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Search results 401 to 500 out of 963 for Parkinson

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Categories

Category: Publication
Type Details Score
Publication  
First Author: Tweedy C
Year: 2021
Journal: Neurobiol Dis
Title: Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein.
Volume: 149
Pages: 105226
Publication  
First Author: Paiva I
Year: 2018
Journal: Neurobiol Dis
Title: Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function.
Volume: 119
Pages: 121-135
Publication
First Author: Cao M
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Absence of Sac2/INPP5F enhances the phenotype of a Parkinson's disease mutation of synaptojanin 1.
Volume: 117
Issue: 22
Pages: 12428-12434
Publication
First Author: Ng XY
Year: 2023
Journal: NPJ Parkinsons Dis
Title: Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology.
Volume: 9
Issue: 1
Pages: 26
Publication
First Author: Takemoto Y
Year: 1999
Journal: Int Immunol
Title: Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3.
Volume: 11
Issue: 12
Pages: 1957-64
Publication
First Author: Higgins JJ
Year: 2006
Journal: Mov Disord
Title: HS1-BP3 gene variant is common in familial essential tremor.
Volume: 21
Issue: 3
Pages: 306-9
Publication
First Author: Smith WW
Year: 2006
Journal: Nat Neurosci
Title: Kinase activity of mutant LRRK2 mediates neuronal toxicity.
Volume: 9
Issue: 10
Pages: 1231-3
Publication  
First Author: Karp NA
Year: 2017
Journal: Nat Commun
Title: Prevalence of sexual dimorphism in mammalian phenotypic traits.
Volume: 8
Pages: 15475
Publication
First Author: Meehan TF
Year: 2017
Journal: Cancer Res
Title: PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.
Volume: 77
Issue: 21
Pages: e62-e66
Publication
First Author: Bowl MR
Year: 2017
Journal: Nat Commun
Title: A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
Volume: 8
Issue: 1
Pages: 886
Publication
First Author: Cacheiro P
Year: 2020
Journal: Nat Commun
Title: Human and mouse essentiality screens as a resource for disease gene discovery.
Volume: 11
Issue: 1
Pages: 655
Publication  
First Author: Sen NE
Year: 2016
Journal: Neurobiol Dis
Title: Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels.
Volume: 96
Pages: 115-126
Publication
First Author: Deeks MJ
Year: 2002
Journal: Trends Plant Sci
Title: Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization.
Volume: 7
Issue: 11
Pages: 492-8
Publication
First Author: Cvrcková F
Year: 2000
Journal: Genome Biol
Title: Are plant formins integral membrane proteins?
Volume: 1
Issue: 1
Pages: RESEARCH001
Publication
First Author: Kim RH
Year: 2006
Journal: Br J Cancer
Title: Tumours and tremors: how PTEN regulation underlies both.
Volume: 94
Issue: 5
Pages: 620-4
Publication
First Author: Dobrikov M
Year: 2011
Journal: Mol Cell Biol
Title: Phosphorylation of eukaryotic translation initiation factor 4G1 (eIF4G1) by protein kinase C{alpha} regulates eIF4G1 binding to Mnk1.
Volume: 31
Issue: 14
Pages: 2947-59
Publication
First Author: Ventoso I
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependent translation.
Volume: 98
Issue: 23
Pages: 12966-71
Publication
First Author: Foeger N
Year: 2003
Journal: J Biol Chem
Title: Human rhinovirus 2 2Apro recognition of eukaryotic initiation factor 4GI. Involvement of an exosite.
Volume: 278
Issue: 35
Pages: 33200-7
Publication
First Author: Adjibade P
Year: 2017
Journal: Sci Rep
Title: DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression.
Volume: 7
Issue: 1
Pages: 13832
Publication
First Author: Zhang XM
Year: 2019
Journal: Hum Mol Genet
Title: The A30P α-synuclein mutation decreases subventricular zone proliferation.
Volume: 28
Issue: 14
Pages: 2283-2294
Publication  
First Author: Taylor TN
Year: 2014
Journal: Neurobiol Dis
Title: Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse.
Volume: 62
Pages: 193-207
Publication
First Author: Bachhuber T
Year: 2015
Journal: Nat Med
Title: Inhibition of amyloid-β plaque formation by α-synuclein.
Volume: 21
Issue: 7
Pages: 802-7
Publication  
First Author: Keomanivong C
Year: 2024
Journal: eNeuro
Title: Mice Expressing A53T/A30P Mutant Alpha-Synuclein in Dopamine Neurons Do Not Display Behavioral Deficits.
Volume: 11
Issue: 2
Publication  
First Author: Pavia-Collado R
Year: 2021
Journal: Int J Mol Sci
Title: Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
Volume: 22
Issue: 6
Publication  
First Author: Paul S
Year: 2022
Journal: eNeuro
Title: Cyclin-Dependent Kinase 5 Regulates cPLA2 Activity and Neuroinflammation in Parkinson's Disease.
Volume: 9
Issue: 6
Publication  
First Author: Jiao F
Year: 2017
Journal: Behav Brain Res
Title: Expression signatures of long non-coding RNA in the substantia nigra of pre-symptomatic mouse model of Parkinson's disease.
Volume: 331
Pages: 123-130
Publication  
First Author: Tiwari S
Year: 2022
Journal: Cells
Title: UBA52 Is Crucial in HSP90 Ubiquitylation and Neurodegenerative Signaling during Early Phase of Parkinson's Disease.
Volume: 11
Issue: 23
Publication
First Author: Yan J
Year: 2017
Journal: PLoS One
Title: Quantitative proteomics in A30P*A53T α-synuclein transgenic mice reveals upregulation of Sel1l.
Volume: 12
Issue: 8
Pages: e0182092
Publication
First Author: Su X
Year: 2015
Journal: PLoS One
Title: PGC-1α Promoter Methylation in Parkinson's Disease.
Volume: 10
Issue: 8
Pages: e0134087
Publication  
First Author: Maraschi A
Year: 2014
Journal: Nat Commun
Title: Parkin regulates kainate receptors by interacting with the GluK2 subunit.
Volume: 5
Pages: 5182
Publication
First Author: Xiang J
Year: 2024
Journal: STAR Protoc
Title: Protocol for screening α-synuclein PET tracer candidates in vitro and ex vivo.
Volume: 5
Issue: 1
Pages: 102788
Publication
First Author: Sato S
Year: 2016
Journal: Am J Pathol
Title: Lysosomal Storage of Subunit c of Mitochondrial ATP Synthase in Brain-Specific Atp13a2-Deficient Mice.
Volume: 186
Issue: 12
Pages: 3074-3082
Publication
First Author: Smidt MP
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons.
Volume: 94
Issue: 24
Pages: 13305-10
Publication
First Author: Fernagut PO
Year: 2004
Journal: Neurobiol Dis
Title: Alpha-synuclein and transgenic mouse models.
Volume: 17
Issue: 2
Pages: 123-30
Publication
First Author: Kéri S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: {alpha}-Synuclein gene duplication impairs reward learning.
Volume: 107
Issue: 36
Pages: 15992-4
Publication
First Author: Meehan TF
Year: 2017
Journal: Nat Genet
Title: Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.
Volume: 49
Issue: 8
Pages: 1231-1238
Publication
First Author: Rozman J
Year: 2018
Journal: Nat Commun
Title: Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
Volume: 9
Issue: 1
Pages: 288
Publication  
First Author: Moore BA
Year: 2018
Journal: Commun Biol
Title: Identification of genes required for eye development by high-throughput screening of mouse knockouts.
Volume: 1
Pages: 236
Publication
First Author: Swan AL
Year: 2020
Journal: PLoS Genet
Title: Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.
Volume: 16
Issue: 12
Pages: e1009190
Publication
First Author: Silady RA
Year: 2008
Journal: Plant J
Title: The GRV2/RME-8 protein of Arabidopsis functions in the late endocytic pathway and is required for vacuolar membrane flow.
Volume: 53
Issue: 1
Pages: 29-41
Publication
First Author: Gustavsson EK
Year: 2015
Journal: Mov Disord
Title: DNAJC13 genetic variants in parkinsonism.
Volume: 30
Issue: 2
Pages: 273-8
Publication  
First Author: Follett J
Year: 2019
Journal: Neurosci Lett
Title: DNAJC13 p.Asn855Ser, implicated in familial parkinsonism, alters membrane dynamics of sorting nexin 1.
Volume: 706
Pages: 114-122
Publication
First Author: Tamura K
Year: 2007
Journal: Plant Cell
Title: Arabidopsis KAM2/GRV2 is required for proper endosome formation and functions in vacuolar sorting and determination of the embryo growth axis.
Volume: 19
Issue: 1
Pages: 320-32
Publication
First Author: Rodriguez-Furlan C
Year: 2019
Journal: Plant Cell
Title: Remove, Recycle, Degrade: Regulating Plasma Membrane Protein Accumulation.
Volume: 31
Issue: 12
Pages: 2833-2854
Publication
First Author: Silady RA
Year: 2004
Journal: Plant Physiol
Title: The gravitropism defective 2 mutants of Arabidopsis are deficient in a protein implicated in endocytosis in Caenorhabditis elegans.
Volume: 136
Issue: 2
Pages: 3095-103; discussion 3002
Publication
First Author: Ko MS
Year: 2021
Journal: Autophagy
Title: Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice.
Volume: 17
Issue: 5
Pages: 1205-1221
Publication
First Author: Xhabija B
Year: 2015
Journal: J Biol Chem
Title: Receptor-mediated Endocytosis 8 Utilizes an N-terminal Phosphoinositide-binding Motif to Regulate Endosomal Clathrin Dynamics.
Volume: 290
Issue: 35
Pages: 21676-89
Publication
First Author: Diggle CP
Year: 2016
Journal: Am J Hum Genet
Title: Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy.
Volume: 98
Issue: 4
Pages: 735-43
Publication
First Author: Gilbert SL
Year: 2006
Journal: Nat Genet
Title: Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice.
Volume: 38
Issue: 2
Pages: 245-50
Publication
First Author: Inglis KJ
Year: 2009
Journal: J Biol Chem
Title: Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system.
Volume: 284
Issue: 5
Pages: 2598-602
Publication
First Author: Zhou B
Year: 2001
Journal: Nat Genet
Title: A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome.
Volume: 28
Issue: 4
Pages: 345-9
Publication
First Author: Ihara M
Year: 2007
Journal: Neuron
Title: Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.
Volume: 53
Issue: 4
Pages: 519-33
Publication
First Author: Lassot I
Year: 2018
Journal: Cell Rep
Title: The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21.
Volume: 25
Issue: 9
Pages: 2484-2496.e9
Publication
First Author: Zhao L
Year: 2005
Journal: Nat Genet
Title: Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP.
Volume: 37
Issue: 9
Pages: 974-9
Publication
First Author: Gyllborg D
Year: 2018
Journal: Stem Cell Reports
Title: The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation.
Volume: 11
Issue: 3
Pages: 651-664
Publication
First Author: Sharma R
Year: 2007
Journal: J Neurochem
Title: Minimal role for caspase 12 in the unfolded protein response in oligodendrocytes in vivo.
Volume: 101
Issue: 4
Pages: 889-97
Publication
First Author: Zlatic SA
Year: 2018
Journal: Cell Syst
Title: Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees.
Volume: 6
Issue: 3
Pages: 368-380.e6
Publication
First Author: Liss B
Year: 2005
Journal: Nat Neurosci
Title: K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons.
Volume: 8
Issue: 12
Pages: 1742-51
Publication
First Author: Ding Y
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Enhanced striatal cholinergic neuronal activity mediates L-DOPA-induced dyskinesia in parkinsonian mice.
Volume: 108
Issue: 2
Pages: 840-5
Publication
First Author: Rekaik H
Year: 2015
Journal: Cell Rep
Title: Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress.
Volume: 13
Issue: 2
Pages: 242-50
Publication
First Author: Kittappa R
Year: 2007
Journal: PLoS Biol
Title: The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age.
Volume: 5
Issue: 12
Pages: e325
Publication  
First Author: Hedlund E
Year: 2016
Journal: Sci Rep
Title: Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors.
Volume: 6
Pages: 26448
Publication
First Author: Sterky FH
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo.
Volume: 108
Issue: 31
Pages: 12937-42
Publication
First Author: Andrews ZB
Year: 2006
Journal: Neurobiol Dis
Title: Transforming growth factor beta2 haploinsufficient mice develop age-related nigrostriatal dopamine deficits.
Volume: 21
Issue: 3
Pages: 568-75
Publication  
First Author: González-Barbosa E
Year: 2017
Journal: J Biochem Mol Toxicol
Title: TCDD induces UbcH7 expression and synphilin-1 protein degradation in the mouse ventral midbrain.
Volume: 31
Issue: 10
Publication
First Author: Orb S
Year: 2004
Journal: Physiol Genomics
Title: Knockin mice with Leu9'Ser alpha4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally.
Volume: 18
Issue: 3
Pages: 299-307
Publication
First Author: Mistry PK
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage.
Volume: 107
Issue: 45
Pages: 19473-8
Publication
First Author: Jang SW
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone.
Volume: 107
Issue: 6
Pages: 2687-92
Publication
First Author: Tesseur I
Year: 2017
Journal: J Neurosci
Title: Deficiency in Neuronal TGF-β Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-β Signaling Protects against MPTP Neurotoxicity in Mice.
Volume: 37
Issue: 17
Pages: 4584-4592
Publication
First Author: Migdalska-Richards A
Year: 2020
Journal: PLoS One
Title: L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils.
Volume: 15
Issue: 8
Pages: e0238075
Publication
First Author: Kim J
Year: 2017
Journal: Neuron
Title: Inhibitory Basal Ganglia Inputs Induce Excitatory Motor Signals in the Thalamus.
Volume: 95
Issue: 5
Pages: 1181-1196.e8
Publication    
First Author: Lasagna-Reeves CA
Year: 2015
Journal: Elife
Title: A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
Volume: 4
Publication
First Author: Rothaug M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance.
Volume: 111
Issue: 43
Pages: 15573-8
Publication
First Author: Shioda N
Year: 2014
Journal: J Biol Chem
Title: FABP3 protein promotes α-synuclein oligomerization associated with 1-methyl-1,2,3,6-tetrahydropiridine-induced neurotoxicity.
Volume: 289
Issue: 27
Pages: 18957-65
Publication
First Author: Sardi SP
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy.
Volume: 108
Issue: 29
Pages: 12101-6
Publication
First Author: Chen FW
Year: 2022
Journal: iScience
Title: Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction.
Volume: 25
Issue: 9
Pages: 104941
Publication
First Author: Winner B
Year: 2008
Journal: Neurobiol Aging
Title: Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis.
Volume: 29
Issue: 6
Pages: 913-25
Publication
First Author: Subramaniam M
Year: 2014
Journal: J Neurosci
Title: Mutant α-synuclein enhances firing frequencies in dopamine substantia nigra neurons by oxidative impairment of A-type potassium channels.
Volume: 34
Issue: 41
Pages: 13586-99
Publication
First Author: Tsvetkov AS
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model.
Volume: 107
Issue: 39
Pages: 16982-7
Publication
First Author: Lindsten K
Year: 2003
Journal: Nat Biotechnol
Title: A transgenic mouse model of the ubiquitin/proteasome system.
Volume: 21
Issue: 8
Pages: 897-902
Publication
First Author: Wei ZB
Year: 2016
Journal: Autophagy
Title: SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation.
Volume: 12
Issue: 7
Pages: 1168-79
Publication
First Author: Decressac M
Year: 2012
Journal: Sci Transl Med
Title: α-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons.
Volume: 4
Issue: 163
Pages: 163ra156
Publication
First Author: Leon J
Year: 2017
Journal: Cell Rep
Title: Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice.
Volume: 20
Issue: 6
Pages: 1360-1371
Publication
First Author: Ding J
Year: 2006
Journal: Nat Neurosci
Title: RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion.
Volume: 9
Issue: 6
Pages: 832-42
Publication
First Author: Kett LR
Year: 2016
Journal: Mov Disord
Title: Endolysosomal dysfunction in Parkinson's disease: Recent developments and future challenges.
Volume: 31
Issue: 10
Pages: 1433-1443
Publication  
First Author: Sun H
Year: 2016
Journal: Neuroscience
Title: Aquaporin-4 mediates communication between astrocyte and microglia: Implications of neuroinflammation in experimental Parkinson's disease.
Volume: 317
Pages: 65-75
Publication
First Author: Doxakis E
Year: 2010
Journal: J Biol Chem
Title: Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153.
Volume: 285
Issue: 17
Pages: 12726-34
Publication
First Author: Mendez JA
Year: 2011
Journal: J Biol Chem
Title: Somatodendritic dopamine release requires synaptotagmin 4 and 7 and the participation of voltage-gated calcium channels.
Volume: 286
Issue: 27
Pages: 23928-37
Publication
First Author: Grandy DK
Year: 1992
Journal: Genomics
Title: Chromosomal localization of three human D5 dopamine receptor genes.
Volume: 13
Issue: 4
Pages: 968-73
Publication
First Author: Davies RW
Year: 1994
Journal: Genomics
Title: Enhanced access to rare brain cDNAs by prescreening libraries: 207 new mouse brain ESTs.
Volume: 24
Issue: 3
Pages: 456-63
Publication
First Author: Stewart GJ
Year: 1997
Journal: Genomics
Title: Sequence analysis of 497 mouse brain ESTs expressed in the substantia nigra.
Volume: 39
Issue: 2
Pages: 147-53
Publication
First Author: Ackerman SL
Year: 1998
Journal: Genomics
Title: Cloning and mapping of the UNC5C gene to human chromosome 4q21-q23.
Volume: 52
Issue: 2
Pages: 205-8
Publication
First Author: Schiavon E
Year: 2006
Journal: J Biol Chem
Title: Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons.
Volume: 281
Issue: 29
Pages: 20326-37
Publication
First Author: Martinez-Vicente M
Year: 2008
Journal: J Clin Invest
Title: Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.
Volume: 118
Issue: 2
Pages: 777-88
Publication
First Author: Friling S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells.
Volume: 106
Issue: 18
Pages: 7613-8
Publication
First Author: Koike M
Year: 2010
Journal: J Biol Chem
Title: Valosin-containing protein (VCP) in novel feedback machinery between abnormal protein accumulation and transcriptional suppression.
Volume: 285
Issue: 28
Pages: 21736-49
Publication
First Author: Mizushima N
Year: 2011
Journal: Cell
Title: Autophagy: renovation of cells and tissues.
Volume: 147
Issue: 4
Pages: 728-41
Publication
First Author: Cherra SJ 3rd
Year: 2013
Journal: Am J Pathol
Title: Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons.
Volume: 182
Issue: 2
Pages: 474-84
Publication
First Author: Young A
Year: 2014
Journal: Cancer Discov
Title: Targeting cancer-derived adenosine: new therapeutic approaches.
Volume: 4
Issue: 8
Pages: 879-88
Publication
First Author: Nuber S
Year: 2010
Journal: Neurogenetics
Title: Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice.
Volume: 11
Issue: 1
Pages: 107-20