Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Transient receptor potential (TRP) channels can be described as tetramers formed by subunits with six transmembrane domains and containing cation-selective pores, which in several cases show high calcium permeability. The molecular architecture of TRP channels is reminiscent ofvoltage-gated channels and comprises six putative transmembrane segments (S1-S6), intracellular N- and C-termini, and a pore-forming reentrant loop between S5 and S6 [].TRP channels represent a superfamily conserved from worms to humans that comprise seven subfamilies []: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin or long TRPs), TRPA (ankyrin, whose only member is Transient receptor potential cation channel subfamily A member 1, TrpA1), TRPP (polycystin), TRPML (mucolipin) and TRPN (Nomp-C homologues), which has a single member that can be found in worms, flies, and zebrafish. TRPs are classified essentially according to their primary amino acid sequence rather than selectivity or ligand affinity, due to their heterogeneous properties and complex regulation.TRP channels are involved in many physiological functions, ranging from pure sensory functions, such as pheromone signalling, taste transduction, nociception, and temperature sensation, over homeostatic functions, such as Ca2+ and Mg2+ reabsorption and osmoregulation, to many other motile functions, such as muscle contraction and vaso-motor control [].The TRPV (vanilloid) subfamily can be divided into two distinct groups. The first, which comprises TrpV1, TrpV2, TrpV3, and TrpV4, with nonselective cation conducting pores, has members which can be activated by temperature as well as chemical stimuli. They are involved in a range of functions including nociception, thermosensing and osmolarity sensing. The second group, which consists of TrpV5 and TrpV6, (also known as epithelial calcium channels 1 and 2), highly calcium selective, are involved in renal Ca2+ absorption/reabsorption [, ].TRPV1 was the first vanilloid receptor identified. It is a nonselective cation channel with a preference for calcium and is activated by noxious stimuli, heat, protons, pH 5.9, and various, mostly obnoxious, natural products []. TRPV1 is predominantly expressed in sensory neurons []and is believed to play a crucial role in temperature sensing and nociception [], qualifying therefore as a molecular target for pain treatment. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
531
|
Fragment?: |
false |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388598 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-12-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7388622 |
Age: |
postnatal day 30 |
Image: |
4D TRPV1 Control |
|
Specimen Label: |
4D TRPV1 Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388598 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-12-02 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7388622 |
Age: |
postnatal day 30 |
Image: |
4D TRPV1 Tlx3 CKO |
Note: |
Expression largely eliminated, but high level expressing neurons still observed. Neurons with low to medium levels of expression unaffected compared to control. |
Specimen Label: |
4D TRPV1 Tlx3 CKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388614 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-12-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667827 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:7388634 |
Age: |
postnatal day 0 |
Image: |
5A TRPV1 Control |
Note: |
Extremely high expression levels of expression in some neurons. |
Specimen Label: |
5A TRPV1 Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388614 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-12-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667827 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:7388634 |
Age: |
postnatal day 0 |
Image: |
5A TRPV1 Tlx3-/- |
Note: |
High level expressing neurons nearly completely eliminated. Medium or low levels of expression in some neurons, unaffected compared to control. |
Specimen Label: |
5A TRPV1 Tlx3-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caterina MJ |
Year: |
2000 |
Journal: |
Science |
Title: |
Impaired nociception and pain sensation in mice lacking the capsaicin receptor. |
Volume: |
288 |
Issue: |
5464 |
Pages: |
306-13 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
839
|
Fragment?: |
false |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484576 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7484627 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5d TRPV1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484576 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7484627 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5a TRPV1 Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484576 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-26 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7484627 |
Age: |
postnatal adult |
|
Note: |
Proportion of expressing neurons signficantly decreased compared to control. |
Specimen Label: |
5a TRPV1 PN-ZB20KO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484582 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-05-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7484638 |
Age: |
postnatal adult |
|
|
Specimen Label: |
4 TRPV1 Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484582 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-05-26 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7484638 |
Age: |
postnatal adult |
|
Note: |
Percentage of expressing neurons significantly decreased compared to control. |
Specimen Label: |
4 TRPV1 PN-ZB20KO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tominaga M |
Year: |
1998 |
Journal: |
Neuron |
Title: |
The cloned capsaicin receptor integrates multiple pain-producing stimuli. |
Volume: |
21 |
Issue: |
3 |
Pages: |
531-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caterina MJ |
Year: |
1997 |
Journal: |
Nature |
Title: |
The capsaicin receptor: a heat-activated ion channel in the pain pathway. |
Volume: |
389 |
Issue: |
6653 |
Pages: |
816-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roman K |
Year: |
2020 |
Journal: |
Prostate |
Title: |
TRPV1 in experimental autoimmune prostatitis. |
Volume: |
80 |
Issue: |
1 |
Pages: |
28-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Phan TX |
Year: |
2016 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Sex-dependent expression of TRPV1 in bladder arterioles. |
Volume: |
311 |
Issue: |
5 |
Pages: |
F1063-F1073 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
474
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
471
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
779
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
839
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Vriens J |
Year: |
2009 |
Journal: |
Mol Pharmacol |
Title: |
Pharmacology of vanilloid transient receptor potential cation channels. |
Volume: |
75 |
Issue: |
6 |
Pages: |
1262-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Samanta A |
Year: |
2018 |
Journal: |
Subcell Biochem |
Title: |
Transient Receptor Potential (TRP) Channels. |
Volume: |
87 |
|
Pages: |
141-165 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gaudet R |
Year: |
2008 |
Journal: |
J Physiol |
Title: |
TRP channels entering the structural era. |
Volume: |
586 |
Issue: |
15 |
Pages: |
3565-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Latorre R |
Year: |
2009 |
Journal: |
Q Rev Biophys |
Title: |
Structure-functional intimacies of transient receptor potential channels. |
Volume: |
42 |
Issue: |
3 |
Pages: |
201-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gees M |
Year: |
2010 |
Journal: |
Cold Spring Harb Perspect Biol |
Title: |
The role of transient receptor potential cation channels in Ca2+ signaling. |
Volume: |
2 |
Issue: |
10 |
Pages: |
a003962 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hanack C |
Year: |
2015 |
Journal: |
Cell |
Title: |
GABA blocks pathological but not acute TRPV1 pain signals. |
Volume: |
160 |
Issue: |
4 |
Pages: |
759-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jia YF |
Year: |
2015 |
Journal: |
Front Cell Neurosci |
Title: |
Interference of TRPV1 function altered the susceptibility of PTZ-induced seizures. |
Volume: |
9 |
|
Pages: |
20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Basso L |
Year: |
2019 |
Journal: |
Sci Signal |
Title: |
TRPV1 promotes opioid analgesia during inflammation. |
Volume: |
12 |
Issue: |
575 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Poitras T |
Year: |
2019 |
Journal: |
Mol Neurobiol |
Title: |
Selective Sensory Axon Reinnervation and TRPV1 Activation. |
Volume: |
56 |
Issue: |
10 |
Pages: |
7144-7158 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tian YH |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Blockade of TRPV1 Inhibits Methamphetamine-induced Rewarding Effects. |
Volume: |
8 |
Issue: |
1 |
Pages: |
882 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang SE |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
TRPV1 Regulates Stress Responses through HDAC2. |
Volume: |
19 |
Issue: |
2 |
Pages: |
401-412 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alter BJ |
Year: |
2008 |
Journal: |
Neuron |
Title: |
Hotheaded: TRPV1 as mediator of hippocampal synaptic plasticity. |
Volume: |
57 |
Issue: |
5 |
Pages: |
629-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stemkowski P |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
TRPV1 Nociceptor Activity Initiates USP5/T-type Channel-Mediated Plasticity. |
Volume: |
17 |
Issue: |
11 |
Pages: |
2901-2912 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sondermann JR |
Year: |
2019 |
Journal: |
Pain |
Title: |
Vti1b promotes TRPV1 sensitization during inflammatory pain. |
Volume: |
160 |
Issue: |
2 |
Pages: |
508-527 |
|
•
•
•
•
•
|
Publication |
First Author: |
Page AJ |
Year: |
2019 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
The TRPV1 channel regulates glucose metabolism. |
Volume: |
317 |
Issue: |
4 |
Pages: |
E667-E676 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhong B |
Year: |
2019 |
Journal: |
In Vivo |
Title: |
TRPV1 Mediates Glucose-induced Insulin Secretion Through Releasing Neuropeptides. |
Volume: |
33 |
Issue: |
5 |
Pages: |
1431-1437 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chung MK |
Year: |
2008 |
Journal: |
Nat Neurosci |
Title: |
TRPV1 shows dynamic ionic selectivity during agonist stimulation. |
Volume: |
11 |
Issue: |
5 |
Pages: |
555-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Christoph T |
Year: |
2008 |
Journal: |
Mol Cell Neurosci |
Title: |
Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice. |
Volume: |
37 |
Issue: |
3 |
Pages: |
579-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGrady NR |
Year: |
2020 |
Journal: |
Front Physiol |
Title: |
TRPV1 Tunes Optic Nerve Axon Excitability in Glaucoma. |
Volume: |
11 |
|
Pages: |
249 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu J |
Year: |
2021 |
Journal: |
EMBO Rep |
Title: |
TRPV1 sustains microglial metabolic reprogramming in Alzheimer's disease. |
Volume: |
22 |
Issue: |
6 |
Pages: |
e52013 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao Y |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
TRPV1 SUMOylation suppresses itch by inhibiting TRPV1 interaction with H1 receptors. |
Volume: |
39 |
Issue: |
11 |
Pages: |
110972 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gibson HE |
Year: |
2008 |
Journal: |
Neuron |
Title: |
TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons. |
Volume: |
57 |
Issue: |
5 |
Pages: |
746-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yin S |
Year: |
2013 |
Journal: |
J Clin Invest |
Title: |
Retinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivity. |
Volume: |
123 |
Issue: |
9 |
Pages: |
3941-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Riera CE |
Year: |
2014 |
Journal: |
Cell |
Title: |
TRPV1 pain receptors regulate longevity and metabolism by neuropeptide signaling. |
Volume: |
157 |
Issue: |
5 |
Pages: |
1023-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo L |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Molecular basis for heat desensitization of TRPV1 ion channels. |
Volume: |
10 |
Issue: |
1 |
Pages: |
2134 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paltser G |
Year: |
2013 |
Journal: |
Mol Med |
Title: |
TRPV1 gates tissue access and sustains pathogenicity in autoimmune encephalitis. |
Volume: |
19 |
|
Pages: |
149-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo J |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Zinc Inhibits TRPV1 to Alleviate Chemotherapy-Induced Neuropathic Pain. |
Volume: |
38 |
Issue: |
2 |
Pages: |
474-483 |
|
•
•
•
•
•
|
Publication |
First Author: |
Min H |
Year: |
2014 |
Journal: |
Mol Brain |
Title: |
TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity. |
Volume: |
7 |
|
Pages: |
59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain. |
Volume: |
9 |
Issue: |
1 |
Pages: |
1529 |
|
•
•
•
•
•
|
Publication |
First Author: |
Woodbury CJ |
Year: |
2004 |
Journal: |
J Neurosci |
Title: |
Nociceptors lacking TRPV1 and TRPV2 have normal heat responses. |
Volume: |
24 |
Issue: |
28 |
Pages: |
6410-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rong W |
Year: |
2004 |
Journal: |
J Physiol |
Title: |
Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice. |
Volume: |
560 |
Issue: |
Pt 3 |
Pages: |
867-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen L |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Role of TRPV1 channels in ischemia/reperfusion-induced acute kidney injury. |
Volume: |
9 |
Issue: |
10 |
Pages: |
e109842 |
|
•
•
•
•
•
|
Publication |
First Author: |
Risner ML |
Year: |
2020 |
Journal: |
Front Cell Neurosci |
Title: |
TRPV1 Supports Axogenic Enhanced Excitability in Response to Neurodegenerative Stress. |
Volume: |
14 |
|
Pages: |
603419 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duo L |
Year: |
2018 |
Journal: |
Mol Pain |
Title: |
TRPV1 gain-of-function mutation impairs pain and itch sensations in mice. |
Volume: |
14 |
|
Pages: |
1744806918762031 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koo JY |
Year: |
2007 |
Journal: |
Eur J Neurosci |
Title: |
Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons. |
Volume: |
26 |
Issue: |
5 |
Pages: |
1139-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tykocki NR |
Year: |
2018 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Development of stress-induced bladder insufficiency requires functional TRPV1 channels. |
Volume: |
315 |
Issue: |
6 |
Pages: |
F1583-F1591 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2021 |
Journal: |
Cell Death Dis |
Title: |
TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia. |
Volume: |
12 |
Issue: |
12 |
Pages: |
1159 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okada Y |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
TRPV1 involvement in inflammatory tissue fibrosis in mice. |
Volume: |
178 |
Issue: |
6 |
Pages: |
2654-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Daly D |
Year: |
2007 |
Journal: |
J Physiol |
Title: |
Bladder afferent sensitivity in wild-type and TRPV1 knockout mice. |
Volume: |
583 |
Issue: |
Pt 2 |
Pages: |
663-74 |
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•
•
•
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Publication |
First Author: |
Joseph J |
Year: |
2019 |
Journal: |
J Neurosci |
Title: |
Phosphorylation of TRPV1 S801 Contributes to Modality-Specific Hyperalgesia in Mice. |
Volume: |
39 |
Issue: |
50 |
Pages: |
9954-9966 |
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•
•
•
•
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Publication |
First Author: |
Cremin M |
Year: |
2023 |
Journal: |
PLoS Pathog |
Title: |
TRPV1 controls innate immunity during Citrobacter rodentium enteric infection. |
Volume: |
19 |
Issue: |
12 |
Pages: |
e1011576 |
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•
•
•
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Publication |
First Author: |
Li F |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
TRPV1 activity and substance P release are required for corneal cold nociception. |
Volume: |
10 |
Issue: |
1 |
Pages: |
5678 |
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•
•
•
•
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Publication |
First Author: |
Bertin S |
Year: |
2014 |
Journal: |
Nat Immunol |
Title: |
The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4⁺ T cells. |
Volume: |
15 |
Issue: |
11 |
Pages: |
1055-1063 |
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•
•
•
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Publication |
First Author: |
Roberts JC |
Year: |
2004 |
Journal: |
Brain Res |
Title: |
[3H]Resiniferatoxin autoradiography in the CNS of wild-type and TRPV1 null mice defines TRPV1 (VR-1) protein distribution. |
Volume: |
995 |
Issue: |
2 |
Pages: |
176-83 |
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•
•
•
•
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Publication |
First Author: |
Christoph T |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Investigation of TRPV1 loss-of-function phenotypes in TRPV1 Leu206Stop mice generated by N-ethyl-N-nitrosourea mutagenesis. |
Volume: |
500 |
Issue: |
2 |
Pages: |
456-461 |
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•
•
•
•
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Publication |
First Author: |
Hurtado-Zavala JI |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus. |
Volume: |
8 |
|
Pages: |
15878 |
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•
•
•
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Publication |
First Author: |
Musella A |
Year: |
2009 |
Journal: |
Mol Cell Neurosci |
Title: |
TRPV1 channels facilitate glutamate transmission in the striatum. |
Volume: |
40 |
Issue: |
1 |
Pages: |
89-97 |
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•
•
•
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Publication |
First Author: |
Miyamoto T |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice. |
Volume: |
4 |
Issue: |
10 |
Pages: |
e7596 |
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•
•
•
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Publication |
First Author: |
Miyazaki A |
Year: |
2015 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Integrin α6β4 and TRPV1 channel coordinately regulate directional keratinocyte migration. |
Volume: |
458 |
Issue: |
1 |
Pages: |
161-7 |
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•
•
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•
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Publication |
First Author: |
Lagerström MC |
Year: |
2010 |
Journal: |
Neuron |
Title: |
VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch. |
Volume: |
68 |
Issue: |
3 |
Pages: |
529-42 |
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Publication |
First Author: |
Ciardo MG |
Year: |
2016 |
Journal: |
Biochim Biophys Acta |
Title: |
Whirlin increases TRPV1 channel expression and cellular stability. |
Volume: |
1863 |
Issue: |
1 |
Pages: |
115-27 |
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•
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Publication |
First Author: |
Ma L |
Year: |
2011 |
Journal: |
Cardiovasc Res |
Title: |
Activation of TRPV1 reduces vascular lipid accumulation and attenuates atherosclerosis. |
Volume: |
92 |
Issue: |
3 |
Pages: |
504-13 |
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•
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GXD Expression |
Probe: |
MGI:6185909 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6191514 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Trpv1 |
Detected: |
true |
Specimen Num: |
2 |
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•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185909 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6191514 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Trpv1 |
Detected: |
true |
Specimen Num: |
3 |
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•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185909 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191514 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Trpv1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185909 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191514 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Trpv1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185909 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
|
Stage: |
TS19 |
Assay Id: |
MGI:6191514 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Trpv1 |
Detected: |
false |
Specimen Num: |
1 |
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•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185909 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6191514 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Trpv1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6185909 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191514 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Trpv1 |
Detected: |
true |
Specimen Num: |
7 |
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•
•
•
•
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Publication |
First Author: |
Lin SH |
Year: |
2017 |
Journal: |
J Invest Dermatol |
Title: |
Involvement of TRPV1 and TDAG8 in Pruriception Associated with Noxious Acidosis. |
Volume: |
137 |
Issue: |
1 |
Pages: |
170-178 |
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•
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•
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Publication |
First Author: |
Lapointe TK |
Year: |
2015 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
TRPV1 sensitization mediates postinflammatory visceral pain following acute colitis. |
Volume: |
309 |
Issue: |
2 |
Pages: |
G87-99 |
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•
•
•
•
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Publication |
First Author: |
Stein AT |
Year: |
2006 |
Journal: |
J Gen Physiol |
Title: |
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. |
Volume: |
128 |
Issue: |
5 |
Pages: |
509-22 |
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•
•
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Publication |
First Author: |
Ohanyan VA |
Year: |
2011 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Endothelin-mediated in vivo pressor responses following TRPV1 activation. |
Volume: |
301 |
Issue: |
3 |
Pages: |
H1135-42 |
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•
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Publication |
First Author: |
Patil MJ |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
Sensitization of small-diameter sensory neurons is controlled by TRPV1 and TRPA1 association. |
Volume: |
34 |
Issue: |
1 |
Pages: |
287-302 |
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•
•
•
•
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Publication |
First Author: |
Mallet C |
Year: |
2010 |
Journal: |
PLoS One |
Title: |
TRPV1 in brain is involved in acetaminophen-induced antinociception. |
Volume: |
5 |
Issue: |
9 |
|
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•
•
•
•
•
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Publication |
First Author: |
Wang C |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels. |
Volume: |
279 |
Issue: |
36 |
Pages: |
37423-30 |
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•
•
•
•
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Publication |
First Author: |
Sharif Naeini R |
Year: |
2006 |
Journal: |
Nat Neurosci |
Title: |
An N-terminal variant of Trpv1 channel is required for osmosensory transduction. |
Volume: |
9 |
Issue: |
1 |
Pages: |
93-8 |
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•
•
•
•
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Publication |
First Author: |
Chávez AE |
Year: |
2010 |
Journal: |
Nat Neurosci |
Title: |
TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus. |
Volume: |
13 |
Issue: |
12 |
Pages: |
1511-8 |
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•
•
•
•
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Publication |
First Author: |
Yang D |
Year: |
2010 |
Journal: |
Cell Metab |
Title: |
Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension. |
Volume: |
12 |
Issue: |
2 |
Pages: |
130-41 |
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