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Search results 501 to 600 out of 803 for Rptor

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Type Details Score
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Kumar A
Year: 2008
Journal: Mol Cell Biol
Title: Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity.
Volume: 28
Issue: 1
Pages: 61-70
Publication
First Author: Mazei-Robison MS
Year: 2011
Journal: Neuron
Title: Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons.
Volume: 72
Issue: 6
Pages: 977-90
Publication
First Author: Zhang Y
Year: 2014
Journal: PLoS One
Title: Rictor is required for early B cell development in bone marrow.
Volume: 9
Issue: 8
Pages: e103970
Publication
First Author: Fang Y
Year: 2017
Journal: Leukemia
Title: Rictor has a pivotal role in maintaining quiescence as well as stemness of leukemia stem cells in MLL-driven leukemia.
Volume: 31
Issue: 2
Pages: 414-422
Publication
First Author: Dadalko OI
Year: 2015
Journal: J Neurosci
Title: mTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission.
Volume: 35
Issue: 23
Pages: 8843-54
Publication
First Author: Thomanetz V
Year: 2013
Journal: J Cell Biol
Title: Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology.
Volume: 201
Issue: 2
Pages: 293-308
Publication
First Author: Wang Y
Year: 2022
Journal: Clin Cancer Res
Title: Cholesterol-Lowering Intervention Decreases mTOR Complex 2 Signaling and Enhances Antitumor Immunity.
Volume: 28
Issue: 2
Pages: 414-424
Publication
First Author: Bhattacharya I
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Rictor in perivascular adipose tissue controls vascular function by regulating inflammatory molecule expression.
Volume: 33
Issue: 9
Pages: 2105-11
Publication
First Author: Drägert K
Year: 2015
Journal: Hypertension
Title: Deletion of Rictor in brain and fat alters peripheral clock gene expression and increases blood pressure.
Volume: 66
Issue: 2
Pages: 332-9
Publication
First Author: Prevot N
Year: 2015
Journal: J Immunol
Title: Mammalian target of rapamycin complex 2 regulates invariant NKT cell development and function independent of promyelocytic leukemia zinc-finger.
Volume: 194
Issue: 1
Pages: 223-30
Publication
First Author: Xie Y
Year: 2017
Journal: Biochim Biophys Acta
Title: The mTORC2/PKC pathway sustains compensatory insulin secretion of pancreatic β cells in response to metabolic stress.
Volume: 1861
Issue: 8
Pages: 2039-2047
Publication  
First Author: Liu DM
Year: 2016
Journal: Bone
Title: Rictor/mTORC2 loss in osteoblasts impairs bone mass and strength.
Volume: 90
Pages: 50-8
Publication
First Author: Castro-Martinez F
Year: 2021
Journal: Am J Pathol
Title: Rictor/Mammalian Target of Rapamycin Complex 2 Signaling Protects Colonocytes from Apoptosis and Prevents Epithelial Barrier Breakdown.
Volume: 191
Issue: 9
Pages: 1537-1549
Publication  
First Author: Sun W
Year: 2016
Journal: Bone
Title: Rictor is required for optimal bone accrual in response to anti-sclerostin therapy in the mouse.
Volume: 85
Pages: 1-8
Publication
First Author: Li J
Year: 2014
Journal: Kidney Int
Title: Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury.
Volume: 86
Issue: 1
Pages: 86-102
Publication
First Author: Bai S
Year: 2018
Journal: Mol Hum Reprod
Title: A germline-specific role for the mTORC2 component Rictor in maintaining spermatogonial differentiation and intercellular adhesion in mouse testis.
Volume: 24
Issue: 5
Pages: 244-259
Publication
First Author: Huang W
Year: 2013
Journal: Nat Neurosci
Title: mTORC2 controls actin polymerization required for consolidation of long-term memory.
Volume: 16
Issue: 4
Pages: 441-8
Publication
First Author: Yu D
Year: 2019
Journal: Cell Rep
Title: Calorie-Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension.
Volume: 29
Issue: 1
Pages: 236-248.e3
Publication
First Author: Ren J
Year: 2017
Journal: J Pathol
Title: Rictor/mammalian target of rapamycin complex 2 promotes macrophage activation and kidney fibrosis.
Volume: 242
Issue: 4
Pages: 488-499
Publication
First Author: Morrison Joly M
Year: 2016
Journal: Cancer Res
Title: Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers.
Volume: 76
Issue: 16
Pages: 4752-64
Publication  
First Author: Martinez N
Year: 2019
Journal: EBioMedicine
Title: mTORC2/Akt activation in adipocytes is required for adipose tissue inflammation in tuberculosis.
Volume: 45
Pages: 314-327
Publication
First Author: Dahl KD
Year: 2023
Journal: J Neurosci
Title: mTORC2 Loss in Oligodendrocyte Progenitor Cells Results in Regional Hypomyelination in the Central Nervous System.
Volume: 43
Issue: 4
Pages: 540-558
Allele
Name: regulatory associated protein of MTOR, complex 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Yuan M
Year: 2012
Journal: J Biol Chem
Title: Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2.
Volume: 287
Issue: 35
Pages: 29579-88
Publication
First Author: Lamming DW
Year: 2014
Journal: FASEB J
Title: Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2).
Volume: 28
Issue: 1
Pages: 300-15
Publication
First Author: Grahammer F
Year: 2016
Journal: J Clin Invest
Title: mTORC2 critically regulates renal potassium handling.
Volume: 126
Issue: 5
Pages: 1773-82
Publication
First Author: Suryawanshi RK
Year: 2021
Journal: Nat Commun
Title: mTORC2 confers neuroprotection and potentiates immunity during virus infection.
Volume: 12
Issue: 1
Pages: 6020
Publication  
First Author: Katholnig K
Year: 2019
Journal: JCI Insight
Title: Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis.
Volume: 4
Issue: 20
Publication
First Author: Oh MH
Year: 2017
Journal: Cell Rep
Title: mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages.
Volume: 20
Issue: 10
Pages: 2439-2454
Publication
First Author: Tassone B
Year: 2017
Journal: Cell Death Differ
Title: Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis.
Volume: 24
Issue: 4
Pages: 731-746
Publication
First Author: Hua C
Year: 2014
Journal: Exp Hematol
Title: Rictor/mammalian target of rapamycin 2 regulates the development of Notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3.
Volume: 42
Issue: 12
Pages: 1031-40.e1-4
Publication
First Author: Zhang L
Year: 2016
Journal: Cell Rep
Title: Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner.
Volume: 14
Issue: 5
Pages: 1206-1217
Publication
First Author: Ding X
Year: 2020
Journal: J Allergy Clin Immunol
Title: Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation.
Volume: 145
Issue: 1
Pages: 283-300.e8
Publication
First Author: Zhang Y
Year: 2021
Journal: FASEB J
Title: Rictor/mTORC2 is involved in endometrial receptivity by regulating epithelial remodeling.
Volume: 35
Issue: 7
Pages: e21731
Publication
First Author: Kocalis HE
Year: 2014
Journal: Mol Metab
Title: Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis.
Volume: 3
Issue: 4
Pages: 394-407
Publication
First Author: Frei IC
Year: 2023
Journal: Am J Physiol Endocrinol Metab
Title: Hepatic mTORC2 compensates for loss of adipose mTORC2 in mediating energy storage and glucose homeostasis.
Volume: 324
Issue: 6
Pages: E589-E598
Publication
First Author: Shimobayashi M
Year: 2018
Journal: J Clin Invest
Title: Insulin resistance causes inflammation in adipose tissue.
Volume: 128
Issue: 4
Pages: 1538-1550
Publication
First Author: Van de Velde LA
Year: 2016
Journal: J Biol Chem
Title: Proliferating Helper T Cells Require Rictor/mTORC2 Complex to Integrate Signals from Limiting Environmental Amino Acids.
Volume: 291
Issue: 50
Pages: 25815-25822
Publication  
First Author: Kaska S
Year: 2017
Journal: Neuropharmacology
Title: Deletion of Rictor in catecholaminergic neurons alters locomotor activity and ingestive behavior.
Volume: 117
Pages: 158-170
Publication
First Author: Dibble CC
Year: 2009
Journal: Mol Cell Biol
Title: Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1.
Volume: 29
Issue: 21
Pages: 5657-70
Publication  
First Author: Bhat N
Year: 2022
Journal: J Clin Invest
Title: Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice.
Volume: 132
Issue: 3
Publication
First Author: Ruiz A
Year: 2018
Journal: Sci Rep
Title: Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance.
Volume: 8
Issue: 1
Pages: 636
Publication
First Author: Zou Z
Year: 2015
Journal: J Cell Biol
Title: mTORC2 promotes cell survival through c-Myc-dependent up-regulation of E2F1.
Volume: 211
Issue: 1
Pages: 105-22
Publication
First Author: Wang Y
Year: 2022
Journal: Nat Immunol
Title: The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis.
Volume: 23
Issue: 2
Pages: 303-317
Publication
First Author: Cortada M
Year: 2023
Journal: iScience
Title: mTORC2 regulates auditory hair cell structure and function.
Volume: 26
Issue: 9
Pages: 107687
Publication
First Author: Siuta MA
Year: 2010
Journal: PLoS Biol
Title: Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice.
Volume: 8
Issue: 6
Pages: e1000393
Publication
First Author: Cybulski N
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: mTOR complex 2 in adipose tissue negatively controls whole-body growth.
Volume: 106
Issue: 24
Pages: 9902-7
Publication
First Author: Albert V
Year: 2016
Journal: EMBO Mol Med
Title: mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue.
Volume: 8
Issue: 3
Pages: 232-46
Publication
First Author: Kumar A
Year: 2010
Journal: Diabetes
Title: Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.
Volume: 59
Issue: 6
Pages: 1397-406
Publication
First Author: Chen J
Year: 2015
Journal: J Bone Miner Res
Title: mTORC2 signaling promotes skeletal growth and bone formation in mice.
Volume: 30
Issue: 2
Pages: 369-78
Publication  
First Author: Aimi F
Year: 2015
Journal: Sci Rep
Title: Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult.
Volume: 5
Pages: 17705
Publication
First Author: Liang Z
Year: 2018
Journal: Autophagy
Title: MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Volume: 14
Issue: 3
Pages: 505-517
Publication
First Author: Lee K
Year: 2012
Journal: J Exp Med
Title: Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia.
Volume: 209
Issue: 4
Pages: 713-28
Publication
First Author: Lee K
Year: 2010
Journal: Immunity
Title: Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.
Volume: 32
Issue: 6
Pages: 743-53
Publication      
First Author: Castro E
Year: 2021
Journal: Am J Physiol Endocrinol Metab
Title: Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice.
Publication
First Author: Kim CS
Year: 2020
Journal: Cell Metab
Title: Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle.
Volume: 32
Issue: 4
Pages: 629-642.e8
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Huang L
Year: 2017
Journal: PLoS Biol
Title: Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin.
Volume: 15
Issue: 8
Pages: e2001750
Publication
First Author: Drägert K
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue.
Volume: 473
Issue: 1
Pages: 317-322
Publication
First Author: Sciarretta S
Year: 2015
Journal: Cell Rep
Title: mTORC2 regulates cardiac response to stress by inhibiting MST1.
Volume: 11
Issue: 1
Pages: 125-36
Publication
First Author: Zhou F
Year: 2016
Journal: Nature
Title: Tracing haematopoietic stem cell formation at single-cell resolution.
Volume: 533
Issue: 7604
Pages: 487-92
Publication
First Author: Wang H
Year: 2019
Journal: Virulence
Title: T-cell-specific mTOR deletion in mice ameliorated CD4+ T-cell survival in lethal sepsis induced by severe invasive candidiasis.
Volume: 10
Issue: 1
Pages: 892-901
Publication
First Author: Guo R
Year: 2023
Journal: Int Immunopharmacol
Title: Depletion of mTOR ameliorates CD(4)(+) T cell pyroptosis by promoting autophagy activity in septic mice.
Volume: 124
Issue: Pt B
Pages: 110964
Publication
First Author: Hu T
Year: 2017
Journal: Sci Rep
Title: PDK1 plays a vital role on hematopoietic stem cell function.
Volume: 7
Issue: 1
Pages: 4943
Publication
First Author: Carson RP
Year: 2013
Journal: Hum Mol Genet
Title: Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.
Volume: 22
Issue: 1
Pages: 140-52
Publication
First Author: Shende P
Year: 2016
Journal: Cardiovasc Res
Title: Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.
Volume: 109
Issue: 1
Pages: 103-14
Publication
First Author: Grier MD
Year: 2017
Journal: PLoS One
Title: Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination.
Volume: 12
Issue: 11
Pages: e0188417
Publication
First Author: Najafov A
Year: 2012
Journal: Biochem J
Title: Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors.
Volume: 448
Issue: 2
Pages: 285-95
Publication
First Author: Yang Q
Year: 2006
Journal: Genes Dev
Title: Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.
Volume: 20
Issue: 20
Pages: 2820-32
Publication
First Author: Festuccia WT
Year: 2014
Journal: PLoS One
Title: Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide.
Volume: 9
Issue: 4
Pages: e95432
Publication
First Author: Shrestha S
Year: 2015
Journal: Nat Immunol
Title: Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.
Volume: 16
Issue: 2
Pages: 178-87
Publication  
First Author: Hallowell RW
Year: 2017
Journal: Nat Commun
Title: mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis.
Volume: 8
Pages: 14208
Publication  
First Author: Tang Y
Year: 2016
Journal: Nat Commun
Title: Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
Volume: 7
Pages: 11365
Publication
First Author: Heikamp EB
Year: 2014
Journal: Nat Immunol
Title: The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex.
Volume: 15
Issue: 5
Pages: 457-64
Publication
First Author: Sklarz T
Year: 2017
Journal: Eur J Immunol
Title: mTORC2 regulates multiple aspects of NKT-cell development and function.
Volume: 47
Issue: 3
Pages: 516-526
Publication
First Author: Lee K
Year: 2013
Journal: Blood
Title: Requirement for Rictor in homeostasis and function of mature B lymphoid cells.
Volume: 122
Issue: 14
Pages: 2369-79
Publication
First Author: Hsiao WY
Year: 2020
Journal: Cell Rep
Title: The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development.
Volume: 33
Issue: 1
Pages: 108223
Publication  
First Author: Wu T
Year: 2016
Journal: Sci Rep
Title: mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors.
Volume: 6
Pages: 20250
Publication
First Author: Zhao X
Year: 2014
Journal: Mol Cell Biol
Title: Phosphoinositide-dependent kinase 1 and mTORC2 synergistically maintain postnatal heart growth and heart function in mice.
Volume: 34
Issue: 11
Pages: 1966-75
Publication
First Author: Chen Z
Year: 2015
Journal: J Biol Chem
Title: Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure.
Volume: 290
Issue: 10
Pages: 6387-96
Publication
First Author: Carr TD
Year: 2015
Journal: Carcinogenesis
Title: Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
Volume: 36
Issue: 4
Pages: 487-97
Allele
Name: regulatory associated protein of MTOR, complex 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Publication
First Author: Zhao Y
Year: 2021
Journal: Gastroenterology
Title: mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote KrasG12D-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis.
Volume: 160
Issue: 5
Pages: 1755-1770.e17
Allele  
Name: RPTOR independent companion of MTOR, complex 2; wild type
Allele Type: Not Specified
Publication
First Author: Hagiwara A
Year: 2012
Journal: Cell Metab
Title: Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
Volume: 15
Issue: 5
Pages: 725-38
Publication
First Author: Gerlach BD
Year: 2021
Journal: Cell Metab
Title: Efferocytosis induces macrophage proliferation to help resolve tissue injury.
Volume: 33
Issue: 12
Pages: 2445-2463.e8
Publication
First Author: Lamming DW
Year: 2014
Journal: Aging Cell
Title: Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.
Volume: 13
Issue: 5
Pages: 911-7
Publication
First Author: Newton RH
Year: 2018
Journal: Nat Immunol
Title: Maintenance of CD4 T cell fitness through regulation of Foxo1.
Volume: 19
Issue: 8
Pages: 838-848
Publication
First Author: Werlen G
Year: 2022
Journal: Nat Commun
Title: Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis.
Volume: 13
Issue: 1
Pages: 7404
Publication
First Author: Canaud G
Year: 2013
Journal: Nat Med
Title: AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.
Volume: 19
Issue: 10
Pages: 1288-96
Publication
First Author: Menk AV
Year: 2018
Journal: Cell Rep
Title: Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.
Volume: 22
Issue: 6
Pages: 1509-1521
Publication    
First Author: Yang J
Year: 2016
Journal: Elife
Title: Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.
Volume: 5