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Search results 301 to 400 out of 1130 for Cdkn1a

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Type Details Score
Publication
16488991 | J:106662
First Author: Yoo LI
Year: 2006
Journal: Cancer Res
Title: Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.
Volume: 66
Issue: 4
Pages: 1929-39
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Publication
22331465 | J:183801
First Author: Zhao H
Year: 2012
Journal: Mol Cell Biol
Title: Loss of cyclin-dependent kinase 2 (CDK2) inhibitory phosphorylation in a CDK2AF knock-in mouse causes misregulation of DNA replication and centrosome duplication.
Volume: 32
Issue: 8
Pages: 1421-32
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Publication
17591974 | J:122824
First Author: Tong C
Year: 2007
Journal: Am J Pathol
Title: c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression.
Volume: 171
Issue: 1
Pages: 297-303
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Publication
26781774 | J:316679
First Author: Zhou Y
Year: 2016
Journal: J Cell Mol Med
Title: MiR-17~92 ablation impairs liver regeneration in an estrogen-dependent manner.
Volume: 20
Issue: 5
Pages: 939-48
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Publication
25919700 | J:242671
First Author: Chen P
Year: 2015
Journal: PLoS One
Title: AMP-18 Targets p21 to Maintain Epithelial Homeostasis.
Volume: 10
Issue: 4
Pages: e0125490
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Publication
34737348 | J:312881
First Author: Ueda S
Year: 2021
Journal: Sci Rep
Title: TGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction.
Volume: 11
Issue: 1
Pages: 21643
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Publication
31112565 | J:275819
First Author: Park KR
Year: 2019
Journal: PLoS One
Title: Loss of parkin reduces lung tumor development by blocking p21 degradation.
Volume: 14
Issue: 5
Pages: e0217037
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Publication
9040936 | J:70785
First Author: Magdaleno SM
Year: 1997
Journal: Cell Growth Differ
Title: Cyclin-dependent kinase inhibitor expression in pulmonary Clara cells transformed with SV40 large T antigen in transgenic mice.
Volume: 8
Issue: 2
Pages: 145-55
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Publication
28204491 | J:242048
First Author: Patzlaff NE
Year: 2017
Journal: Hum Mol Genet
Title: Fragile X related protein 1 (FXR1P) regulates proliferation of adult neural stem cells.
Volume: 26
Issue: 7
Pages: 1340-1352
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Publication
19541625 | J:150832
First Author: Stoyanova T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: DDB2 decides cell fate following DNA damage.
Volume: 106
Issue: 26
Pages: 10690-5
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Publication
15746098 | J:99935
First Author: Shi L
Year: 2005
Journal: J Biol Chem
Title: NF90 regulates cell cycle exit and terminal myogenic differentiation by direct binding to the 3'-untranslated region of MyoD and p21WAF1/CIP1 mRNAs.
Volume: 280
Issue: 19
Pages: 18981-9
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Publication
36868238 | J:334507
First Author: Ji ML
Year: 2023
Journal: Am J Hum Genet
Title: Dynamic chromatin accessibility tuning by the long noncoding RNA ELDR accelerates chondrocyte senescence and osteoarthritis.
Volume: 110
Issue: 4
Pages: 606-624
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Publication
31503005 | J:294783
First Author: Chae U
Year: 2019
Journal: Aging (Albany NY)
Title: Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions.
Volume: 11
Issue: 17
Pages: 7242-7256
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Publication
31427681 | J:284820
First Author: Koyano T
Year: 2019
Journal: Sci Rep
Title: The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis.
Volume: 9
Issue: 1
Pages: 12059
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Publication
11022036 | J:117431
First Author: Azam N
Year: 2001
Journal: J Biol Chem
Title: Interaction of CR6 (GADD45gamma ) with proliferating cell nuclear antigen impedes negative growth control.
Volume: 276
Issue: 4
Pages: 2766-74
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Publication
11718223 | J:73003
First Author: Takesue F
Year: 2001
Journal: J Exp Clin Cancer Res
Title: Development of colonic neoplasms and expressions of p53 and p21 proteins in experimental colitis of mice induced by dextran sulfate sodium.
Volume: 20
Issue: 3
Pages: 413-8
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Publication
10779360 | J:61789
First Author: Smith ML
Year: 2000
Journal: Mol Cell Biol
Title: p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes.
Volume: 20
Issue: 10
Pages: 3705-14
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Publication
11073976 | J:65789
First Author: Bagui TK
Year: 2000
Journal: Mol Cell Biol
Title: Analysis of cyclin D3-cdk4 complexes in fibroblasts expressing and lacking p27(kip1) and p21(cip1).
Volume: 20
Issue: 23
Pages: 8748-57
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Publication
8012956 | J:38869
First Author: Michieli P
Year: 1994
Journal: Cancer Res
Title: Induction of WAF1/CIP1 by a p53-independent pathway.
Volume: 54
Issue: 13
Pages: 3391-5
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Publication
9360984 | J:43981
First Author: Wu RC
Year: 1997
Journal: J Biol Chem
Title: Activation of p53-p21waf1 pathway in response to disruption of cell-matrix interactions.
Volume: 272
Issue: 46
Pages: 29091-8
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Publication
9390024 | J:43463
First Author: Cox LS
Year: 1997
Journal: J Pathol
Title: Multiple pathways control cell growth and transformation: overlapping and independent activities of p53 and p21Cip1/WAF1/Sdi1.
Volume: 183
Issue: 2
Pages: 134-40
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Publication
9488455 | J:45942
First Author: Gorospe M
Year: 1998
Journal: Mol Cell Biol
Title: p53-dependent elevation of p21Waf1 expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system.
Volume: 18
Issue: 3
Pages: 1400-7
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Publication
9572495 | J:47289
First Author: Albrecht JH
Year: 1998
Journal: Oncogene
Title: Involvement of p21 and p27 in the regulation of CDK activity and cell cycle progression in the regenerating liver.
Volume: 16
Issue: 16
Pages: 2141-50
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Publication
10075928 | J:54048
First Author: Cheng M
Year: 1999
Journal: EMBO J
Title: The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts.
Volume: 18
Issue: 6
Pages: 1571-83
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Publication
10200544 | J:52892
First Author: Grilli M
Year: 1999
Journal: Cell Death Differ
Title: Possible role of NF-kappaB and p53 in the glutamate-induced pro-apoptotic neuronal pathway.
Volume: 6
Issue: 1
Pages: 22-7
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Publication
14996726 | J:88831
First Author: Prince S
Year: 2004
Journal: Cancer Res
Title: Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor.
Volume: 64
Issue: 5
Pages: 1669-74
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Publication
15671036 | J:98569
First Author: Yano M
Year: 2005
Journal: J Biol Chem
Title: Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation.
Volume: 280
Issue: 13
Pages: 12690-9
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Publication
16448747 | J:114605
First Author: Arora A
Year: 2006
Journal: Cancer Lett
Title: Regulation of p21/ras protein expression by diallyl sulfide in DMBA induced neoplastic changes in mouse skin.
Volume: 242
Issue: 1
Pages: 28-36
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Publication
19364816 | J:149904
First Author: Hwang CY
Year: 2009
Journal: Mol Cell Biol
Title: Extracellular signal-regulated kinase 2-dependent phosphorylation induces cytoplasmic localization and degradation of p21Cip1.
Volume: 29
Issue: 12
Pages: 3379-89
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Publication
20368355 | J:162582
First Author: Siatecka M
Year: 2010
Journal: Mol Cell Biol
Title: EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation.
Volume: 30
Issue: 11
Pages: 2811-22
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Publication
21596846 | J:174879
First Author: Chagraoui H
Year: 2011
Journal: Blood
Title: SCL-mediated regulation of the cell-cycle regulator p21 is critical for murine megakaryopoiesis.
Volume: 118
Issue: 3
Pages: 723-35
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Publication
22086179 | J:179206
First Author: Choi SH
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Methionine sulfoxide reductase A regulates cell growth through the p53-p21 pathway.
Volume: 416
Issue: 1-2
Pages: 70-5
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Publication
23417300 | J:195988
First Author: Insinga A
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions.
Volume: 110
Issue: 10
Pages: 3931-6
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Publication
27721423 | J:356939
 
First Author: Lopez-Guadamillas E
Year: 2016
Journal: Sci Rep
Title: p21Cip1 plays a critical role in the physiological adaptation to fasting through activation of PPARα.
Volume: 6
Pages: 34542
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Publication
25428126 | J:281899
First Author: Megyesi J
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Increased expression of p21WAF1/CIP1 in kidney proximal tubules mediates fibrosis.
Volume: 308
Issue: 2
Pages: F122-30
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Publication
31881009 | J:297808
First Author: Li B
Year: 2019
Journal: Aging (Albany NY)
Title: Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation.
Volume: 11
Issue: 24
Pages: 12546-12567
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Publication
32686172 | J:304186
First Author: Das S
Year: 2020
Journal: FASEB J
Title: Depletion of cyclic-GMP levels and inhibition of cGMP-dependent protein kinase activate p21Cip1 /p27Kip1 pathways and lead to renal fibrosis and dysfunction.
Volume: 34
Issue: 9
Pages: 11925-11943
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Publication
34083520 | J:333259
First Author: Yuan F
Year: 2021
Journal: Cell Death Dis
Title: Sgpl1 deletion elevates S1P levels, contributing to NPR2 inactivity and p21 expression that block germ cell development.
Volume: 12
Issue: 6
Pages: 574
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Publication
22514271 | J:318916
First Author: Rubinstein JD
Year: 2012
Journal: J Biol Chem
Title: Cyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis.
Volume: 287
Issue: 23
Pages: 19207-15
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Publication
38421300 | J:347871
First Author: Xu Y
Year: 2024
Journal: FASEB J
Title: Kielin/chordin-like protein deficiency aggravates pressure overload-induced cardiac dysfunction and remodeling via P53/P21/CCNB1 signaling in mice.
Volume: 38
Issue: 5
Pages: e23513
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Publication
17694067 | J:125183
First Author: Zhang L
Year: 2007
Journal: Nat Med
Title: The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.
Volume: 13
Issue: 9
Pages: 1060-9
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8084607 | J:20546
First Author: Huppi K
Year: 1994
Journal: Oncogene
Title: Molecular cloning, sequencing, chromosomal localization and expression of mouse p21 (Waf1).
Volume: 9
Issue: 10
Pages: 3017-20
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Publication
20071335 | J:161081
First Author: Li DQ
Year: 2010
Journal: J Biol Chem
Title: Revelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathway.
Volume: 285
Issue: 13
Pages: 10044-52
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Publication
22028794 | J:179766
First Author: Kajiro M
Year: 2011
Journal: PLoS One
Title: The E3 ubiquitin ligase activity of Trip12 is essential for mouse embryogenesis.
Volume: 6
Issue: 10
Pages: e25871
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Publication
12952892 | J:85569
First Author: Shibue T
Year: 2003
Journal: Genes Dev
Title: Integral role of Noxa in p53-mediated apoptotic response.
Volume: 17
Issue: 18
Pages: 2233-8
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16847066 | J:115356
First Author: Griffin SV
Year: 2006
Journal: J Biol Chem
Title: Cyclin I protects podocytes from apoptosis.
Volume: 281
Issue: 38
Pages: 28048-57
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Publication
20935679 | J:168811
First Author: Ahn J
Year: 2011
Journal: Oncogene
Title: Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21(WAF1/CIP1) expression.
Volume: 30
Issue: 4
Pages: 445-56
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Publication
36030260 | J:327972
First Author: Al-Dabet MM
Year: 2022
Journal: Nat Commun
Title: Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression.
Volume: 13
Issue: 1
Pages: 5062
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Publication
26012568 | J:225921
First Author: Yi W
Year: 2015
Journal: Blood
Title: Phosphatase Wip1 controls antigen-independent B-cell development in a p53-dependent manner.
Volume: 126
Issue: 5
Pages: 620-8
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29892060 | J:271583
First Author: Janic A
Year: 2018
Journal: Nat Med
Title: DNA repair processes are critical mediators of p53-dependent tumor suppression.
Volume: 24
Issue: 7
Pages: 947-953
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9398849 | J:76690
First Author: Barlow C
Year: 1997
Journal: Nat Genet
Title: Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways.
Volume: 17
Issue: 4
Pages: 453-6
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9632822 | J:49262
First Author: Xu Y
Year: 1998
Journal: Mol Cell Biol
Title: Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice.
Volume: 18
Issue: 7
Pages: 4385-90
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16023597 | J:99695
First Author: Loeb KR
Year: 2005
Journal: Cancer Cell
Title: A mouse model for cyclin E-dependent genetic instability and tumorigenesis.
Volume: 8
Issue: 1
Pages: 35-47
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21611832 | J:177547
First Author: Kawabata T
Year: 2011
Journal: Mamm Genome
Title: A reduction of licensed origins reveals strain-specific replication dynamics in mice.
Volume: 22
Issue: 9-10
Pages: 506-17
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24958101 | J:224269
First Author: Siu KT
Year: 2014
Journal: Mol Cell Biol
Title: Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation.
Volume: 34
Issue: 17
Pages: 3244-58
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8947040 | J:37025
First Author: Macleod KF
Year: 1996
Journal: EMBO J
Title: Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system.
Volume: 15
Issue: 22
Pages: 6178-88
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9207798 | J:41254
First Author: Hakem R
Year: 1997
Journal: Nat Genet
Title: Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.
Volume: 16
Issue: 3
Pages: 298-302
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38110554 | J:345063
First Author: Brennan MS
Year: 2024
Journal: Cell Death Differ
Title: Combined absence of TRP53 target genes ZMAT3, PUMA and p21 cause a high incidence of cancer in mice.
Volume: 31
Issue: 2
Pages: 159-169
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23665218 | J:198484
First Author: Valente LJ
Year: 2013
Journal: Cell Rep
Title: p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.
Volume: 3
Issue: 5
Pages: 1339-45
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23602569 | J:198507
First Author: Baker DJ
Year: 2013
Journal: Cell Rep
Title: p21 both attenuates and drives senescence and aging in BubR1 progeroid mice.
Volume: 3
Issue: 4
Pages: 1164-74
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23917356 | J:260860
 
First Author: Hoshino A
Year: 2013
Journal: Nat Commun
Title: Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart.
Volume: 4
Pages: 2308
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16251190 | J:106797
First Author: Matheu A
Year: 2005
Journal: J Biol Chem
Title: Regulation of the INK4a/ARF locus by histone deacetylase inhibitors.
Volume: 280
Issue: 51
Pages: 42433-41
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23873265 | J:318818
 
First Author: Li Y
Year: 2013
Journal: Nat Commun
Title: The p53-PUMA axis suppresses iPSC generation.
Volume: 4
Pages: 2174
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26613412 | J:269486
   
First Author: Gao J
Year: 2015
Journal: Elife
Title: The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis.
Volume: 4
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9398851 | J:44388
First Author: Barlow C
Year: 1997
Journal: Nat Genet
Title: Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles.
Volume: 17
Issue: 4
Pages: 462-6
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21385880 | J:205228
First Author: Lu X
Year: 2011
Journal: Mol Cancer Res
Title: Apoptosis is the essential target of selective pressure against p53, whereas loss of additional p53 functions facilitates carcinoma progression.
Volume: 9
Issue: 4
Pages: 430-9
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27065327 | J:237931
First Author: Pant V
Year: 2016
Journal: Oncogene
Title: Distinct downstream targets manifest p53-dependent pathologies in mice.
Volume: 35
Issue: 44
Pages: 5713-5721
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20019247 | J:156707
First Author: Kirsch DG
Year: 2010
Journal: Science
Title: p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis.
Volume: 327
Issue: 5965
Pages: 593-6
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21224054 | J:168235
First Author: Bandi S
Year: 2011
Journal: Am J Pathol
Title: Perturbations in ataxia telangiectasia mutant signaling pathways after drug-induced acute liver failure and their reversal during rescue of animals by cell therapy.
Volume: 178
Issue: 1
Pages: 161-74
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11086062 | J:112128
First Author: Zhang S
Year: 2000
Journal: J Immunol
Title: Cytokine-stimulated T lymphocyte proliferation is regulated by p27Kip1.
Volume: 165
Issue: 11
Pages: 6270-7
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17360438 | J:120056
First Author: Malaterre J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: c-Myb is required for progenitor cell homeostasis in colonic crypts.
Volume: 104
Issue: 10
Pages: 3829-34
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24515438 | J:213623
First Author: Cerqueira A
Year: 2014
Journal: Mol Cell Biol
Title: Genetic characterization of the role of the Cip/Kip family of proteins as cyclin-dependent kinase inhibitors and assembly factors.
Volume: 34
Issue: 8
Pages: 1452-9
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14647411 | J:87536
First Author: Philipp-Staheli J
Year: 2004
Journal: Oncogene
Title: Distinct roles for p53, p27Kip1, and p21Cip1 during tumor development.
Volume: 23
Issue: 4
Pages: 905-13
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Publication
24715455 | J:208851
First Author: Chakkalakal JV
Year: 2014
Journal: Development
Title: Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state.
Volume: 141
Issue: 8
Pages: 1649-59
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Publication
15378017 | J:93856
First Author: Martín-Caballero J
Year: 2004
Journal: Oncogene
Title: Different cooperating effect of p21 or p27 deficiency in combination with INK4a/ARF deletion in mice.
Volume: 23
Issue: 50
Pages: 8231-7
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Publication
23957394 | J:216108
First Author: Vafaie F
Year: 2014
Journal: Aging Cell
Title: Collagenase-resistant collagen promotes mouse aging and vascular cell senescence.
Volume: 13
Issue: 1
Pages: 121-30
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11818069 | J:73917
First Author: Tsai KY
Year: 2002
Journal: Curr Biol
Title: ARF is not required for apoptosis in Rb mutant mouse embryos.
Volume: 12
Issue: 2
Pages: 159-63
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17975001 | J:127141
First Author: Chesnokova V
Year: 2007
Journal: Cancer Res
Title: Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.
Volume: 67
Issue: 21
Pages: 10564-72
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Publication
18981426 | J:143217
First Author: Chesnokova V
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: p21(Cip1) restrains pituitary tumor growth.
Volume: 105
Issue: 45
Pages: 17498-503
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9627115 | J:47889
First Author: Halaban R
Year: 1998
Journal: Oncogene
Title: Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1.
Volume: 16
Issue: 19
Pages: 2489-501
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25656653 | J:260357
First Author: Iglesias-Ara A
Year: 2015
Journal: Cell Death Differ
Title: E2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution.
Volume: 22
Issue: 10
Pages: 1577-89
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Publication
21816922 | J:174680
First Author: Conkrite K
Year: 2011
Journal: Genes Dev
Title: miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma.
Volume: 25
Issue: 16
Pages: 1734-45
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Publication
21368895 | J:234236
 
First Author: Ahmad I
Year: 2011
Journal: Cell Death Dis
Title: Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis.
Volume: 2
Pages: e124
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Publication
15654339 | J:96433
First Author: Johnson TM
Year: 2005
Journal: Nat Genet
Title: The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality.
Volume: 37
Issue: 2
Pages: 145-52
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Publication
12533509 | J:81559
First Author: Cao L
Year: 2003
Journal: Genes Dev
Title: Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform.
Volume: 17
Issue: 2
Pages: 201-13
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