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Search results 101 to 200 out of 312 for Vps13a

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Type Details Score
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Protein
Organism: Mus musculus/domesticus
Length: 9  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1186  
Fragment?: true
UniProt Feature
Begin: 1
Description: Intermembrane lipid transfer protein VPS13A
Type: chain
End: 3166
Publication  
First Author: Ryoden Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Requirement of Xk and Vps13a for the P2X7-mediated phospholipid scrambling and cell lysis in mouse T cells.
Volume: 119
Issue: 7
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Protein
Organism: Mus musculus/domesticus
Length: 3166  
Fragment?: false
Publication
First Author: Mizuno E
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Brain-specific transcript variants of 5' and 3' ends of mouse VPS13A and VPS13C.
Volume: 353
Issue: 4
Pages: 902-7
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein
Organism: Mus musculus/domesticus
Length: 3061  
Fragment?: false
Gene
Type: gene
Organism: frog, African clawed
Allele
Name: vacuolar protein sorting 13A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication    
First Author: Yeshaw WM
Year: 2019
Journal: Elife
Title: Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility.
Volume: 8
Publication  
First Author: Muñoz-Braceras S
Year: 2019
Journal: Dis Model Mech
Title: VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation.
Volume: 12
Issue: 2
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
Publication
First Author: Kumar N
Year: 2018
Journal: J Cell Biol
Title: VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.
Volume: 217
Issue: 10
Pages: 3625-3639
Allele
Name: vacuolar protein sorting 13A; targeted mutation 1, Akira Sano
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Vps13a/Vps13a
Background: involves: 129S/SvEv * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
DO Term
Publication
First Author: Suzuki J
Year: 2014
Journal: J Biol Chem
Title: Exposure of phosphatidylserine by Xk-related protein family members during apoptosis.
Volume: 289
Issue: 44
Pages: 30257-67
Protein Domain
Type: Domain
Description: This entry represents a domain reminiscent of a DH domain (DH-Like domain) found adjacent the C-terminal PH-like domain of VPS13 proteins [, , , ]. DHL-PH domains has been identified as the mitochondria-binding region of VPS13A and the lipid droplet-binding region of both proteins. These two domains contain a region of high similarity to ATG2, which also binds lipid droplets [, ].VPS13 proteins have been implicated in processes including vesicle fusion, autophagy, and actin regulation. They bind phospholipids and act as channels that mediate the transfer of lipids between membranes at organelle contact sites [, , ]. It has been proposed that members of this entry have the capacity to bind and likely transfer tens of glycerolipids at once. Yeast VPS13 acts at multiple cellular sites, namely the interface between mitochondria and the vacuole, on endosomes, on the nuclear-vacuole junction and the vacuole, depending on the carbon source and metabolic state. Most evidence showed that mammalian VPS13A, VPS13C and VPS13D localize at contacts between the ER and other organelles, i.e. VPS13A and VPS13D bridge the ER to mitochondria, VPS13C bridges the ER to late endosomes and lysosomes and VPS13B may localize to endosome-endosome contacts [, , ]. Mutations in human VPS13 proteins (VPS13A-D) cause different diseases such as Chorea-acanthocytosis, Cohen syndrome, Parkinson's disease, and spastic ataxia, respectively which suggests they have different functions [, ].
Protein
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1078  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: true
Publication
First Author: Samaranayake HS
Year: 2011
Journal: Eukaryot Cell
Title: Vacuolar protein sorting protein 13A, TtVPS13A, localizes to the tetrahymena thermophila phagosome membrane and is required for efficient phagocytosis.
Volume: 10
Issue: 9
Pages: 1207-18
Protein Domain
Type: Family
Description: Vacuolar protein sorting-associated protein 13 (VPS13) is involved in the delivery of proteins to the vacuole in vegetatively growing yeast []and also regulates membrane morphogenesis during sporulation [, ]. It mediates the transfer of lipids between membranes at organelle contact sites []and it is involved in mitochondrial lipid homeostasis [, ]. In humans, the hereditary disorders chorea acanthocytosis and Cohen syndrome are caused by mutations in members ofthis family that are orthologues of yeast VPS13 (VPS13A and VPS13B respectively). Human VPS13A binds phospholipids and is required for the formation or stabilization of ER-mitochondria contact sites which enable transfer of lipids between the ER and mitochondria [, , ]. It is also required for efficient lysosomal protein degradation [].
Protein
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
Publication
First Author: Velayos-Baeza A
Year: 2004
Journal: Genomics
Title: Analysis of the human VPS13 gene family.
Volume: 84
Issue: 3
Pages: 536-49
Protein
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 757  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Collec E
Year: 1999
Journal: Immunogenetics
Title: Structure and expression of the mouse homologue of the XK gene.
Volume: 50
Issue: 1-2
Pages: 16-21
Publication
First Author: Stanfield GM
Year: 2000
Journal: Mol Cell
Title: The ced-8 gene controls the timing of programmed cell deaths in C. elegans.
Volume: 5
Issue: 3
Pages: 423-33
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876178
Note: kidney
Specimen Label: UC Davis_1876178
Detected: true
Specimen Num: 10
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876152
Note: kidney
Specimen Label: UC Davis_1876152
Detected: true
Specimen Num: 31
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876190
Specimen Label: UC Davis_1876190
Detected: true
Specimen Num: 20
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876154
Specimen Label: UC Davis_1876154
Detected: true
Specimen Num: 33
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876157
Specimen Label: UC Davis_1876157
Detected: true
Specimen Num: 36
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3666828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876181
Specimen Label: UC Davis_1876181
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3666828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876182
Specimen Label: UC Davis_1876182
Detected: true
Specimen Num: 13
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3666828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876155
Specimen Label: UC Davis_1876155
Detected: true
Specimen Num: 34
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3519728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876176
Specimen Label: UC Davis_1876176
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3519728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876151
Specimen Label: UC Davis_1876151
Detected: true
Specimen Num: 30
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876165
Note: vas deferens
Specimen Label: UC Davis_1876165
Detected: true
Specimen Num: 44
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1898428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876183
Specimen Label: UC Davis_1876183
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876158
Specimen Label: UC Davis_1876158
Detected: true
Specimen Num: 37
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1860128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876143
Specimen Label: UC Davis_1876143
Detected: true
Specimen Num: 22
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876164
Specimen Label: UC Davis_1876164
Detected: true
Specimen Num: 43
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1914628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876153
Specimen Label: UC Davis_1876153
Detected: true
Specimen Num: 32
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1920928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6690982
Age: postnatal adult
Image: UC Davis_1876156
Specimen Label: UC Davis_1876156
Detected: true
Specimen Num: 35
GXD Expression  
Probe: MGI:4424984
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829239
Age: embryonic day 14.5
Image: euxassay_012729_01
Specimen Label: euxassay_012729_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4424984
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829239
Age: embryonic day 14.5
Image: euxassay_012729_02
Specimen Label: euxassay_012729_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4424984
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829239
Age: embryonic day 14.5
Image: euxassay_012729_03
Specimen Label: euxassay_012729_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4424984
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829239
Age: embryonic day 14.5
Image: euxassay_012729_04
Specimen Label: euxassay_012729_04
Detected: true
Specimen Num: 4