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Search results 1 to 100 out of 131 for Chek2

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Category: Publication
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Type Details Score
Publication
37862420 | J:341994
First Author: Emori C
Year: 2023
Journal: Sci Adv
Title: CHEK2 signaling is the key regulator of oocyte survival after chemotherapy.
Volume: 9
Issue: 42
Pages: eadg0898
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Publication
20434834 | J:162668
First Author: Meyer SE
Year: 2010
Journal: Cancer Lett
Title: Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice.
Volume: 296
Issue: 2
Pages: 186-93
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Publication
17174984 | J:118262
First Author: Bahassi el M
Year: 2007
Journal: Mutat Res
Title: The breast cancer susceptibility allele CHEK2*1100delC promotes genomic instability in a knock-in mouse model.
Volume: 616
Issue: 1-2
Pages: 201-9
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Publication
15485917 | J:94114
First Author: Kim SS
Year: 2004
Journal: Mol Cell Biol
Title: Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1.
Volume: 24
Issue: 21
Pages: 9498-507
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Publication
19805189 | J:153668
First Author: Bahassi el M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.
Volume: 106
Issue: 40
Pages: 17111-6
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Publication
36949040 | J:337603
First Author: Dmello C
Year: 2023
Journal: Nat Commun
Title: Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade.
Volume: 14
Issue: 1
Pages: 1566
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Publication
22030621 | J:316428
First Author: Höglund A
Year: 2011
Journal: Cell Cycle
Title: Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition.
Volume: 10
Issue: 20
Pages: 3598-607
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Publication
33200984 | J:299451
   
First Author: Atkins A
Year: 2020
Journal: Elife
Title: SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis.
Volume: 9
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Publication
9836640 | J:61425
First Author: Matsuoka S
Year: 1998
Journal: Science
Title: Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Volume: 282
Issue: 5395
Pages: 1893-7
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Publication
37390209 | J:337800
First Author: Oropeza E
Year: 2023
Journal: Sci Adv
Title: Molecular portraits of cell cycle checkpoint kinases in cancer evolution, progression, and treatment responsiveness.
Volume: 9
Issue: 26
Pages: eadf2860
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Publication
20577265 | J:168164
First Author: Nalapareddy K
Year: 2010
Journal: EMBO Rep
Title: CHK2-independent induction of telomere dysfunction checkpoints in stem and progenitor cells.
Volume: 11
Issue: 8
Pages: 619-25
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Publication
32187724 | J:297245
First Author: Guo QQ
Year: 2020
Journal: EMBO J
Title: ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress.
Volume: 39
Issue: 10
Pages: e103111
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Publication
15950944 | J:99262
First Author: Chen C
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage.
Volume: 333
Issue: 2
Pages: 427-31
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Publication
37943659 | J:343599
First Author: Liu J
Year: 2023
Journal: Cell Rep
Title: ATM-CHK2-TRIM32 axis regulates ATG7 ubiquitination to initiate autophagy under oxidative stress.
Volume: 42
Issue: 11
Pages: 113402
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Publication
18971944 | J:143252
First Author: Chou WC
Year: 2008
Journal: EMBO J
Title: Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair.
Volume: 27
Issue: 23
Pages: 3140-50
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Publication
22006019 | J:178305
First Author: Pines A
Year: 2011
Journal: Mol Cell Biol
Title: Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells.
Volume: 31
Issue: 24
Pages: 4964-77
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Publication
24598997 | J:209346
First Author: Dai XX
Year: 2014
Journal: Mol Cells
Title: Chk2 regulates cell cycle progression during mouse oocyte maturation and early embryo development.
Volume: 37
Issue: 2
Pages: 126-32
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Publication
32993749 | J:311169
First Author: Guo P
Year: 2020
Journal: J Exp Clin Cancer Res
Title: FadA promotes DNA damage and progression of Fusobacterium nucleatum-induced colorectal cancer through up-regulation of chk2.
Volume: 39
Issue: 1
Pages: 202
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Publication
29805302 | J:288589
First Author: Zhang Y
Year: 2018
Journal: Int J Biol Sci
Title: DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide.
Volume: 14
Issue: 5
Pages: 508-517
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Publication
27767095 | J:262094
First Author: Adhikari D
Year: 2016
Journal: Cell Res
Title: Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan.
Volume: 26
Issue: 11
Pages: 1212-1225
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24920220 | J:217323
First Author: García-Beccaria M
Year: 2014
Journal: Aging Cell
Title: In vivo role of checkpoint kinase 2 in signaling telomere dysfunction.
Volume: 13
Issue: 5
Pages: 810-6
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Publication
23449389 | J:228256
First Author: Bohgaki M
Year: 2013
Journal: Cell Death Differ
Title: The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover.
Volume: 20
Issue: 6
Pages: 812-22
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Publication
29859927 | J:270504
First Author: Tanoue Y
Year: 2018
Journal: J Invest Dermatol
Title: Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure.
Volume: 138
Issue: 12
Pages: 2550-2557
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31209362 | J:290678
First Author: Zhang W
Year: 2020
Journal: Cell Death Differ
Title: SIRT1 modulates cell cycle progression by regulating CHK2 acetylation-phosphorylation.
Volume: 27
Issue: 2
Pages: 482-496
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33690219 | J:305920
 
First Author: Xiang J
Year: 2021
Journal: J Clin Invest
Title: Gluconeogenic enzyme PCK1 deficiency promotes CHK2 O-GlcNAcylation and hepatocellular carcinoma growth upon glucose deprivation.
Volume: 131
Issue: 8
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33097538 | J:299008
 
First Author: Powers NR
Year: 2020
Journal: Sci Adv
Title: Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard.
Volume: 6
Issue: 43
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34349265 | J:326210
First Author: Ruth KS
Year: 2021
Journal: Nature
Title: Genetic insights into biological mechanisms governing human ovarian ageing.
Volume: 596
Issue: 7872
Pages: 393-397
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20834228 | J:165429
First Author: Niida H
Year: 2010
Journal: EMBO J
Title: Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo.
Volume: 29
Issue: 20
Pages: 3558-70
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19404261 | J:148536
First Author: Liu J
Year: 2009
Journal: Nature
Title: Bmi1 regulates mitochondrial function and the DNA damage response pathway.
Volume: 459
Issue: 7245
Pages: 387-392
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12356735 | J:88888
First Author: Takai H
Year: 2002
Journal: EMBO J
Title: Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription.
Volume: 21
Issue: 19
Pages: 5195-205
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Publication
17360434 | J:120057
First Author: Zaugg K
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.
Volume: 104
Issue: 10
Pages: 3805-10
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Publication
21791608 | J:175866
First Author: Ullah Z
Year: 2011
Journal: Mol Cell Biol
Title: Checkpoint kinase 1 prevents cell cycle exit linked to terminal cell differentiation.
Volume: 31
Issue: 19
Pages: 4129-43
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21745814 | J:183033
First Author: Yu TX
Year: 2011
Journal: Nucleic Acids Res
Title: Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function.
Volume: 39
Issue: 19
Pages: 8472-87
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15893606 | J:99333
First Author: Matsuki T
Year: 2005
Journal: Brain Res Mol Brain Res
Title: Gene expression profiling during the embryonic development of mouse brain using an oligonucleotide-based microarray system.
Volume: 136
Issue: 1-2
Pages: 231-54
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Publication
22448250 | J:187030
First Author: Chen CH
Year: 2012
Journal: PLoS One
Title: Disruption of murine mp29/Syf2/Ntc31 gene results in embryonic lethality with aberrant checkpoint response.
Volume: 7
Issue: 3
Pages: e33538
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22499945 | J:183932
First Author: Lee IH
Year: 2012
Journal: Science
Title: Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress.
Volume: 336
Issue: 6078
Pages: 225-8
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12192050 | J:78491
First Author: Hirao A
Year: 2002
Journal: Mol Cell Biol
Title: Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.
Volume: 22
Issue: 18
Pages: 6521-32
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15131084 | J:90512
First Author: McPherson JP
Year: 2004
Journal: Genes Dev
Title: Collaboration of Brca1 and Chk2 in tumorigenesis.
Volume: 18
Issue: 10
Pages: 1144-53
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28844861 | J:253200
First Author: Rinaldi VD
Year: 2017
Journal: Mol Cell
Title: The DNA Damage Checkpoint Eliminates Mouse Oocytes with Chromosome Synapsis Failure.
Volume: 67
Issue: 6
Pages: 1026-1036.e2
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12097646 | J:126186
First Author: Jack MT
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response.
Volume: 99
Issue: 15
Pages: 9825-9
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Publication
18086870 | J:131583
First Author: Zheng L
Year: 2008
Journal: Blood
Title: TLR9 engagement on CD4 T lymphocytes represses gamma-radiation-induced apoptosis through activation of checkpoint kinase response elements.
Volume: 111
Issue: 5
Pages: 2704-13
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30305635 | J:268570
First Author: Abreu CM
Year: 2018
Journal: Nat Commun
Title: Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination.
Volume: 9
Issue: 1
Pages: 3961
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33484913 | J:314024
First Author: Buitrago-Molina LE
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: p53-Independent Induction of p21 Fails to Control Regeneration and Hepatocarcinogenesis in a Murine Liver Injury Model.
Volume: 11
Issue: 5
Pages: 1387-1404
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26609054 | J:237555
First Author: Finnberg NK
Year: 2016
Journal: Cancer Res
Title: Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity.
Volume: 76
Issue: 3
Pages: 700-12
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24120666 | J:205983
First Author: Gupta GP
Year: 2013
Journal: Mol Cell
Title: The Mre11 complex suppresses oncogene-driven breast tumorigenesis and metastasis.
Volume: 52
Issue: 3
Pages: 353-65
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21625617 | J:172721
First Author: El Ghamrasni S
Year: 2011
Journal: PLoS Genet
Title: Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.
Volume: 7
Issue: 5
Pages: e1001385
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21156285 | J:167610
First Author: Squatrito M
Year: 2010
Journal: Cancer Cell
Title: Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas.
Volume: 18
Issue: 6
Pages: 619-29
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14744935 | J:88275
First Author: Qu L
Year: 2004
Journal: Genes Dev
Title: Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta.
Volume: 18
Issue: 3
Pages: 261-77
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15108799 | J:90177
First Author: Motoyama N
Year: 2004
Journal: Curr Opin Genet Dev
Title: DNA damage tumor suppressor genes and genomic instability.
Volume: 14
Issue: 1
Pages: 11-6
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17157788 | J:172986
First Author: Bruno T
Year: 2006
Journal: Cancer Cell
Title: Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.
Volume: 10
Issue: 6
Pages: 473-86
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24911145 | J:213794
First Author: Zhu Y
Year: 2014
Journal: J Clin Invest
Title: Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging.
Volume: 124
Issue: 7
Pages: 3263-73
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33854442 | J:306240
 
First Author: Yamaguchi H
Year: 2021
Journal: Front Physiol
Title: Alteration of DNA Damage Response Causes Cleft Palate.
Volume: 12
Pages: 649492
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19716796 | J:154193
First Author: Cao L
Year: 2009
Journal: Mol Cell
Title: A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Volume: 35
Issue: 4
Pages: 534-41
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16675955 | J:108783
First Author: Cao L
Year: 2006
Journal: EMBO J
Title: ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.
Volume: 25
Issue: 10
Pages: 2167-77
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25768017 | J:224234
First Author: Pacheco S
Year: 2015
Journal: PLoS Genet
Title: The ATM signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes.
Volume: 11
Issue: 3
Pages: e1005017
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24482479 | J:207474
First Author: Bolcun-Filas E
Year: 2014
Journal: Science
Title: Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway.
Volume: 343
Issue: 6170
Pages: 533-6
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30679733 | J:275921
First Author: El Hajjar J
Year: 2019
Journal: Sci Rep
Title: Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice.
Volume: 9
Issue: 1
Pages: 594
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20086180 | J:156862
First Author: Rotolo JA
Year: 2010
Journal: Cancer Res
Title: Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes.
Volume: 70
Issue: 3
Pages: 957-67
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16357220 | J:103922
First Author: Morales M
Year: 2005
Journal: Genes Dev
Title: The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.
Volume: 19
Issue: 24
Pages: 3043-54
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26388201 | J:227662
First Author: Luo Y
Year: 2015
Journal: Genesis
Title: MCM9 deficiency delays primordial germ cell proliferation independent of the ATM pathway.
Volume: 53
Issue: 11
Pages: 678-84
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23975433 | J:228556
First Author: Wallace MD
Year: 2014
Journal: Oncogene
Title: Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress.
Volume: 33
Issue: 28
Pages: 3688-95
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26427872 | J:233087
First Author: Dong D
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Maternal diabetes triggers DNA damage and DNA damage response in neurulation stage embryos through oxidative stress.
Volume: 467
Issue: 2
Pages: 407-12
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10710310 | J:60946
First Author: Hirao A
Year: 2000
Journal: Science
Title: DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Volume: 287
Issue: 5459
Pages: 1824-7
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37545879 | J:338956
 
First Author: de Campos VS
Year: 2023
Journal: Front Cell Neurosci
Title: Maternal Toxoplasma gondii infection affects proliferation, differentiation and cell cycle regulation of retinal neural progenitor cells in mouse embryo.
Volume: 17
Pages: 1211446
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22670056 | J:185501
First Author: Foster SS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression.
Volume: 109
Issue: 25
Pages: 9953-8
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18614044 | J:138550
First Author: Stracker TH
Year: 2008
Journal: Mol Cell
Title: Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage.
Volume: 31
Issue: 1
Pages: 21-32
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19966290 | J:156500
First Author: Jankovic M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Role of the translocation partner in protection against AID-dependent chromosomal translocations.
Volume: 107
Issue: 1
Pages: 187-92
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34193422 | J:314615
 
First Author: Xu C
Year: 2021
Journal: Sci Adv
Title: Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin.
Volume: 7
Issue: 27
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23683352 | J:261356
First Author: Zhou ZW
Year: 2013
Journal: DNA Repair (Amst)
Title: DNA damage response in microcephaly development of MCPH1 mouse model.
Volume: 12
Issue: 8
Pages: 645-55
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33586242 | J:306148
First Author: Chen Y
Year: 2021
Journal: Cell Prolif
Title: Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
Volume: 54
Issue: 3
Pages: e12972
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31949138 | J:283781
First Author: Tharp ME
Year: 2020
Journal: Nat Commun
Title: Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity.
Volume: 11
Issue: 1
Pages: 330
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24550317 | J:206795
First Author: Khoury-Haddad H
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair.
Volume: 111
Issue: 7
Pages: E728-37
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22555459 | J:204789
First Author: Demidov ON
Year: 2012
Journal: Cell Death Differ
Title: Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis.
Volume: 19
Issue: 11
Pages: 1761-8
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28276606 | J:252381
First Author: Kokavec J
Year: 2017
Journal: Stem Cells
Title: The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells.
Volume: 35
Issue: 6
Pages: 1614-1623
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24899707 | J:211631
First Author: Lee Y
Year: 2014
Journal: J Neurosci
Title: Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss.
Volume: 34
Issue: 23
Pages: 7836-44
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28123024 | J:239152
First Author: Enriquez-Rios V
Year: 2017
Journal: J Neurosci
Title: DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
Volume: 37
Issue: 4
Pages: 893-905
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24009519 | J:223048
First Author: Pirouz M
Year: 2013
Journal: PLoS Genet
Title: A critical function of Mad2l2 in primordial germ cell development of mice.
Volume: 9
Issue: 8
Pages: e1003712
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22360967 | J:184928
First Author: Miles DC
Year: 2012
Journal: Dev Biol
Title: The proto-oncogene Ret is required for male foetal germ cell survival.
Volume: 365
Issue: 1
Pages: 101-9
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29718910 | J:263685
First Author: Kitami K
Year: 2018
Journal: PLoS Genet
Title: BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development.
Volume: 14
Issue: 5
Pages: e1007340
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27358050 | J:240786
 
First Author: Lee DH
Year: 2016
Journal: Nat Commun
Title: LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
Volume: 7
Pages: 11961
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22522401 | J:191367
First Author: Lee Y
Year: 2012
Journal: Nat Neurosci
Title: Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors.
Volume: 15
Issue: 6
Pages: 819-26
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26023099 | J:224084
First Author: Elliott EN
Year: 2015
Journal: Development
Title: Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium.
Volume: 142
Issue: 12
Pages: 2163-72
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22266795 | J:181920
First Author: Lee Y
Year: 2012
Journal: EMBO J
Title: ATR maintains select progenitors during nervous system development.
Volume: 31
Issue: 5
Pages: 1177-89
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Publication
26158450 | J:224364
 
First Author: Marjanović M
Year: 2015
Journal: Nat Commun
Title: CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination.
Volume: 6
Pages: 7676
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22212482 | J:316150
First Author: Li R
Year: 2012
Journal: Cell Res
Title: A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons.
Volume: 22
Issue: 5
Pages: 859-72
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25043184 | J:266021
First Author: Foronda M
Year: 2014
Journal: Cell Rep
Title: Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation.
Volume: 8
Issue: 2
Pages: 487-500
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Publication
33798452 | J:314103
First Author: Ulmke PA
Year: 2021
Journal: Stem Cell Reports
Title: Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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