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Search results 101 to 172 out of 172 for Acy1

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0.023s
Type Details Score
GXD Expression    
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1842522
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Note: Expression was not detected in the endocrine system.
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1706822
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1842622
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610422
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1733122
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274322
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1853522
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752322
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3272922
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Note: Expression was not detected in the skeleton (limbs, shoulder, hip).
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276322
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Note: Expression was not detected in the face/soft tissues.
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1674822
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1745822
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752422
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876922
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310595
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423918
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EH733; Specimen C2466
Detected: false
Specimen Num: 1
Publication      
First Author: Kirn-Safran CB
Year: 2005
Journal: MGI Direct Data Submission
Title: RFLP at the Rpl29 locus on mouse Chromosome 9
Publication  
First Author: Lalley PA
Year: 1982
Journal: Cytogenet Cell Genet
Title: Assignment of Acy-1 to mouse Chromosome 9: evidence for homologous linkage groups in man and mouse.
Volume: 32
Pages: 293-293 (Abstr.)
Publication
First Author: Benson MD
Year: 2023
Journal: Cell Metab
Title: Protein-metabolite association studies identify novel proteomic determinants of metabolite levels in human plasma.
Volume: 35
Issue: 9
Pages: 1646-1660.e3
Publication
First Author: Nadeau JH
Year: 1986
Journal: Genet Res
Title: A chromosomal segment conserved since divergence of lineages leading to man and mouse: the gene order of aminoacylase-1, transferrin, and beta-galactosidase on mouse chromosome 9.
Volume: 48
Issue: 3
Pages: 175-8
Publication
First Author: Antonucci TK
Year: 1984
Journal: Genetics
Title: Conserved linkage within a 4-cM region of mouse chromosome 9 and human chromosome 11.
Volume: 107
Issue: 3
Pages: 463-75
Publication
First Author: Hino O
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Universal mapping probes and the origin of human chromosome 3.
Volume: 90
Issue: 2
Pages: 730-4
Publication
First Author: Araujo DJ
Year: 2015
Journal: Genes Dev
Title: FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.
Volume: 29
Issue: 20
Pages: 2081-96
Publication        
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Sass JO
Year: 2006
Journal: Am J Hum Genet
Title: Mutations in ACY1, the gene encoding aminoacylase 1, cause a novel inborn error of metabolism.
Volume: 78
Issue: 3
Pages: 401-9
Publication
First Author: Kempf B
Year: 1996
Journal: FEMS Microbiol Lett
Title: A novel amidohydrolase gene from Bacillus subtilis cloning: DNA-sequence analysis and map position of amhX.
Volume: 141
Issue: 2-3
Pages: 129-37
Protein Domain
Type: Family
Description: This entry includes Bacillus subtilis AmhX and related proteins that form a subfamily of the peptidase M20 family []. They are predicted amidohydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins []. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine) [].
Publication
First Author: Shridhar V
Year: 1996
Journal: Oncogene
Title: A gene from human chromosomal band 3p21.1 encodes a highly conserved arginine-rich protein and is mutated in renal cell carcinomas.
Volume: 12
Issue: 9
Pages: 1931-9
Publication
First Author: Lindner HA
Year: 2003
Journal: J Biol Chem
Title: Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family.
Volume: 278
Issue: 45
Pages: 44496-504
Publication
First Author: Sawazaki T
Year: 1999
Journal: Cytogenet Cell Genet
Title: The pig aminoacylase 1 (ACY1) and ribosomal protein L29 (RPL29)/heparin/heparan sulfate interacting protein (HIP) genes are located together at 13q21-->q22, corresponding to human 3p21.1.
Volume: 86
Issue: 1
Pages: 56-61
Publication
First Author: Baumeier C
Year: 2015
Journal: Biochim Biophys Acta
Title: Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice.
Volume: 1851
Issue: 5
Pages: 566-76
Publication  
First Author: Threadgill DS
Year: 1989
Journal: Cytogenet Cell Genet
Title: Comparative mapping of HSA 21/MMU 16 homologs in the bovine.
Volume: 51
Pages: 1090-1091 (Abstr.)