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Search results 701 to 800 out of 922 for Epas1

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Type Details Score
Publication
25023703 | J:221253
First Author: Pritchett TL
Year: 2015
Journal: Oncogene
Title: Conditional inactivation of the mouse von Hippel-Lindau tumor suppressor gene results in wide-spread hyperplastic, inflammatory and fibrotic lesions in the kidney.
Volume: 34
Issue: 20
Pages: 2631-9
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Publication
20628150 | J:165868
First Author: Kapitsinou PP
Year: 2010
Journal: Blood
Title: Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia.
Volume: 116
Issue: 16
Pages: 3039-48
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Publication
27798602 | J:243079
First Author: Tyrakis PA
Year: 2016
Journal: Nature
Title: S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate.
Volume: 540
Issue: 7632
Pages: 236-241
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Publication
31695081 | J:287297
First Author: Samardzija M
Year: 2019
Journal: Sci Rep
Title: Hif1a and Hif2a can be safely inactivated in cone photoreceptors.
Volume: 9
Issue: 1
Pages: 16121
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Publication
19252526 | J:157369
First Author: Lee CM
Year: 2009
Journal: Oncogene
Title: VHL Type 2B gene mutation moderates HIF dosage in vitro and in vivo.
Volume: 28
Issue: 14
Pages: 1694-705
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Publication
20881124 | J:164878
First Author: Chen G
Year: 2010
Journal: J Neurosci
Title: CREB binding protein is required for both short-term and long-term memory formation.
Volume: 30
Issue: 39
Pages: 13066-77
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Publication
21814490 | J:175600
First Author: Zhang H
Year: 2011
Journal: PLoS Biol
Title: Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation.
Volume: 9
Issue: 7
Pages: e1001112
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Publication
24999590 | J:217942
First Author: Wong WJ
Year: 2015
Journal: J Invest Dermatol
Title: Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function.
Volume: 135
Issue: 2
Pages: 454-461
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Publication
25855602 | J:222624
First Author: Krock BL
Year: 2015
Journal: Blood
Title: The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability.
Volume: 125
Issue: 21
Pages: 3263-72
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Publication
29483579 | J:336384
First Author: Koeppen M
Year: 2018
Journal: Nat Commun
Title: Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury.
Volume: 9
Issue: 1
Pages: 816
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Publication
20197624 | J:158732
First Author: Hickey MM
Year: 2010
Journal: J Clin Invest
Title: The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice.
Volume: 120
Issue: 3
Pages: 827-39
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Publication
23264599 | J:194598
First Author: Franke K
Year: 2013
Journal: Blood
Title: HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Volume: 121
Issue: 8
Pages: 1436-45
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Publication
26642852 | J:229015
First Author: Vukovic M
Year: 2015
Journal: J Exp Med
Title: Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.
Volume: 212
Issue: 13
Pages: 2223-34
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Publication
26976644 | J:236191
First Author: Kapitsinou PP
Year: 2016
Journal: Mol Cell Biol
Title: The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice.
Volume: 36
Issue: 10
Pages: 1584-94
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Publication
24789906 | J:212930
First Author: Kapitsinou PP
Year: 2014
Journal: J Clin Invest
Title: Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury.
Volume: 124
Issue: 6
Pages: 2396-409
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Publication
30586708 | J:280004
First Author: Jiang X
Year: 2019
Journal: Circulation
Title: Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature.
Volume: 139
Issue: 4
Pages: 502-517
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Publication
35672324 | J:327519
First Author: Han JS
Year: 2022
Journal: Nat Commun
Title: Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes.
Volume: 13
Issue: 1
Pages: 3268
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Publication
38019933 | J:352513
First Author: Guo W
Year: 2023
Journal: Sci Transl Med
Title: Radiation-induced bone loss in mice is ameliorated by inhibition of HIF-2α in skeletal progenitor cells.
Volume: 15
Issue: 724
Pages: eabo5217
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Publication
27432976 | J:234394
First Author: Cowburn AS
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: HIF2α-arginase axis is essential for the development of pulmonary hypertension.
Volume: 113
Issue: 31
Pages: 8801-6
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Publication
22081627 | J:178824
First Author: Riddle RC
Year: 2011
Journal: J Biol Chem
Title: Hypoxia-inducible factor-1α protein negatively regulates load-induced bone formation.
Volume: 286
Issue: 52
Pages: 44449-56
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Publication
22684009 | J:186999
First Author: Pourvali K
Year: 2012
Journal: FEBS Lett
Title: Basal expression of copper transporter 1 in intestinal epithelial cells is regulated by hypoxia-inducible factor 2α.
Volume: 586
Issue: 16
Pages: 2423-7
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Publication
29049022 | J:250300
   
First Author: Cowburn AS
Year: 2017
Journal: Elife
Title: Cardiovascular adaptation to hypoxia and the role of peripheral resistance.
Volume: 6
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38455514 | J:360591
 
First Author: Ali SR
Year: 2024
Journal: J Cardiovasc Aging
Title: Hypoxia-induced stabilization of HIF2A promotes cardiomyocyte proliferation by attenuating DNA damage.
Volume: 4
Issue: 1
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27001147 | J:240855
 
First Author: Li L
Year: 2016
Journal: Neurobiol Dis
Title: Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner.
Volume: 91
Pages: 221-35
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25377876 | J:249475
First Author: Michailidou Z
Year: 2015
Journal: Diabetes
Title: Adipocyte pseudohypoxia suppresses lipolysis and facilitates benign adipose tissue expansion.
Volume: 64
Issue: 3
Pages: 733-45
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23749643 | J:199471
First Author: Criscimanna A
Year: 2013
Journal: Cancer Res
Title: PanIN-specific regulation of Wnt signaling by HIF2α during early pancreatic tumorigenesis.
Volume: 73
Issue: 15
Pages: 4781-90
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20660313 | J:163616
First Author: Mazumdar J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: HIF-2alpha deletion promotes Kras-driven lung tumor development.
Volume: 107
Issue: 32
Pages: 14182-7
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Publication
29190746 | J:252629
First Author: Scott CH
Year: 2017
Journal: PLoS One
Title: Hepatic Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) regulates metabolism in mice.
Volume: 12
Issue: 11
Pages: e0186543
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33357457 | J:303721
First Author: Chen Y
Year: 2021
Journal: Cell Metab
Title: Aging Reprograms the Hematopoietic-Vascular Niche to Impede Regeneration and Promote Fibrosis.
Volume: 33
Issue: 2
Pages: 395-410.e4
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21106753 | J:167144
First Author: Rasbach KA
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types.
Volume: 107
Issue: 50
Pages: 21866-71
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17553906 | J:122753
First Author: Tozer S
Year: 2007
Journal: Development
Title: Involvement of vessels and PDGFB in muscle splitting during chick limb development.
Volume: 134
Issue: 14
Pages: 2579-91
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24760996 | J:240918
First Author: Tsui AK
Year: 2014
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Differential HIF and NOS responses to acute anemia: defining organ-specific hemoglobin thresholds for tissue hypoxia.
Volume: 307
Issue: 1
Pages: R13-25
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Publication
29036334 | J:254388
First Author: Wang J
Year: 2017
Journal: Nucleic Acids Res
Title: Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity.
Volume: 45
Issue: 22
Pages: 12700-12714
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Publication
39609127 | J:360990
First Author: Zou X
Year: 2024
Journal: Immunity
Title: Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism.
Volume: 57
Issue: 12
Pages: 2808-2826.e8
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Publication
24030251 | J:211224
First Author: Bondeva T
Year: 2013
Journal: Mol Endocrinol
Title: Advanced glycated end-products affect HIF-transcriptional activity in renal cells.
Volume: 27
Issue: 11
Pages: 1918-33
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Publication
12464608 | J:82142
First Author: Elvert G
Year: 2003
Journal: J Biol Chem
Title: Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1).
Volume: 278
Issue: 9
Pages: 7520-30
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10813585 | J:63357
First Author: Bhatt AJ
Year: 2000
Journal: Pediatr Res
Title: Expression of vascular endothelial growth factor and Flk-1 in developing and glucocorticoid-treated mouse lung.
Volume: 47
Issue: 5
Pages: 606-13
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15117738 | J:101671
First Author: Wagner KF
Year: 2004
Journal: Am J Respir Cell Mol Biol
Title: Hypoxia-induced mitogenic factor has antiapoptotic action and is upregulated in the developing lung: coexpression with hypoxia-inducible factor-2alpha.
Volume: 31
Issue: 3
Pages: 276-82
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Publication
22033266 | J:196040
First Author: Raghavan A
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Hypoxia-induced pulmonary arterial smooth muscle cell proliferation is controlled by forkhead box M1.
Volume: 46
Issue: 4
Pages: 431-6
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Publication
35912776 | J:331512
First Author: Kimura S
Year: 2022
Journal: J Dent Res
Title: HIF-2α Inhibits Ameloblast Differentiation via Hey2 in Tooth Development.
Volume: 101
Issue: 13
Pages: 1637-1644
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Publication
9113979 | J:41526
First Author: Ema M
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development.
Volume: 94
Issue: 9
Pages: 4273-8
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18332118 | J:136034
First Author: Bishop T
Year: 2008
Journal: Mol Cell Biol
Title: Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice.
Volume: 28
Issue: 10
Pages: 3386-400
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9704006 | J:49044
First Author: Takahata S
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock.
Volume: 248
Issue: 3
Pages: 789-94
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18176562 | J:132630
First Author: Aragonés J
Year: 2008
Journal: Nat Genet
Title: Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.
Volume: 40
Issue: 2
Pages: 170-80
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22014577 | J:177485
First Author: Adam J
Year: 2011
Journal: Cancer Cell
Title: Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Volume: 20
Issue: 4
Pages: 524-37
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22419665 | J:185744
First Author: Xue X
Year: 2012
Journal: Cancer Res
Title: Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis.
Volume: 72
Issue: 9
Pages: 2285-93
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Publication
27956697 | J:244844
 
First Author: Triner D
Year: 2017
Journal: Mol Cell Biol
Title: Epithelial Hypoxia-Inducible Factor 2α Facilitates the Progression of Colon Tumors through Recruiting Neutrophils.
Volume: 37
Issue: 5
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Publication
25414188 | J:230295
First Author: Rattner A
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: The role of the hypoxia response in shaping retinal vascular development in the absence of Norrin/Frizzled4 signaling.
Volume: 55
Issue: 12
Pages: 8614-25
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Publication
35192456 | J:321651
   
First Author: Ajouaou Y
Year: 2022
Journal: Elife
Title: The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells.
Volume: 11
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22490864 | J:188688
First Author: Kobayashi H
Year: 2012
Journal: J Immunol
Title: Myeloid cell-derived hypoxia-inducible factor attenuates inflammation in unilateral ureteral obstruction-induced kidney injury.
Volume: 188
Issue: 10
Pages: 5106-15
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24121508 | J:202737
First Author: Arsenault PR
Year: 2013
Journal: J Biol Chem
Title: A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficiency mechanism.
Volume: 288
Issue: 47
Pages: 33571-84
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16287860 | J:119854
First Author: Cowden Dahl KD
Year: 2005
Journal: Mol Cell Biol
Title: Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation.
Volume: 25
Issue: 23
Pages: 10479-91
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29078383 | J:257262
First Author: Xue X
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.
Volume: 114
Issue: 45
Pages: E9608-E9617
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28848049 | J:246046
First Author: Ma X
Year: 2017
Journal: J Biol Chem
Title: Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity.
Volume: 292
Issue: 41
Pages: 17046-17056
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25103499 | J:216067
First Author: Joshi S
Year: 2014
Journal: Mol Cancer Res
Title: A macrophage-dominant PI3K isoform controls hypoxia-induced HIF1α and HIF2α stability and tumor growth, angiogenesis, and metastasis.
Volume: 12
Issue: 10
Pages: 1520-31
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24599965 | J:216543
First Author: Imamura Y
Year: 2014
Journal: FASEB J
Title: HIF-2α/ARNT complex regulates hair development via induction of p21(Waf1/Cip1) and p27(Kip1).
Volume: 28
Issue: 6
Pages: 2517-24
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22084310 | J:178823
First Author: Kurihara T
Year: 2011
Journal: J Cell Biol
Title: Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye.
Volume: 195
Issue: 4
Pages: 689-701
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20544853 | J:168049
First Author: Weidemann A
Year: 2010
Journal: Glia
Title: Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina.
Volume: 58
Issue: 10
Pages: 1177-85
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19809162 | J:154613
First Author: Weidemann A
Year: 2009
Journal: J Clin Invest
Title: The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.
Volume: 119
Issue: 11
Pages: 3373-83
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26978795 | J:269718
   
First Author: Kurihara T
Year: 2016
Journal: Elife
Title: Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.
Volume: 5
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32332719 | J:294863
First Author: Zhang S
Year: 2020
Journal: Nat Commun
Title: Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways.
Volume: 11
Issue: 1
Pages: 2027
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22556263 | J:189318
First Author: Kim JW
Year: 2012
Journal: Cancer Res
Title: Loss of fibroblast HIF-1α accelerates tumorigenesis.
Volume: 72
Issue: 13
Pages: 3187-95
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32807776 | J:303341
First Author: Hoefflin R
Year: 2020
Journal: Nat Commun
Title: HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.
Volume: 11
Issue: 1
Pages: 4111
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31980651 | J:283888
First Author: Lee P
Year: 2020
Journal: Nat Commun
Title: Targeting glutamine metabolism slows soft tissue sarcoma growth.
Volume: 11
Issue: 1
Pages: 498
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26759234 | J:231634
First Author: Schönenberger D
Year: 2016
Journal: Cancer Res
Title: Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α.
Volume: 76
Issue: 7
Pages: 2025-36
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34699114 | J:317573
First Author: Vanderhaeghen T
Year: 2022
Journal: EMBO Rep
Title: Reprogramming of glucocorticoid receptor function by hypoxia.
Volume: 23
Issue: 1
Pages: e53083
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28555642 | J:251682
 
First Author: Kumar R
Year: 2017
Journal: Nat Commun
Title: TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.
Volume: 8
Pages: 15494
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27189088 | J:239927
 
First Author: Semba H
Year: 2016
Journal: Nat Commun
Title: HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.
Volume: 7
Pages: 11635
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21765015 | J:179156
First Author: Roda JM
Year: 2011
Journal: J Immunol
Title: Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis.
Volume: 187
Issue: 4
Pages: 1970-6
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36247475 | J:335313
 
First Author: Heck-Swain KL
Year: 2022
Journal: Front Cardiovasc Med
Title: Myeloid hypoxia-inducible factor HIF1A provides cardio-protection during ischemia and reperfusion via induction of netrin-1.
Volume: 9
Pages: 970415
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32673288 | J:302486
First Author: Jiang X
Year: 2020
Journal: J Clin Invest
Title: Decreased lymphatic HIF-2α accentuates lymphatic remodeling in lymphedema.
Volume: 130
Issue: 10
Pages: 5562-5575
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26503986 | J:252576
First Author: Labrousse-Arias D
Year: 2016
Journal: Cardiovasc Res
Title: HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction.
Volume: 109
Issue: 1
Pages: 115-30
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18439915 | J:136664
First Author: Shah YM
Year: 2008
Journal: Gastroenterology
Title: Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.
Volume: 134
Issue: 7
Pages: 2036-48, 2048.e1-3
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17404621 | J:121253
First Author: Rankin EB
Year: 2007
Journal: J Clin Invest
Title: Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo.
Volume: 117
Issue: 4
Pages: 1068-77
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26927670 | J:234569
First Author: Farsijani NM
Year: 2016
Journal: J Clin Invest
Title: Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin.
Volume: 126
Issue: 4
Pages: 1425-37
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26853750 | J:233030
First Author: Ramakrishnan SK
Year: 2016
Journal: Cell Metab
Title: HIF2α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.
Volume: 23
Issue: 3
Pages: 505-16
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24421394 | J:213532
First Author: Ramakrishnan SK
Year: 2014
Journal: Mol Cell Biol
Title: Loss of von Hippel-Lindau protein (VHL) increases systemic cholesterol levels through targeting hypoxia-inducible factor 2α and regulation of bile acid homeostasis.
Volume: 34
Issue: 7
Pages: 1208-20
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27501247 | J:236614
First Author: Cho SH
Year: 2016
Journal: Nature
Title: Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.
Volume: 537
Issue: 7619
Pages: 234-238
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25915585 | J:222971
First Author: Usui Y
Year: 2015
Journal: J Clin Invest
Title: Neurovascular crosstalk between interneurons and capillaries is required for vision.
Volume: 125
Issue: 6
Pages: 2335-46
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21447692 | J:181428
First Author: Lange C
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Normoxic activation of hypoxia-inducible factors in photoreceptors provides transient protection against light-induced retinal degeneration.
Volume: 52
Issue: 8
Pages: 5872-80
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Publication
18285456 | J:136012
First Author: Lei L
Year: 2008
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau protein.
Volume: 28
Issue: 11
Pages: 3790-803
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Publication
23114598 | J:193997
First Author: Liu Q
Year: 2012
Journal: J Clin Invest
Title: Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis.
Volume: 122
Issue: 12
Pages: 4635-44
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Publication
24891620 | J:224278
First Author: Xie L
Year: 2014
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor/MAZ-dependent induction of caveolin-1 regulates colon permeability through suppression of occludin, leading to hypoxia-induced inflammation.
Volume: 34
Issue: 16
Pages: 3013-23
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Publication
22464323 | J:186085
First Author: Rankin EB
Year: 2012
Journal: Cell
Title: The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.
Volume: 149
Issue: 1
Pages: 63-74
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Publication
22869521 | J:189135
First Author: Anderson ER
Year: 2012
Journal: Mol Cell Biol
Title: The hypoxia-inducible factor-C/EBPα axis controls ethanol-mediated hepcidin repression.
Volume: 32
Issue: 19
Pages: 4068-77
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23103253 | J:194004
First Author: Elorza A
Year: 2012
Journal: Mol Cell
Title: HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5.
Volume: 48
Issue: 5
Pages: 681-91
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Publication
22930750 | J:214713
First Author: Aro E
Year: 2012
Journal: J Biol Chem
Title: Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.
Volume: 287
Issue: 44
Pages: 37134-44
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Publication
35313689 | J:328675
First Author: Harada Y
Year: 2022
Journal: iScience
Title: Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes.
Volume: 25
Issue: 4
Pages: 104021
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Publication
33208471 | J:299965
First Author: Zhang S
Year: 2021
Journal: J Neurosci
Title: HIFα Regulates Developmental Myelination Independent of Autocrine Wnt Signaling.
Volume: 41
Issue: 2
Pages: 251-268
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Publication
25440060 | J:218787
First Author: Walter KM
Year: 2014
Journal: Cell Metab
Title: Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy.
Volume: 20
Issue: 5
Pages: 882-97
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Publication
21419768 | J:189504
First Author: Taylor M
Year: 2011
Journal: Gastroenterology
Title: Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice.
Volume: 140
Issue: 7
Pages: 2044-55
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Publication
25751063 | J:222097
First Author: Albers J
Year: 2015
Journal: J Clin Invest
Title: A versatile modular vector system for rapid combinatorial mammalian genetics.
Volume: 125
Issue: 4
Pages: 1603-19
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•
•
Publication
26054543 | J:293573
First Author: Souma T
Year: 2016
Journal: J Am Soc Nephrol
Title: Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling.
Volume: 27
Issue: 2
Pages: 428-38
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Publication
34661337 | J:318688
First Author: Nishikawa K
Year: 2021
Journal: EMBO Rep
Title: Osteoclasts adapt to physioxia perturbation through DNA demethylation.
Volume: 22
Issue: 12
Pages: e53035
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Publication
29671738 | J:264165
   
First Author: Macias D
Year: 2018
Journal: Elife
Title: HIF-2α is essential for carotid body development and function.
Volume: 7
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Publication
29074488 | J:258206
First Author: Tang H
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.
Volume: 314
Issue: 2
Pages: L256-L275
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Publication
27565342 | J:234541
First Author: Clever D
Year: 2016
Journal: Cell
Title: Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Volume: 166
Issue: 5
Pages: 1117-1131.e14
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Publication
23563312 | J:201460
First Author: Hanna SC
Year: 2013
Journal: J Clin Invest
Title: HIF1α and HIF2α independently activate SRC to promote melanoma metastases.
Volume: 123
Issue: 5
Pages: 2078-93
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Publication
35216965 | J:350085
First Author: Garcia Garcia CJ
Year: 2022
Journal: Gastroenterology
Title: Stromal HIF2 Regulates Immune Suppression in the Pancreatic Cancer Microenvironment.
Volume: 162
Issue: 7
Pages: 2018-2031
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Publication
21217667 | J:168583
First Author: Araldi E
Year: 2011
Journal: Nat Med
Title: Lack of HIF-2α in limb bud mesenchyme causes a modest and transient delay of endochondral bone development.
Volume: 17
Issue: 1
Pages: 25-6; author reply 27-9
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