|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 601 to 700 out of 744 for Zic2

<< First    < Previous  |  Next >    Last >>
0.04s

Categories

Hits by Strain

Hits by Category

Type Details Score
Publication
15736266 | J:97076
First Author: Furushima K
Year: 2005
Journal: Dev Dyn
Title: Characterization of Opr deficiency in mouse brain: subtle defects in dorsomedial telencephalon and medioventral forebrain.
Volume: 232
Issue: 4
Pages: 1056-61
•
•
•
•
•
Publication
28137836 | J:240943
First Author: Bruce FM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: DSCAM promotes axon fasciculation and growth in the developing optic pathway.
Volume: 114
Issue: 7
Pages: 1702-1707
•
•
•
•
•
Publication
10409504 | J:54722
First Author: Engelkamp D
Year: 1999
Journal: Development
Title: Role of Pax6 in development of the cerebellar system.
Volume: 126
Issue: 16
Pages: 3585-96
•
•
•
•
•
Publication
30149005 | J:266267
First Author: Clements R
Year: 2018
Journal: Dev Biol
Title: Retinal ganglion cell axon sorting at the optic chiasm requires dystroglycan.
Volume: 442
Issue: 2
Pages: 210-219
•
•
•
•
•
Publication
18547559 | J:139160
First Author: Okada T
Year: 2008
Journal: Dev Biol
Title: FGF8 signaling patterns the telencephalic midline by regulating putative key factors of midline development.
Volume: 320
Issue: 1
Pages: 92-101
•
•
•
•
•
Publication
16701205 | J:122943
First Author: Williams SE
Year: 2006
Journal: Neuron
Title: A role for Nr-CAM in the patterning of binocular visual pathways.
Volume: 50
Issue: 4
Pages: 535-47
•
•
•
•
•
Publication
28215559 | J:256120
First Author: Kuwajima T
Year: 2017
Journal: Neuron
Title: SoxC Transcription Factors Promote Contralateral Retinal Ganglion Cell Differentiation and Axon Guidance in the Mouse Visual System.
Volume: 93
Issue: 5
Pages: 1110-1125.e5
•
•
•
•
•
Publication
16354917 | J:123264
First Author: Quina LA
Year: 2005
Journal: J Neurosci
Title: Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways.
Volume: 25
Issue: 50
Pages: 11595-604
•
•
•
•
•
Publication
11455436 | J:69868
First Author: Spörle R
Year: 2001
Journal: Dev Genes Evol
Title: Epaxial-adaxial-hypaxial regionalisation of the vertebrate somite: evidence for a somitic organiser and a mirror-image duplication.
Volume: 211
Issue: 4
Pages: 198-217
•
•
•
•
•
Publication
22623663 | J:184980
First Author: Assimacopoulos S
Year: 2012
Journal: J Neurosci
Title: Fibroblast growth factor 8 organizes the neocortical area map and regulates sensory map topography.
Volume: 32
Issue: 21
Pages: 7191-201
•
•
•
•
•
Publication
23606270 | J:198578
First Author: Chervenak AP
Year: 2013
Journal: Dev Dyn
Title: Spatiotemporal expression of Zic genes during vertebrate inner ear development.
Volume: 242
Issue: 7
Pages: 897-908
•
•
•
•
•
Publication
28978771 | J:246054
First Author: Nadeau JH
Year: 2017
Journal: Genetics
Title: Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization.
Volume: 207
Issue: 2
Pages: 369-387
•
•
•
•
•
Publication
10932191 | J:63816
First Author: Nolan PM
Year: 2000
Journal: Nat Genet
Title: A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.
Volume: 25
Issue: 4
Pages: 440-3
•
•
•
•
•
Publication
15384171 | J:93195
First Author: Bogani D
Year: 2004
Journal: Genesis
Title: New semidominant mutations that affect mouse development.
Volume: 40
Issue: 2
Pages: 109-117
•
•
•
•
•
Publication
36351424 | J:332436
First Author: Slavi N
Year: 2023
Journal: Neuron
Title: CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism.
Volume: 111
Issue: 1
Pages: 49-64.e5
•
•
•
•
•
Publication
27097562 | J:237402
First Author: Iwai-Takekoshi L
Year: 2016
Journal: J Comp Neurol
Title: Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.
Volume: 524
Issue: 18
Pages: 3696-3716
•
•
•
•
•
Publication
31869353 | J:283382
First Author: Qin L
Year: 2019
Journal: PLoS One
Title: Analyses with double knockouts of the Bmpr1a and Bmpr1b genes demonstrate that BMP signaling is involved in the formation of precerebellar mossy fiber nuclei derived from the rhombic lip.
Volume: 14
Issue: 12
Pages: e0226602
•
•
•
•
•
Publication
22578469 | J:186443
 
First Author: MĂĽller Smith K
Year: 2012
Journal: Brain Res
Title: Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice.
Volume: 1460
Pages: 12-24
•
•
•
•
•
Publication
33492553 | J:304355
First Author: Garcia-Calero E
Year: 2021
Journal: Brain Struct Funct
Title: Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala.
Volume: 226
Issue: 2
Pages: 519-562
•
•
•
•
•
Publication
10693795 | J:60594
First Author: Lee KJ
Year: 2000
Journal: Nature
Title: Genetic ablation reveals that the roof plate is essential for dorsal interneuron specification.
Volume: 403
Issue: 6771
Pages: 734-40
•
•
•
•
•
Publication
17360405 | J:120058
First Author: Pascual M
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression.
Volume: 104
Issue: 12
Pages: 5193-8
•
•
•
•
•
Publication
22632726 | J:188362
First Author: Kuwajima T
Year: 2012
Journal: Neuron
Title: Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.
Volume: 74
Issue: 4
Pages: 676-90
•
•
•
•
•
Publication
15799026 | J:100371
First Author: Okada A
Year: 2005
Journal: Birth Defects Res A Clin Mol Teratol
Title: Identification of early-responsive genes correlated to valproic acid-induced neural tube defects in mice.
Volume: 73
Issue: 4
Pages: 229-38
•
•
•
•
•
Publication
35231638 | J:336226
First Author: Chen X
Year: 2022
Journal: J Genet Genomics
Title: Deletion of CHD8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia, and psychiatric behavior in mice.
Volume: 49
Issue: 9
Pages: 859-869
•
•
•
•
•
Publication
26439398 | J:239874
First Author: Christ A
Year: 2015
Journal: Dev Cell
Title: LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.
Volume: 35
Issue: 1
Pages: 36-48
•
•
•
•
•
Publication
21658587 | J:174966
First Author: Erskine L
Year: 2011
Journal: Neuron
Title: VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm.
Volume: 70
Issue: 5
Pages: 951-65
•
•
•
•
•
Publication
16855091 | J:110657
First Author: Cheng X
Year: 2006
Journal: J Neurosci
Title: Central roles of the roof plate in telencephalic development and holoprosencephaly.
Volume: 26
Issue: 29
Pages: 7640-9
•
•
•
•
•
Publication
19850029 | J:157031
First Author: Misra K
Year: 2010
Journal: Dev Biol
Title: A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling.
Volume: 337
Issue: 1
Pages: 74-83
•
•
•
•
•
Publication
21273545 | J:171526
First Author: Murali D
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Smad4 is required predominantly in the developmental processes dependent on the BMP branch of the TGF-β signaling system in the embryonic mouse retina.
Volume: 52
Issue: 6
Pages: 2930-7
•
•
•
•
•
Publication
29874580 | J:270927
First Author: Kridsada K
Year: 2018
Journal: Cell Rep
Title: Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons.
Volume: 23
Issue: 10
Pages: 2928-2941
•
•
•
•
•
Publication
29386106 | J:270726
First Author: Shimada IS
Year: 2018
Journal: Cell Rep
Title: Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.
Volume: 22
Issue: 5
Pages: 1169-1184
•
•
•
•
•
Publication
25336744 | J:217604
First Author: Lavado A
Year: 2014
Journal: Development
Title: The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap.
Volume: 141
Issue: 21
Pages: 4182-93
•
•
•
•
•
Publication
12654290 | J:82686
First Author: Liu J
Year: 2003
Journal: Dev Biol
Title: BMP receptor 1b is required for axon guidance and cell survival in the developing retina.
Volume: 256
Issue: 1
Pages: 34-48
•
•
•
•
•
Publication
23595746 | J:196967
First Author: Roy A
Year: 2013
Journal: J Neurosci
Title: LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.
Volume: 33
Issue: 16
Pages: 6877-84
•
•
•
•
•
Publication
33760820 | J:339532
First Author: Li J
Year: 2021
Journal: PLoS Genet
Title: Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.
Volume: 17
Issue: 3
Pages: e1009355
•
•
•
•
•
Publication
23307637 | J:210131
First Author: Roy A
Year: 2014
Journal: Cereb Cortex
Title: Lhx2 regulates the development of the forebrain hem system.
Volume: 24
Issue: 5
Pages: 1361-72
•
•
•
•
•
Publication
35927240 | J:327333
First Author: Yang KY
Year: 2022
Journal: Cell Death Dis
Title: Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.
Volume: 13
Issue: 8
Pages: 674
•
•
•
•
•
Publication
27957530 | J:255944
 
First Author: Wang Q
Year: 2016
Journal: eNeuro
Title: Ipsilateral and Contralateral Retinal Ganglion Cells Express Distinct Genes during Decussation at the Optic Chiasm.
Volume: 3
Issue: 6
•
•
•
•
•
Publication
15229182 | J:92064
First Author: Ding YQ
Year: 2004
Journal: Development
Title: Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.
Volume: 131
Issue: 15
Pages: 3693-703
•
•
•
•
•
Publication
22992956 | J:189004
First Author: Iwafuchi-Doi M
Year: 2012
Journal: Development
Title: Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.
Volume: 139
Issue: 21
Pages: 3926-37
•
•
•
•
•
Publication
34254395 | J:328711
First Author: Fernandez-Guerrero M
Year: 2022
Journal: Dev Dyn
Title: Time-sequenced transcriptomes of developing distal mouse limb buds: A comparative tissue layer analysis.
Volume: 251
Issue: 9
Pages: 1550-1575
•
•
•
•
•
Publication
30254141 | J:272616
 
First Author: Iwai-Takekoshi L
Year: 2018
Journal: Development
Title: Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina.
Volume: 145
Issue: 21
•
•
•
•
•
Publication
36737666 | J:333797
First Author: Min KW
Year: 2023
Journal: Exp Mol Med
Title: Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant.
Volume: 55
Issue: 2
Pages: 385-400
•
•
•
•
•
Publication
15691760 | J:105025
First Author: Cheung M
Year: 2005
Journal: Dev Cell
Title: The transcriptional control of trunk neural crest induction, survival, and delamination.
Volume: 8
Issue: 2
Pages: 179-92
•
•
•
•
•
Publication
19449303 | J:151233
First Author: Trimarchi JM
Year: 2009
Journal: Dev Dyn
Title: Identification of genes expressed preferentially in the developing peripheral margin of the optic cup.
Volume: 238
Issue: 9
Pages: 2327-9
•
•
•
•
•
Publication
22235033 | J:203028
First Author: Hasenpusch-Theil K
Year: 2012
Journal: Cereb Cortex
Title: Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus.
Volume: 22
Issue: 12
Pages: 2878-93
•
•
•
•
•
Publication
37524711 | J:338811
First Author: Qu F
Year: 2023
Journal: Nat Commun
Title: Three-dimensional molecular architecture of mouse organogenesis.
Volume: 14
Issue: 1
Pages: 4599
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
20436479 | J:157819
First Author: Shimogori T
Year: 2010
Journal: Nat Neurosci
Title: A genomic atlas of mouse hypothalamic development.
Volume: 13
Issue: 6
Pages: 767-75
•
•
•
•
•
Publication
16919269 | J:112701
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
•
•
•
•
•
Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
•
•
•
•
•
Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
•
•
•
•
•
Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
•
•
•
•
•
Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
HT Experiment
GSE106350 | ZIC2 Is Required For Nodal Expression And The Establishment Of Left-Sided Identity
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5289047
Assay Type: RT-PCR
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:5823398
Age: embryonic day 7.0
Specimen Label: Zic2 +/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5289047
Assay Type: RT-PCR
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:5823398
Age: embryonic day 7.0
Specimen Label: Zic2 Ku/Ku
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5288877
Assay Type: RT-PCR
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:5823399
Age: embryonic day 7.0
Specimen Label: Zic2 +/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5288877
Assay Type: RT-PCR
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:5823399
Age: embryonic day 7.0
Specimen Label: Zic2 Ku/Ku
Detected: true
Specimen Num: 2
•
•
•
•
•
Genotype
Genotype
Symbol: Zic2/Zic2
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Allele
Zic2<tm1Jaru> | MGI:2156825
Name: zinc finger protein of the cerebellum 2; targeted mutation 1, Jun Aruga
Allele Type: Targeted
Attribute String: Hypomorph
•
•
•
•
•
Allele
Zic2<Ku> | MGI:1862004
 
Name: zinc finger protein of the cerebellum 2; kumba
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Interaction Experiment
Pan H (2011)
Description: A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis.
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Decreasing Nodal function on the Zic2 Ku background leads to moderate or severe truncation.
Specimen Label: 1I
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Decreasing Nodal function on the Zic2 Ku background leads to moderate or severe truncation.
Specimen Label: 1I
Specimen Num: 9
•
•
•
•
•
Genotype
Genotype
Symbol: Zic2/Zic2
Background: C3.CAnNCrl-Zic2
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Zic2/Zic2
Background: 129S.CAnNCrl(C3)-Zic2
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
DO Term
DOID:0110878 | holoprosencephaly 5
•
•
•
•
•
Allele
Zic2<em2Smoc> | MGI:7293260
Name: zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos heterozygous for the severe loss of function kumba (Ku) allele of Zic2 have no discernible phenotype.
Specimen Label: 1D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos heterozygous for the severe loss of function kumba (Ku) allele of Zic2 have no discernible phenotype.
Specimen Label: 1D
Detected: true
Specimen Num: 4
•
•
•
•
•
Allele
Zic2<em1Krc> | MGI:7293294
Name: zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 1, Kenneth R Chien
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Allele
Zic2<em2Krc> | MGI:7293299
Name: zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 2, Kenneth R Chien
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:23226
Assay Type: RNA in situ
Annotation Date: 2017-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5823402
Age: embryonic day 9.5
Note: Embryos homozygous for the severe loss of function kumba (Ku) allele of Zic2 exhibit forebrain dysmorphology that can include a mild loss of telencephalic tissue.
Specimen Label: 1E
Specimen Num: 5
•
•
•
•
•
Publication
15880380 | -
First Author: Vural B
Year: 2005
Journal: Cancer
Title: Frequency of SOX Group B (SOX1, 2, 3) and ZIC2 antibodies in Turkish patients with small cell lung carcinoma and their correlation with clinical parameters.
Volume: 103
Issue: 12
Pages: 2575-83
•
•
•
•
•
Allele
Zic2<em1Smoc> | MGI:7293259
Name: zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom