Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:6191620 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-10-17 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3801322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:6202633 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
1 E14.5 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6191620 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-10-17 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3801323 |
|
Stage: |
TS23 |
Assay Id: |
MGI:6202633 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
1 E15.5 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6191620 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-10-17 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3801324 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6202633 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
1 E16.5 |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6191620 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-10-17 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3801325 |
|
Stage: |
TS25 |
Assay Id: |
MGI:6202633 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
1 E17.5 |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lane PW |
Year: |
1975 |
Journal: |
Mouse News Lett |
Title: |
Chromosome 12. |
Volume: |
53 |
|
Pages: |
35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Turner CT |
Year: |
2021 |
Journal: |
J Invest Dermatol |
Title: |
Granzyme B Contributes to Barrier Dysfunction in Oxazolone-Induced Skin Inflammation through E-Cadherin and FLG Cleavage. |
Volume: |
141 |
Issue: |
1 |
Pages: |
36-47 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456161 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-09-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3735528 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6456583 |
Age: |
postnatal adult |
Image: |
1A KRT76 |
Note: |
Highest expression in granular layer overlapping with Flg expression. |
Specimen Label: |
1A KRT76 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Allele |
Name: |
filaggrin; flaky tail |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Flg/Flg |
Background: |
STOCK a/a Tmem79 Flg/J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
731
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
820
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
822
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
832
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
733
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
733
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Markus Schubert |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Epitope tag, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
Publication |
First Author: |
Zemva J |
Year: |
2013 |
Journal: |
Age (Dordr) |
Title: |
Neuronal overexpression of insulin receptor substrate 2 leads to increased fat mass, insulin resistance, and glucose intolerance during aging. |
Volume: |
35 |
Issue: |
5 |
Pages: |
1881-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Avivi A |
Year: |
1991 |
Journal: |
Oncogene |
Title: |
Flg-2, a new member of the family of fibroblast growth factor receptors. |
Volume: |
6 |
Issue: |
6 |
Pages: |
1089-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruta M |
Year: |
1989 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Receptor for acidic fibroblast growth factor is related to the tyrosine kinase encoded by the fms-like gene (FLG). |
Volume: |
86 |
Issue: |
22 |
Pages: |
8722-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Raz V |
Year: |
1991 |
Journal: |
Oncogene |
Title: |
PCR-based identification of new receptors: molecular cloning of a receptor for fibroblast growth factors. |
Volume: |
6 |
Issue: |
5 |
Pages: |
753-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mansukhani A |
Year: |
1992 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. |
Volume: |
89 |
Issue: |
8 |
Pages: |
3305-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yeh CY |
Year: |
2023 |
Journal: |
J Invest Dermatol |
Title: |
PD-L1 Enhanced by cis-Urocanic Acid on Langerhans Cells Inhibits Vγ4(+) γδT17 Cells in Psoriatic Skin Inflammation. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Venesio T |
Year: |
1992 |
Journal: |
Cell Growth Differ |
Title: |
The int-2 gene product acts as a growth factor and substitutes for basic fibroblast growth factor in promoting the differentiation of a normal mouse mammary epithelial cell line. |
Volume: |
3 |
Issue: |
1 |
Pages: |
63-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peters KG |
Year: |
1992 |
Journal: |
Development |
Title: |
Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. |
Volume: |
114 |
Issue: |
1 |
Pages: |
233-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Knol EF |
Year: |
2016 |
Journal: |
Eur J Immunol |
Title: |
Atopic dermatitis: A tale of two distinct pathomechanisms that make you itch. |
Volume: |
46 |
Issue: |
11 |
Pages: |
2512-2515 |
|
•
•
•
•
•
|
Publication |
First Author: |
Noh JY |
Year: |
2019 |
Journal: |
J Invest Dermatol |
Title: |
ZAG Regulates the Skin Barrier and Immunity in Atopic Dermatitis. |
Volume: |
139 |
Issue: |
8 |
Pages: |
1648-1657.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Usui K |
Year: |
2023 |
Journal: |
J Allergy Clin Immunol |
Title: |
TRPV1-positive sensory nerves and neuropeptides are involved in epidermal barrier repair after tape stripping in mice. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yasuda Y |
Year: |
1992 |
Journal: |
Dev Biol |
Title: |
Induction of avascular yolk sac due to reduction of basic fibroblast growth factor by retinoic acid in mice. |
Volume: |
150 |
Issue: |
2 |
Pages: |
397-413 |
|
•
•
•
•
•
|