|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 801 to 848 out of 848 for Vangl2

<< First    < Previous  |  Next >    Last >>
0.028s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Sittaramane V
Year: 2013
Journal: Dev Biol
Title: The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function.
Volume: 382
Issue: 2
Pages: 400-12
Publication
First Author: Lei YP
Year: 2010
Journal: N Engl J Med
Title: VANGL2 mutations in human cranial neural-tube defects.
Volume: 362
Issue: 23
Pages: 2232-5
Interaction Experiment
Description: Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Yingzi Yang
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence
Interaction Experiment
Description: Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.
Allele
Name: intergenic site 1; targeted mutation 4, Jeremy Nathans
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, No functional change, Reporter
Strain
Attribute String: mutant stock, targeted mutation
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Yingzi Yang
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Yingzi Yang
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence
Genotype
Symbol: Igs1/Igs1
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 521  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 575  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 393  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 561  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: false
Publication
First Author: Hatakeyama J
Year: 2014
Journal: Endocr Relat Cancer
Title: Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer.
Volume: 21
Issue: 5
Pages: R345-56
Protein Domain
Type: Family
Description: VANGL proteins play important roles in the establishment of planar cell polarity (PCP) []. Vangl2 is required for retinal axon guidance [], kidney-branching morphogenesis and glomerular maturation []. It also plays a role in the orientation of stereociliary bundles in the cochlea and is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process []. It is required for cell surface localization of FZD3 and FZD6 in the inner ear [].
HT Experiment
Series Id: GSE24276
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Ban Y
Year: 2021
Journal: Sci Adv
Title: Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex.
Volume: 7
Issue: 41
Pages: eabh2974
Publication  
First Author: Cheong SS
Year: 2023
Journal: Dis Model Mech
Title: A method for TAT-Cre recombinase-mediated floxed allele modification in ex vivo tissue slices.
Volume: 16
Issue: 11
Publication
First Author: Yang T
Year: 2014
Journal: Cell Tissue Res
Title: Prickle1 is necessary for the caudal migration of murine facial branchiomotor neurons.
Volume: 357
Issue: 3
Pages: 549-61
Publication
First Author: Seo JH
Year: 2011
Journal: Hum Mol Genet
Title: Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans.
Volume: 20
Issue: 22
Pages: 4324-33
Publication
First Author: Treat AC
Year: 2016
Journal: PLoS One
Title: The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization.
Volume: 11
Issue: 4
Pages: e0153144
Publication
First Author: Hayashi K
Year: 2011
Journal: Biol Reprod
Title: WNTs in the neonatal mouse uterus: potential regulation of endometrial gland development.
Volume: 84
Issue: 2
Pages: 308-19
Publication
First Author: Richards T
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling.
Volume: 1865
Issue: 2
Pages: 378-390
Publication
First Author: Goodyear RJ
Year: 2017
Journal: Development
Title: A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane.
Volume: 144
Issue: 21
Pages: 3978-3989
Publication
First Author: Moreno-Fortuny A
Year: 2017
Journal: Biol Open
Title: MCAM contributes to the establishment of cell autonomous polarity in myogenic and chondrogenic differentiation.
Volume: 6
Issue: 11
Pages: 1592-1601
Publication  
First Author: Fernández-Santos B
Year: 2023
Journal: Dis Model Mech
Title: The loop-tail mouse model displays open and closed caudal neural tube defects.
Volume: 16
Issue: 8
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME