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Search results 201 to 281 out of 281 for Upk2

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Type Details Score
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Tg(UPII-SV40T)29Xrw | MGI:2384606
Name: transgene insertion 29, Xue-Ru Wu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(UPII-SV40T)2Xrw | MGI:2384608
Name: transgene insertion 2, Xue-Ru Wu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(UPII-SV40T)9Xrw | MGI:2384609
Name: transgene insertion 9, Xue-Ru Wu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
22496911 | J:209640
First Author: Shen TH
Year: 2012
Journal: PLoS One
Title: A BAC-based transgenic mouse specifically expresses an inducible Cre in the urothelium.
Volume: 7
Issue: 4
Pages: e35243
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Publication
17671122 | J:126722
First Author: Karam JA
Year: 2007
Journal: Clin Cancer Res
Title: Decreased DOC-2/DAB2 expression in urothelial carcinoma of the bladder.
Volume: 13
Issue: 15 Pt 1
Pages: 4400-6
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Publication
16765196 | J:115830
First Author: Johnson AM
Year: 2006
Journal: Urology
Title: Early detection and measurement of urothelial tumors in mice.
Volume: 67
Issue: 6
Pages: 1309-14
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Publication
23908596 | J:322992
First Author: Madka V
Year: 2013
Journal: Neoplasia
Title: p53-stabilizing agent CP-31398 prevents growth and invasion of urothelial cancer of the bladder in transgenic UPII-SV40T mice.
Volume: 15
Issue: 8
Pages: 966-74
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Genotype
Genotype
Symbol: Tg(UPII-SV40T)2Xrw/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(UPII-SV40T)29Xrw/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(UPII-SV40T)9Xrw/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Allele
Tg(Upk2-HRAS*Q61L)12Xrw | MGI:3522718
Name: transgene insertion 12, Xue-Ru Wu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Upk2-HRAS*Q61L)5Xrw | MGI:3522719
Name: transgene insertion 5, Xue-ru Wu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Upk2-cre)6Xrw | MGI:3583893
Name: transgene insertion 6, Xue-Ru Wu
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Upk2-cre)1Rkl | MGI:5014304
Name: transgene insertion 1, Raghu Kalluri
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:5806861 | B6(129)-Tg(Upk2-cre)1Rkl/WghJ
Attribute String: mutant stock, transgenic
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Allele
Tg(Upk2-icre/ERT2)1Ccc | MGI:5568245
Name: transgene insertion 1, Carlos Cordon-Cardo
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Genotype
Genotype
Symbol: Trp53/Trp53 Tg(Upk2-cre)1Rkl/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Upk2-HRAS*Q61L)12Xrw/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Upk2-HRAS*Q61L)5Xrw/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn1a/Cdkn1a Tg(Upk2-cre)6Xrw/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
14737103 | J:88102
First Author: Gao J
Year: 2004
Journal: Oncogene
Title: p53 deficiency provokes urothelial proliferation and synergizes with activated Ha-ras in promoting urothelial tumorigenesis.
Volume: 23
Issue: 3
Pages: 687-96
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Publication
17256055 | J:118042
First Author: Mo L
Year: 2007
Journal: J Clin Invest
Title: Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis.
Volume: 117
Issue: 2
Pages: 314-25
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Publication
32047002 | J:302061
First Author: Kobatake K
Year: 2020
Journal: Clin Cancer Res
Title: Kdm6a Deficiency Activates Inflammatory Pathways, Promotes M2 Macrophage Polarization, and Causes Bladder Cancer in Cooperation with p53 Dysfunction.
Volume: 26
Issue: 8
Pages: 2065-2079
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Publication
30043421 | J:267607
First Author: Foth M
Year: 2018
Journal: J Pathol
Title: FGFR3 mutation increases bladder tumourigenesis by suppressing acute inflammation.
Volume: 246
Issue: 3
Pages: 331-343
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Publication
10416618 | J:56305
First Author: Zhang ZT
Year: 1999
Journal: Cancer Res
Title: Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma.
Volume: 59
Issue: 14
Pages: 3512-7
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Publication
23499463 | J:195340
First Author: Hsu JW
Year: 2013
Journal: Am J Pathol
Title: Decreased tumorigenesis and mortality from bladder cancer in mice lacking urothelial androgen receptor.
Volume: 182
Issue: 5
Pages: 1811-20
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Publication
37544503 | J:342856
First Author: Shuman L
Year: 2023
Journal: Am J Pathol
Title: Urothelium-Specific Expression of Mutationally Activated Pik3ca Initiates Early Lesions of Noninvasive Bladder Cancer.
Volume: 193
Issue: 12
Pages: 2133-2143
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Strain
MGI:5568228 | B6;CBA-Tg(Upk2-icre/ERT2)1Ccc/J
Attribute String: mutant stock, transgenic
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Genotype
Genotype
Symbol: Fgfr3/Fgfr3<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Upk2-cre)1Rkl/?
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
23395910 | J:197843
First Author: Kanasaki K
Year: 2013
Journal: FASEB J
Title: Loss of β1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype.
Volume: 27
Issue: 5
Pages: 1950-61
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Publication
21388952 | J:173505
First Author: Ayala de la Peña F
Year: 2011
Journal: J Biol Chem
Title: Loss of p53 and acquisition of angiogenic microRNA profile are insufficient to facilitate progression of bladder urothelial carcinoma in situ to invasive carcinoma.
Volume: 286
Issue: 23
Pages: 20778-87
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Publication
19951992 | J:155394
First Author: He F
Year: 2009
Journal: Cancer Res
Title: Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis.
Volume: 69
Issue: 24
Pages: 9413-21
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Publication
25277204 | J:310359
First Author: Hsu I
Year: 2014
Journal: Oncotarget
Title: Estrogen receptor alpha prevents bladder cancer via INPP4B inhibited akt pathway in vitro and in vivo.
Volume: 5
Issue: 17
Pages: 7917-35
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Publication
22287562 | J:188975
First Author: Zhou H
Year: 2012
Journal: Carcinogenesis
Title: Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies.
Volume: 33
Issue: 4
Pages: 770-80
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Publication
24760005 | J:215166
First Author: Ayala de la Peña F
Year: 2014
Journal: PLoS One
Title: Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects.
Volume: 9
Issue: 4
Pages: e95888
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Publication
38724885 | J:348247
First Author: Dalghi MG
Year: 2024
Journal: Physiol Rep
Title: Expression and localization of the mechanosensitive/osmosensitive ion channel TMEM63B in the mouse urinary tract.
Volume: 12
Issue: 9
Pages: e16043
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Publication
35283102 | J:324924
 
First Author: Guo C
Year: 2022
Journal: Dev Biol
Title: Arid1a regulates bladder urothelium formation and maintenance.
Volume: 485
Pages: 61-69
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Upk2-cre)6Xrw/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr3/Fgfr3<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr3/Fgfr3<+> Kras/Kras<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Fgfr3/Fgfr3<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Kras/Kras<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn1a/Cdkn1a Ctnnb1/Ctnnb1 Tg(Upk2-cre)6Xrw/?
Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Kras/Kras<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
21368895 | J:234236
 
First Author: Ahmad I
Year: 2011
Journal: Cell Death Dis
Title: Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis.
Volume: 2
Pages: e124
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Publication
29928692 | J:288129
First Author: Kaneko S
Year: 2018
Journal: Sci Adv
Title: X chromosome protects against bladder cancer in females via a KDM6A-dependent epigenetic mechanism.
Volume: 4
Issue: 6
Pages: eaar5598
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Publication
15840768 | J:99613
First Author: Mo L
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: Gene deletion in urothelium by specific expression of Cre recombinase.
Volume: 289
Issue: 3
Pages: F562-8
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Publication
25795707 | J:221118
First Author: He F
Year: 2015
Journal: Cancer Res
Title: Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomas.
Volume: 75
Issue: 10
Pages: 2017-28
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Publication
34903602 | J:321262
First Author: Xia Y
Year: 2022
Journal: Cancer Res
Title: PKM2 Is Essential for Bladder Cancer Growth and Maintenance.
Volume: 82
Issue: 4
Pages: 571-585
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Publication
37318991 | J:360297
First Author: Robilotto GL
Year: 2023
Journal: Am J Physiol Renal Physiol
Title: Optogenetic urothelial cell stimulation induces bladder contractions and pelvic nerve afferent firing.
Volume: 325
Issue: 2
Pages: F150-F163
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Publication
34464353 | J:321399
 
First Author: Dalghi MG
Year: 2021
Journal: JCI Insight
Title: Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception.
Volume: 6
Issue: 19
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Pten/Pten Tg(Upk2-cre)6Xrw/?
Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Pten/Pten Tg(Upk2-cre)6Xrw/?
Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Pten/Pten<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Upk2-cre)6Xrw/? Tg(Upk2-HRAS*Q61L)5Xrw/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Upk2-icre/ERT2)1Ccc/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Upk2-cre)6Xrw/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
21504907 | J:174242
First Author: Ahmad I
Year: 2011
Journal: Dis Model Mech
Title: K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder.
Volume: 4
Issue: 4
Pages: 548-55
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Publication
24519156 | J:210834
First Author: Foth M
Year: 2014
Journal: J Pathol
Title: Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice.
Volume: 233
Issue: 2
Pages: 148-58
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Publication
32339497 | J:293289
First Author: Masuda N
Year: 2020
Journal: Am J Pathol
Title: Trp53 Mutation in Keratin 5 (Krt5)-Expressing Basal Cells Facilitates the Development of Basal Squamous-Like Invasive Bladder Cancer in the Chemical Carcinogenesis of Mouse Bladder.
Volume: 190
Issue: 8
Pages: 1752-1762
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Publication
30670749 | J:275239
First Author: Yee CH
Year: 2019
Journal: Sci Rep
Title: Maintenance of the bladder cancer precursor urothelial hyperplasia requires FOXA1 and persistent expression of oncogenic HRAS.
Volume: 9
Issue: 1
Pages: 270
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Publication
25218638 | J:217711
First Author: Van Batavia J
Year: 2014
Journal: Nat Cell Biol
Title: Bladder cancers arise from distinct urothelial sub-populations.
Volume: 16
Issue: 10
Pages: 982-91, 1-5
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Publication
20818428 | J:164579
First Author: Ahmad I
Year: 2011
Journal: Oncogene
Title: β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.
Volume: 30
Issue: 2
Pages: 178-89
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Publication
28049658 | J:239161
First Author: Guo C
Year: 2017
Journal: Development
Title: Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.
Volume: 144
Issue: 3
Pages: 400-408
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Publication
34470779 | J:311804
First Author: Park S
Year: 2021
Journal: Cancer Res
Title: Novel Mouse Models of Bladder Cancer Identify a Prognostic Signature Associated with Risk of Disease Progression.
Volume: 81
Issue: 20
Pages: 5161-5175
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Publication
23873027 | J:212618
First Author: Chang C
Year: 2014
Journal: Oncogene
Title: Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver.
Volume: 33
Issue: 25
Pages: 3225-34
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Publication
30304685 | J:270845
First Author: Wang J
Year: 2018
Journal: Cell Rep
Title: Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication.
Volume: 25
Issue: 2
Pages: 464-477.e4
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Publication
38517889 | J:348600
First Author: Schwartz L
Year: 2024
Journal: Cell Rep
Title: Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection.
Volume: 43
Issue: 4
Pages: 114007
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Publication
29897287 | J:283631
First Author: Jackson AR
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: The uroplakin plaque promotes renal structural integrity during congenital and acquired urinary tract obstruction.
Volume: 315
Issue: 4
Pages: F1019-F1031
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Publication
33057202 | J:299967
First Author: Marshall KL
Year: 2020
Journal: Nature
Title: PIEZO2 in sensory neurons and urothelial cells coordinates urination.
Volume: 588
Issue: 7837
Pages: 290-295
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Publication
25533675 | J:219292
First Author: Kobayashi T
Year: 2015
Journal: Nat Rev Cancer
Title: Modelling bladder cancer in mice: opportunities and challenges.
Volume: 15
Issue: 1
Pages: 42-54
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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