| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Allele |
| Name: |
collagen, type I, alpha 1; targeted mutation 1, Nabil Djouder |
| Allele Type: |
Targeted |
| Attribute String: |
Humanized sequence, Inducible, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
URI1, prefoldin-like chaperone; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
collagen, type I, alpha 1; targeted mutation 2, Nabil Djouder |
| Allele Type: |
Targeted |
| Attribute String: |
Humanized sequence, Inducible, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
URI1, prefoldin-like chaperone; targeted mutation 2.1, Nabil Djouder |
| Allele Type: |
Targeted |
| Attribute String: |
Inducible, Null/knockout, Recombinase, Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Uri1/Uri1<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, transgenic, mutant strain, congenic |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Col1a1/Col1a1<+> Tg(Cebpb-tTA)#Bjd/? |
| Background: |
B6.Cg-Col1a1 Tg(Cebpb-tTA)#Bjd |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Col1a1/Col1a1 Tg(Cebpb-tTA)#Bjd/? |
| Background: |
B6.Cg-Col1a1 Tg(Cebpb-tTA)#Bjd |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Uri1/Uri1<+> |
| Background: |
involves: 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gomes AL |
| Year: |
2016 |
| Journal: |
Cancer Cell |
| Title: |
Metabolic Inflammation-Associated IL-17A Causes Non-alcoholic Steatohepatitis and Hepatocellular Carcinoma. |
| Volume: |
30 |
| Issue: |
1 |
| Pages: |
161-175 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Col1a1/Col1a1<+> Tg(Cebpb-tTA)#Bjd/? Trp53/Trp53<+> |
| Background: |
B6.Cg-Trp53 Col1a1 Tg(Cebpb-tTA)#Bjd |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(CAG-Katshuka)#Sgo/? Uri1/Uri1<+> |
| Background: |
involves: C57BL/6JOlaHsd * CBA/J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Markus SM |
| Year: |
2002 |
| Journal: |
Mol Biol Cell |
| Title: |
Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus. |
| Volume: |
13 |
| Issue: |
2 |
| Pages: |
670-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Silveira HC |
| Year: |
2004 |
| Journal: |
Braz J Med Biol Res |
| Title: |
A calcineurin inhibitory protein overexpressed in Down's syndrome interacts with the product of a ubiquitously expressed transcript. |
| Volume: |
37 |
| Issue: |
6 |
| Pages: |
785-9 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Ubiquitously expressed transcript protein UXT is involved in gene transcription regulation. It acts in concert with the corepressor URI1 to regulate androgen receptor transcription (AR). It is an AR N terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation []. It is a protein which interacts with the N terminus of the Down's syndrome candidate region 1 (DSCR1) protein, encoded by a gene located in the human chromosome 21. DSCR1 interacts with calcineurin and is overexpressed in Down's syndrome patients. UXT, which is encoded in human Xp11, is a 157-amino acid protein present in both cytosol and nucleus of the cells []. The members of this family are related to prefoldin, which is part of a molecular chaperone system that promotes the correct folding of nascent polypeptide chains. Prefoldin interacts with the nascent chain to stabilise it prior to its folding within the central cavity of a chaperonin. Prefoldin is a hexamer consisting of two types of subunits, alpha and beta. Archaeal prefoldin contains one type of alpha and one type of beta subunit [], while eukaryotic prefoldin contains two different but related alpha subunits and four related beta subunits []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tummala KS |
| Year: |
2017 |
| Journal: |
Cell Rep |
| Title: |
Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells. |
| Volume: |
19 |
| Issue: |
3 |
| Pages: |
584-600 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
157
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MartÃn-Benito J |
| Year: |
2002 |
| Journal: |
EMBO J |
| Title: |
Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT. |
| Volume: |
21 |
| Issue: |
23 |
| Pages: |
6377-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Siegert R |
| Year: |
2000 |
| Journal: |
Cell |
| Title: |
Structure of the molecular chaperone prefoldin: unique interaction of multiple coiled coil tentacles with unfolded proteins. |
| Volume: |
103 |
| Issue: |
4 |
| Pages: |
621-32 |
|
•
•
•
•
•
|