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Search results 301 to 385 out of 385 for Ttc3

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Type Details Score
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Protein
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 58  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 16  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 43  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: true
Publication
First Author: Suizu F
Year: 2009
Journal: Dev Cell
Title: The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.
Volume: 17
Issue: 6
Pages: 800-10
Interaction Experiment
Description: The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.
Interaction Experiment
Description: The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase.
Publication
First Author: Kim JH
Year: 2019
Journal: Cell Death Dis
Title: TTC3 contributes to TGF-β1-induced epithelial-mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation.
Volume: 10
Issue: 2
Pages: 92
Allele
Name: transgene insertion 28, Edward M Rubin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 4, Edward M Rubin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: transgene insertion 12, Edward M Rubin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: transgenic, mutant strain, coisogenic
Genotype
Symbol: Tg(CEPHY141G6)28Hgc/?
Background: (C57BL/6 x FVB/N)F1
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(CEPHY141G6)4Hgc/?
Background: (C57BL/6 x FVB/N)F1
Zygosity: ot
Has Mutant Allele: true
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant strain, congenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Lepagnol-Bestel AM
Year: 2009
Journal: Hum Mol Genet
Title: DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome.
Volume: 18
Issue: 8
Pages: 1405-14
Genotype
Symbol: Tg(CEPHY152F7)12Hgc/?
Background: (C57BL/6 x FVB/N)F1
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(CEPHY152F7)12Hgc/?
Background: FVB-Tg(CEPHY152F7)12Hgc
Zygosity: ot
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: true
Publication
First Author: Madaule P
Year: 2000
Journal: Microsc Res Tech
Title: Citron, a Rho target that affects contractility during cytokinesis.
Volume: 49
Issue: 2
Pages: 123-6
Publication
First Author: Sarkisian MR
Year: 2002
Journal: J Neurosci
Title: Citron-kinase, a protein essential to cytokinesis in neuronal progenitors, is deleted in the flathead mutant rat.
Volume: 22
Issue: 8
Pages: RC217
Protein Domain
Type: Domain
Description: This domain is found in E3 ubiquitin-protein ligase TTC3 and DZIP3, its function is unknown.TTC3 mediates ubiquitination and degradation of phosphorylated Akt, which seems to be its preferable target [].DZIP3 is able to bind RNA through a Lys-rich region, which enhances its ubiquitination activity. It is suggested that RNA-binding proteins or ribonucleoprotein particles (RNPs) might be physiological targets for this enzyme, which could be important during viral infections as the ubiquitin process also mediates virus budding, especially for those replicating through RNA intermediates [].
Protein Domain
Type: Domain
Description: CRIK (also called citron kinase) is an effector of the small GTPase Rho. It plays an important function during cytokinesis and affects its contractile process []. CRIK-deficient mice show severe ataxia and epilepsy as a result of abnormal cytokinesis and massive apoptosis in neuronal precursors []. A Down syndrome critical region protein TTC3 interacts with CRIK and inhibits CRIK-dependent neuronal differentiation and neurite extension [].CRIK contains a catalytic domain, a central coiled-coil domain, and a C-terminal region containing a Rho-binding domain (RBD), a zinc finger, and a pleckstrin homology (PH) domain, in addition to other motifs.
Publication
First Author: Sebrié C
Year: 2008
Journal: Anat Rec (Hoboken)
Title: Increased dosage of DYRK1A and brain volumetric alterations in a YAC model of partial trisomy 21.
Volume: 291
Issue: 3
Pages: 254-62
Publication
First Author: Kreft SG
Year: 2003
Journal: J Cell Sci
Title: hRUL138, a novel human RNA-binding RING-H2 ubiquitin-protein ligase.
Volume: 116
Issue: Pt 4
Pages: 605-16
Publication
First Author: Smith DJ
Year: 1995
Journal: Genomics
Title: Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2.
Volume: 27
Issue: 3
Pages: 425-34
Publication
First Author: Smith DJ
Year: 1997
Journal: Nat Genet
Title: Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome.
Volume: 16
Issue: 1
Pages: 28-36
Protein
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 382  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1204  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1197  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1179  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1135  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1162  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 776  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 622  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1204  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1979  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1624  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2055  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2028  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2070  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2055  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2013  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112