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Search results 501 to 600 out of 649 for Prdm16

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Type Details Score
Publication
29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
- | J:72245
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Prdm16os<+> | MGI:3662426
 
Name: Prdm16 opposite strand transcript; wild type
Allele Type: Not Specified
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Protein
A2A929
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: true
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Protein
A2A935
Organism: Mus musculus/domesticus
Length: 1275  
Fragment?: false
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Protein
A2A931
Organism: Mus musculus/domesticus
Length: 1274  
Fragment?: false
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Protein
A2A933
Organism: Mus musculus/domesticus
Length: 1276  
Fragment?: false
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Protein
A2A930
Organism: Mus musculus/domesticus
Length: 1257  
Fragment?: false
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Protein
A2A934
Organism: Mus musculus/domesticus
Length: 1177  
Fragment?: false
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HT Experiment
GSE159728 | RNA-Seq of E14 MGE, Prdm16 WT vs cKO
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
A2A935-3
Organism: Mus musculus/domesticus
Length: 1276  
Fragment?: false
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Protein
A2A935-2
Organism: Mus musculus/domesticus
Length: 1178  
Fragment?: false
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ncRNA Gene
MGP_CAROLIEiJ_G0003614 | -
Type: ncRNA_gene
Organism: Mus caroli
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ncRNA Gene
MGP_129S1SvImJ_G0004017 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_AJ_G0003998 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_AKRJ_G0003975 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_BALBcJ_G0003984 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_C3HHeJ_G0003931 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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Antisense lncRNA Gene
MGI_C57BL6J_3651882 | -
Type: antisense_lncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_C57BL6NJ_G0004133 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CASTEiJ_G0003894 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CBAJ_G0003924 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_DBA2J_G0003940 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_FVBNJ_G0003959 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_LPJ_G0004020 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_NODShiLtJ_G0003947 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_NZOHlLtJ_G0004127 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_PWKPhJ_G0003848 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_WSBEiJ_G0003930 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_PahariEiJ_G0003833 | -
Type: ncRNA_gene
Organism: Mus pahari
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ncRNA Gene
MGP_SPRETEiJ_G0003793 | -
Type: ncRNA_gene
Organism: Mus spretus
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Publication
29626186 | J:269596
First Author: Ding C
Year: 2018
Journal: Nat Commun
Title: De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis.
Volume: 9
Issue: 1
Pages: 1329
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HT Experiment
GSE111660 | Transcriptome profiling of WT and Prdm16 mutant cells in embryonic mouse cerebral cortex.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-GEOD-23406 | Prdm16 newborn mouse (ventricular zone) VZ cells microarray
Series Id: GSE23406
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE162854 | PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE142684 | RNA-seq analysis of Wildtype and Prdm16 cKO ventricular zone tissue during cortex development in mouse
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE193046 | The impact of Prdm16 deletion on the transcriptome of the developing cochlear duct cells
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE179386 | PRDM16 Functions as A Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle (bulk RNA-seq)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE179390 | PRDM16 Functions as A Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle (scRNA-seq)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Tg(Fabp4-Prdm16)T1Brsp | MGI:5562569
Name: transgene insertion T1, Bruce M Spiegelman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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DO Term
DOID:0081157 | dilated cardiomyopathy 1LL
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Publication
25578880 | J:218161
First Author: Dempersmier J
Year: 2015
Journal: Mol Cell
Title: Cold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat.
Volume: 57
Issue: 2
Pages: 235-46
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GXD Expression
GXD Expression
Probe: MGI:7581887
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7581990
Age: embryonic day 13.5
Image: 1B E13.5
Note: Partial overlap of expression with Prdm16 was noted in the region of inner supporting cells.
Specimen Label: 1B E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7581887
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7581990
Age: embryonic day 14.5
Image: 1B E14.5
Note: Partial overlap of expression with Prdm16 was noted in the region of inner supporting cells.
Specimen Label: 1B E14.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7581887
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7581990
Age: embryonic day 15.5
Image: 1B E15.5
Note: Partial overlap of expression with Prdm16 was noted in the region of inner supporting cells.
Specimen Label: 1B E15.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7581887
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759724
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7581990
Age: embryonic day 16.5
Image: 1B E16.5
Note: Partial overlap of expression with Prdm16 was noted in the region of inner supporting cells.
Specimen Label: 1B E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7581887
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7581990
Age: embryonic day 18.5
Image: 1B E18.5
Note: Partial overlap of expression with Prdm16 was noted in the region of inner supporting cells.
Specimen Label: 1B E18.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:7581887
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7581990
Age: postnatal day 0
Image: 1B P0
Note: Partial overlap of expression with Prdm16 was noted in the region of inner supporting cells.
Specimen Label: 1B P0
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7581887
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7581990
Age: postnatal day 3
Image: 1B P3
Note: Partial overlap of expression with Prdm16 was noted in the region of inner supporting cells.
Specimen Label: 1B P3
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:7581887
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7581990
Age: postnatal day 7
Image: 1B P7
Note: Partial overlap of expression with Prdm16 was noted in the region of inner supporting cells.
Specimen Label: 1B P7
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:7384695
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7384935
Age: embryonic day 12.5
Image: 2I
Note: Expression in mesenchyme lateral to epaxial myotome, colocalized with Prdm16 expression.
Specimen Label: 2I
Detected: true
Specimen Num: 9
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Allele
Prdm16<em1Smoc> | MGI:7291788
Name: PR domain containing 16; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
30462309 | -
     
First Author: Ivanochko D
Year: 2018
Journal: Nucleic Acids Res
Title: Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.
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Publication
26876562 | J:233027
First Author: Svensson KJ
Year: 2016
Journal: Cell Metab
Title: A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function.
Volume: 23
Issue: 3
Pages: 454-66
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Allele
Prdm16<tm1.1Bjo> | MGI:7541323
Name: PR domain containing 16; targeted mutation 1.1, Bryan C Bjork
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
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Protein Domain
IPR044410 | PRDM16_PR-SET
Type: Domain
Description: This entry represents the PR/SET domain found in PR domain zinc finger protein 16 (PRDM16, also known as MEL1). PRDM16 and PRDM3 share protein sequences similarities and have functions in hematopoietic and neuronal stem cells and in adipose tissue differentiation. They also act as oncoproteins (Mel1 and Evi1) involved in translocation-induced leukemia. PRDM3 and PRDM16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity [, , ].The PRDM family members are characterised by the presence of a N-terminal PR (PRDI-BF1 and RIZ1 homology) domain followed by multiple zinc fingers which confer DNA binding activity. PR domains are only distantly related to the classical SET methyltransferase domains []. They are involved in epigenetic regulation of gene expression through their intrinsic histone methyltransferase activity or via interactions with other chromatin modifying enzymes [].
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Protein Domain
IPR044411 | PRDM3_PR-SET
Type: Domain
Description: This entry represents the PR/SET domain found in PR domain zinc finger protein 3 (PRDM3, also known as MECOM or EVI-1). PRDM3 and PRDM16 share protein sequences similarities and have functions in hematopoietic and neuronal stem cells and in adipose tissue differentiation. They also act as oncoproteins (Mel1 and Evi1) involved in translocation-induced leukemia. PRDM3 and PRDM16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity [].The PRDM family members are characterised by the presence of a N-terminal PR (PRDI-BF1 and RIZ1 homology) domain followed by multiple zinc fingers which confer DNA binding activity. PR domains are only distantly related to the classical SET methyltransferase domains []. They are involved in epigenetic regulation of gene expression through their intrinsic histone methyltransferase activity or via interactions with other chromatin modifying enzymes [].
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HT Experiment
E-MTAB-1704 | RNA-seq of coding RNA of brown adipose tissue from Ehmt1flox/flox control mice, Ehmt1Myf5 Knockout mice and Ehmt1adipo knockout mice to study the role of euchromatic histone-lysine N-methyltransferase 1 (EHMT1)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
25205686 | J:217555
First Author: Choi MC
Year: 2014
Journal: EMBO Rep
Title: HDAC4 promotes Pax7-dependent satellite cell activation and muscle regeneration.
Volume: 15
Issue: 11
Pages: 1175-83
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Publication
29131158 | J:251812
First Author: Ikeda K
Year: 2017
Journal: Nat Med
Title: UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis.
Volume: 23
Issue: 12
Pages: 1454-1465
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