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Search results 201 to 238 out of 238 for Asl

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0.019s
Type Details Score
Author
Allele  
Name: liver metabolism QTL 11; BTBR
Allele Type: QTL
Allele  
Name: liver metabolism QTL 11; C57BL/6J
Allele Type: QTL
Publication
First Author: Hradilkova K
Year: 2019
Journal: Arthritis Rheumatol
Title: Regulation of Fatty Acid Oxidation by Twist 1 in the Metabolic Adaptation of T Helper Lymphocytes to Chronic Inflammation.
Volume: 71
Issue: 10
Pages: 1756-1765
Publication
First Author: Björkegren JL
Year: 2014
Journal: PLoS Genet
Title: Plasma cholesterol-induced lesion networks activated before regression of early, mature, and advanced atherosclerosis.
Volume: 10
Issue: 2
Pages: e1004201
Publication
First Author: Rossignoli A
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Poliovirus Receptor-Related 2: A Cholesterol-Responsive Gene Affecting Atherosclerosis Development by Modulating Leukocyte Migration.
Volume: 37
Issue: 3
Pages: 534-542
Publication
First Author: Tian Y
Year: 2019
Journal: Nat Commun
Title: ER-residential Nogo-B accelerates NAFLD-associated HCC mediated by metabolic reprogramming of oxLDL lipophagy.
Volume: 10
Issue: 1
Pages: 3391
Publication
First Author: Wang Y
Year: 2022
Journal: Theranostics
Title: MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target.
Volume: 12
Issue: 15
Pages: 6509-6526
Publication
First Author: Wong LJ
Year: 1995
Journal: Genomics
Title: Characterization of the cDNA and the gene encoding murine adenylosuccinate lyase.
Volume: 28
Issue: 2
Pages: 341-3
Protein Domain
Type: Domain
Description: This domain is found at the C terminus of adenylosuccinate lyase (ASL; PurB in Escherichia coli). It has been identified in bacteria, eukaryotes and archaea and is found together with the lyase domain . ASL catalyses the cleavage of succinylaminoimidazole carboxamide ribotide to aminoimidazole carboxamide ribotide and fumarate and the cleavage of adenylosuccinate to adenylate and fumarate [].
Publication
First Author: Shang MM
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Lim domain binding 2: a key driver of transendothelial migration of leukocytes and atherosclerosis.
Volume: 34
Issue: 9
Pages: 2068-77
Publication
First Author: Pasterkamp G
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype.
Volume: 36
Issue: 6
Pages: 1240-6
Publication
First Author: Sun H
Year: 2018
Journal: Nat Commun
Title: An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma.
Volume: 9
Issue: 1
Pages: 5214
Publication
First Author: Zhang Q
Year: 2023
Journal: Sci Adv
Title: Adrenomedullin has a pivotal role in trophoblast differentiation: A promising nanotechnology-based therapeutic target for early-onset preeclampsia.
Volume: 9
Issue: 44
Pages: eadi4777
Protein Domain
Type: Family
Description: Argininosuccinate lyase (ASL or ASAL, ) participates in arginine synthesis in all organisms catalysing the reversible breakdown of argininosuccinate to arginine and fumarate. The reaction is also part of the urea cycle []. The crystal structures of ASLs from several species have been studied, in particular the duck delta1 and delta2 eye lens crystallins, which are inactive and active homologues of ASL, respectively []. ASL is a member of the Lyase class I family, these proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits. In humans, mutations in ASAL result in the autosomal recessive disorder argininosuccinic aciduria [].This entry represents argininosuccinate lyase and includes avian delta crystallins whose biological role is to provide the optically clear cellular protein of the eye lens.
Publication
First Author: Cowley EA
Year: 2000
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Airway surface liquid composition in mice.
Volume: 278
Issue: 6
Pages: L1213-20
Publication
First Author: Stone RL
Year: 1992
Journal: Nat Genet
Title: A mutation in adenylosuccinate lyase associated with mental retardation and autistic features.
Volume: 1
Issue: 1
Pages: 59-63
Publication
First Author: Ferrara CT
Year: 2008
Journal: PLoS Genet
Title: Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.
Volume: 4
Issue: 3
Pages: e1000034
Publication
First Author: Sampaleanu LM
Year: 2002
Journal: J Biol Chem
Title: Mutational analysis of duck delta 2 crystallin and the structure of an inactive mutant with bound substrate provide insight into the enzymatic mechanism of argininosuccinate lyase.
Volume: 277
Issue: 6
Pages: 4166-75
Publication
First Author: Bhaumik P
Year: 2004
Journal: Acta Crystallogr D Biol Crystallogr
Title: Structure determination and refinement at 2.44 A resolution of argininosuccinate lyase from Escherichia coli.
Volume: 60
Issue: Pt 11
Pages: 1964-70
Publication  
First Author: Shen Z
Year: 2018
Journal: Brain Res
Title: Multifaceted assessment of the APP/PS1 mouse model for Alzheimer's disease: Applying MRS, DTI, and ASL.
Volume: 1698
Pages: 114-120
Publication
First Author: Mall MA
Year: 2010
Journal: J Biol Chem
Title: Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice.
Volume: 285
Issue: 35
Pages: 26945-55
Publication
First Author: Grubb BR
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Transgenic hCFTR expression fails to correct β-ENaC mouse lung disease.
Volume: 302
Issue: 2
Pages: L238-47
Publication  
First Author: Garth J
Year: 2019
Journal: Front Med (Lausanne)
Title: The Effects of the Anti-aging Protein Klotho on Mucociliary Clearance.
Volume: 6
Pages: 339
Publication
First Author: Nakagami Y
Year: 2008
Journal: J Immunol
Title: The epithelial anion transporter pendrin is induced by allergy and rhinovirus infection, regulates airway surface liquid, and increases airway reactivity and inflammation in an asthma model.
Volume: 181
Issue: 3
Pages: 2203-10
Publication
First Author: Amery L
Year: 2000
Journal: J Lipid Res
Title: Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans.
Volume: 41
Issue: 11
Pages: 1752-9
Publication
First Author: Boivin-Angèle S
Year: 2000
Journal: Int J Cancer
Title: Ras gene mutations in vinyl chloride-induced liver tumours are carcinogen-specific but vary with cell type and species.
Volume: 85
Issue: 2
Pages: 223-7
Publication
First Author: Haggie PM
Year: 2016
Journal: FASEB J
Title: Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis.
Volume: 30
Issue: 6
Pages: 2187-97
Publication
First Author: Song Y
Year: 2001
Journal: J Gen Physiol
Title: Role of aquaporin water channels in airway fluid transport, humidification, and surface liquid hydration.
Volume: 117
Issue: 6
Pages: 573-82
Publication
First Author: Davis BW
Year: 2015
Journal: Biophys J
Title: Colocalization and Sequential Enzyme Activity in Aqueous Biphasic Systems: Experiments and Modeling.
Volume: 109
Issue: 10
Pages: 2182-94
Publication
First Author: Ariyananda Lde Z
Year: 2009
Journal: Biochemistry
Title: Biochemical and biophysical analysis of five disease-associated human adenylosuccinate lyase mutants.
Volume: 48
Issue: 23
Pages: 5291-302
Protein
Organism: Mus musculus/domesticus
Length: 74  
Fragment?: true
Publication  
First Author: Womack JE
Year: 1989
Journal: Cytogenet Cell Genet
Title: Syntenic mapping of 37 loci in cattle. Chromosomal conservation with mouse and man.
Volume: 51
Pages: 1109 (Abstr.)
Publication  
First Author: Lalley PA
Year: 1981
Journal: Mouse News Lett
Title: Mouse gene mapping in somatic cell hybrids
Volume: 64
Pages: 79-81
Protein
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false