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Search results 301 to 400 out of 415 for Lrig1

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Type Details Score
GXD Expression
Probe: MGI:3724371
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421031
Age: embryonic day 14.5
Image: MH431; Specimen C1079
Note: Expression was weak in whisker follicle.
Specimen Label: MH431; Specimen C1079
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6822345
Assay Type: Immunohistochemistry
Annotation Date: 2021-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3787728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6822350
Age: postnatal day 20
Note: Expression is seen in stem cells of the upper isthmus.
Specimen Label: 1I
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6822345
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3787728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7443158
Age: postnatal adult
Image: 1B/D
Note: Expression is seen in the upper isthmus.
Specimen Label: 1B/D
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6822345
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3787728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7443158
Age: postnatal adult
Image: 1H
Specimen Label: 1H
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6822345
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3787728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7443158
Age: postnatal adult
Image: 1I
Specimen Label: 1I
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3724371
Assay Type: RNA in situ
Annotation Date: 2019-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3806722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6381391
Age: embryonic day 14.5
Image: 1C55
Specimen Label: 1C55
Detected: true
Specimen Num: 1
Publication
First Author: Driskell RR
Year: 2013
Journal: Nature
Title: Distinct fibroblast lineages determine dermal architecture in skin development and repair.
Volume: 504
Issue: 7479
Pages: 277-281
Publication
First Author: Suzuki Y
Year: 1996
Journal: J Biol Chem
Title: cDNA cloning of a novel membrane glycoprotein that is expressed specifically in glial cells in the mouse brain. LIG-1, a protein with leucine-rich repeats and immunoglobulin-like domains.
Volume: 271
Issue: 37
Pages: 22522-7
Publication
First Author: Lim SBH
Year: 2023
Journal: Sci Rep
Title: Lrig1-expressing epidermal progenitors require SCD1 to maintain the dermal papilla niche.
Volume: 13
Issue: 1
Pages: 4027
Publication      
First Author: Lim SBH
Year: 2022
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Conditional Scd1 Allele Activated in Hair Follicles
Publication
First Author: Swanson JB
Year: 2019
Journal: Exp Dermatol
Title: Loss of Gata6 causes dilation of the hair follicle canal and sebaceous duct.
Volume: 28
Issue: 4
Pages: 345-349
Publication
First Author: Choi E
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: Active Kras Expression in Gastric Isthmal Progenitor Cells Induces Foveolar Hyperplasia but Not Metaplasia.
Volume: 7
Issue: 1
Pages: 251-253.e1
Publication
First Author: Herring CA
Year: 2018
Journal: Cell Syst
Title: Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut.
Volume: 6
Issue: 1
Pages: 37-51.e9
Publication
First Author: Powell AE
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.
Volume: 307
Issue: 1
Pages: G16-23
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication  
First Author: Pilat JM
Year: 2023
Journal: J Clin Invest
Title: SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions.
Volume: 133
Issue: 13
Publication
First Author: Bensard CL
Year: 2020
Journal: Cell Metab
Title: Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier.
Volume: 31
Issue: 2
Pages: 284-300.e7
Publication      
First Author: Thompson JJ
Year: 2019
Journal: Carcinogenesis
Title: Blood vessel epicardial substance (BVES) reduces LRP6 receptor and cytoplasmic -catenin levels to modulate Wnt signaling and intestinal homeostasis.
Publication
First Author: Means AL
Year: 2018
Journal: Cell Mol Gastroenterol Hepatol
Title: Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer.
Volume: 6
Issue: 3
Pages: 257-276
Publication
First Author: Barbieri AM
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis.
Volume: 96
Issue: 19
Pages: 10729-34
Publication
First Author: Trieu KG
Year: 2022
Journal: Cell Rep
Title: Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease.
Volume: 39
Issue: 5
Pages: 110779
Publication
First Author: Jones KB
Year: 2019
Journal: Cell Stem Cell
Title: Quantitative Clonal Analysis and Single-Cell Transcriptomics Reveal Division Kinetics, Hierarchy, and Fate of Oral Epithelial Progenitor Cells.
Volume: 24
Issue: 1
Pages: 183-192.e8
Publication
First Author: Zhang Q
Year: 2019
Journal: Cell Rep
Title: Transfer of Functional Cargo in Exomeres.
Volume: 27
Issue: 3
Pages: 940-954.e6
Publication
First Author: Kodama T
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM.
Volume: 116
Issue: 47
Pages: 23625-23635
Publication
First Author: Marincola Smith P
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice.
Volume: 320
Issue: 6
Pages: G936-G957
Publication
First Author: Vázquez-Arreguín K
Year: 2019
Journal: PLoS Genet
Title: Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy.
Volume: 15
Issue: 5
Pages: e1007687
Publication
First Author: Veniaminova NA
Year: 2019
Journal: Dev Cell
Title: Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin.
Volume: 51
Issue: 3
Pages: 326-340.e4
Publication
First Author: Choi E
Year: 2015
Journal: Am J Pathol
Title: Dynamic expansion of gastric mucosal doublecortin-like kinase 1-expressing cells in response to parietal cell loss is regulated by gastrin.
Volume: 185
Issue: 8
Pages: 2219-31
Publication
First Author: Sakamoto K
Year: 2021
Journal: Immunity
Title: Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction.
Volume: 54
Issue: 10
Pages: 2321-2337.e10
Publication
First Author: Eberl M
Year: 2018
Journal: Cancer Cell
Title: Tumor Architecture and Notch Signaling Modulate Drug Response in Basal Cell Carcinoma.
Volume: 33
Issue: 2
Pages: 229-243.e4
Publication
First Author: van Erp S
Year: 2015
Journal: Dev Cell
Title: Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.
Volume: 35
Issue: 5
Pages: 537-52
Publication
First Author: Snippert HJ
Year: 2010
Journal: Science
Title: Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.
Volume: 327
Issue: 5971
Pages: 1385-9
Publication
First Author: Abraira VE
Year: 2008
Journal: Development
Title: Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear.
Volume: 135
Issue: 24
Pages: 4091-9
Publication
First Author: Sharir A
Year: 2019
Journal: Nat Cell Biol
Title: A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage.
Volume: 21
Issue: 9
Pages: 1102-1112
Publication
First Author: Peterson SC
Year: 2015
Journal: Cell Stem Cell
Title: Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches.
Volume: 16
Issue: 4
Pages: 400-12
Publication
First Author: Takeda N
Year: 2013
Journal: Development
Title: Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells.
Volume: 140
Issue: 8
Pages: 1655-64
Publication
First Author: Das S
Year: 2015
Journal: Development
Title: Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche.
Volume: 142
Issue: 12
Pages: 2147-62
Publication  
First Author: Oulès B
Year: 2019
Journal: EMBO J
Title: Mutant Lef1 controls Gata6 in sebaceous gland development and cancer.
Volume: 38
Issue: 9
Publication
First Author: López-Arribillaga E
Year: 2015
Journal: Development
Title: Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch.
Volume: 142
Issue: 1
Pages: 41-50
Publication
First Author: Lee B
Year: 2014
Journal: Dev Cell
Title: Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells.
Volume: 29
Issue: 1
Pages: 47-58
Publication
First Author: Cheung P
Year: 2020
Journal: Cell Stem Cell
Title: Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer.
Volume: 27
Issue: 4
Pages: 590-604.e9
Publication
First Author: Veniaminova NA
Year: 2013
Journal: Development
Title: Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration.
Volume: 140
Issue: 24
Pages: 4870-80
Publication
First Author: Lewis AE
Year: 2022
Journal: Cell Rep
Title: Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting.
Volume: 38
Issue: 11
Pages: 110510
Publication
First Author: DiTommaso T
Year: 2014
Journal: PLoS Genet
Title: Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.
Volume: 10
Issue: 10
Pages: e1004705
Publication
First Author: Yui S
Year: 2018
Journal: Cell Stem Cell
Title: YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration.
Volume: 22
Issue: 1
Pages: 35-49.e7
Publication
First Author: Maimets M
Year: 2022
Journal: Nat Commun
Title: Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling.
Volume: 13
Issue: 1
Pages: 715
Publication
First Author: Homma S
Year: 2009
Journal: Gene Expr Patterns
Title: Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.
Volume: 9
Issue: 1
Pages: 1-26
Publication
First Author: Yang YP
Year: 2017
Journal: Cell Rep
Title: A Chimeric Egfr Protein Reporter Mouse Reveals Egfr Localization and Trafficking In Vivo.
Volume: 19
Issue: 6
Pages: 1257-1267
Publication
First Author: Kechele DO
Year: 2017
Journal: J Clin Invest
Title: Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation.
Volume: 127
Issue: 2
Pages: 593-607
Publication
First Author: Sotiropoulou PA
Year: 2013
Journal: Genes Dev
Title: BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.
Volume: 27
Issue: 1
Pages: 39-51
Publication    
First Author: Kuwahara A
Year: 2020
Journal: Elife
Title: Delineating the early transcriptional specification of the mammalian trachea and esophagus.
Volume: 9
Publication
First Author: van der Weyden L
Year: 2020
Journal: G3 (Bethesda)
Title: A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation.
Volume: 10
Issue: 6
Pages: 1869-1877
Publication
First Author: Adissu HA
Year: 2014
Journal: Dis Model Mech
Title: Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.
Volume: 7
Issue: 5
Pages: 515-24
Publication  
First Author: Liakath-Ali K
Year: 2014
Journal: Nat Commun
Title: Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.
Volume: 5
Pages: 3540
Publication
First Author: Zhang Y
Year: 2008
Journal: Development
Title: Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.
Volume: 135
Issue: 12
Pages: 2161-72
Publication
First Author: Gu Z
Year: 2015
Journal: PLoS One
Title: Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Volume: 10
Issue: 3
Pages: e0121550
Publication      
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
Publication
First Author: Tamplin OJ
Year: 2011
Journal: Dev Biol
Title: Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.
Volume: 360
Issue: 2
Pages: 415-25
Publication
First Author: Gurdziel K
Year: 2016
Journal: Dev Dyn
Title: Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.
Volume: 245
Issue: 5
Pages: 614-26
Publication  
First Author: Ahuja N
Year: 2022
Journal: Dev Biol
Title: Endothelial Cyp26b1 restrains murine heart valve growth during development.
Volume: 486
Pages: 81-95
Publication
First Author: Neidhardt L
Year: 2000
Journal: Mech Dev
Title: Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.
Volume: 98
Issue: 1-2
Pages: 77-94
Publication      
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
Publication
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Li Q
Year: 2019
Journal: Nat Commun
Title: LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer.
Volume: 10
Issue: 1
Pages: 5494
Publication
First Author: Laederich MB
Year: 2004
Journal: J Biol Chem
Title: The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases.
Volume: 279
Issue: 45
Pages: 47050-6
Allele
Name: leucine-rich repeats and immunoglobulin-like domains 1; targeted mutation 1, Kim B Jensen
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Genotype
Symbol: Lrig1/Lrig1<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Lrig1/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Allele
Name: transgene insertion KP321, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: mutant stock, transgenic