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Search results 601 to 669 out of 669 for Tsc2

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Type Details Score
Publication
21403402 | J:172004
First Author: Feliciano DM
Year: 2011
Journal: J Clin Invest
Title: Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice.
Volume: 121
Issue: 4
Pages: 1596-607
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Publication
15781664 | J:97168
First Author: El-Hashemite N
Year: 2005
Journal: Cancer Res
Title: Estrogen enhances whereas tamoxifen retards development of Tsc mouse liver hemangioma: a tumor related to renal angiomyolipoma and pulmonary lymphangioleiomyomatosis.
Volume: 65
Issue: 6
Pages: 2474-81
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Publication
18495876 | J:136366
First Author: Meikle L
Year: 2008
Journal: J Neurosci
Title: Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function.
Volume: 28
Issue: 21
Pages: 5422-32
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Publication
19966866 | J:160400
First Author: Liang MC
Year: 2010
Journal: Oncogene
Title: TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.
Volume: 29
Issue: 11
Pages: 1588-97
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Publication
24633152 | J:215111
First Author: Pilipow K
Year: 2014
Journal: PLoS One
Title: Monoallelic germline TSC1 mutations are permissive for T lymphocyte development and homeostasis in tuberous sclerosis complex individuals.
Volume: 9
Issue: 3
Pages: e91952
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Publication
33536341 | J:301986
 
First Author: Barone S
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Kidney intercalated cells and the transcription factor FOXi1 drive cystogenesis in tuberous sclerosis complex.
Volume: 118
Issue: 6
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Publication
23851502 | J:212578
First Author: Guo Y
Year: 2014
Journal: Oncogene
Title: Tsc1-Tp53 loss induces mesothelioma in mice, and evidence for this mechanism in human mesothelioma.
Volume: 33
Issue: 24
Pages: 3151-60
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Publication
15601645 | J:96138
First Author: Meikle L
Year: 2005
Journal: Hum Mol Genet
Title: A mouse model of cardiac rhabdomyoma generated by loss of Tsc1 in ventricular myocytes.
Volume: 14
Issue: 3
Pages: 429-35
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Publication
21212099 | J:169239
First Author: Malhowski AJ
Year: 2011
Journal: Hum Mol Genet
Title: Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Volume: 20
Issue: 7
Pages: 1290-305
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Publication
26449264 | J:226834
First Author: Jones I
Year: 2015
Journal: Dis Model Mech
Title: A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development.
Volume: 8
Issue: 12
Pages: 1517-29
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Publication
30760873 | J:305028
First Author: Li C
Year: 2019
Journal: Cell Death Differ
Title: mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis.
Volume: 26
Issue: 10
Pages: 2015-2028
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Publication
19690069 | J:159576
First Author: Mori H
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Critical roles for the TSC-mTOR pathway in β-cell function.
Volume: 297
Issue: 5
Pages: E1013-22
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Publication
33071758 | J:313985
 
First Author: Wundrach D
Year: 2020
Journal: Front Mol Neurosci
Title: A Human TSC1 Variant Screening Platform in Gabaergic Cortical Interneurons for Genotype to Phenotype Assessments.
Volume: 13
Pages: 573409
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Publication
26037201 | J:225916
First Author: Xu G
Year: 2015
Journal: Diabetologia
Title: Intestinal mTOR regulates GLP-1 production in mouse L cells.
Volume: 58
Issue: 8
Pages: 1887-97
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Publication
26296882 | J:225965
First Author: Hu Z
Year: 2015
Journal: J Biol Chem
Title: Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis.
Volume: 290
Issue: 42
Pages: 25756-65
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Publication
24599401 | J:210659
First Author: Di Nardo A
Year: 2014
Journal: Hum Mol Genet
Title: Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.
Volume: 23
Issue: 14
Pages: 3865-74
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Publication
19420259 | J:148479
First Author: Di Nardo A
Year: 2009
Journal: J Neurosci
Title: Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner.
Volume: 29
Issue: 18
Pages: 5926-37
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Publication
22674026 | J:188431
First Author: Armour EA
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.
Volume: 303
Issue: 4
Pages: F584-92
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Publication
19692352 | J:153717
First Author: Zhou J
Year: 2009
Journal: Hum Mol Genet
Title: Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1.
Volume: 18
Issue: 22
Pages: 4428-41
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Publication
23696872 | J:221022
First Author: Prabhakar S
Year: 2013
Journal: PLoS One
Title: Stochastic model of Tsc1 lesions in mouse brain.
Volume: 8
Issue: 5
Pages: e64224
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Publication
16912167 | J:112107
First Author: Wilson C
Year: 2006
Journal: Cancer Res
Title: Tsc1 haploinsufficiency without mammalian target of rapamycin activation is sufficient for renal cyst formation in Tsc1+/- mice.
Volume: 66
Issue: 16
Pages: 7934-8
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Publication
23049074 | J:191137
First Author: Carson RP
Year: 2013
Journal: Hum Mol Genet
Title: Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.
Volume: 22
Issue: 1
Pages: 140-52
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Publication
31599935 | J:281732
First Author: Jin X
Year: 2019
Journal: Endocrinology
Title: Cartilage Ablation of Sirt1 Causes Inhibition of Growth Plate Chondrogenesis by Hyperactivation of mTORC1 Signaling.
Volume: 160
Issue: 12
Pages: 3001-3017
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Publication
23197407 | J:232309
First Author: Wang RH
Year: 2013
Journal: EMBO Mol Med
Title: The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling.
Volume: 5
Issue: 1
Pages: 137-48
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Publication
28933629 | J:337049
First Author: Kim SH
Year: 2017
Journal: Autophagy
Title: Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition.
Volume: 13
Issue: 10
Pages: 1767-1781
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Publication
15888477 | J:99796
First Author: Wilson C
Year: 2005
Journal: Hum Mol Genet
Title: A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma.
Volume: 14
Issue: 13
Pages: 1839-50
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Publication
23901139 | J:259996
First Author: Ersoy BA
Year: 2013
Journal: Sci Signal
Title: Phosphatidylcholine transfer protein interacts with thioesterase superfamily member 2 to attenuate insulin signaling.
Volume: 6
Issue: 286
Pages: ra64
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Publication
9721882 | J:49218
First Author: Chung DC
Year: 1998
Journal: Cancer Res
Title: Localization of putative tumor suppressor loci by genome-wide allelotyping in human pancreatic endocrine tumors.
Volume: 58
Issue: 16
Pages: 3706-11
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Publication
9861021 | J:51662
First Author: Rennebeck G
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Loss of function of the tuberous sclerosis 2 tumor suppressor gene results in embryonic lethality characterized by disrupted neuroepithelial growth and development.
Volume: 95
Issue: 26
Pages: 15629-34
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Publication
10029074 | J:52822
First Author: Satake N
Year: 1999
Journal: Cancer Res
Title: Isolation and characterization of a rat homologue of the human tuberous sclerosis 1 gene (Tsc1) and analysis of its mutations in rat renal carcinomas.
Volume: 59
Issue: 4
Pages: 849-55
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Publication
15150095 | J:90253
First Author: El-Hashemite N
Year: 2004
Journal: Cancer Res
Title: Perturbed IFN-gamma-Jak-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-gamma treatment.
Volume: 64
Issue: 10
Pages: 3436-43
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Publication
12547704 | J:94888
First Author: Cai S
Year: 2003
Journal: Am J Pathol
Title: Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development.
Volume: 162
Issue: 2
Pages: 457-68
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Publication
17290308 | J:120746
First Author: Zhang H
Year: 2007
Journal: J Clin Invest
Title: PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR.
Volume: 117
Issue: 3
Pages: 730-8
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Publication
18490760 | J:136345
First Author: Dan HC
Year: 2008
Journal: J Immunol
Title: Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt.
Volume: 180
Issue: 11
Pages: 7582-9
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Publication
20363874 | J:162261
First Author: Ning J
Year: 2010
Journal: Mol Endocrinol
Title: AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation.
Volume: 24
Issue: 6
Pages: 1218-29
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Publication
20068142 | J:164333
First Author: Chakrabarti P
Year: 2010
Journal: Diabetes
Title: Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage.
Volume: 59
Issue: 4
Pages: 775-81
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Publication
23354068 | J:199039
First Author: Zhang B
Year: 2013
Journal: Biochim Biophys Acta
Title: Mitochondrial aldehyde dehydrogenase obliterates endoplasmic reticulum stress-induced cardiac contractile dysfunction via correction of autophagy.
Volume: 1832
Issue: 4
Pages: 574-84
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Publication
24691995 | J:210808
First Author: Tyryshkin A
Year: 2014
Journal: Cancer Res
Title: SRC kinase is a novel therapeutic target in lymphangioleiomyomatosis.
Volume: 74
Issue: 7
Pages: 1996-2005
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Publication
24604753 | J:210827
First Author: Ferrer I
Year: 2014
Journal: J Pathol
Title: Tubers from patients with tuberous sclerosis complex are characterized by changes in microtubule biology through ROCK2 signalling.
Volume: 233
Issue: 3
Pages: 247-57
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Publication
29339522 | J:257758
First Author: Le K
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Effect of beta-agonists on LAM progression and treatment.
Volume: 115
Issue: 5
Pages: E944-E953
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Publication
25372051 | J:259834
First Author: Mackey AM
Year: 2014
Journal: Sci Signal
Title: PIP4kγ is a substrate for mTORC1 that maintains basal mTORC1 signaling during starvation.
Volume: 7
Issue: 350
Pages: ra104
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Publication
29406787 | J:275730
First Author: Steagall WK
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: The Lymphangioleiomyomatosis Lung Cell and Its Human Cell Models.
Volume: 58
Issue: 6
Pages: 678-683
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Publication
32078336 | J:306071
First Author: Han F
Year: 2020
Journal: Am J Respir Cell Mol Biol
Title: Adoptive T-Cell Transfer to Treat Lymphangioleiomyomatosis.
Volume: 62
Issue: 6
Pages: 793-804
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Publication
34301883 | J:308543
 
First Author: Lai M
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Tsc1 regulates tight junction independent of mTORC1.
Volume: 118
Issue: 30
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Publication
34544857 | J:311176
 
First Author: Wang J
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells.
Volume: 118
Issue: 39
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Publication
35931213 | J:330809
 
First Author: Koike-Kumagai M
Year: 2022
Journal: Neuropharmacology
Title: Sirolimus relieves seizures and neuropsychiatric symptoms via changes of microglial polarity in tuberous sclerosis complex model mice.
Volume: 218
Pages: 109203
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Protein
Q61037
Organism: Mus musculus/domesticus
Length: 1814  
Fragment?: false
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Protein
Q3UHB2
Organism: Mus musculus/domesticus
Length: 1808  
Fragment?: false
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Protein
A0A2I3BRT5
Organism: Mus musculus/domesticus
Length: 1741  
Fragment?: false
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Protein
A0A2I3BPP1
Organism: Mus musculus/domesticus
Length: 1785  
Fragment?: false
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Protein
Q3TCQ7
Organism: Mus musculus/domesticus
Length: 1742  
Fragment?: false
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Protein
Q3UG88
Organism: Mus musculus/domesticus
Length: 1785  
Fragment?: false
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Protein
Q3UGI8
Organism: Mus musculus/domesticus
Length: 1678  
Fragment?: true
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Protein
Q7TT21
Organism: Mus musculus/domesticus
Length: 1742  
Fragment?: false
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Publication
29023667 | J:273722
First Author: Zou J
Year: 2017
Journal: Epilepsia
Title: Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner.
Volume: 58
Issue: 12
Pages: 2053-2063
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Publication
28694334 | J:246657
First Author: McLane LE
Year: 2017
Journal: J Neurosci
Title: Loss of Tuberous Sclerosis Complex1 in Adult Oligodendrocyte Progenitor Cells Enhances Axon Remyelination and Increases Myelin Thickness after a Focal Demyelination.
Volume: 37
Issue: 31
Pages: 7534-7546
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Publication
26224859 | J:226921
First Author: Nie D
Year: 2015
Journal: J Neurosci
Title: The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex.
Volume: 35
Issue: 30
Pages: 10762-72
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Publication
32375878 | J:317669
First Author: Haji N
Year: 2020
Journal: Mol Autism
Title: Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
Volume: 11
Issue: 1
Pages: 29
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Publication
30467464 | J:312062
 
First Author: Cox RL
Year: 2018
Journal: Front Mol Neurosci
Title: Multiple Critical Periods for Rapamycin Treatment to Correct Structural Defects in Tsc-1-Suppressed Brain.
Volume: 11
Pages: 409
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Publication
28701918 | J:314369
 
First Author: Lee Y
Year: 2017
Journal: Front Mol Neurosci
Title: Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling.
Volume: 10
Pages: 201
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Publication
20041218 | J:161738
First Author: Mashimo T
Year: 2009
Journal: PLoS Genet
Title: Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase.
Volume: 5
Issue: 12
Pages: e1000784
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Publication
28347844 | J:255686
First Author: Zhang Y
Year: 2017
Journal: Biochim Biophys Acta
Title: Complex inhibition of autophagy by mitochondrial aldehyde dehydrogenase shortens lifespan and exacerbates cardiac aging.
Volume: 1863
Issue: 8
Pages: 1919-1932
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Publication
38028758 | J:343064
 
First Author: Soleimani M
Year: 2023
Journal: Front Physiol
Title: Not all kidney cysts are created equal: a distinct renal cystogenic mechanism in tuberous sclerosis complex (TSC).
Volume: 14
Pages: 1289388
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Publication
31744486 | J:287187
First Author: Liu W
Year: 2019
Journal: BMC Complement Altern Med
Title: Weipiling ameliorates gastric precancerous lesions in Atp4a-/- mice.
Volume: 19
Issue: 1
Pages: 318
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Protein
Q8BNK4
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: true
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Protein
Q921J2
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Protein
Q9ESR1
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Protein
Q540E6
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Protein
E9PZP8
Organism: Mus musculus/domesticus
Length: 4859  
Fragment?: false
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