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Search results 1 to 100 out of 111 for Pknox1

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Type Details Score
Publication
- | J:63795
   
First Author: Nakamura T
Year: 1998
Journal: GenBank Submission
Title: Mus musculus homeobox protein PKNOX1 (Pknox1) mRNA, complete cds
Pages: AF061270
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Publication
9405651 | J:45106
First Author: Knoepfler PS
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1.
Volume: 94
Issue: 26
Pages: 14553-8
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Publication
29293683 | J:258387
First Author: Kawai Y
Year: 2018
Journal: PLoS One
Title: Germ cell-intrinsic requirement for the homeodomain transcription factor PKnox1/Prep1 in adult spermatogenesis.
Volume: 13
Issue: 1
Pages: e0190702
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Publication
24216763 | J:207764
First Author: Kanzleiter T
Year: 2014
Journal: Mol Cell Biol
Title: Pknox1/Prep1 regulates mitochondrial oxidative phosphorylation components in skeletal muscle.
Volume: 34
Issue: 2
Pages: 290-8
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Publication
29474930 | J:262292
First Author: Liotti A
Year: 2018
Journal: Biochim Biophys Acta
Title: Prep1 deficiency improves metabolic response in white adipose tissue.
Volume: 1863
Issue: 5
Pages: 515-525
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Publication
30604852 | J:267951
First Author: Sicouri L
Year: 2018
Journal: Int J Dev Biol
Title: Prep1 (pKnox1) transcription factor contributes to pubertal mammary gland branching morphogenesis.
Volume: 62
Issue: 11-12
Pages: 827-836
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Publication
25233378 | J:220635
First Author: Modica L
Year: 2014
Journal: PLoS One
Title: Prep1 (pKnox1) regulates mouse embryonic HSC cycling and self-renewal affecting the Stat1-Sca1 IFN-dependent pathway.
Volume: 9
Issue: 9
Pages: e107916
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Publication
20864515 | J:170202
First Author: Oriente F
Year: 2011
Journal: Diabetes
Title: Prep1 controls insulin glucoregulatory function in liver by transcriptional targeting of SHP1 tyrosine phosphatase.
Volume: 60
Issue: 1
Pages: 138-47
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Publication
34679197 | J:323047
First Author: Cimmino I
Year: 2021
Journal: FASEB J
Title: Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging.
Volume: 35
Issue: 11
Pages: e21989
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Publication
16314502 | J:103769
First Author: Penkov D
Year: 2005
Journal: Mol Cell Biol
Title: Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors.
Volume: 25
Issue: 24
Pages: 10768-81
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Publication
26285139 | J:242880
First Author: Yoshioka K
Year: 2015
Journal: PLoS One
Title: Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.
Volume: 10
Issue: 8
Pages: e0136107
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Publication
21715654 | J:174386
First Author: Iotti G
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Homeodomain transcription factor and tumor suppressor Prep1 is required to maintain genomic stability.
Volume: 108
Issue: 29
Pages: E314-22
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Publication
9479508 | J:45952
First Author: Berthelsen J
Year: 1998
Journal: Genomics
Title: PKNOX1, a gene encoding PREP1, a new regulator of Pbx activity, maps on human chromosome 21q22.3 and murine chromosome 17B/C.
Volume: 47
Issue: 2
Pages: 323-4
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Publication
20110257 | J:173148
First Author: Micali N
Year: 2010
Journal: Nucleic Acids Res
Title: Down syndrome fibroblasts and mouse Prep1-overexpressing cells display increased sensitivity to genotoxic stress.
Volume: 38
Issue: 11
Pages: 3595-604
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Publication
25157139 | J:216398
First Author: Risolino M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma.
Volume: 111
Issue: 36
Pages: E3775-84
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Publication
25875616 | J:233494
First Author: Laurent A
Year: 2015
Journal: PLoS One
Title: ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells.
Volume: 10
Issue: 4
Pages: e0122518
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Publication
19103748 | J:145727
First Author: Micali N
Year: 2009
Journal: Mol Cell Biol
Title: Prep1 directly regulates the intrinsic apoptotic pathway by controlling Bcl-XL levels.
Volume: 29
Issue: 5
Pages: 1143-51
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Publication
18644868 | J:140357
First Author: Oriente F
Year: 2008
Journal: Mol Cell Biol
Title: Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism.
Volume: 28
Issue: 18
Pages: 5634-45
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Publication
17875925 | J:133010
First Author: Yoshioka H
Year: 2007
Journal: Mol Cell Biol
Title: In vivo analysis of developmentally and evolutionarily dynamic protein-DNA interactions regulating transcription of the Pgk2 gene during mammalian spermatogenesis.
Volume: 27
Issue: 22
Pages: 7871-85
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Publication
27815072 | J:241155
First Author: Kulebyakin K
Year: 2016
Journal: Biochem Biophys Res Commun
Title: The transcription factor Prep1 controls hepatic insulin sensitivity and gluconeogenesis by targeting nuclear localization of FOXO1.
Volume: 481
Issue: 1-2
Pages: 182-188
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Publication
29138456 | J:323705
First Author: Maroni G
Year: 2017
Journal: Sci Rep
Title: Prep1 prevents premature adipogenesis of mesenchymal progenitors.
Volume: 7
Issue: 1
Pages: 15573
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Publication
23133585 | J:192251
First Author: Iotti G
Year: 2012
Journal: PLoS One
Title: Reduction of Prep1 levels affects differentiation of normal and malignant B cells and accelerates Myc driven lymphomagenesis.
Volume: 7
Issue: 10
Pages: e48353
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Publication
24052111 | J:204065
First Author: Oriente F
Year: 2013
Journal: Diabetologia
Title: PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice.
Volume: 56
Issue: 12
Pages: 2713-22
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Publication
18560600 | J:137206
First Author: Penkov D
Year: 2008
Journal: PLoS One
Title: Cytosolic sequestration of Prep1 influences early stages of T cell development.
Volume: 3
Issue: 6
Pages: e2424
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Publication
12412021 | J:80127
First Author: Haller K
Year: 2002
Journal: Dev Dyn
Title: Prep2: cloning and expression of a new prep family member.
Volume: 225
Issue: 3
Pages: 358-64
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Publication
17904118 | J:127523
First Author: Di Rosa P
Year: 2007
Journal: Dev Biol
Title: The homeodomain transcription factor Prep1 (pKnox1) is required for hematopoietic stem and progenitor cell activity.
Volume: 311
Issue: 2
Pages: 324-34
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Publication
24809472 | J:216083
First Author: Dardaei L
Year: 2014
Journal: PLoS One
Title: The deficiency of tumor suppressor prep1 accelerates the onset of meis1- hoxa9 leukemogenesis.
Volume: 9
Issue: 5
Pages: e96711
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Publication
24578510 | J:207399
First Author: Dardaei L
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis.
Volume: 111
Issue: 10
Pages: E896-905
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10373562 | J:55892
First Author: Jacobs Y
Year: 1999
Journal: Mol Cell Biol
Title: Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity.
Volume: 19
Issue: 7
Pages: 5134-42
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Publication
17875935 | J:129037
First Author: Díaz VM
Year: 2007
Journal: Mol Cell Biol
Title: p160 Myb-binding protein interacts with Prep1 and inhibits its transcriptional activity.
Volume: 27
Issue: 22
Pages: 7981-90
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19365557 | J:148277
First Author: Villaescusa JC
Year: 2009
Journal: PLoS One
Title: Cytoplasmic Prep1 interacts with 4EHP inhibiting Hoxb4 translation.
Volume: 4
Issue: 4
Pages: e5213
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Publication
16705164 | J:334340
First Author: Zubair M
Year: 2006
Journal: Mol Cell Biol
Title: Two-step regulation of Ad4BP/SF-1 gene transcription during fetal adrenal development: initiation by a Hox-Pbx1-Prep1 complex and maintenance via autoregulation by Ad4BP/SF-1.
Volume: 26
Issue: 11
Pages: 4111-21
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Publication
18093541 | J:129168
First Author: Chung EY
Year: 2007
Journal: Immunity
Title: Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1.
Volume: 27
Issue: 6
Pages: 952-64
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Publication
18417536 | J:173069
First Author: Lampe X
Year: 2008
Journal: Nucleic Acids Res
Title: An ultraconserved Hox-Pbx responsive element resides in the coding sequence of Hoxa2 and is active in rhombomere 4.
Volume: 36
Issue: 10
Pages: 3214-25
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Publication
29349576 | J:273691
First Author: Ricci S
Year: 2018
Journal: Mol Neurobiol
Title: Prep1 Deficiency Affects Olfactory Perception and Feeding Behavior by Impairing BDNF-TrkB Mediated Neurotrophic Signaling.
Volume: 55
Issue: 8
Pages: 6801-6815
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Publication
17178831 | J:118901
First Author: Shim S
Year: 2007
Journal: Mol Cell Biol
Title: Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon.
Volume: 27
Issue: 5
Pages: 1614-30
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Publication
20413611 | J:160146
First Author: Rowan S
Year: 2010
Journal: Genes Dev
Title: Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity.
Volume: 24
Issue: 10
Pages: 980-5
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10381567 | J:56023
First Author: Ferretti E
Year: 1999
Journal: Mech Dev
Title: The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse.
Volume: 83
Issue: 1-2
Pages: 53-64
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Publication
14764653 | J:89598
First Author: Bailey JS
Year: 2004
Journal: Mol Endocrinol
Title: Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1.
Volume: 18
Issue: 5
Pages: 1158-70
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Publication
22987645 | J:188111
First Author: Sonnet W
Year: 2012
Journal: Dev Dyn
Title: Characterization of TALE genes expression during the first lineage segregation in mammalian embryos.
Volume: 241
Issue: 11
Pages: 1827-39
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12183364 | J:78468
First Author: Zhang X
Year: 2002
Journal: Genes Dev
Title: Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.
Volume: 16
Issue: 16
Pages: 2097-107
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22240097 | J:182769
First Author: Carbe C
Year: 2012
Journal: Dev Biol
Title: The functional role of the Meis/Prep-binding elements in Pax6 locus during pancreas and eye development.
Volume: 363
Issue: 1
Pages: 320-9
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Publication
15087118 | J:89962
 
First Author: Villaescusa JC
Year: 2004
Journal: Gene
Title: Expression of Hox cofactor genes during mouse ovarian follicular development and oocyte maturation.
Volume: 330
Pages: 1-7
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Publication
16847320 | J:111418
First Author: Ferretti E
Year: 2006
Journal: Mol Cell Biol
Title: Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.
Volume: 26
Issue: 15
Pages: 5650-62
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Publication
17049510 | J:119671
First Author: Zhang X
Year: 2006
Journal: Dev Biol
Title: Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development.
Volume: 300
Issue: 2
Pages: 748-57
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Publication
18787068 | J:141247
First Author: Wassef MA
Year: 2008
Journal: Development
Title: Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors.
Volume: 135
Issue: 20
Pages: 3369-78
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Publication
22780989 | J:188795
First Author: Faure AJ
Year: 2012
Journal: Genome Res
Title: Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules.
Volume: 22
Issue: 11
Pages: 2163-75
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11707078 | J:69673
First Author: Davisson MT
Year: 2001
Journal: Genomics
Title: Evolutionary breakpoints on human chromosome 21.
Volume: 78
Issue: 1-2
Pages: 99-106
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23756022 | J:316267
First Author: Barber BA
Year: 2013
Journal: Ann Anat
Title: Dynamic expression of MEIS1 homeoprotein in E14.5 forebrain and differentiated forebrain-derived neural stem cells.
Volume: 195
Issue: 5
Pages: 431-40
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Publication
21982646 | J:178316
First Author: Ferretti E
Year: 2011
Journal: Dev Cell
Title: A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis.
Volume: 21
Issue: 4
Pages: 627-41
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20826531 | J:165811
First Author: Fernandez-Diaz LC
Year: 2010
Journal: Development
Title: The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells.
Volume: 137
Issue: 20
Pages: 3393-403
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Publication
18691704 | J:139570
First Author: Capellini TD
Year: 2008
Journal: Dev Biol
Title: Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome.
Volume: 321
Issue: 2
Pages: 500-14
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Publication
22748019 | J:185964
 
First Author: Sgadò P
Year: 2012
Journal: Neural Dev
Title: The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons.
Volume: 7
Pages: 24
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Publication
- | J:103485
     
First Author: Lexicon Genetics Inc
Year: 2005
Journal: MGI Direct Data Submission
Title: NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories
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Publication
19741146 | J:152838
First Author: Fu H
Year: 2009
Journal: J Neurosci
Title: A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.
Volume: 29
Issue: 36
Pages: 11399-408
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12466855 | J:80501
First Author: Gitton Y
Year: 2002
Journal: Nature
Title: A gene expression map of human chromosome 21 orthologues in the mouse.
Volume: 420
Issue: 6915
Pages: 586-90
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12466854 | J:80502
First Author: Reymond A
Year: 2002
Journal: Nature
Title: Human chromosome 21 gene expression atlas in the mouse.
Volume: 420
Issue: 6915
Pages: 582-6
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22174793 | J:182258
First Author: Taher L
Year: 2011
Journal: PLoS One
Title: Global gene expression analysis of murine limb development.
Volume: 6
Issue: 12
Pages: e28358
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9811942 | J:50869
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
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- | J:29126
     
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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29031500 | J:257654
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
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20932939 | J:168654
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
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10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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