Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 144 out of 144 for Senp3

<< First < Previous | Next > Last >>

0.024s

Type

Details

Score

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

•

Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

•

Publication

31914638 | J:299528

First Author:	Shao L
Year:	2020
Journal:	FASEB J
Title:	SUMO1 SUMOylates and SENP3 deSUMOylates NLRP3 to orchestrate the inflammasome activation.
Volume:	34
Issue:	1
Pages:	1497-1515

•

Publication

31141694 | J:300933

First Author:	Nayak A
Year:	2019
Journal:	Cell Rep
Title:	Regulation of SETD7 Methyltransferase by SENP3 Is Crucial for Sarcomere Organization and Cachexia.
Volume:	27
Issue:	9
Pages:	2725-2736.e4

•

Publication

19015314 | -

First Author:	Yun C
Year:	2008
Journal:	J Cell Biol
Title:	Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases.
Volume:	183
Issue:	4
Pages:	589-95

•

Allele

Tnfsf13<tm1Ash> | MGI:3028906

Name:	tumor necrosis factor (ligand) superfamily, member 13; targeted mutation 1, Avi Ashkenazi
Allele Type:	Targeted
Attribute String:	Null/knockout

•

Allele

Tnfsf13<tm1Geha> | MGI:3038886

Name:	tumor necrosis factor (ligand) superfamily, member 13; targeted mutation 1, Raif S Geha
Allele Type:	Targeted
Attribute String:	Null/knockout

•

Strain

MGI:4437830 | B6.129-Tnfsf13<tm1Ash>

Attribute String:

congenic, mutant strain, targeted mutation

•

Publication

14729948 | J:87680

First Author:	Varfolomeev E
Year:	2004
Journal:	Mol Cell Biol
Title:	APRIL-deficient mice have normal immune system development.
Volume:	24
Issue:	3
Pages:	997-1006

•

Publication

25753925 | J:224238

First Author:	Matthes T
Year:	2015
Journal:	Leukemia
Title:	Myelopoiesis dysregulation associated to sustained APRIL production in multiple myeloma-infiltrated bone marrow.
Volume:	29
Issue:	9
Pages:	1901-8

•

Publication

22355399 | J:185324

First Author:	Huard B
Year:	2012
Journal:	PLoS One
Title:	Selective APRIL blockade delays systemic lupus erythematosus in mouse.
Volume:	7
Issue:	2
Pages:	e31837

•

Publication

18471884 | J:136202

First Author:	Hardenberg G
Year:	2008
Journal:	Mol Immunol
Title:	APRIL affects antibody responses and early leukocyte infiltration, but not influenza A viral control.
Volume:	45
Issue:	11
Pages:	3050-8

•

Publication

21642598 | J:176940

First Author:	Matthes T
Year:	2011
Journal:	Blood
Title:	Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow.
Volume:	118
Issue:	7
Pages:	1838-44

•

Publication

18618015 | J:140881

First Author:	Huard B
Year:	2008
Journal:	J Clin Invest
Title:	APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa.
Volume:	118
Issue:	8
Pages:	2887-95

•

Publication

14988498 | J:88910

First Author:	Castigli E
Year:	2004
Journal:	Proc Natl Acad Sci U S A
Title:	Impaired IgA class switching in APRIL-deficient mice.
Volume:	101
Issue:	11
Pages:	3903-8

•

Publication

18322170 | J:132910

First Author:	Benson MJ
Year:	2008
Journal:	J Immunol
Title:	Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL.
Volume:	180
Issue:	6
Pages:	3655-9

•

Publication

30337376 | J:272611

First Author:	Howard L
Year:	2018
Journal:	Development
Title:	TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation.
Volume:	145
Issue:	22

•

Genotype

Symbol:	Tnfsf13/Tnfsf13
Background:	B6.129-Tnfsf13
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Tnfsf13/Tnfsf13
Background:	involves: 129S4/SvJae
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Tnfsf13/Tnfsf13
Background:	involves: 129S4/SvJae * CD-1
Zygosity:	hm
Has Mutant Allele:	true

•

Protein Domain

IPR045577 | SENP3_5_cons_dom

Type:

Domain

Description:

Sentrin/SUMO-specific proteases (SENPs) reversibly regulate the covalent modification of proteins by SUMO. SENP3 and 5 share considerable sequence homology and exhibit similar substrate specificity,as they are active against SUMO-2 and SUMO-3 but less so for SUMO-1. They are more closely related than to SENP1/2. This entry covers the N-terminal region of SENP3/5 containing a conserved domain directly preceding the catalytic domain. This domain is responsible for the subcellular localisation []. SENP3/5 co-localise in the nucleolus and their depletion causes defects in ribosome biogenesis [].

•

Publication

34249943 | J:328508

First Author:	Zhang Y
Year:	2021
Journal:	Front Cell Dev Biol
Title:	SENP3-Mediated PPARγ2 DeSUMOylation in BM-MSCs Potentiates Glucocorticoid-Induced Osteoporosis by Promoting Adipogenesis and Weakening Osteogenesis.
Volume:	9

Pages:	693079

•

Publication

18180376 | J:131537

First Author:	Belnoue E
Year:	2008
Journal:	Blood
Title:	APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells.
Volume:	111
Issue:	5
Pages:	2755-64

•

Publication

28267197 | J:246255

First Author:	Tran NL
Year:	2017
Journal:	Eur J Immunol
Title:	TACI-dependent APRIL signaling maintains autoreactive B cells in a mouse model of systemic lupus erythematosus.
Volume:	47
Issue:	4
Pages:	713-723

•

Publication

28911883 | J:261219

First Author:	McWilliams TG
Year:	2017
Journal:	Exp Neurol
Title:	TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo.
Volume:	298
Issue:	Pt A
Pages:	97-103

•

Publication

31152755 | J:284271

First Author:	Wilson RP
Year:	2019
Journal:	J Invest Dermatol
Title:	IgM Plasma Cells Reside in Healthy Skin and Accumulate with Chronic Inflammation.
Volume:	139
Issue:	12
Pages:	2477-2487

•

Publication

17591783 | -

First Author:	Mikolajczyk J
Year:	2007
Journal:	J Biol Chem
Title:	Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs.
Volume:	282
Issue:	36
Pages:	26217-24

•

Publication

21326211 | -

First Author:	Finkbeiner E
Year:	2011
Journal:	EMBO J
Title:	The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex.
Volume:	30
Issue:	6
Pages:	1067-78

•

Publication

20797632 | -

First Author:	Westman BJ
Year:	2010
Journal:	Mol Cell
Title:	A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58.
Volume:	39
Issue:	4
Pages:	618-31

•

Publication

16738315 | -

First Author:	Di Bacco A
Year:	2006
Journal:	Mol Cell Biol
Title:	The SUMO-specific protease SENP5 is required for cell division.
Volume:	26
Issue:	12
Pages:	4489-98

•

Publication

17341580 | -

First Author:	Zunino R
Year:	2007
Journal:	J Cell Sci
Title:	The SUMO protease SENP5 is required to maintain mitochondrial morphology and function.
Volume:	120
Issue:	Pt 7
Pages:	1178-88

•

Publication

19411255 | -

First Author:	Zunino R
Year:	2009
Journal:	J Biol Chem
Title:	Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis.
Volume:	284
Issue:	26
Pages:	17783-95

•

Publication

25128087 | J:225785

First Author:	Kim EY
Year:	2015
Journal:	J Mol Cell Cardiol
Title:	SENP5, a SUMO isopeptidase, induces apoptosis and cardiomyopathy.
Volume:	78

Pages:	154-64

•

Publication

25984443 | -

First Author:	Federzoni EA
Year:	2015
Journal:	Leuk Res Rep
Title:	Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells.
Volume:	4
Issue:	1
Pages:	32-5

•

Protein Domain

IPR033465 | SENP5

Type:

Family

Description:

SENP5 peptidase (sentrin-specific peptidase 5, MEROPS identifier C48.008) is a deSUMOylating peptidase localized predominantly to the nucleolus. SENP5 releases the tag proteins SUMO-2 and -3 from conjugates, preferentially acting as an isopeptidase rather than an endopeptidase []. Simultaneous depletion of SENP3 and SENP5 results in enhanced SUMOylation of proteins such as RPL37A and GNL2, which are involved in the processing of pre-rRNA [], PELP1 and LAS1L, which are involved in the release of mature ribosomal particles [], and Nop58, which is a component of small nucleolar ribonucleoprotein (snoRNP) and SUMOlyation is required for binding of Nop58 to snoRNA to maintain nucleolar retention []. SENP5 depletion also affects mitotic progression, and cells arrest at the G2/M transition []. SENP5 is also involved in mitochondrial fusion and fission, because SUMOylated dynamin-1-like protein (Drp1), which is a mitochondrial fission factor, is a target for SENP5 []. DeSUMOylation of Drp1 is a contributory factor to cardiomyopathy []. During the G2/M transition stage of mitosis, SENP5 transiently locates to the mitochondrion []. SENP5 is also required for neutrophil differentiation, and the SNP5 gene is repressed in clinical acute myeloid leukemia [].

•

Protein

Q6NXL6

Organism:	Mus musculus/domesticus
Length:	749
Fragment?:	false

•

Protein

F6S6C3

Organism:	Mus musculus/domesticus
Length:	607
Fragment?:	true

•

Protein

F7A4L2

Organism:	Mus musculus/domesticus
Length:	210
Fragment?:	true

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do;jsessionid=844F132D60E0F2A3C8178CBAC0A1DC3B?searchTerm=Senp3&searchBag=&searchOffset=100

MouseMine

Search our database by keyword

Examples

Search results 101 to 144 out of 144 for Senp3

Categories

Hits by Pathway

Hits by Strain

Hits by Category