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Search results 101 to 198 out of 198 for Ssrp1

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0.026s
Type Details Score
GXD Expression  
Probe: MGI:3506249
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280927
Stage: TS27
Assay Id: MGI:3507775
Age: postnatal newborn
Image: 2
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506249
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267921
Stage: TS21
Assay Id: MGI:3507775
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506249
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3507775
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506249
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539272
Age: embryonic day 15.5
Image: GUDMAP:5564
Specimen Label: GUDMAP:5564
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3506249
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3507775
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506249
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3507775
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506249
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539272
Age: embryonic day 15.5
Image: GUDMAP:5564
Specimen Label: GUDMAP:5564
Detected: true
Specimen Num: 1
Publication
First Author: Souslova V
Year: 1997
Journal: Gene
Title: Structure and chromosomal mapping of the mouse P2X3 gene.
Volume: 195
Issue: 1
Pages: 101-11
Publication
First Author: Avvakumov N
Year: 2011
Journal: Mol Cell
Title: Histone chaperones: modulators of chromatin marks.
Volume: 41
Issue: 5
Pages: 502-14
Publication
First Author: Vethantham V
Year: 2012
Journal: Mol Cell Biol
Title: Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation.
Volume: 32
Issue: 6
Pages: 1044-55
Publication
First Author: Pilon AL
Year: 1993
Journal: Mamm Genome
Title: Localization of the murine Hmg1 gene, encoding an HMG-box protein, to mouse chromosome 2.
Volume: 4
Issue: 10
Pages: 612-4
Publication
First Author: Silver A
Year: 1999
Journal: Genes Chromosomes Cancer
Title: Molecular mapping of chromosome 2 deletions in murine radiation-induced AML localizes a putative tumor suppressor gene to a 1.0 cM region homologous to human chromosome segment 11p11-12.
Volume: 24
Issue: 2
Pages: 95-104
Publication
First Author: Huppi K
Year: 1993
Journal: Immunogenetics
Title: Genes associated with immunoglobulin V(D)J recombination are linked on mouse chromosome 2 and human chromosome 11.
Volume: 37
Issue: 4
Pages: 288-91
Publication  
First Author: Vied CM
Year: 2014
Journal: Front Neurosci
Title: A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development.
Volume: 8
Pages: 257
Publication
First Author: Nagai K
Year: 2001
Journal: Gene
Title: Molecular evolution of Sry and Sox gene.
Volume: 270
Issue: 1-2
Pages: 161-9
Publication  
First Author: Elsen GE
Year: 2018
Journal: Front Neurosci
Title: The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.
Volume: 12
Pages: 571
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
Protein
Organism: Mus musculus/domesticus
Length: 623  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 633  
Fragment?: true
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Protein
Organism: Mus musculus/domesticus
Length: 713  
Fragment?: false
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
UniProt Feature
Begin: 2
Description: FACT complex subunit SSRP1
Type: chain
End: 708
Protein Domain
Type: Homologous_superfamily
Description: This is the dimerization domain found in structure-specific recognition protein SSRP1 (POB3 in yeast) and related proteins, which are components of the FACT complex - a general chromatin factor that acts to reorganise nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair [, , , ]. During transcription elongation the FACT complex acts as a histone chaperone that both destabilises and restores nucleosomal structure [, ].This domain has a Pleckstrin homology fold, made of 6 β-strands.
Publication
First Author: Mason PB
Year: 2003
Journal: Mol Cell Biol
Title: The FACT complex travels with elongating RNA polymerase II and is important for the fidelity of transcriptional initiation in vivo.
Volume: 23
Issue: 22
Pages: 8323-33
Publication
First Author: Schlesinger MB
Year: 2000
Journal: Genetics
Title: POB3 is required for both transcription and replication in the yeast Saccharomyces cerevisiae.
Volume: 155
Issue: 4
Pages: 1593-606
Publication
First Author: Orphanides G
Year: 1998
Journal: Cell
Title: FACT, a factor that facilitates transcript elongation through nucleosomes.
Volume: 92
Issue: 1
Pages: 105-16
Publication  
First Author: Zhang W
Year: 2015
Journal: Sci Rep
Title: Crystal Structure of Human SSRP1 Middle Domain Reveals a Role in DNA Binding.
Volume: 5
Pages: 18688
Publication
First Author: Tsunaka Y
Year: 2016
Journal: Genes Dev
Title: Integrated molecular mechanism directing nucleosome reorganization by human FACT.
Volume: 30
Issue: 6
Pages: 673-86
Interaction Experiment
Description: CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin.
Publication
First Author: Kelley DE
Year: 1999
Journal: Chromosoma
Title: CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin.
Volume: 108
Issue: 1
Pages: 10-25
Publication
First Author: Lolis AA
Year: 2013
Journal: J Biol Chem
Title: Myogenin recruits the histone chaperone facilitates chromatin transcription (FACT) to promote nucleosome disassembly at muscle-specific genes.
Volume: 288
Issue: 11
Pages: 7676-87
Publication
First Author: Belotserkovskaya R
Year: 2003
Journal: Science
Title: FACT facilitates transcription-dependent nucleosome alteration.
Volume: 301
Issue: 5636
Pages: 1090-3
Publication
First Author: Liu Y
Year: 2020
Journal: Nature
Title: FACT caught in the act of manipulating the nucleosome.
Volume: 577
Issue: 7790
Pages: 426-431
Publication
First Author: Hondele M
Year: 2013
Journal: Nature
Title: Structural basis of histone H2A-H2B recognition by the essential chaperone FACT.
Volume: 499
Issue: 7456
Pages: 111-4
Publication
First Author: Singer RA
Year: 2004
Journal: Biochem Cell Biol
Title: The FACT chromatin modulator: genetic and structure/function relationships.
Volume: 82
Issue: 4
Pages: 419-27
Protein Domain
Type: Domain
Description: This domain is found at the N terminus of yeast POB3 and its metazoan homologue SSRP1 [, ]. POB3/SSRP1 is a subunit of the heterodimeric FACT complex involved in transcriptional initiation [, , ].
Publication
First Author: Bruhn SL
Year: 1993
Journal: Nucleic Acids Res
Title: Isolation and characterization of cDNA clones encoding the Drosophila homolog of the HMG-box SSRP family that recognizes specific DNA structures.
Volume: 21
Issue: 7
Pages: 1643-6
Publication
First Author: Bruhn SL
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin.
Volume: 89
Issue: 6
Pages: 2307-11
Publication
First Author: Hsu T
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: A Drosophila single-strand DNA/RNA-binding factor contains a high-mobility-group box and is enriched in the nucleolus.
Volume: 90
Issue: 14
Pages: 6488-92
Publication
First Author: Huang S
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing.
Volume: 102
Issue: 38
Pages: 13410-5
Publication
First Author: Kemble DJ
Year: 2013
Journal: J Biol Chem
Title: Structure of the Spt16 middle domain reveals functional features of the histone chaperone FACT.
Volume: 288
Issue: 15
Pages: 10188-94
Protein Domain
Type: Family
Description: FACT (facilitates chromatin transactions) is a general chromatin factor that acts to reorganise nucleosomes. It is a complex that consists of several subunits [, , , ]. This entry represents the FACT complex subunits POB3, which is present in yeast, and the related SSRP1, found in higher eukaryotes. SSRP1 binds specifically to DNA modified with the anti-cancer drug cisplatin. It contains a high mobility group (HMG) box domain () that probably constitutes the structure recognition element for cisplatin-modified DNA, the probable recognition motif being the local duplex unwinding and bending that occurs on formation of intra-strand cross-links [, , ].
Protein Domain
Type: Domain
Description: This is the dimerization domain found in structure-specific recognition protein SSRP1 (POB3 in yeast) and related proteins, which are components of the FACT complex - a general chromatin factor that acts to reorganise nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair [, , , ]. During transcription elongation the FACT complex acts as a histone chaperone that both destabilises and restores nucleosomal structure [, ].This domain has a Pleckstrin homology fold, made of 6 β-strands.
Protein Domain
Type: Domain
Description: This entry represents a domain found in the middle region of several eukaryotic proteins [, ]. It is present in various FACT (facilitates chromatin transactions) complex subunits, such as Spt16 and either Pob3 (yeast) or the related SSRP1 (higher eukaryotes). FACT is a general chromatin factor that acts to reorganise nucleosomes [, ]. In these proteins, the middle domain shows a double pleckstrin homology (PH) configuration and plays a role in DNA binding [, , ]. This entry represents the second PH domain, which is also found in Rtt106p, a histone chaperone involved in heterochromatin-mediated silencing [].
Publication
First Author: Winkler DD
Year: 2011
Journal: J Biol Chem
Title: The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization.
Volume: 286
Issue: 21
Pages: 18369-74
Publication
First Author: Farnung L
Year: 2021
Journal: Nat Struct Mol Biol
Title: Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Volume: 28
Issue: 4
Pages: 382-387
Publication
First Author: Ishov AM
Year: 2004
Journal: J Cell Sci
Title: Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX.
Volume: 117
Issue: Pt 17
Pages: 3807-20
Publication  
First Author: Wang QS
Year: 2024
Journal: Int Immunopharmacol
Title: MiR-204/-211 double knockout exacerbates rheumatoid arthritis progression by promoting splenic inflammation.
Volume: 140
Pages: 112850
Publication
First Author: Shimojima T
Year: 2003
Journal: Genes Dev
Title: Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor.
Volume: 17
Issue: 13
Pages: 1605-16
Publication
First Author: Wittmeyer J
Year: 1999
Journal: Biochemistry
Title: Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase alpha.
Volume: 38
Issue: 28
Pages: 8961-71
Publication
First Author: Biswas D
Year: 2005
Journal: Mol Cell Biol
Title: The yeast FACT complex has a role in transcriptional initiation.
Volume: 25
Issue: 14
Pages: 5812-22
Publication
First Author: Formosa T
Year: 2002
Journal: Genetics
Title: Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure.
Volume: 162
Issue: 4
Pages: 1557-71
Protein
Organism: Mus musculus/domesticus
Length: 1047  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1047  
Fragment?: false
Publication
First Author: Sweet SM
Year: 2009
Journal: Mol Cell Proteomics
Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.
Volume: 8
Issue: 5
Pages: 904-12
Publication
First Author: Trost M
Year: 2009
Journal: Immunity
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
Volume: 30
Issue: 1
Pages: 143-54
Publication
First Author: Park J
Year: 2013
Journal: Mol Cell
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
Volume: 50
Issue: 6
Pages: 919-30
Publication
First Author: Villén J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Large-scale phosphorylation analysis of mouse liver.
Volume: 104
Issue: 5
Pages: 1488-93
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112