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Search results 2801 to 2900 out of 7122 for App

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Strain
MGI:6304947 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD14/TyJ)F1/J
Attribute String: transgenic, mutant strain, F1 hybrid
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Strain
MGI:6305867 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD99/RwwJ)F1/J
Attribute String: transgenic, F1 hybrid
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Strain
MGI:6304944 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x DBA/2J)F1/J
Attribute String: F1 hybrid, mutant strain, transgenic
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Strain
MGI:6305868 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD100/RwwJ)F1/J
Attribute String: F1 hybrid, transgenic
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Strain
MGI:6304945 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD32/TyJ)F1/J
Attribute String: transgenic, mutant strain, F1 hybrid
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Strain
MGI:5629841 | B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas Tg(Prnp-MAPT*P301S)PS19Vle
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:6305865 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD81/RwwJ)F1/J
Attribute String: transgenic, F1 hybrid
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Strain
MGI:6305866 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD87/RwwJ)F1/J
Attribute String: F1 hybrid, transgenic
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Strain
MGI:3699172 | B6SJL-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax
Attribute String: mutant stock, transgenic
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Strain
MGI:5755042 | B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:3811801 | B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax
Attribute String: congenic, transgenic
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Strain
MGI:6305840 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD16/TyJ)F1/J
Attribute String: transgenic, F1 hybrid
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Strain
MGI:6305841 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD22/TyJ)F1/J
Attribute String: F1 hybrid, transgenic
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Strain
MGI:6305832 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD2/TyJ)F1/J
Attribute String: F1 hybrid, transgenic
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Strain
MGI:7857091 | B6N.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Kan
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:6305849 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD60/RwwJ)F1/J
Attribute String: F1 hybrid, transgenic
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Strain
MGI:6305850 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD61/RwwJ)F1/J
Attribute String: transgenic, F1 hybrid
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Strain
MGI:6305848 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD56/RwwJ)F1/J
Attribute String: transgenic, F1 hybrid
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Strain
MGI:6305844 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD51/RwwJ)F1/J
Attribute String: transgenic, F1 hybrid
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Strain
MGI:6305845 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD55/RwwJ)F1/J
Attribute String: F1 hybrid, transgenic
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Strain
MGI:6305842 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD42/TyJ)F1/J
Attribute String: transgenic, F1 hybrid
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MGI:6305843 | (B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax x BXD44/RwwJ)F1/J
Attribute String: F1 hybrid, transgenic
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Publication
37944529 | J:358291
First Author: Tsitsou-Kampeli A
Year: 2023
Journal: Cell Rep Med
Title: Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis.
Volume: 4
Issue: 11
Pages: 101278
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Publication
30205359 | J:271667
 
First Author: Fainstein N
Year: 2018
Journal: Neurobiol Aging
Title: Resident brain neural precursor cells develop age-dependent loss of therapeutic functions in Alzheimer's mice.
Volume: 72
Pages: 40-52
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Publication
38178803 | J:350120
First Author: Francis JS
Year: 2024
Journal: J Neurochem
Title: Over-expression of N-acetylaspartate synthase exacerbates pathological energetic deficit and accelerates cognitive decline in the 5xFAD mouse.
Volume: 168
Issue: 2
Pages: 69-82
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Publication
30055208 | J:284800
 
First Author: Story D
Year: 2019
Journal: Behav Brain Res
Title: Latency to startle is increased in the 5xFAD mouse model of Alzheimer’s disease.
Volume: 359
Pages: 823-827
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Publication
37261266 | J:346321
 
First Author: Zhukov O
Year: 2023
Journal: Front Aging Neurosci
Title: Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer's disease.
Volume: 15
Pages: 1089005
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Publication
38238311 | J:351128
First Author: Paudel B
Year: 2024
Journal: Nat Commun
Title: Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer's disease and aging.
Volume: 15
Issue: 1
Pages: 264
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Publication
38036733 | J:351127
First Author: Choi H
Year: 2023
Journal: Exp Mol Med
Title: Spatiotemporal characterization of glial cell activation in an Alzheimer's disease model by spatially resolved transcriptomics.
Volume: 55
Issue: 12
Pages: 2564-2575
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Publication
31358858 | J:284802
First Author: Soudy R
Year: 2019
Journal: Sci Rep
Title: Short amylin receptor antagonist peptides improve memory deficits in Alzheimer's disease mouse model.
Volume: 9
Issue: 1
Pages: 10942
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Publication
23747045 | J:211723
First Author: Saul A
Year: 2013
Journal: Neurobiol Aging
Title: Accelerated tau pathology with synaptic and neuronal loss in a novel triple transgenic mouse model of Alzheimer's disease.
Volume: 34
Issue: 11
Pages: 2564-73
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Publication
31413350 | J:284803
First Author: Lee HJ
Year: 2019
Journal: Sci Rep
Title: Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice.
Volume: 9
Issue: 1
Pages: 11814
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Publication
37770712 | J:350132
First Author: Zhang P
Year: 2023
Journal: Nat Methods
Title: Deep learning-driven adaptive optics for single-molecule localization microscopy.
Volume: 20
Issue: 11
Pages: 1748-1758
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Publication
31358793 | J:284804
First Author: Carreras I
Year: 2019
Journal: Sci Rep
Title: Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 10972
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Publication
38036718 | J:350171
First Author: Bowen ER
Year: 2023
Journal: Discov Ment Health
Title: Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease.
Volume: 3
Issue: 1
Pages: 27
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Publication
33649346 | J:305219
First Author: Svensson M
Year: 2021
Journal: Sci Rep
Title: The effect of electroconvulsive therapy on neuroinflammation, behavior and amyloid plaques in the 5xFAD mouse model of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 4910
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Publication
35921534 | J:350179
First Author: Zhao P
Year: 2022
Journal: MAbs
Title: Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice.
Volume: 14
Issue: 1
Pages: 2107971
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Publication
30472115 | J:284805
First Author: Boeddrich A
Year: 2019
Journal: Cell Chem Biol
Title: The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice.
Volume: 26
Issue: 1
Pages: 109-120.e7
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Publication
30576233 | J:284806
First Author: Qian Q
Year: 2019
Journal: FASEB J
Title: Down-regulated expression of microRNA-338-5p contributes to neuropathology in Alzheimer's disease.
Volume: 33
Issue: 3
Pages: 4404-4417
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Publication
31602409 | J:284807
 
First Author: Gail Canter R
Year: 2019
Journal: Commun Biol
Title: 3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice.
Volume: 2
Pages: 360
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Publication
30859123 | J:284808
 
First Author: Duncan MJ
Year: 2019
Journal: Alzheimers Dement (N Y)
Title: Effects of the dual orexin receptor antagonist DORA-22 on sleep in 5XFAD mice.
Volume: 5
Pages: 70-80
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Publication
33649406 | J:305221
First Author: McAnany JJ
Year: 2021
Journal: Sci Rep
Title: Rod pathway and cone pathway retinal dysfunction in the 5xFAD mouse model of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 4824
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Publication
31570178 | J:284809
 
First Author: Lee M
Year: 2019
Journal: Neurobiol Aging
Title: Age dependency of mGluR5 availability in 5xFAD mice measured by PET.
Volume: 84
Pages: 208-216
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Publication
31934509 | J:284810
 
First Author: Haugen ØP
Year: 2020
Journal: PeerJ
Title: Blood lactate dynamics in awake and anaesthetized mice after intraperitoneal and subcutaneous injections of lactate-sex matters.
Volume: 8
Pages: e8328
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Publication
31259073 | J:284811
First Author: Nguyen D
Year: 2019
Journal: Biomed Opt Express
Title: Supervised learning to quantify amyloidosis in whole brains of an Alzheimer's disease mouse model acquired with optical projection tomography.
Volume: 10
Issue: 6
Pages: 3041-3060
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Publication
26626428 | J:284812
 
First Author: Antonios G
Year: 2015
Journal: Sci Rep
Title: Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X.
Volume: 5
Pages: 17338
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Publication
36749986 | J:350144
First Author: Liang C
Year: 2023
Journal: Synapse
Title: Abnormal [(18) F]NIFENE binding in transgenic 5xFAD mouse model of Alzheimer's disease: In vivo PET/CT imaging studies of α4β2* nicotinic acetylcholinergic receptors and in vitro correlations with Aβ plaques.
Volume: 77
Issue: 3
Pages: e22265
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Publication
23810804 | J:201685
 
First Author: Zhao H
Year: 2013
Journal: Neurosci Lett
Title: Hyperphosphorylation of tau protein by calpain regulation in retina of Alzheimer's disease transgenic mouse.
Volume: 551
Pages: 12-6
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Publication
27225182 | J:249709
First Author: Kumar DK
Year: 2016
Journal: Sci Transl Med
Title: Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease.
Volume: 8
Issue: 340
Pages: 340ra72
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Publication
28655608 | J:249708
 
First Author: Mast N
Year: 2017
Journal: Neuropharmacology
Title: Cholesterol-metabolizing enzyme cytochrome P450 46A1 as a pharmacologic target for Alzheimer's disease.
Volume: 123
Pages: 465-476
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Publication
28844596 | J:249707
 
First Author: Baranger K
Year: 2017
Journal: Neuropharmacology
Title: Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease.
Volume: 126
Pages: 128-141
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Publication
28890389 | J:249706
 
First Author: O'Leary TP
Year: 2018
Journal: Behav Brain Res
Title: Motor function deficits in the 12 month-old female 5xFAD mouse model of Alzheimer's disease.
Volume: 337
Pages: 256-263
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Publication
28697378 | J:249710
 
First Author: Wendt S
Year: 2017
Journal: Neurobiol Aging
Title: Changes in phagocytosis and potassium channel activity in microglia of 5xFAD mice indicate alterations in purinergic signaling in a mouse model of Alzheimer's disease.
Volume: 58
Pages: 41-53
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Publication
25156412 | J:217828
First Author: Moon M
Year: 2015
Journal: J Neurochem
Title: Correlation between orphan nuclear receptor Nurr1 expression and amyloid deposition in 5XFAD mice, an animal model of Alzheimer's disease.
Volume: 132
Issue: 2
Pages: 254-62
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Publication
27785640 | J:350192
First Author: Spencer NG
Year: 2017
Journal: MAGMA
Title: Can MRI T(1) be used to detect early changes in 5xFAD Alzheimer's mouse brain?
Volume: 30
Issue: 2
Pages: 153-163
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Publication
36250342 | J:350159
First Author: LLabre JE
Year: 2022
Journal: J Bone Miner Res
Title: Degradation of Bone Quality in a Transgenic Mouse Model of Alzheimer's Disease.
Volume: 37
Issue: 12
Pages: 2548-2565
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Publication
24586789 | J:213824
First Author: Bhattacharya S
Year: 2014
Journal: PLoS One
Title: Galantamine slows down plaque formation and behavioral decline in the 5XFAD mouse model of Alzheimer's disease.
Volume: 9
Issue: 2
Pages: e89454
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Publication
32522622 | J:307432
 
First Author: O'Leary TP
Year: 2020
Journal: Behav Brain Res
Title: Intact olfactory memory in the 5xFAD mouse model of Alzheimer's disease from 3 to 15 months of age.
Volume: 393
Pages: 112731
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Publication
31743728 | J:307433
 
First Author: Peterman JL
Year: 2020
Journal: Behav Brain Res
Title: Prolonged isolation stress accelerates the onset of Alzheimer's disease-related pathology in 5xFAD mice despite running wheels and environmental enrichment.
Volume: 379
Pages: 112366
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Publication
27911291 | J:350198
First Author: Hilt S
Year: 2017
Journal: J Alzheimers Dis
Title: A Metal-Free Method for Producing MRI Contrast at Amyloid-β.
Volume: 55
Issue: 4
Pages: 1667-1681
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Publication
32479996 | J:292791
 
First Author: Casali BT
Year: 2020
Journal: Neurobiol Dis
Title: Microglia depletion rapidly and reversibly alters amyloid pathology by modification of plaque compaction and morphologies.
Volume: 142
Pages: 104956
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Publication
37604976 | J:350200
First Author: Zhang Y
Year: 2023
Journal: Mol Psychiatry
Title: Transmission of Alzheimer's disease-associated microbiota dysbiosis and its impact on cognitive function: evidence from mice and patients.
Volume: 28
Issue: 10
Pages: 4421-4437
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Publication
36913892 | J:334492
 
First Author: Cho E
Year: 2023
Journal: Biomed Pharmacother
Title: Phyllodulcin improves hippocampal long-term potentiation in 5XFAD mice.
Volume: 161
Pages: 114511
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Publication
37614669 | J:350201
First Author: Yang EJ
Year: 2023
Journal: PNAS Nexus
Title: Transient anxiety-and depression-like behaviors are linked to the depletion of Foxp3-expressing cells via inflammasome in the brain.
Volume: 2
Issue: 8
Pages: pgad251
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Publication
37942288 | J:350215
 
First Author: Yeo S
Year: 2023
Journal: Front Mol Biosci
Title: Primary cilia-mediated regulation of microglial secretion in Alzheimer's disease.
Volume: 10
Pages: 1250335
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Publication
38572427 | J:347653
 
First Author: Puris E
Year: 2024
Journal: Front Pharmacol
Title: Sex-specific changes in protein expression of membrane transporters in the brain cortex of 5xFAD mouse model of Alzheimer's disease.
Volume: 15
Pages: 1365051
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Publication
35814256 | J:326853
 
First Author: Li XW
Year: 2022
Journal: Front Pharmacol
Title: Mechanism of Neural Regeneration Induced by Natural Product LY01 in the 5×FAD Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 926123
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Publication
30483077 | J:276320
 
First Author: Kang S
Year: 2018
Journal: Front Behav Neurosci
Title: Effects of a Dehydroevodiamine-Derivative on Synaptic Destabilization and Memory Impairment in the 5xFAD, Alzheimer's Disease Mouse Model.
Volume: 12
Pages: 273
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Publication
39444645 | J:359207
 
First Author: Doolen S
Year: 2023
Journal: F1000Res
Title: Validation and in vivo characterization of research antibodies for Moesin, CD44, Midkine, and sFRP-1.
Volume: 12
Pages: 1070
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Publication
39273422 | J:354300
 
First Author: Ianni M
Year: 2024
Journal: Int J Mol Sci
Title: Spatiotemporal Dysregulation of Neuron-Glia Related Genes and Pro-/Anti-Inflammatory miRNAs in the 5xFAD Mouse Model of Alzheimer's Disease.
Volume: 25
Issue: 17
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Publication
35850693 | J:326882
First Author: Choi HJ
Year: 2022
Journal: Mol Brain
Title: Donepezil ameliorates Aβ pathology but not tau pathology in 5xFAD mice.
Volume: 15
Issue: 1
Pages: 63
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Publication
39238036 | J:359213
First Author: Sakimura K
Year: 2024
Journal: Alzheimers Res Ther
Title: A novel PDHK inhibitor restored cognitive dysfunction and limited neurodegeneration without affecting amyloid pathology in 5xFAD mouse, a model of Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 197
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Publication
38513667 | J:347663
     
First Author: Zhang D
Year: 2024
Journal: Neuron
Title: P-tau217 correlates with neurodegeneration in Alzheimer's disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy.
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Publication
34946148 | J:350224
 
First Author: Valeri F
Year: 2021
Journal: Microorganisms
Title: Impact of the Age of Cecal Material Transfer Donors on Alzheimer's Disease Pathology in 5xFAD Mice.
Volume: 9
Issue: 12
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Publication
38145360 | J:350220
First Author: Awasthi R
Year: 2024
Journal: Adv Biol (Weinh)
Title: Reversing Aging: Decline in Complex Olfactory Learning Can be Rectified by Restoring Intrinsic Plasticity of Hippocampal CA1 Pyramidal Neurons.
Volume: 8
Issue: 3
Pages: e2300323
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Publication
38153668 | J:350221
First Author: Mensah-Kane P
Year: 2024
Journal: Geroscience
Title: Hyperbaric oxygen alleviates selective domains of cognitive and motor deficits in female 5xFAD mice.
Volume: 46
Issue: 1
Pages: 517-530
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Publication
33584248 | J:351272
 
First Author: Molina-Martínez P
Year: 2020
Journal: Front Aging Neurosci
Title: Microglial Hyperreactivity Evolved to Immunosuppression in the Hippocampus of a Mouse Model of Accelerated Aging and Alzheimer's Disease Traits.
Volume: 12
Pages: 622360
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Publication
24485508 | J:213882
First Author: Baik SH
Year: 2014
Journal: Neurobiol Aging
Title: Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model.
Volume: 35
Issue: 6
Pages: 1286-92
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Publication
38915309 | J:350237
 
First Author: Jaye S
Year: 2024
Journal: Front Neurosci
Title: A clathrin mediated endocytosis scaffolding protein, Intersectin 1, changes in an isoform, brain region, and sex specific manner in Alzheimer's disease.
Volume: 18
Pages: 1426180
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Publication
37717663 | J:341177
 
First Author: Medina-Vera D
Year: 2023
Journal: Neurobiol Dis
Title: Transcending the amyloid-beta dominance paradigm in Alzheimer's disease: An exploration of behavioural, metabolic, and gut microbiota phenotypes in 5xFAD mice.
Volume: 187
Pages: 106295
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Publication
37276426 | J:357342
First Author: Ennerfelt H
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: CARD9 attenuates Aβ pathology and modifies microglial responses in an Alzheimer's disease mouse model.
Volume: 120
Issue: 24
Pages: e2303760120
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Publication
38928221 | J:350239
 
First Author: Lopes FBTP
Year: 2024
Journal: Int J Mol Sci
Title: Methionine Sulfoxide Speciation in Mouse Hippocampus Revealed by Global Proteomics Exhibits Age- and Alzheimer's Disease-Dependent Changes Targeted to Mitochondrial and Glycolytic Pathways.
Volume: 25
Issue: 12
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Publication
19026746 | J:144743
First Author: Kimura R
Year: 2009
Journal: Neurobiol Dis
Title: Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model.
Volume: 33
Issue: 2
Pages: 229-35
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Publication
23155049 | J:193739
First Author: Avrahami L
Year: 2013
Journal: J Biol Chem
Title: Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies.
Volume: 288
Issue: 2
Pages: 1295-306
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Publication
38714691 | J:348052
First Author: Keiser AA
Year: 2024
Journal: Nat Commun
Title: Specific exercise patterns generate an epigenetic molecular memory window that drives long-term memory formation and identifies ACVR1C as a bidirectional regulator of memory in mice.
Volume: 15
Issue: 1
Pages: 3836
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Publication
38061987 | J:350302
First Author: Darvesh S
Year: 2023
Journal: J Enzyme Inhib Med Chem
Title: A method for the efficient evaluation of substrate-based cholinesterase imaging probes for Alzheimer's disease.
Volume: 38
Issue: 1
Pages: 2225797
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Publication
36959514 | J:338491
First Author: Mi Y
Year: 2023
Journal: Nat Metab
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