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Search results 301 to 333 out of 333 for Sin3b

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Type

Details

Score

Allele

Sin3b<tm1.1Rdp> | MGI:4410334

Name:	transcriptional regulator, SIN3B (yeast); targeted mutation 1.1, Ronald dePinho
Allele Type:	Targeted
Attribute String:	Conditional ready, No functional change

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Allele

Sin3b<tm1Rdp> | MGI:4410333

Name:	transcriptional regulator, SIN3B (yeast); targeted mutation 1, Ronald dePinho
Allele Type:	Targeted
Attribute String:	Conditional ready, No functional change

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Allele

Sin3b<Gt(RRT473)Byg> | MGI:4338584

Name:	transcriptional regulator, SIN3B (yeast); gene trap RRT473, BayGenomics
Allele Type:	Gene trapped

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Allele

Sin3b<em2Cya> | MGI:7586517

Name:	transcriptional regulator, SIN3B (yeast); endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type:	Endonuclease-mediated
Attribute String:	Conditional ready, No functional change

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Allele

Sin3b<tm1.2Rdp> | MGI:4410336

Name:	transcriptional regulator, SIN3B (yeast); targeted mutation 1.2 Ronald dePinho
Allele Type:	Targeted
Attribute String:	Null/knockout

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Interaction Experiment

Jelinic P (2010)

Description:

A novel mammalian complex containing Sin3B mitigates histone acetylation and RNAPII progression within transcribed loci.

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Interaction Experiment

Vega AV (2013)

Description:

Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression.

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Allele

Sin3b<tm1e(EUCOMM)Hmgu> | MGI:4458673

Name:	transcriptional regulator, SIN3B (yeast); targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type:	Targeted
Attribute String:	Null/knockout, Reporter

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Allele

Sin3b<tm1a(EUCOMM)Hmgu> | MGI:4458719

Name:	transcriptional regulator, SIN3B (yeast); targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type:	Targeted
Attribute String:	Conditional ready, Null/knockout, Reporter

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Allele

Sin3b<Gt(CH0195)Wtsi> | MGI:3870590

Name:	transcriptional regulator, SIN3B (yeast); gene trap CH0195, Wellcome Trust Sanger Institute
Allele Type:	Gene trapped

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Strain

MGI:7588959 | C57BL/6J-Sin3b<em2Cya>/Cya

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

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Genotype

Symbol:	Sin3b/Sin3b
Background:	involves: 129 * C57BL/6 * SJL
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Sin3b/Sin3b
Background:	involves: 129 * C57BL/6 * FVB/N * SJL
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Sin3b/Sin3b
Background:	involves: 129 * C57BL/6
Zygosity:	hm
Has Mutant Allele:	true

•

Publication

24077057 | -

First Author:	Vega AV
Year:	2013
Journal:	Sci Rep
Title:	Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression.
Volume:	3

Pages:	2809

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Publication

21041482 | -

First Author:	Jelinic P
Year:	2011
Journal:	Mol Cell Biol
Title:	A novel mammalian complex containing Sin3B mitigates histone acetylation and RNA polymerase II progression within transcribed loci.
Volume:	31
Issue:	1
Pages:	54-62

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Publication

16288918 | -

First Author:	Nomura M
Year:	2005
Journal:	J Mol Biol
Title:	The neural repressor NRSF/REST binds the PAH1 domain of the Sin3 corepressor by using its distinct short hydrophobic helix.
Volume:	354
Issue:	4
Pages:	903-15

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Genotype

Symbol:	Commd10/Commd10<+> Sin3b/Sin3b
Background:	involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca
Zygosity:	cn
Has Mutant Allele:	true

•

Publication

9139820 | -

First Author:	Heinzel T
Year:	1997
Journal:	Nature
Title:	A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.
Volume:	387
Issue:	6628
Pages:	43-8

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Publication

26124119 | -

First Author:	Clark MD
Year:	2015
Journal:	Proc Natl Acad Sci U S A
Title:	Structural insights into the assembly of the histone deacetylase-associated Sin3L/Rpd3L corepressor complex.
Volume:	112
Issue:	28
Pages:	E3669-78

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Publication

8617250 | -

First Author:	Hurlin PJ
Year:	1996
Journal:	EMBO J
Title:	Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.
Volume:	15
Issue:	8
Pages:	2030

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Protein Domain

IPR031693 | Sin3_C

Type:

Domain

Description:

This entry represents a domain found in the C-terminal of the transcriptional repressor Sin3.Budding yeast Sin3 is a component of both the Rpd3S and Rpd3L histone deacetylase complexes []. In mammals there are two Sin3 paraologues, Sin3A and Sin3B. They forms the larger Sin3L/Rpd3L and the smaller Sin3S/Rpd3S complexes, both complexes rely largely on HDAC (histone deacetylase) activity to affect transcriptional repression. Sin3A and Sin3B may partition into the Sin3L/Rpd3L and Sin3S/Rpd3S complexes, respectively [].

•

Protein Domain

IPR013194 | HDAC_interact_dom

Type:

Domain

Description:

This domain is found in the transcriptional repressor Sin3. It forms interactions with histone deacetylases [].Budding yeast Sin3 is a component of both the Rpd3S and Rpd3L histone deacetylase complexes []. In mammals there are two Sin3 paraologues, Sin3A and Sin3B. They forms the larger Sin3L/Rpd3L and the smaller Sin3S/Rpd3S complexes, both complexes rely largely on HDAC (histone deacetylase) activity to affect transcriptional repression. Sin3A and Sin3B may partition into the Sin3L/Rpd3L and Sin3S/Rpd3S complexes, respectively [].

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Publication

16314178 | -

First Author:	Carrozza MJ
Year:	2005
Journal:	Biochim Biophys Acta
Title:	Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.
Volume:	1731
Issue:	2
Pages:	77-87; discussion 75-6

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Publication

19619530 | J:154490

First Author:	Sandoval R
Year:	2009
Journal:	Exp Cell Res
Title:	Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complex.
Volume:	315
Issue:	17
Pages:	2914-20

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Protein

Q3UVS7

Organism:	Mus musculus/domesticus
Length:	311
Fragment?:	true

•

Protein

Q60520

Organism:	Mus musculus/domesticus
Length:	1274
Fragment?:	false

•

Protein

Q3TXW9

Organism:	Mus musculus/domesticus
Length:	1098
Fragment?:	false

•

Publication

12773392 | -

First Author:	Nakayama J
Year:	2003
Journal:	EMBO J
Title:	Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.
Volume:	22
Issue:	11
Pages:	2776-87

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Publication

15368895 | J:92575

First Author:	Okazaki N
Year:	2004
Journal:	DNA Res
Title:	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume:	11
Issue:	3
Pages:	205-18

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Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

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Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

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Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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