Type |
Details |
Score |
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
152
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
174
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
971
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
595
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki N |
Year: |
2003 |
Journal: |
DNA Res |
Title: |
Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |
Volume: |
10 |
Issue: |
1 |
Pages: |
35-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schiraldi M |
Year: |
2012 |
Journal: |
J Exp Med |
Title: |
HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4. |
Volume: |
209 |
Issue: |
3 |
Pages: |
551-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heine H |
Year: |
1999 |
Journal: |
J Immunol |
Title: |
Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin. |
Volume: |
162 |
Issue: |
12 |
Pages: |
6971-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gohda J |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling. |
Volume: |
173 |
Issue: |
5 |
Pages: |
2913-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
MD2 activation by direct AGE interaction drives inflammatory diabetic cardiomyopathy. |
Volume: |
11 |
Issue: |
1 |
Pages: |
2148 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nie X |
Year: |
2012 |
Journal: |
Clin Immunol |
Title: |
Lipopolysaccharide mediated mast cells induce IL-10 producing regulatory T cells through the ICOSL/ICOS axis. |
Volume: |
142 |
Issue: |
3 |
Pages: |
269-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kono DH |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus. |
Volume: |
106 |
Issue: |
29 |
Pages: |
12061-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2014 |
Journal: |
Immunity |
Title: |
Activation of vascular endothelial growth factor receptor-3 in macrophages restrains TLR4-NF-κB signaling and protects against endotoxin shock. |
Volume: |
40 |
Issue: |
4 |
Pages: |
501-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ermolaeva MA |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. |
Volume: |
9 |
Issue: |
9 |
Pages: |
1037-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Z |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
Leukotriene B4 enhances the generation of proinflammatory microRNAs to promote MyD88-dependent macrophage activation. |
Volume: |
192 |
Issue: |
5 |
Pages: |
2349-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Geng Y |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
HMGB1-Neutralizing IgM Antibody Is a Normal Component of Blood Plasma. |
Volume: |
205 |
Issue: |
2 |
Pages: |
407-413 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheong C |
Year: |
2010 |
Journal: |
Cell |
Title: |
Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas. |
Volume: |
143 |
Issue: |
3 |
Pages: |
416-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang H |
Year: |
2018 |
Journal: |
Sci Transl Med |
Title: |
A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice. |
Volume: |
10 |
Issue: |
443 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Fordham JB |
Year: |
2012 |
Journal: |
Sci Rep |
Title: |
Environmental conditioning in the control of macrophage thrombospondin-1 production. |
Volume: |
2 |
|
Pages: |
512 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toda G |
Year: |
2020 |
Journal: |
Mol Cell |
Title: |
Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation. |
Volume: |
79 |
Issue: |
1 |
Pages: |
43-53.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Molle C |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process. |
Volume: |
184 |
Issue: |
4 |
Pages: |
1784-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rayees S |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
PAR2-Mediated cAMP Generation Suppresses TRPV4-Dependent Ca2+ Signaling in Alveolar Macrophages to Resolve TLR4-Induced Inflammation. |
Volume: |
27 |
Issue: |
3 |
Pages: |
793-805.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wynn JL |
Year: |
2008 |
Journal: |
Blood |
Title: |
Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. |
Volume: |
112 |
Issue: |
5 |
Pages: |
1750-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Willart MA |
Year: |
2012 |
Journal: |
J Exp Med |
Title: |
Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. |
Volume: |
209 |
Issue: |
8 |
Pages: |
1505-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yow SJ |
Year: |
2024 |
Journal: |
Cell Death Dis |
Title: |
Differential signalling requirements for RIPK1-dependent pyroptosis in neutrophils and macrophages. |
Volume: |
15 |
Issue: |
7 |
Pages: |
479 |
|
•
•
•
•
•
|
Publication |
First Author: |
González-Juarbe N |
Year: |
2017 |
Journal: |
Cell Death Differ |
Title: |
Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia. |
Volume: |
24 |
Issue: |
5 |
Pages: |
917-928 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen KW |
Year: |
2018 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion. |
Volume: |
200 |
Issue: |
10 |
Pages: |
3341-3346 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoshino K |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Critical role of IkappaB Kinase alpha in TLR7/9-induced type I IFN production by conventional dendritic cells. |
Volume: |
184 |
Issue: |
7 |
Pages: |
3341-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu H |
Year: |
2012 |
Journal: |
Nat Immunol |
Title: |
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. |
Volume: |
13 |
Issue: |
7 |
Pages: |
642-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee PP |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1576 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chu LH |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. |
Volume: |
9 |
Issue: |
1 |
Pages: |
996 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gradtke AC |
Year: |
2021 |
Journal: |
J Immunol |
Title: |
Deficiency of the Intramembrane Protease SPPL2a Alters Antimycobacterial Cytokine Responses of Dendritic Cells. |
Volume: |
206 |
Issue: |
1 |
Pages: |
164-180 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gottschalk RA |
Year: |
2019 |
Journal: |
Elife |
Title: |
IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses. |
Volume: |
8 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cuenca AG |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
TRIF-dependent innate immune activation is critical for survival to neonatal gram-negative sepsis. |
Volume: |
194 |
Issue: |
3 |
Pages: |
1169-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cucak H |
Year: |
2009 |
Journal: |
Immunity |
Title: |
Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells. |
Volume: |
31 |
Issue: |
3 |
Pages: |
491-501 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2022 |
Journal: |
Pharmacol Res |
Title: |
CD44 deficiency represses neuroinflammation and rescues dopaminergic neurons in a mouse model of Parkinson's disease. |
Volume: |
177 |
|
Pages: |
106133 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Donnell H |
Year: |
2014 |
Journal: |
Immunity |
Title: |
Toll-like receptor and inflammasome signals converge to amplify the innate bactericidal capacity of T helper 1 cells. |
Volume: |
40 |
Issue: |
2 |
Pages: |
213-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanayama M |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
The lung is protected from spontaneous inflammation by autophagy in myeloid cells. |
Volume: |
194 |
Issue: |
11 |
Pages: |
5465-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen F |
Year: |
2022 |
Journal: |
iScience |
Title: |
The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity. |
Volume: |
25 |
Issue: |
7 |
Pages: |
104561 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tong J |
Year: |
2021 |
Journal: |
Sci Adv |
Title: |
Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation. |
Volume: |
7 |
Issue: |
18 |
|
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•
•
•
•
•
|
Publication |
First Author: |
Li T |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
An endosomal LAPF is required for macrophage endocytosis and elimination of bacteria. |
Volume: |
116 |
Issue: |
26 |
Pages: |
12958-12963 |
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•
•
•
•
|
Publication |
First Author: |
Zhu CS |
Year: |
2023 |
Journal: |
Sci Adv |
Title: |
Identification of procathepsin L (pCTS-L)-neutralizing monoclonal antibodies to treat potentially lethal sepsis. |
Volume: |
9 |
Issue: |
5 |
Pages: |
eadf4313 |
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•
•
•
•
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Publication |
First Author: |
Lewitus GM |
Year: |
2016 |
Journal: |
Neuron |
Title: |
Microglial TNF-α Suppresses Cocaine-Induced Plasticity and Behavioral Sensitization. |
Volume: |
90 |
Issue: |
3 |
Pages: |
483-91 |
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•
•
•
•
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Publication |
First Author: |
Saijo K |
Year: |
2011 |
Journal: |
Cell |
Title: |
An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation. |
Volume: |
145 |
Issue: |
4 |
Pages: |
584-95 |
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•
•
•
•
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Publication |
First Author: |
Lee CY |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation. |
Volume: |
8 |
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Pages: |
15502 |
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•
•
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Publication |
First Author: |
Kleinridders A |
Year: |
2009 |
Journal: |
Cell Metab |
Title: |
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. |
Volume: |
10 |
Issue: |
4 |
Pages: |
249-59 |
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•
•
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Publication |
First Author: |
Sheikh BN |
Year: |
2020 |
Journal: |
Nat Cell Biol |
Title: |
Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. |
Volume: |
22 |
Issue: |
7 |
Pages: |
828-841 |
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•
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Publication |
First Author: |
Ziegler G |
Year: |
2007 |
Journal: |
Biochem Biophys Res Commun |
Title: |
TLR2 has a detrimental role in mouse transient focal cerebral ischemia. |
Volume: |
359 |
Issue: |
3 |
Pages: |
574-9 |
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•
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•
•
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Publication |
First Author: |
Banoth B |
Year: |
2015 |
Journal: |
Elife |
Title: |
Stimulus-selective crosstalk via the NF-κB signaling system reinforces innate immune response to alleviate gut infection. |
Volume: |
4 |
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•
•
•
•
•
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Publication |
First Author: |
Burguillos MA |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation. |
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•
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Publication |
First Author: |
Didierlaurent A |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide. |
Volume: |
26 |
Issue: |
3 |
Pages: |
735-42 |
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•
•
•
•
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Publication |
First Author: |
Layoun A |
Year: |
2012 |
Journal: |
Inflammation |
Title: |
Bacterial cell wall constituents induce hepcidin expression in macrophages through MyD88 signaling. |
Volume: |
35 |
Issue: |
4 |
Pages: |
1500-6 |
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•
•
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Publication |
First Author: |
Akira S |
Year: |
2000 |
Journal: |
J Endotoxin Res |
Title: |
The role of Toll-like receptors and MyD88 in innate immune responses. |
Volume: |
6 |
Issue: |
5 |
Pages: |
383-7 |
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•
•
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Publication |
First Author: |
Stanley AC |
Year: |
2012 |
Journal: |
J Leukoc Biol |
Title: |
Recycling endosome-dependent and -independent mechanisms for IL-10 secretion in LPS-activated macrophages. |
Volume: |
92 |
Issue: |
6 |
Pages: |
1227-39 |
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•
•
•
•
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Publication |
First Author: |
Buckley JM |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Increased susceptibility of ST2-deficient mice to polymicrobial sepsis is associated with an impaired bactericidal function. |
Volume: |
187 |
Issue: |
8 |
Pages: |
4293-9 |
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•
•
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Publication |
First Author: |
Allen JL |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Cutting edge: regulation of TLR4-driven B cell proliferation by RP105 is not B cell autonomous. |
Volume: |
188 |
Issue: |
5 |
Pages: |
2065-9 |
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•
•
•
|
Publication |
First Author: |
Lu H |
Year: |
2022 |
Journal: |
Cell Host Microbe |
Title: |
Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis. |
Volume: |
30 |
Issue: |
8 |
Pages: |
1139-1150.e7 |
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•
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Publication |
First Author: |
Zhang J |
Year: |
2022 |
Journal: |
iScience |
Title: |
Na/K-ATPase suppresses LPS-induced pro-inflammatory signaling through Lyn. |
Volume: |
25 |
Issue: |
9 |
Pages: |
104963 |
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Publication |
First Author: |
Lehner MD |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. |
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166 |
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8 |
Pages: |
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Publication |
First Author: |
Müller P |
Year: |
2010 |
Journal: |
Infect Immun |
Title: |
The Staphylococcus aureus lipoprotein SitC colocalizes with Toll-like receptor 2 (TLR2) in murine keratinocytes and elicits intracellular TLR2 accumulation. |
Volume: |
78 |
Issue: |
10 |
Pages: |
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Publication |
First Author: |
Zhao XJ |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
TRIF and IRF-3 binding to the TNF promoter results in macrophage TNF dysregulation and steatosis induced by chronic ethanol. |
Volume: |
181 |
Issue: |
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Pages: |
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Publication |
First Author: |
Chattopadhyay S |
Year: |
2013 |
Journal: |
MBio |
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Inhibition of viral pathogenesis and promotion of the septic shock response to bacterial infection by IRF-3 are regulated by the acetylation and phosphorylation of its coactivators. |
Volume: |
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2 |
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First Author: |
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Year: |
2016 |
Journal: |
Cell Death Differ |
Title: |
Ly6C(+) monocyte efferocytosis and cross-presentation of cell-associated antigens. |
Volume: |
23 |
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Year: |
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Journal: |
Nat Commun |
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Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation. |
Volume: |
10 |
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Pore D |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Ezrin Regulates Inflammation by Limiting B Cell IL-10 Production. |
Volume: |
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Year: |
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Journal: |
Cell Rep |
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IL-6-induced FOXO1 activity determines the dynamics of metabolism in CD8 T cells cross-primed by liver sinusoidal endothelial cells. |
Volume: |
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First Author: |
Selvanantham T |
Year: |
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Journal: |
J Immunol |
Title: |
Nod1 and Nod2 enhance TLR-mediated invariant NKT cell activation during bacterial infection. |
Volume: |
191 |
Issue: |
11 |
Pages: |
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Publication |
First Author: |
Sakaguchi S |
Year: |
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Journal: |
Biochem Biophys Res Commun |
Title: |
Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock. |
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Publication |
First Author: |
Medgyesi D |
Year: |
2014 |
Journal: |
J Exp Med |
Title: |
The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity. |
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First Author: |
Zong J |
Year: |
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Journal: |
Lab Invest |
Title: |
NOD2 deletion promotes cardiac hypertrophy and fibrosis induced by pressure overload. |
Volume: |
93 |
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Publication |
First Author: |
Fairfax KA |
Year: |
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Journal: |
J Leukoc Biol |
Title: |
IL-10 regulates Aicda expression through miR-155. |
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97 |
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Publication |
First Author: |
John SP |
Year: |
2018 |
Journal: |
Cell Rep |
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IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages. |
Volume: |
25 |
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1 |
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95-106.e6 |
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