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Search results 301 to 317 out of 317 for Dnm1l

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Type Details Score
DO Term
DOID:0111438 | optic atrophy 5
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Publication
23921378 | -
First Author: Palmer CS
Year: 2013
Journal: J Biol Chem
Title: Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.
Volume: 288
Issue: 38
Pages: 27584-93
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Protein
A0A2U3TZF4
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: false
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Publication
21508961 | -
First Author: Palmer CS
Year: 2011
Journal: EMBO Rep
Title: MiD49 and MiD51, new components of the mitochondrial fission machinery.
Volume: 12
Issue: 6
Pages: 565-73
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Publication
29361167 | -
First Author: Bartsakoulia M
Year: 2018
Journal: Hum Mol Genet
Title: A novel mechanism causing imbalance of mitochondrial fusion and fission in human myopathies.
Volume: 27
Issue: 7
Pages: 1186-1195
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Publication
29431643 | -
First Author: Chen KH
Year: 2018
Journal: Circulation
Title: Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
Volume: 138
Issue: 3
Pages: 287-304
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Publication
29899447 | -
First Author: Kalia R
Year: 2018
Journal: Nature
Title: Structural basis of mitochondrial receptor binding and constriction by DRP1.
Volume: 558
Issue: 7710
Pages: 401-405
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Protein Domain
IPR045909 | MID49/MID51
Type: Family
Description: This entry represents the mitochondrial dynamics protein MID49/MID51. Most members of this protein family contain a Mab-21 domain and are found in chordates.In humans, MID49 and MID51 are outer membrane proteins involved in the regulation of mitochondrial organisation and required for mitochondrial fission by promoting the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. They also regulate DNM1L GTPase activity [, , , , ]. Deregulation of these proteins has been linked to human diseases such as pulmonary arterial hypertension [].
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HT Experiment
GSE248081 | Drp1 Controls Complex II assembly and Fatty Acid Oxidation by Sdhaf2 Action on Mitochondria
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
Q5NCS9
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Protein
Q8BGV8
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: false
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Protein
B2RPW2
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: false
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Protein
Q3TB59
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
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Publication
26611103 | J:258697
 
First Author: Fields JA
Year: 2016
Journal: Neurobiol Dis
Title: HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders.
Volume: 86
Pages: 154-69
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Publication
33836591 | J:303260
 
First Author: Park YJ
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics.
Volume: 118
Issue: 11
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Publication
33970775 | J:314300
First Author: Nie T
Year: 2021
Journal: Autophagy
Title: Chaperone-mediated autophagy controls the turnover of E3 ubiquitin ligase MARCHF5 and regulates mitochondrial dynamics.
Volume: 17
Issue: 10
Pages: 2923-2938
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Publication
33300446 | J:302667
   
First Author: Liu H
Year: 2020
Journal: Autophagy
Title: Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2R1441G mice.
Pages: 1-25
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