2 Cells.
Volume: 199
Issue: 3
Pages: 1153-1162
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Publication
23416424 | J:194468
First Author: Sawant DV
Year: 2013
Journal: Mol Immunol
Title: The Bcl6 target gene microRNA-21 promotes Th2 differentiation by a T cell intrinsic pathway.
Volume: 54
Issue: 3-4
Pages: 435-42
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Publication
36099784 | J:330189
 
First Author: Yokoyama Y
Year: 2022
Journal: Biochem Biophys Res Commun
Title: A20 (Tnfaip3) expressed in CD4+ T cells suppresses Th2 cell-mediated allergic airway inflammation in mice.
Volume: 629
Pages: 47-53
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Publication
19124743 | J:143488
First Author: Ribeiro de Almeida C
Year: 2009
Journal: J Immunol
Title: Critical role for the transcription regulator CCCTC-binding factor in the control of Th2 cytokine expression.
Volume: 182
Issue: 2
Pages: 999-1010
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Publication
19423665 | J:150019
First Author: Dose M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Intrathymic proliferation wave essential for Valpha14+ natural killer T cell development depends on c-Myc.
Volume: 106
Issue: 21
Pages: 8641-6
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Publication
33462454 | J:336889
First Author: Kiner E
Year: 2021
Journal: Nat Immunol
Title: Gut CD4(+) T cell phenotypes are a continuum molded by microbes, not by T(H) archetypes.
Volume: 22
Issue: 2
Pages: 216-228
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Publication
34006643 | J:306304
 
First Author: Ding Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Cell lineage tracing links ERα loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype.
Volume: 118
Issue: 21
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Publication
15102710 | J:91054
First Author: Andl T
Year: 2004
Journal: Development
Title: Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.
Volume: 131
Issue: 10
Pages: 2257-68
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Publication
18802081 | J:141876
First Author: Kurowska-Stolarska M
Year: 2008
Journal: J Immunol
Title: IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4.
Volume: 181
Issue: 7
Pages: 4780-90
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Publication
24323357 | J:297624
First Author: Salimi M
Year: 2013
Journal: J Exp Med
Title: A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis.
Volume: 210
Issue: 13
Pages: 2939-50
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Publication
26178856 | J:235931
 
First Author: Zhang S
Year: 2015
Journal: Sci Rep
Title: Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling.
Volume: 5
Pages: 12113
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Publication
15356142 | J:92741
First Author: Höflinger S
Year: 2004
Journal: J Immunol
Title: Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors.
Volume: 173
Issue: 6
Pages: 3935-44
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Publication
19843690 | J:154675
First Author: Mattes J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease.
Volume: 106
Issue: 44
Pages: 18704-9
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Publication
15470039 | J:93709
First Author: Katsumoto T
Year: 2004
Journal: J Immunol
Title: STAT6-dependent differentiation and production of IL-5 and IL-13 in murine NK2 cells.
Volume: 173
Issue: 8
Pages: 4967-75
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