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Search results 401 to 500 out of 2088 for Lck

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1843823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_09
Specimen Label: euxassay_002601_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1843823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_10
Specimen Label: euxassay_002601_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1843823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_18
Specimen Label: euxassay_002601_18
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540568
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2024-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7621973
Age: embryonic day 14.5
Image: S5Cf
Specimen Label: S5Cf
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1822623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_10
Specimen Label: euxassay_002601_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1822623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_17
Specimen Label: euxassay_002601_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_09
Specimen Label: euxassay_002601_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_10
Specimen Label: euxassay_002601_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_11
Specimen Label: euxassay_002601_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_17
Specimen Label: euxassay_002601_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_18
Specimen Label: euxassay_002601_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_04
Specimen Label: euxassay_002601_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_05
Specimen Label: euxassay_002601_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_06
Specimen Label: euxassay_002601_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_07
Specimen Label: euxassay_002601_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_08
Specimen Label: euxassay_002601_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_09
Specimen Label: euxassay_002601_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_18
Specimen Label: euxassay_002601_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_19
Specimen Label: euxassay_002601_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_20
Specimen Label: euxassay_002601_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_21
Specimen Label: euxassay_002601_21
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_22
Specimen Label: euxassay_002601_22
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_10
Specimen Label: euxassay_002601_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_11
Specimen Label: euxassay_002601_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_12
Specimen Label: euxassay_002601_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_13
Specimen Label: euxassay_002601_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_14
Specimen Label: euxassay_002601_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_15
Specimen Label: euxassay_002601_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_16
Specimen Label: euxassay_002601_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_01
Specimen Label: euxassay_002601_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_02
Specimen Label: euxassay_002601_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_03
Specimen Label: euxassay_002601_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_04
Specimen Label: euxassay_002601_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_05
Specimen Label: euxassay_002601_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_06
Specimen Label: euxassay_002601_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_07
Specimen Label: euxassay_002601_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_08
Specimen Label: euxassay_002601_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_09
Specimen Label: euxassay_002601_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_10
Specimen Label: euxassay_002601_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_11
Specimen Label: euxassay_002601_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_12
Specimen Label: euxassay_002601_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_13
Specimen Label: euxassay_002601_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_14
Specimen Label: euxassay_002601_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_15
Specimen Label: euxassay_002601_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_16
Specimen Label: euxassay_002601_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_17
Specimen Label: euxassay_002601_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_18
Specimen Label: euxassay_002601_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_19
Specimen Label: euxassay_002601_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_20
Specimen Label: euxassay_002601_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_21
Specimen Label: euxassay_002601_21
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_22
Specimen Label: euxassay_002601_22
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:1817720
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825927
Age: embryonic day 14.5
Image: euxassay_002601_23
Specimen Label: euxassay_002601_23
Detected: true
Specimen Num: 23
Publication
First Author: Lindquist S
Year: 2011
Journal: PLoS One
Title: Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation.
Volume: 6
Issue: 9
Pages: e23978
Publication
First Author: McNeill L
Year: 2007
Journal: Immunity
Title: The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.
Volume: 27
Issue: 3
Pages: 425-37
Strain
Attribute String: targeted mutation, mutant strain, congenic
Allele
Name: Lck interacting transmembrane adaptor 1; endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Genotype
Symbol: Lime1/Lime1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Interaction Experiment
Description: The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl.
Publication
First Author: Shimizu C
Year: 2001
Journal: Int Immunol
Title: Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity.
Volume: 13
Issue: 1
Pages: 105-17
Publication
First Author: Fehling HJ
Year: 1997
Journal: Immunity
Title: Restoration of thymopoiesis in pT alpha-/- mice by anti-CD3epsilon antibody treatment or with transgenes encoding activated Lck or tailless pT alpha.
Volume: 6
Issue: 6
Pages: 703-14
Publication
First Author: Shenoy-Scaria AM
Year: 1993
Journal: Mol Cell Biol
Title: Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins.
Volume: 13
Issue: 10
Pages: 6385-92
Publication  
First Author: Koegl M
Year: 1994
Journal: Biochem J
Title: Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif.
Volume: 303 ( Pt 3)
Pages: 749-53
Publication
First Author: Li M
Year: 2008
Journal: Mol Cell Biol
Title: The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.
Volume: 28
Issue: 2
Pages: 630-41
Publication
First Author: Grégoire C
Year: 2007
Journal: Eur J Immunol
Title: Deletion of the LIME adaptor protein minimally affects T and B cell development and function.
Volume: 37
Issue: 11
Pages: 3259-69
GO Term
Strain
Attribute String: coisogenic
Genotype
Symbol: Lime1/Lime1
Background: C57BL/6NCrl-Lime1/Ieg
Zygosity: hm
Has Mutant Allele: true
Interaction Experiment
Description: Direct interaction of the CD38 cytoplasmic tail and the Lck SH2 domain. Cd38 transduces T cell activation signals through associated Lck.
Publication
First Author: Fiala GJ
Year: 2019
Journal: J Immunol
Title: Proximal Lck Promoter-Driven Cre Function Is Limited in Neonatal and Ineffective in Adult γδ T Cell Development.
Volume: 203
Issue: 2
Pages: 569-579
Publication
First Author: Palacios EH
Year: 2004
Journal: Oncogene
Title: Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation.
Volume: 23
Issue: 48
Pages: 7990-8000
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Genotype
Symbol: Lime1/Lime1 Rag2/Rag2 Tg(TcraH-Y,TcrbH-Y)1Pas/?
Background: B6.Cg-Rag2 Lime1 Tg(TcraH-Y,TcrbH-Y)1Pas
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Lat2/Lat2 Lime1/Lime1
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Lime1/Lime1 Pag1/Pag1
Background: involves: 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Giglione C
Year: 2001
Journal: Eur J Biochem
Title: Differential actions of p60c-Src and Lck kinases on the Ras regulators p120-GAP and GDP/GTP exchange factor CDC25Mm.
Volume: 268
Issue: 11
Pages: 3275-83
Allele
Name: transgene insertion 1, Hiroaki Honda
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
Allele
Name: lymphocyte protein tyrosine kinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: transgene insertion 1, Shunsuke Ishii
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 1, Junji Takeda
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion P1, Toshinori Nakayama
Allele Type: Transgenic
Attribute String: Inserted expressed sequence