|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 273 for Chek2

<< First    < Previous  |  Next >    Last >>
0.092s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_15
Specimen Label: euxassay_012795_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_16
Specimen Label: euxassay_012795_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_17
Specimen Label: euxassay_012795_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_18
Specimen Label: euxassay_012795_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_19
Specimen Label: euxassay_012795_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_20
Specimen Label: euxassay_012795_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_02
Specimen Label: euxassay_012795_02
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_03
Specimen Label: euxassay_012795_03
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_04
Specimen Label: euxassay_012795_04
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_05
Specimen Label: euxassay_012795_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_06
Specimen Label: euxassay_012795_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_07
Specimen Label: euxassay_012795_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_08
Specimen Label: euxassay_012795_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_09
Specimen Label: euxassay_012795_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_10
Specimen Label: euxassay_012795_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_11
Specimen Label: euxassay_012795_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_12
Specimen Label: euxassay_012795_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_13
Specimen Label: euxassay_012795_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_14
Specimen Label: euxassay_012795_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_15
Specimen Label: euxassay_012795_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_16
Specimen Label: euxassay_012795_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_17
Specimen Label: euxassay_012795_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_18
Specimen Label: euxassay_012795_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_19
Specimen Label: euxassay_012795_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_20
Specimen Label: euxassay_012795_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506724
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5539702
Age: embryonic day 15.5
Image: GUDMAP:6063
Specimen Label: GUDMAP:6063
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506724
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539702
Age: embryonic day 15.5
Image: GUDMAP:6063
Specimen Label: GUDMAP:6063
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_09
Specimen Label: euxassay_012795_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_10
Specimen Label: euxassay_012795_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_11
Specimen Label: euxassay_012795_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_12
Specimen Label: euxassay_012795_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_13
Specimen Label: euxassay_012795_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_14
Specimen Label: euxassay_012795_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_15
Specimen Label: euxassay_012795_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823842
Age: embryonic day 14.5
Image: euxassay_012795_16
Specimen Label: euxassay_012795_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506724
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539702
Age: embryonic day 15.5
Image: GUDMAP:6063
Specimen Label: GUDMAP:6063
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4417369
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540495
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506724
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5539702
Age: embryonic day 15.5
Image: GUDMAP:6063
Specimen Label: GUDMAP:6063
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506724
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5539702
Age: embryonic day 15.5
Image: GUDMAP:6063
Specimen Label: GUDMAP:6063
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506724
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5539702
Age: embryonic day 15.5
Image: GUDMAP:6063
Specimen Label: GUDMAP:6063
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691540
Age: postnatal adult
Image: JAX_1803089
Specimen Label: JAX_1803089
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506724
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539702
Age: embryonic day 15.5
Image: GUDMAP:6063
Specimen Label: GUDMAP:6063
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691540
Age: postnatal adult
Image: JAX_1803090
Specimen Label: JAX_1803090
Detected: true
Specimen Num: 2
•
•
•
•
•
Publication
27767095 | J:262094
First Author: Adhikari D
Year: 2016
Journal: Cell Res
Title: Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan.
Volume: 26
Issue: 11
Pages: 1212-1225
•
•
•
•
•
Publication
29805302 | J:288589
First Author: Zhang Y
Year: 2018
Journal: Int J Biol Sci
Title: DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide.
Volume: 14
Issue: 5
Pages: 508-517
•
•
•
•
•
Publication
24920220 | J:217323
First Author: García-Beccaria M
Year: 2014
Journal: Aging Cell
Title: In vivo role of checkpoint kinase 2 in signaling telomere dysfunction.
Volume: 13
Issue: 5
Pages: 810-6
•
•
•
•
•
Publication
23449389 | J:228256
First Author: Bohgaki M
Year: 2013
Journal: Cell Death Differ
Title: The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover.
Volume: 20
Issue: 6
Pages: 812-22
•
•
•
•
•
Publication
29859927 | J:270504
First Author: Tanoue Y
Year: 2018
Journal: J Invest Dermatol
Title: Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure.
Volume: 138
Issue: 12
Pages: 2550-2557
•
•
•
•
•
Publication
33097538 | J:299008
 
First Author: Powers NR
Year: 2020
Journal: Sci Adv
Title: Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard.
Volume: 6
Issue: 43
•
•
•
•
•
Publication
31209362 | J:290678
First Author: Zhang W
Year: 2020
Journal: Cell Death Differ
Title: SIRT1 modulates cell cycle progression by regulating CHK2 acetylation-phosphorylation.
Volume: 27
Issue: 2
Pages: 482-496
•
•
•
•
•
Publication
33690219 | J:305920
 
First Author: Xiang J
Year: 2021
Journal: J Clin Invest
Title: Gluconeogenic enzyme PCK1 deficiency promotes CHK2 O-GlcNAcylation and hepatocellular carcinoma growth upon glucose deprivation.
Volume: 131
Issue: 8
•
•
•
•
•
Publication
34349265 | J:326210
First Author: Ruth KS
Year: 2021
Journal: Nature
Title: Genetic insights into biological mechanisms governing human ovarian ageing.
Volume: 596
Issue: 7872
Pages: 393-397
•
•
•
•
•
Publication
19404261 | J:148536
First Author: Liu J
Year: 2009
Journal: Nature
Title: Bmi1 regulates mitochondrial function and the DNA damage response pathway.
Volume: 459
Issue: 7245
Pages: 387-392
•
•
•
•
•
Publication
20834228 | J:165429
First Author: Niida H
Year: 2010
Journal: EMBO J
Title: Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo.
Volume: 29
Issue: 20
Pages: 3558-70
•
•
•
•
•
Publication
12356735 | J:88888
First Author: Takai H
Year: 2002
Journal: EMBO J
Title: Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription.
Volume: 21
Issue: 19
Pages: 5195-205
•
•
•
•
•
Publication
17360434 | J:120057
First Author: Zaugg K
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.
Volume: 104
Issue: 10
Pages: 3805-10
•
•
•
•
•
Publication
21791608 | J:175866
First Author: Ullah Z
Year: 2011
Journal: Mol Cell Biol
Title: Checkpoint kinase 1 prevents cell cycle exit linked to terminal cell differentiation.
Volume: 31
Issue: 19
Pages: 4129-43
•
•
•
•
•
Publication
21745814 | J:183033
First Author: Yu TX
Year: 2011
Journal: Nucleic Acids Res
Title: Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function.
Volume: 39
Issue: 19
Pages: 8472-87
•
•
•
•
•
Publication
15893606 | J:99333
First Author: Matsuki T
Year: 2005
Journal: Brain Res Mol Brain Res
Title: Gene expression profiling during the embryonic development of mouse brain using an oligonucleotide-based microarray system.
Volume: 136
Issue: 1-2
Pages: 231-54
•
•
•
•
•
Publication
22448250 | J:187030
First Author: Chen CH
Year: 2012
Journal: PLoS One
Title: Disruption of murine mp29/Syf2/Ntc31 gene results in embryonic lethality with aberrant checkpoint response.
Volume: 7
Issue: 3
Pages: e33538
•
•
•
•
•
Publication
22499945 | J:183932
First Author: Lee IH
Year: 2012
Journal: Science
Title: Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress.
Volume: 336
Issue: 6078
Pages: 225-8
•
•
•
•
•
Publication
12192050 | J:78491
First Author: Hirao A
Year: 2002
Journal: Mol Cell Biol
Title: Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.
Volume: 22
Issue: 18
Pages: 6521-32
•
•
•
•
•
Publication
28844861 | J:253200
First Author: Rinaldi VD
Year: 2017
Journal: Mol Cell
Title: The DNA Damage Checkpoint Eliminates Mouse Oocytes with Chromosome Synapsis Failure.
Volume: 67
Issue: 6
Pages: 1026-1036.e2
•
•
•
•
•
Publication
15131084 | J:90512
First Author: McPherson JP
Year: 2004
Journal: Genes Dev
Title: Collaboration of Brca1 and Chk2 in tumorigenesis.
Volume: 18
Issue: 10
Pages: 1144-53
•
•
•
•
•
Publication
12097646 | J:126186
First Author: Jack MT
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response.
Volume: 99
Issue: 15
Pages: 9825-9
•
•
•
•
•
Publication
18086870 | J:131583
First Author: Zheng L
Year: 2008
Journal: Blood
Title: TLR9 engagement on CD4 T lymphocytes represses gamma-radiation-induced apoptosis through activation of checkpoint kinase response elements.
Volume: 111
Issue: 5
Pages: 2704-13
•
•
•
•
•
Publication
33484913 | J:314024
First Author: Buitrago-Molina LE
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: p53-Independent Induction of p21 Fails to Control Regeneration and Hepatocarcinogenesis in a Murine Liver Injury Model.
Volume: 11
Issue: 5
Pages: 1387-1404
•
•
•
•
•
Publication
26609054 | J:237555
First Author: Finnberg NK
Year: 2016
Journal: Cancer Res
Title: Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity.
Volume: 76
Issue: 3
Pages: 700-12
•
•
•
•
•
Publication
24120666 | J:205983
First Author: Gupta GP
Year: 2013
Journal: Mol Cell
Title: The Mre11 complex suppresses oncogene-driven breast tumorigenesis and metastasis.
Volume: 52
Issue: 3
Pages: 353-65
•
•
•
•
•
Publication
30305635 | J:268570
First Author: Abreu CM
Year: 2018
Journal: Nat Commun
Title: Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination.
Volume: 9
Issue: 1
Pages: 3961
•
•
•
•
•
Publication
21625617 | J:172721
First Author: El Ghamrasni S
Year: 2011
Journal: PLoS Genet
Title: Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.
Volume: 7
Issue: 5
Pages: e1001385
•
•
•
•
•
Publication
21156285 | J:167610
First Author: Squatrito M
Year: 2010
Journal: Cancer Cell
Title: Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas.
Volume: 18
Issue: 6
Pages: 619-29
•
•
•
•
•
Publication
14744935 | J:88275
First Author: Qu L
Year: 2004
Journal: Genes Dev
Title: Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta.
Volume: 18
Issue: 3
Pages: 261-77
•
•
•
•
•
Publication
15108799 | J:90177
First Author: Motoyama N
Year: 2004
Journal: Curr Opin Genet Dev
Title: DNA damage tumor suppressor genes and genomic instability.
Volume: 14
Issue: 1
Pages: 11-6
•
•
•
•
•
Publication
17157788 | J:172986
First Author: Bruno T
Year: 2006
Journal: Cancer Cell
Title: Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.
Volume: 10
Issue: 6
Pages: 473-86
•
•
•
•
•
Publication
16675955 | J:108783
First Author: Cao L
Year: 2006
Journal: EMBO J
Title: ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.
Volume: 25
Issue: 10
Pages: 2167-77
•
•
•
•
•
Publication
19716796 | J:154193
First Author: Cao L
Year: 2009
Journal: Mol Cell
Title: A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Volume: 35
Issue: 4
Pages: 534-41
•
•
•
•
•
Publication
33854442 | J:306240
 
First Author: Yamaguchi H
Year: 2021
Journal: Front Physiol
Title: Alteration of DNA Damage Response Causes Cleft Palate.
Volume: 12
Pages: 649492
•
•
•
•
•
Publication
25768017 | J:224234
First Author: Pacheco S
Year: 2015
Journal: PLoS Genet
Title: The ATM signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes.
Volume: 11
Issue: 3
Pages: e1005017
•
•
•
•
•
Publication
24482479 | J:207474
First Author: Bolcun-Filas E
Year: 2014
Journal: Science
Title: Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway.
Volume: 343
Issue: 6170
Pages: 533-6
•
•
•
•
•
Publication
24911145 | J:213794
First Author: Zhu Y
Year: 2014
Journal: J Clin Invest
Title: Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging.
Volume: 124
Issue: 7
Pages: 3263-73
•
•
•
•
•
Publication
16357220 | J:103922
First Author: Morales M
Year: 2005
Journal: Genes Dev
Title: The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.
Volume: 19
Issue: 24
Pages: 3043-54
•
•
•
•
•
Publication
30679733 | J:275921
First Author: El Hajjar J
Year: 2019
Journal: Sci Rep
Title: Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice.
Volume: 9
Issue: 1
Pages: 594
•
•
•
•
•
Publication
23975433 | J:228556
First Author: Wallace MD
Year: 2014
Journal: Oncogene
Title: Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress.
Volume: 33
Issue: 28
Pages: 3688-95
•
•
•
•
•
Publication
26388201 | J:227662
First Author: Luo Y
Year: 2015
Journal: Genesis
Title: MCM9 deficiency delays primordial germ cell proliferation independent of the ATM pathway.
Volume: 53
Issue: 11
Pages: 678-84
•
•
•
•
•
Publication
20086180 | J:156862
First Author: Rotolo JA
Year: 2010
Journal: Cancer Res
Title: Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes.
Volume: 70
Issue: 3
Pages: 957-67
•
•
•
•
•
Publication
10710310 | J:60946
First Author: Hirao A
Year: 2000
Journal: Science
Title: DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Volume: 287
Issue: 5459
Pages: 1824-7
•
•
•
•
•
Publication
26427872 | J:233087
First Author: Dong D
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Maternal diabetes triggers DNA damage and DNA damage response in neurulation stage embryos through oxidative stress.
Volume: 467
Issue: 2
Pages: 407-12
•
•
•
•
•
Publication
37545879 | J:338956
 
First Author: de Campos VS
Year: 2023
Journal: Front Cell Neurosci
Title: Maternal Toxoplasma gondii infection affects proliferation, differentiation and cell cycle regulation of retinal neural progenitor cells in mouse embryo.
Volume: 17
Pages: 1211446
•
•
•
•
•
Publication
22670056 | J:185501
First Author: Foster SS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression.
Volume: 109
Issue: 25
Pages: 9953-8
•
•
•
•
•
Publication
18614044 | J:138550
First Author: Stracker TH
Year: 2008
Journal: Mol Cell
Title: Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage.
Volume: 31
Issue: 1
Pages: 21-32
•
•
•
•
•
Publication
19966290 | J:156500
First Author: Jankovic M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Role of the translocation partner in protection against AID-dependent chromosomal translocations.
Volume: 107
Issue: 1
Pages: 187-92
•
•
•
•
•
Publication
34193422 | J:314615
 
First Author: Xu C
Year: 2021
Journal: Sci Adv
Title: Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin.
Volume: 7
Issue: 27
•
•
•
•
•
Publication
23683352 | J:261356
First Author: Zhou ZW
Year: 2013
Journal: DNA Repair (Amst)
Title: DNA damage response in microcephaly development of MCPH1 mouse model.
Volume: 12
Issue: 8
Pages: 645-55
•
•
•
•
•
Publication
33586242 | J:306148
First Author: Chen Y
Year: 2021
Journal: Cell Prolif
Title: Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
Volume: 54
Issue: 3
Pages: e12972
•
•
•
•
•
Publication
31949138 | J:283781
First Author: Tharp ME
Year: 2020
Journal: Nat Commun
Title: Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity.
Volume: 11
Issue: 1
Pages: 330
•
•
•
•
•
Publication
24550317 | J:206795
First Author: Khoury-Haddad H
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair.
Volume: 111
Issue: 7
Pages: E728-37
•
•
•
•
•
Publication
22555459 | J:204789
First Author: Demidov ON
Year: 2012
Journal: Cell Death Differ
Title: Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis.
Volume: 19
Issue: 11
Pages: 1761-8
•
•
•
•
•
Publication
28276606 | J:252381
First Author: Kokavec J
Year: 2017
Journal: Stem Cells
Title: The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells.
Volume: 35
Issue: 6
Pages: 1614-1623
•
•
•
•
•
Publication
24899707 | J:211631
First Author: Lee Y
Year: 2014
Journal: J Neurosci
Title: Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss.
Volume: 34
Issue: 23
Pages: 7836-44
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom