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Search results 101 to 146 out of 146 for Ecd

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Type Details Score
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: angiotensin converting enzyme 2; endonuclease-mediated mutation 2, Janet Rossant
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence, Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
MP Term
MP Term
MP Term
MP Term
DO Term
MP Term
Publication
First Author: Mavrici D
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC.
Volume: 111
Issue: 22
Pages: 8037-42
Protein Domain
Type: Domain
Description: This is the extracellular domain (ECD) found in FtsX, a homologue of the transmembrane PG-hydrolase regulator. The FtsX extracellular domain binds the PG peptidase Rv2190c/RipC N-terminal segment, causing a conformational change that activates the enzyme ileading to PG hydrolysis in Mycobacterium tuberculosis. Structural analysis of FtsX ECD reveals fold containing two lobes connected by a flexible hinge. Mutations in the hydrophobic cleft between the lobes showed reduction in RipC binding in vitro and inhibition of FtsX function in Mycobacterium smegmatis [].
Allele  
Name: Mutant line 251; Bench to Bassinet Program (B2B/CVDC), mutation 251 Cecilia Lo
Allele Type: Chemically induced (ENU)
Strain
Attribute String: coisogenic, chemically induced mutation, mutant strain
Strain
Attribute String: coisogenic, chemically induced mutation, mutant strain
Allele  
Name: centrosomal protein 290; Bench to Bassinet Program (B2B/CVDC), mutation 1454 Cecilia Lo
Allele Type: Chemically induced (ENU)
Genotype
Symbol: b2b251Clo/b2b251Clo
Background: C57BL/6J-b2b251Clo
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Previtali SC
Year: 2000
Journal: J Cell Biol
Title: Epitope-tagged P(0) glycoprotein causes Charcot-Marie-Tooth-like neuropathy in transgenic mice.
Volume: 151
Issue: 5
Pages: 1035-46
Publication
First Author: Yang C
Year: 2023
Journal: Nat Commun
Title: A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury.
Volume: 14
Issue: 1
Pages: 4261
Publication
First Author: Basak S
Year: 2018
Journal: Nature
Title: Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3A receptor.
Volume: 563
Issue: 7730
Pages: 270-274
Publication
First Author: Greenwald J
Year: 2003
Journal: Mol Cell
Title: The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly.
Volume: 11
Issue: 3
Pages: 605-17
Strain
Attribute String: mutant strain, chemically induced mutation, coisogenic
Strain
Attribute String: coisogenic, chemically induced mutation, mutant strain
Genotype
Symbol: Cep290/Cep290
Background: C57BL/6J-Cep290
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Castonguay R
Year: 2011
Journal: J Biol Chem
Title: Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.
Volume: 286
Issue: 34
Pages: 30034-46
Publication
First Author: Shikano S
Year: 2001
Journal: J Biol Chem
Title: Molecular cloning of a dendritic cell-associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulfate proteoglycans.
Volume: 276
Issue: 11
Pages: 8125-34
Publication
First Author: Yoshida T
Year: 2011
Journal: J Neurosci
Title: IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase δ.
Volume: 31
Issue: 38
Pages: 13485-99
Publication
First Author: Brown LE
Year: 2016
Journal: J Biol Chem
Title: γ-Aminobutyric Acid Type A (GABAA) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains.
Volume: 291
Issue: 27
Pages: 13926-42
Publication
First Author: Li W
Year: 2015
Journal: J Biol Chem
Title: Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1.
Volume: 290
Issue: 31
Pages: 18904-13
Publication
First Author: Rovero S
Year: 2001
Journal: Gene Ther
Title: Insertion of the DNA for the 163-171 peptide of IL1beta enables a DNA vaccine encoding p185(neu) to inhibit mammary carcinogenesis in Her-2/neu transgenic BALB/c mice.
Volume: 8
Issue: 6
Pages: 447-52
Publication
First Author: Stowie A
Year: 2019
Journal: PLoS One
Title: A reductionist, in vitro model of environmental circadian disruption demonstrates SCN-independent and tissue-specific dysregulation of inflammatory responses.
Volume: 14
Issue: 5
Pages: e0217368
Publication
First Author: Rajagopal SK
Year: 2007
Journal: J Mol Cell Cardiol
Title: Spectrum of heart disease associated with murine and human GATA4 mutation.
Volume: 43
Issue: 6
Pages: 677-85
Publication
First Author: Pirotte D
Year: 2010
Journal: Mol Cell Neurosci
Title: Neuregulin-1 modulates the differentiation of neural stem cells in vitro through an interaction with the Swi/Snf complex.
Volume: 43
Issue: 1
Pages: 72-80
Publication
First Author: Flynn LA
Year: 2010
Journal: J Mol Biol
Title: Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2.
Volume: 395
Issue: 3
Pages: 533-43
Publication
First Author: Zhu X
Year: 2000
Journal: J Biol Chem
Title: Identification of key functional amino acids of the mouse fertilin beta (ADAM2) disintegrin loop for cell-cell adhesion during fertilization.
Volume: 275
Issue: 11
Pages: 7677-83
Publication
First Author: Gosu V
Year: 2019
Journal: Sci Rep
Title: Insights into the dynamic nature of the dsRNA-bound TLR3 complex.
Volume: 9
Issue: 1
Pages: 3652
Publication
First Author: Mohapatra BC
Year: 2022
Journal: Mol Cancer Res
Title: Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism.
Volume: 20
Issue: 9
Pages: 1391-1404
Publication  
First Author: Yuki K
Year: 2024
Journal: Development
Title: GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism.
Volume: 151
Issue: 11
Publication
First Author: Jing H
Year: 2021
Journal: Cell Biosci
Title: Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway.
Volume: 11
Issue: 1
Pages: 105
Publication
First Author: Scapin G
Year: 2018
Journal: Nature
Title: Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Volume: 556
Issue: 7699
Pages: 122-125
Publication
First Author: Labrecque J
Year: 1999
Journal: J Biol Chem
Title: A disulfide-bridged mutant of natriuretic peptide receptor-A displays constitutive activity. Role of receptor dimerization in signal transduction.
Volume: 274
Issue: 14
Pages: 9752-9
Publication
First Author: Gilchrist RB
Year: 2006
Journal: J Cell Sci
Title: Molecular basis of oocyte-paracrine signalling that promotes granulosa cell proliferation.
Volume: 119
Issue: Pt 18
Pages: 3811-21
Publication      
First Author: The Centre for Phenogenomics
Year: 2022
Journal: MGI Direct Data Submission
Title: Direct Data Submission for The Centre for Phenogenomics Alleles.
Publication  
First Author: San Agustin JT
Year: 2016
Journal: Nat Commun
Title: Genetic link between renal birth defects and congenital heart disease.
Volume: 7
Pages: 11103
Publication
First Author: Li Y
Year: 2015
Journal: Nature
Title: Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Volume: 521
Issue: 7553
Pages: 520-4
Publication      
First Author: Lo C
Year: 2011
Journal: MGI Direct Data Submission (B2B/CvDC)
Title: Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC)