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Search results 3001 to 3100 out of 3295 for Kras

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Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Kras/Kras<+> Raf1/Raf1
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Publication
30905671 | J:275676
First Author: Sullivan MR
Year: 2019
Journal: Cell Metab
Title: Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting.
Volume: 29
Issue: 6
Pages: 1410-1421.e4
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Publication
19412424 | J:265595
First Author: Hambardzumyan D
Year: 2009
Journal: Transl Oncol
Title: Modeling Adult Gliomas Using RCAS/t-va Technology.
Volume: 2
Issue: 2
Pages: 89-95
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Publication
29949764 | J:271084
First Author: Ozawa T
Year: 2018
Journal: Cell Rep
Title: A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.
Volume: 23
Issue: 13
Pages: 3787-3797
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Publication
15967113 | J:100163
First Author: Hu X
Year: 2005
Journal: Neoplasia
Title: mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma.
Volume: 7
Issue: 4
Pages: 356-68
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Publication
25117714 | J:214594
First Author: Ozawa T
Year: 2014
Journal: Cancer Cell
Title: Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma.
Volume: 26
Issue: 2
Pages: 288-300
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Publication
28658205 | J:252222
First Author: Zabala-Letona A
Year: 2017
Journal: Nature
Title: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.
Volume: 547
Issue: 7661
Pages: 109-113
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Publication
29057879 | J:250117
First Author: Hieronymus H
Year: 2017
Journal: Nat Commun
Title: Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis.
Volume: 8
Issue: 1
Pages: 1081
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Publication
26037915 | J:225604
First Author: Resnick-Silverman L
Year: 2015
Journal: Cancer Discov
Title: Two Faces of SIVA.
Volume: 5
Issue: 6
Pages: 581-3
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Publication
35982178 | J:330821
First Author: Yuan M
Year: 2022
Journal: Nat Cancer
Title: Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth.
Volume: 3
Issue: 8
Pages: 945-960
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Genotype
Genotype
Symbol: Cdk4/Cdk4<+> Kras/Kras<+> Tg(CMV-cre)1Cgn/?
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(CMV-cre/ERT)1Ipc/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Mapk14/Mapk14<+> Polr2a/Polr2a<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdk4/Cdk4 Kras/Kras Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdk6/Cdk6 Kras/Kras<+> Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdk2/Cdk2 Kras/Kras<+> Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdk2/Cdk2 Kras/Kras Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras Tg(Cela1-tTA)#Eps/? Tg(tetO-cre)3Jig/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Mapk1/Mapk1 Mapk3/Mapk3
Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Map2k1/Map2k1 Map2k2/Map2k2
Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf Kras/Kras<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf Kras/Kras<+> Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Polr2a/Polr2a Raf1/Raf1
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ptf1a/Ptf1a<+> Tg(tetO-Kras*G12D)#Rdp/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Pdx1/Pdx1<+> Trp53/Trp53<+>
Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * Black Swiss * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Pdx1/Pdx1<+> Trp53/Trp53
Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * Black Swiss * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
27748748 | J:240751
First Author: International Cancer Genome Consortium PedBrain Tumor Project.
Year: 2016
Journal: Nat Med
Title: Recurrent MET fusion genes represent a drug target in pediatric glioblastoma.
Volume: 22
Issue: 11
Pages: 1314-1320
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Publication
28394259 | J:244425
First Author: Huang Y
Year: 2017
Journal: J Clin Invest
Title: A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma.
Volume: 127
Issue: 5
Pages: 1826-1838
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Publication
27935821 | J:293441
First Author: Yang Z
Year: 2017
Journal: Dis Model Mech
Title: Stromal hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer.
Volume: 10
Issue: 1
Pages: 39-52
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Publication
20826752 | J:164283
First Author: Rolf J
Year: 2010
Journal: J Immunol
Title: Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction.
Volume: 185
Issue: 7
Pages: 4042-52
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Publication
28875501 | J:256597
First Author: Yang CS
Year: 2017
Journal: Prostate
Title: The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression.
Volume: 77
Issue: 15
Pages: 1452-1467
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Publication
28262675 | J:244308
 
First Author: Lefebure M
Year: 2017
Journal: Nat Commun
Title: Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.
Volume: 8
Pages: 14581
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Publication
20814421 | J:164580
First Author: Morris JP 4th
Year: 2010
Journal: Nat Rev Cancer
Title: KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.
Volume: 10
Issue: 10
Pages: 683-95
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Publication
23658296 | J:200542
First Author: Chen R
Year: 2013
Journal: Cancer Discov
Title: Two is better than one: combining IGF1R and MEK blockade as a promising novel treatment strategy against KRAS-mutant lung cancer.
Volume: 3
Issue: 5
Pages: 491-3
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Publication
32289276 | J:287286
First Author: Drosten M
Year: 2020
Journal: Cancer Cell
Title: Targeting the MAPK Pathway in KRAS-Driven Tumors.
Volume: 37
Issue: 4
Pages: 543-550
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Protein Coding Gene
MGI:1915113 | Slc25a11
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0016643 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018607 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018544 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018360 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018998 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018442 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018432 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018512 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017689 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017969 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017774 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017479 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
30686754 | J:294965
 
First Author: Lee JS
Year: 2019
Journal: EBioMedicine
Title: Loss of SLC25A11 causes suppression of NSCLC and melanoma tumor formation.
Volume: 40
Pages: 184-197
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Publication
4687397 | J:327631
First Author: Sluse FE
Year: 1973
Journal: Eur J Biochem
Title: Mechanism of the exchanges catalysed by the oxoglutarate translocator of rat-heart mitochondria. Kinetics of the external-product inhibition.
Volume: 32
Issue: 2
Pages: 283-91
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Publication
35507647 | J:327478
First Author: Yuan Y
Year: 2022
Journal: Sci Adv
Title: α-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling.
Volume: 8
Issue: 18
Pages: eabn2879
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GXD Expression
GXD Expression
Probe: MGI:971801
Assay Type: RNA in situ
Annotation Date: 2011-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Non-Uniform
Stage: TS23
Assay Id: MGI:4888665
Age: embryonic day 14.5
Image: Table S1
Note: Expression is ubiquitous with a pattern.
Specimen Label: Table S1
Detected: true
Specimen Num: 1
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Strain
MGI:7610043 | B6;129-Gt(ROSA)26Sor<tm2(CAG-rtTA3,-mKate2)Slowe> Kras<tm4Tyj> Trp53<tm1Brn> Col1a1<tm3(tetO-GFP/RNAi:Kras247)Ttam>/TtamJ
Attribute String: targeted mutation, mutant stock
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Strain
MGI:7610041 | B6;129-Gt(ROSA)26Sor<tm2(CAG-rtTA3,-mKate2)Slowe> Kras<tm4Tyj> Trp53<tm1Brn> Col1a1<tm2(tetO-GFP/RNAi:Kras462)Ttam>/TtamJ
Attribute String: targeted mutation, mutant stock
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Genotype
Genotype
Symbol: Kras/Kras<+> Mapk14/Mapk14 Polr2a/Polr2a<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Kras/Kras<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdk4/Cdk4 Kras/Kras Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Trp53/Trp53<+> Tg(Cela1-tTA)#Eps/? Tg(tetO-cre)3Jig/?
Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf Kras/Kras<+> Polr2a/Polr2a Raf1/Raf1
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ptf1a/Ptf1a<+> Tg(tetO-Kras*G12D)#Rdp/? Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ptf1a/Ptf1a<+> Tg(tetO-Kras*G12D)#Rdp/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
29445180 | J:257943
First Author: Marazioti A
Year: 2018
Journal: Nat Commun
Title: Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.
Volume: 9
Issue: 1
Pages: 672
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Publication
18344980 | J:133950
First Author: Lim KH
Year: 2008
Journal: Nature
Title: Tumour maintenance is mediated by eNOS.
Volume: 452
Issue: 7187
Pages: 646-9
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Publication
23358651 | J:198243
First Author: Konstantinidou G
Year: 2013
Journal: Cancer Discov
Title: RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas.
Volume: 3
Issue: 4
Pages: 444-57
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Publication
28249168 | J:256196
First Author: Rajbhandari N
Year: 2017
Journal: Cell Rep
Title: Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers.
Volume: 18
Issue: 9
Pages: 2243-2255
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Publication
37172086 | J:335643
First Author: Bu W
Year: 2023
Journal: Sci Adv
Title: Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice.
Volume: 9
Issue: 19
Pages: eade0059
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Publication
30452622 | J:277563
First Author: Ni H
Year: 2019
Journal: Carcinogenesis
Title: ErbB4 acts as a suppressor in colitis and its associated carcinoma by negatively regulating cholesterol metabolism.
Volume: 40
Issue: 5
Pages: 680-686
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Publication
37169967 | J:335562
     
First Author: Ely ZA
Year: 2023
Journal: Nat Biotechnol
Title: A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
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Publication
34193976 | J:317339
First Author: Thomas KR
Year: 2022
Journal: Leukemia
Title: Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice.
Volume: 36
Issue: 1
Pages: 42-57
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Publication
27270400 | J:244991
First Author: Akula MK
Year: 2016
Journal: Nat Immunol
Title: Control of the innate immune response by the mevalonate pathway.
Volume: 17
Issue: 8
Pages: 922-9
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Publication
31140976 | J:277408
   
First Author: Spella M
Year: 2019
Journal: Elife
Title: Club cells form lung adenocarcinomas and maintain the alveoli of adult mice.
Volume: 8
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Publication
27292643 | J:238300
First Author: Rowald K
Year: 2016
Journal: Cell Rep
Title: Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth.
Volume: 15
Issue: 12
Pages: 2679-91
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Publication
26657862 | J:230034
First Author: Edmonds MD
Year: 2016
Journal: J Clin Invest
Title: MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.
Volume: 126
Issue: 1
Pages: 349-64
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Publication
20173739 | J:158125
First Author: Sotillo R
Year: 2010
Journal: Nature
Title: Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal.
Volume: 464
Issue: 7287
Pages: 436-40
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Publication
28980940 | J:258217
   
First Author: Zhang Y
Year: 2017
Journal: Elife
Title: Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice.
Volume: 6
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Publication
23825589 | J:203456
First Author: González-Sánchez E
Year: 2013
Journal: PLoS One
Title: Lkb1 loss promotes tumor progression of BRAF(V600E)-induced lung adenomas.
Volume: 8
Issue: 6
Pages: e66933
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Publication
16166301 | J:101615
First Author: Holmen SL
Year: 2005
Journal: Cancer Res
Title: Essential role for Ras signaling in glioblastoma maintenance.
Volume: 65
Issue: 18
Pages: 8250-5
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Publication
20444198 | J:229152
First Author: VanBrocklin MW
Year: 2010
Journal: Pigment Cell Melanoma Res
Title: Targeted delivery of NRASQ61R and Cre-recombinase to post-natal melanocytes induces melanoma in Ink4a/Arflox/lox mice.
Volume: 23
Issue: 4
Pages: 531-41
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Publication
36641749 | J:332854
First Author: Kim YE
Year: 2023
Journal: Cell Rep
Title: Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway.
Volume: 42
Issue: 1
Pages: 112003
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Publication
34652874 | J:330726
First Author: Morishita M
Year: 2021
Journal: Genes Cells
Title: Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF-κB signaling.
Volume: 26
Issue: 12
Pages: 999-1013
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Publication
22144181 | J:181746
First Author: Xu J
Year: 2012
Journal: Blood
Title: Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras.
Volume: 119
Issue: 4
Pages: 1032-5
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Publication
23512660 | J:195287
First Author: Wong CE
Year: 2013
Journal: Genes Dev
Title: Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression.
Volume: 27
Issue: 6
Pages: 670-82
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Publication
25593307 | J:218233
First Author: Wang L
Year: 2015
Journal: Genes Dev
Title: ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis.
Volume: 29
Issue: 2
Pages: 171-83
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Publication
26132860 | J:225835
 
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