Rhodopsin kinase (also known as G-protein-coupled Receptor Kinase 1, GRK1) is a retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade []. Together with recoverin (a Ca2+-binding protein), GRK1 regulates cone phototransduction during photoreceptor light adaptation [, ].
Rhodopsin kinase (also known as G-protein-coupled Receptor Kinase 1, GRK1) is a retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade []. Together with recoverin (a Ca2+-binding protein), GRK1 regulates cone phototransduction during photoreceptor light adaptation [, ].This entry represents the catalytic domain of GRK1.
