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Search results 101 to 200 out of 701 for Akt2

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Type Details Score
Publication
First Author: Hu N
Year: 2014
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Hydrogen sulfide alleviates cardiac contractile dysfunction in an Akt2-knockout murine model of insulin resistance: role of mitochondrial injury and apoptosis.
Volume: 306
Issue: 10
Pages: R761-71
Publication
First Author: Southgate RJ
Year: 2005
Journal: FASEB J
Title: PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.
Volume: 19
Issue: 14
Pages: 2072-4
Publication
First Author: Ren J
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy.
Volume: 1865
Issue: 1
Pages: 206-217
Publication
First Author: Gonzalez E
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Insulin-modulated Akt subcellular localization determines Akt isoform-specific signaling.
Volume: 106
Issue: 17
Pages: 7004-9
Publication
First Author: Gonzalez I
Year: 2004
Journal: Mol Cell Biol
Title: Akt2, a novel functional link between p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways in myogenesis.
Volume: 24
Issue: 9
Pages: 3607-22
Publication
First Author: Wu JC
Year: 2019
Journal: World J Gastroenterol
Title: MicroRNA-194 inactivates hepatic stellate cells and alleviates liver fibrosis by inhibiting AKT2.
Volume: 25
Issue: 31
Pages: 4468-4480
Publication
First Author: Wu L
Year: 2023
Journal: Biochem Genet
Title: CircRNA Circ_0000118 Regulates Malignancy of Cervical Cancer Cells by Regulating miR-211-5p/miR-377-3p/AKT2 Axis.
Volume: 61
Issue: 4
Pages: 1625-1644
Publication
First Author: Ackah E
Year: 2005
Journal: J Clin Invest
Title: Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis.
Volume: 115
Issue: 8
Pages: 2119-27
Publication
First Author: Bottermann K
Year: 2013
Journal: PLoS One
Title: Systematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2.
Volume: 8
Issue: 6
Pages: e66045
Publication
First Author: Xie X
Year: 2011
Journal: Cell Metab
Title: C2 domain-containing phosphoprotein CDP138 regulates GLUT4 insertion into the plasma membrane.
Volume: 14
Issue: 3
Pages: 378-89
Publication
First Author: Shearin AL
Year: 2016
Journal: Mol Metab
Title: Lack of AKT in adipocytes causes severe lipodystrophy.
Volume: 5
Issue: 7
Pages: 472-479
Publication
First Author: Balsevich G
Year: 2017
Journal: Nat Commun
Title: Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.
Volume: 8
Issue: 1
Pages: 1725
Publication
First Author: Ieronymaki E
Year: 2019
Journal: J Immunol
Title: Insulin Resistance in Macrophages Alters Their Metabolism and Promotes an M2-Like Phenotype.
Volume: 202
Issue: 6
Pages: 1786-1797
Publication
First Author: Wan M
Year: 2013
Journal: Cell Metab
Title: A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition.
Volume: 18
Issue: 1
Pages: 99-105
Publication
First Author: Wang Q
Year: 2016
Journal: Cancer Cell
Title: Spontaneous Hepatocellular Carcinoma after the Combined Deletion of Akt Isoforms.
Volume: 29
Issue: 4
Pages: 523-535
Publication
First Author: Kramer HF
Year: 2006
Journal: Diabetes
Title: Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle.
Volume: 55
Issue: 7
Pages: 2067-76
Publication
First Author: Rensing KL
Year: 2014
Journal: Cardiovasc Res
Title: Akt2/LDLr double knockout mice display impaired glucose tolerance and develop more complex atherosclerotic plaques than LDLr knockout mice.
Volume: 101
Issue: 2
Pages: 277-87
Publication
First Author: Hollander MC
Year: 2011
Journal: Carcinogenesis
Title: A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.
Volume: 32
Issue: 8
Pages: 1279-84
Publication
First Author: Xie Y
Year: 2015
Journal: Sci Signal
Title: Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition.
Volume: 8
Issue: 376
Pages: ra44
Publication
First Author: Ouyang S
Year: 2019
Journal: J Immunol
Title: Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells.
Volume: 202
Issue: 5
Pages: 1441-1452
Publication
First Author: Wofford JA
Year: 2008
Journal: Blood
Title: IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival.
Volume: 111
Issue: 4
Pages: 2101-11
Publication
First Author: Chang X
Year: 2012
Journal: Eur J Immunol
Title: Sin1 regulates Treg-cell development but is not required for T-cell growth and proliferation.
Volume: 42
Issue: 6
Pages: 1639-47
Publication
First Author: Toda G
Year: 2020
Journal: Mol Cell
Title: Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation.
Volume: 79
Issue: 1
Pages: 43-53.e4
Publication
First Author: He L
Year: 2020
Journal: Biochem J
Title: Regulation of basal expression of hepatic PEPCK and G6Pase by AKT2.
Volume: 477
Issue: 5
Pages: 1021-1031
Publication
First Author: Galicia VA
Year: 2010
Journal: Gastroenterology
Title: Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2.
Volume: 139
Issue: 6
Pages: 2170-82
Publication
First Author: Yin H
Year: 2008
Journal: Blood
Title: The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation.
Volume: 111
Issue: 2
Pages: 658-65
Publication
First Author: Vichaiwong K
Year: 2010
Journal: Biochem J
Title: Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle.
Volume: 431
Issue: 2
Pages: 311-20
Publication
First Author: Chen J
Year: 2010
Journal: Blood
Title: Akt isoforms differentially regulate neutrophil functions.
Volume: 115
Issue: 21
Pages: 4237-46
Publication
First Author: Mukherjee A
Year: 2014
Journal: PLoS One
Title: Distinct actions of akt1 on skeletal architecture and function.
Volume: 9
Issue: 3
Pages: e93040
Publication  
First Author: Kim SH
Year: 2022
Journal: Int J Mol Sci
Title: Protein Kinase B2 (PKB2/AKT2) Is Essential for Host Protection in CVB3-Induced Acute Viral Myocarditis.
Volume: 23
Issue: 3
Publication
First Author: Easton RM
Year: 2005
Journal: Mol Cell Biol
Title: Role for Akt3/protein kinase Bgamma in attainment of normal brain size.
Volume: 25
Issue: 5
Pages: 1869-78
Publication
First Author: Li D
Year: 2008
Journal: Blood
Title: GSK3beta is a negative regulator of platelet function and thrombosis.
Volume: 111
Issue: 7
Pages: 3522-30
Publication
First Author: Domènech-Estévez E
Year: 2016
Journal: J Neurosci
Title: Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS.
Volume: 36
Issue: 16
Pages: 4506-21
Publication
First Author: Tang H
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.
Volume: 308
Issue: 2
Pages: L208-20
Publication
First Author: Borst O
Year: 2012
Journal: Circ Res
Title: The inflammatory chemokine CXC motif ligand 16 triggers platelet activation and adhesion via CXC motif receptor 6-dependent phosphatidylinositide 3-kinase/Akt signaling.
Volume: 111
Issue: 10
Pages: 1297-307
Publication
First Author: Kofuji S
Year: 2015
Journal: Cancer Discov
Title: INPP4B Is a PtdIns(3,4,5)P3 Phosphatase That Can Act as a Tumor Suppressor.
Volume: 5
Issue: 7
Pages: 730-9
Publication
First Author: Al-Regaiey KA
Year: 2007
Journal: J Gerontol A Biol Sci Med Sci
Title: Effects of caloric restriction and growth hormone resistance on insulin-related intermediates in the skeletal muscle.
Volume: 62
Issue: 1
Pages: 18-26
Publication
First Author: Tsen F
Year: 2013
Journal: Mol Cell Biol
Title: Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo.
Volume: 33
Issue: 24
Pages: 4947-59
Publication  
First Author: Sun W
Year: 2014
Journal: Free Radic Biol Med
Title: Renal improvement by zinc in diabetic mice is associated with glucose metabolism signaling mediated by metallothionein and Akt, but not Akt2.
Volume: 68
Pages: 22-34
Publication
First Author: Kinross KM
Year: 2015
Journal: FASEB J
Title: Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly.
Volume: 29
Issue: 4
Pages: 1426-34
Publication
First Author: Yao LJ
Year: 2011
Journal: Mol Endocrinol
Title: Novel role for SGK3 in glucose homeostasis revealed in SGK3/Akt2 double-null mice.
Volume: 25
Issue: 12
Pages: 2106-18
Publication
First Author: Wang C
Year: 2016
Journal: Liver Int
Title: Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade.
Volume: 36
Issue: 8
Pages: 1176-86
Publication
First Author: Iliopoulos D
Year: 2009
Journal: Sci Signal
Title: MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.
Volume: 2
Issue: 92
Pages: ra62
Publication
First Author: Levenga J
Year: 2021
Journal: Cereb Cortex Commun
Title: Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT's Role in Complex Brain Disorders and Neurological Disease.
Volume: 2
Issue: 2
Pages: tgab036
Publication      
First Author: Fiorenza MT
Year: 2019
Journal: J Cell Physiol
Title: Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos.
Publication
First Author: Takenaka N
Year: 2014
Journal: Cell Signal
Title: Role of the guanine nucleotide exchange factor in Akt2-mediated plasma membrane translocation of GLUT4 in insulin-stimulated skeletal muscle.
Volume: 26
Issue: 11
Pages: 2460-9
Publication
First Author: Takenaka N
Year: 2014
Journal: FEBS J
Title: A critical role of the small GTPase Rac1 in Akt2-mediated GLUT4 translocation in mouse skeletal muscle.
Volume: 281
Issue: 5
Pages: 1493-504
Publication
First Author: Yang W
Year: 2014
Journal: Cell Physiol Biochem
Title: Akt2- and ETS1-dependent IP3 receptor 2 expression in dendritic cell migration.
Volume: 33
Issue: 1
Pages: 222-36
Publication
First Author: Kunuthur SP
Year: 2012
Journal: J Cell Mol Med
Title: The Akt1 isoform is an essential mediator of ischaemic preconditioning.
Volume: 16
Issue: 8
Pages: 1739-49
Publication
First Author: Babaev VR
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.
Volume: 39
Issue: 2
Pages: 156-169
Publication
First Author: Titchenell PM
Year: 2016
Journal: Cell Metab
Title: Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.
Volume: 23
Issue: 6
Pages: 1154-1166
Publication
First Author: Espeillac C
Year: 2011
Journal: J Clin Invest
Title: S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy.
Volume: 121
Issue: 7
Pages: 2821-32
Publication
First Author: Boxer RB
Year: 2006
Journal: Cell Metab
Title: Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.
Volume: 4
Issue: 6
Pages: 475-90
Publication
First Author: Mao C
Year: 2007
Journal: J Immunol
Title: Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition.
Volume: 178
Issue: 9
Pages: 5443-53
Publication
First Author: Chen WS
Year: 2009
Journal: Mol Cell Biol
Title: Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice.
Volume: 29
Issue: 11
Pages: 3151-62
Publication
First Author: Patitucci C
Year: 2017
Journal: J Clin Invest
Title: Hepatocyte nuclear factor 1α suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription.
Volume: 127
Issue: 5
Pages: 1873-1888
Publication  
First Author: Panasyuk G
Year: 2012
Journal: Nat Commun
Title: PPARγ contributes to PKM2 and HK2 expression in fatty liver.
Volume: 3
Pages: 672
Publication
First Author: Peng XD
Year: 2003
Journal: Genes Dev
Title: Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.
Volume: 17
Issue: 11
Pages: 1352-65
Publication
First Author: Minhajuddin M
Year: 2009
Journal: J Biol Chem
Title: Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells.
Volume: 284
Issue: 7
Pages: 4052-61
Publication  
First Author: Sanchez-Gurmaches J
Year: 2019
Journal: Mol Metab
Title: Brown fat organogenesis and maintenance requires AKT1 and AKT2.
Volume: 23
Pages: 60-74
Publication  
First Author: Wang Q
Year: 2016
Journal: Pharmacol Res
Title: mTOR-Independent autophagy inducer trehalose rescues against insulin resistance-induced myocardial contractile anomalies: Role of p38 MAPK and Foxo1.
Volume: 111
Pages: 357-373
Publication
First Author: Tan Y
Year: 2010
Journal: J Biol Chem
Title: Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts.
Volume: 285
Issue: 9
Pages: 6377-89
Publication
First Author: Qiao G
Year: 2013
Journal: J Immunol
Title: T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells.
Volume: 191
Issue: 2
Pages: 632-9
Publication  
First Author: Simoes DCM
Year: 2022
Journal: J Cell Biol
Title: An integrin axis induces IFN-β production in plasmacytoid dendritic cells.
Volume: 221
Issue: 9
Publication
First Author: Rajala A
Year: 2013
Journal: J Biol Chem
Title: Insulin receptor signaling in cones.
Volume: 288
Issue: 27
Pages: 19503-15
Publication
First Author: Perry RJ
Year: 2015
Journal: Cell
Title: Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.
Volume: 160
Issue: 4
Pages: 745-58
Publication
First Author: Jeffery E
Year: 2015
Journal: Nat Cell Biol
Title: Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity.
Volume: 17
Issue: 4
Pages: 376-85
Publication
First Author: Chen CC
Year: 2012
Journal: Genes Dev
Title: Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways.
Volume: 26
Issue: 19
Pages: 2154-68
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Kellenberger LD
Year: 2018
Journal: Gynecol Oncol
Title: Hyperglycemia promotes insulin-independent ovarian tumor growth.
Volume: 149
Issue: 2
Pages: 361-370
Publication  
First Author: Kokona D
Year: 2021
Journal: Neuropharmacology
Title: The endocannabinoid 2-arachidonoylglycerol and dual ABHD6/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity.
Volume: 185
Pages: 108450
Publication
First Author: Garofalo RS
Year: 2003
Journal: J Clin Invest
Title: Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta.
Volume: 112
Issue: 2
Pages: 197-208
Publication
First Author: Balzano D
Year: 2015
Journal: J Biol Chem
Title: Alternative Activation Mechanisms of Protein Kinase B Trigger Distinct Downstream Signaling Responses.
Volume: 290
Issue: 41
Pages: 24975-85
Publication
First Author: Staal SP
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.
Volume: 84
Issue: 14
Pages: 5034-7
Publication
First Author: Ohba N
Year: 2004
Journal: Neurosci Lett
Title: Transgenic mouse overexpressing the Akt reduced the volume of infarct area after middle cerebral artery occlusion.
Volume: 359
Issue: 3
Pages: 159-62
GXD Expression        
Probe: MGI:3842952
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3843031
Age: postnatal newborn
Specimen Label: Brain
Specimen Num: 1
GXD Expression      
Probe: MGI:3842952
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:3843031
Age: postnatal newborn
Specimen Label: Brown fat
Detected: true
Specimen Num: 2
GXD Expression        
Probe: MGI:3842952
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3843031
Age: postnatal newborn
Specimen Label: Heart
Specimen Num: 3
GXD Expression        
Probe: MGI:3842952
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:3843031
Age: postnatal newborn
Specimen Label: Kidney
Specimen Num: 4
GXD Expression        
Probe: MGI:3842952
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:3843031
Age: postnatal newborn
Specimen Label: Liver
Specimen Num: 5
GXD Expression        
Probe: MGI:3842952
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:3843031
Age: postnatal newborn
Specimen Label: Lung
Specimen Num: 6
GXD Expression        
Probe: MGI:3842952
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3598827
Stage: TS27
Assay Id: MGI:3843031
Age: postnatal newborn
Specimen Label: Skeletal muscle
Specimen Num: 7