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Search results 1 to 100 out of 145 for Wnk4

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Category: Publication
Type Details Score
Publication
First Author: Kahle KT
Year: 2003
Journal: Nat Genet
Title: WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion.
Volume: 35
Issue: 4
Pages: 372-6
Publication
First Author: Shibata S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4.
Volume: 110
Issue: 19
Pages: 7838-43
Publication
First Author: Yamauchi K
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Apical localization of renal K channel was not altered in mutant WNK4 transgenic mice.
Volume: 332
Issue: 3
Pages: 750-5
Publication
First Author: Wilson FH
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.
Volume: 100
Issue: 2
Pages: 680-4
Publication
First Author: Yang CL
Year: 2007
Journal: J Clin Invest
Title: The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.
Volume: 117
Issue: 11
Pages: 3403-11
Publication
First Author: Ferdaus MZ
Year: 2019
Journal: Physiol Rep
Title: WNK4 limits distal calcium losses following acute furosemide treatment.
Volume: 7
Issue: 17
Pages: e14195
Publication
First Author: Yang SS
Year: 2010
Journal: Endocrinology
Title: Mechanisms for hypercalciuria in pseudohypoaldosteronism type II-causing WNK4 knock-in mice.
Volume: 151
Issue: 4
Pages: 1829-36
Publication      
First Author: Chen JC
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: WNK4 kinase is a physiological intracellular chloride sensor.
Publication
First Author: Chu PY
Year: 2013
Journal: PLoS One
Title: SPAK deficiency corrects pseudohypoaldosteronism II caused by WNK4 mutation.
Volume: 8
Issue: 9
Pages: e72969
Publication
First Author: Murillo-de-Ozores AR
Year: 2018
Journal: J Biol Chem
Title: C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity.
Volume: 293
Issue: 31
Pages: 12209-12221
Publication
First Author: Mori Y
Year: 2015
Journal: Biochem J
Title: Involvement of selective autophagy mediated by p62/SQSTM1 in KLHL3-dependent WNK4 degradation.
Volume: 472
Issue: 1
Pages: 33-41
Publication
First Author: Kahle KT
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia.
Volume: 101
Issue: 7
Pages: 2064-9
Publication
First Author: Yang YS
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Differential roles of WNK4 in regulation of NCC in vivo.
Volume: 314
Issue: 5
Pages: F999-F1007
Publication
First Author: Zhou B
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: WNK4 inhibits NCC protein expression through MAPK ERK1/2 signaling pathway.
Volume: 302
Issue: 5
Pages: F533-9
Publication  
First Author: Takahashi D
Year: 2017
Journal: EBioMedicine
Title: WNK4 is an Adipogenic Factor and Its Deletion Reduces Diet-Induced Obesity in Mice.
Volume: 18
Pages: 118-127
Publication
First Author: Lalioti MD
Year: 2006
Journal: Nat Genet
Title: Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule.
Volume: 38
Issue: 10
Pages: 1124-32
Publication  
First Author: Takahashi D
Year: 2014
Journal: Biosci Rep
Title: WNK4 is the major WNK positively regulating NCC in the mouse kidney.
Volume: 34
Issue: 3
Publication
First Author: Kasagi Y
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Impaired degradation of medullary WNK4 in the kidneys of KLHL2 knockout mice.
Volume: 487
Issue: 2
Pages: 368-374
Publication
First Author: Ring AM
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.
Volume: 104
Issue: 10
Pages: 4020-4
Publication
First Author: Kahle KT
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension.
Volume: 101
Issue: 41
Pages: 14877-82
Publication
First Author: Susa K
Year: 2017
Journal: Biochem Biophys Res Commun
Title: WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3.
Volume: 491
Issue: 3
Pages: 727-732
Publication
First Author: Susa K
Year: 2014
Journal: Hum Mol Genet
Title: Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.
Volume: 23
Issue: 19
Pages: 5052-60
Publication
First Author: Shibata S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation.
Volume: 111
Issue: 43
Pages: 15556-61
Publication
First Author: Rozansky DJ
Year: 2009
Journal: J Clin Invest
Title: Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway.
Volume: 119
Issue: 9
Pages: 2601-12
Publication
First Author: Subramanya AR
Year: 2009
Journal: J Biol Chem
Title: WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction.
Volume: 284
Issue: 27
Pages: 18471-80
Publication
First Author: Thomson MN
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia.
Volume: 318
Issue: 1
Pages: F216-F228
Publication
First Author: Wakabayashi M
Year: 2013
Journal: Cell Rep
Title: Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension.
Volume: 3
Issue: 3
Pages: 858-68
Publication
First Author: Ohta A
Year: 2009
Journal: Hum Mol Genet
Title: Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure.
Volume: 18
Issue: 20
Pages: 3978-86
Publication
First Author: Mukherjee A
Year: 2021
Journal: Am J Physiol Renal Physiol
Title: Roles of WNK4 and SPAK in K+-mediated dephosphorylation of the NaCl cotransporter.
Volume: 320
Issue: 5
Pages: F719-F733
Publication
First Author: Chiga M
Year: 2011
Journal: J Cell Sci
Title: Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade.
Volume: 124
Issue: Pt 9
Pages: 1391-5
Publication
First Author: Ring AM
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis.
Volume: 104
Issue: 10
Pages: 4025-9
Publication
First Author: Wu P
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule.
Volume: 315
Issue: 2
Pages: F223-F230
Publication
First Author: Wilson FH
Year: 2001
Journal: Science
Title: Human hypertension caused by mutations in WNK kinases.
Volume: 293
Issue: 5532
Pages: 1107-12
Publication
First Author: Yang CL
Year: 2003
Journal: J Clin Invest
Title: WNK kinases regulate thiazide-sensitive Na-Cl cotransport.
Volume: 111
Issue: 7
Pages: 1039-45
Publication
First Author: Shibata S
Year: 2013
Journal: Cell Metab
Title: Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia.
Volume: 18
Issue: 5
Pages: 660-71
Publication
First Author: Terker AS
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: With no lysine kinase 4 modulates sodium potassium 2 chloride cotransporter activity in vivo.
Volume: 315
Issue: 4
Pages: F781-F790
Publication
First Author: Castañeda-Bueno M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation by PKC and PKA regulate the kinase activity and downstream signaling of WNK4.
Volume: 114
Issue: 5
Pages: E879-E886
Publication
First Author: Yang D
Year: 2011
Journal: J Clin Invest
Title: IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.
Volume: 121
Issue: 3
Pages: 956-65
Publication
First Author: Zhang C
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: ENaC and ROMK activity are inhibited in the DCT2/CNT of TgWnk4PHAII mice.
Volume: 312
Issue: 4
Pages: F682-F688
Publication
First Author: Yang SS
Year: 2007
Journal: Cell Metab
Title: Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model.
Volume: 5
Issue: 5
Pages: 331-44
Publication
First Author: Park HW
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature.
Volume: 108
Issue: 26
Pages: 10750-5
Publication
First Author: Chávez-Canales M
Year: 2014
Journal: Hypertension
Title: WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.
Volume: 64
Issue: 5
Pages: 1047-53
Publication
First Author: Dorwart MR
Year: 2007
Journal: J Physiol
Title: SLC26A9 is a Cl(-) channel regulated by the WNK kinases.
Volume: 584
Issue: Pt 1
Pages: 333-45
Publication
First Author: Chiga M
Year: 2008
Journal: Kidney Int
Title: Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone.
Volume: 74
Issue: 11
Pages: 1403-9
Publication
First Author: Castañeda-Bueno M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process.
Volume: 109
Issue: 20
Pages: 7929-34
Publication
First Author: Susa K
Year: 2012
Journal: Clin Exp Nephrol
Title: Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels.
Volume: 16
Issue: 4
Pages: 530-8
Publication
First Author: Lee BH
Year: 2004
Journal: Mol Cell
Title: WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding.
Volume: 15
Issue: 5
Pages: 741-51
Publication
First Author: Melo Z
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Molecular evidence for a role for K(+)-Cl(-) cotransporters in the kidney.
Volume: 305
Issue: 10
Pages: F1402-11
Publication
First Author: Rafael C
Year: 2018
Journal: Sci Rep
Title: Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.
Volume: 8
Issue: 1
Pages: 3249
Publication
First Author: Castañeda-Bueno M
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Modulation of NCC activity by low and high K(+) intake: insights into the signaling pathways involved.
Volume: 306
Issue: 12
Pages: F1507-19
Publication  
First Author: Hung CM
Year: 2020
Journal: Biochem Pharmacol
Title: WNK4-SPAK modulates lipopolysaccharide-induced macrophage activation.
Volume: 171
Pages: 113738
Publication
First Author: Chung WY
Year: 2018
Journal: Mol Cell Biochem
Title: Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2.
Volume: 447
Issue: 1-2
Pages: 165-174
Publication
First Author: Salzler HR
Year: 2007
Journal: Kidney Int
Title: Hypertension and albuminuria in chronic kidney disease mapped to a mouse chromosome 11 locus.
Volume: 72
Issue: 10
Pages: 1226-32
Publication
First Author: Rossier BC
Year: 2013
Journal: FEBS Lett
Title: Genetic dissection of sodium and potassium transport along the aldosterone-sensitive distal nephron: importance in the control of blood pressure and hypertension.
Volume: 587
Issue: 13
Pages: 1929-41
Publication
First Author: Hossain Khan MZ
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Phosphorylation of Na-Cl cotransporter by OSR1 and SPAK kinases regulates its ubiquitination.
Volume: 425
Issue: 2
Pages: 456-61
Publication
First Author: Isobe K
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Development of enzyme-linked immunosorbent assays for urinary thiazide-sensitive Na-Cl cotransporter measurement.
Volume: 305
Issue: 9
Pages: F1374-81
Publication
First Author: McCormick JA
Year: 2014
Journal: J Clin Invest
Title: Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3.
Volume: 124
Issue: 11
Pages: 4723-36
Publication
First Author: Zimdahl H
Year: 2002
Journal: Hypertension
Title: Conserved synteny in rat and mouse for a blood pressure QTL on human chromosome 17.
Volume: 39
Issue: 6
Pages: 1050-2
Publication
First Author: Izadifar A
Year: 2021
Journal: Neuron
Title: Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.
Volume: 109
Issue: 18
Pages: 2864-2883.e8
Publication
First Author: Rinehart J
Year: 2011
Journal: J Biol Chem
Title: WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters.
Volume: 286
Issue: 34
Pages: 30171-80
Publication
First Author: Mayes-Hopfinger L
Year: 2021
Journal: Nat Commun
Title: Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis.
Volume: 12
Issue: 1
Pages: 4546
Publication
First Author: Andrukhova O
Year: 2014
Journal: EMBO J
Title: FGF23 promotes renal calcium reabsorption through the TRPV5 channel.
Volume: 33
Issue: 3
Pages: 229-46
Publication
First Author: Tan Z
Year: 2018
Journal: PLoS Genet
Title: Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.
Volume: 14
Issue: 4
Pages: e1007346
Publication
First Author: Takasato M
Year: 2004
Journal: Mech Dev
Title: Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice.
Volume: 121
Issue: 6
Pages: 547-57
Publication
First Author: Xie Z
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: ZBTB20 is essential for cochlear maturation and hearing in mice.
Volume: 120
Issue: 24
Pages: e2220867120
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication
First Author: Wu G
Year: 2013
Journal: FEBS Lett
Title: Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation.
Volume: 587
Issue: 12
Pages: 1717-22
Publication
First Author: Lin DH
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK).
Volume: 112
Issue: 14
Pages: 4495-500
Publication
First Author: Tatum R
Year: 2007
Journal: FEBS Lett
Title: WNK4 phosphorylates ser(206) of claudin-7 and promotes paracellular Cl(-) permeability.
Volume: 581
Issue: 20
Pages: 3887-91
Publication
First Author: Ohta A
Year: 2013
Journal: Biochem J
Title: The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.
Volume: 451
Issue: 1
Pages: 111-22
Publication
First Author: López-Cayuqueo KI
Year: 2018
Journal: Kidney Int
Title: A mouse model of pseudohypoaldosteronism type II reveals a novel mechanism of renal tubular acidosis.
Volume: 94
Issue: 3
Pages: 514-523
Publication
First Author: Boyden LM
Year: 2012
Journal: Nature
Title: Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities.
Volume: 482
Issue: 7383
Pages: 98-102