Type |
Details |
Score |
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Visel A |
Year: |
2004 |
Journal: |
Nucleic Acids Res |
Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
Volume: |
32 |
Issue: |
Database issue |
Pages: |
D552-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Picard C |
Year: |
2013 |
Journal: |
Arthritis Rheum |
Title: |
Nuclear accumulation of prohibitin 1 in osteoarthritic chondrocytes down-regulates PITX1 expression. |
Volume: |
65 |
Issue: |
4 |
Pages: |
993-1003 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE27363 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5494439 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1638417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5494562 |
Age: |
embryonic day 10.5 |
Image: |
2B |
Note: |
Expression overlaps with that of Pitx1 and Pitx2. |
Specimen Label: |
2B |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5494439 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1638215 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:5494562 |
Age: |
embryonic day 9.5 |
Image: |
2A |
Note: |
Expression overlaps with that of Pitx1 and Pitx2. |
Specimen Label: |
2A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5494437 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1638215 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:5494442 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression is exclusive with Pitx1 and Pitx2 expression. |
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
Baseline and WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5494437 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1638417 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:5494442 |
Age: |
embryonic day 10.5 |
Image: |
3C |
Note: |
Expressed in specific epithelium region, exclusive with Pitx1 and Pitx2 expression. |
Specimen Label: |
3C |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Allele |
Name: |
paired-like homeodomain transcription factor 1; endonuclease-mediated mutation 1, Guillaume Andrey |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
315
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeyabalan J |
Year: |
2010 |
Journal: |
PLoS One |
Title: |
SEDLIN forms homodimers: characterisation of SEDLIN mutations and their interactions with transcription factors MBP1, PITX1 and SF1. |
Volume: |
5 |
Issue: |
5 |
Pages: |
e10646 |
|
•
•
•
•
•
|
Allele |
Name: |
collagen, type I, alpha 1; targeted mutation 1, Stefan Mundlos |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 493; endonuclease-mediated mutation 1, Guillaume Andrey |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 492; endonuclease-mediated mutation 1, Guillaume Andrey |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
Allele |
Name: |
inversion, Chr 13, Guillaume Andrey 1 |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
Allele |
Name: |
inversion, Chr 13, Guillaume Andrey 2 |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 493; endonuclease-mediated mutation 3, Guillaume Andrey |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pitx1/Pitx1 |
Background: |
involves: 129S6/SvEvTac * C57BL/6NCrl |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5749202 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-02-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3599824 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:5749787 |
Age: |
embryonic day 16.5 |
|
Note: |
Immunopositive corticotrophs were found that co-expressed Pitx1 at both high and low levels. Those immunopositive corticotrophs that co-expressed high levels of Pitx1 were mostly found in the ventral region of the gland. |
Specimen Label: |
4K |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5749202 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-02-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3599824 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:5749787 |
Age: |
embryonic day 16.5 |
|
Note: |
Immunopositive corticotrophs were found that co-expressed Pitx1 at both high and low levels. Those immunopositive corticotrophs that co-expressed high levels of Pitx1 were mostly found in the ventral region of the gland. |
Specimen Label: |
4L |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Allele |
Name: |
deletion, Chr 13, Guillaume Andrey 1 |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region, Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
deletion, Chr 13, Guillaume Andrey 2 |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region, Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 493; endonuclease-mediated mutation 2, Guillaume Andrey |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 496; endonuclease-mediated mutation 1, Guillaume Andrey |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 492; endonuclease-mediated mutation 2, Guillaume Andrey |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 496; endonuclease-mediated mutation 2, Guillaume Andrey |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Col1a1/Col1a1<+> |
Background: |
involves: 129S4/SvJae * C57BL/6 |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
collagen, type I, alpha 1; targeted mutation 1, Guillaume Andrey |
Allele Type: |
Targeted |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
collagen, type I, alpha 1; targeted mutation 4, Guillaume Andrey |
Allele Type: |
Targeted |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rr496/Rr496<+> |
Background: |
involves: 129S6/SvEvTac * C57BL/6NCrl |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rr493/Rr493 |
Background: |
involves: 129S6/SvEvTac * C57BL/6NCrl |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 492; endonuclease-mediated mutation 1.1, James Noonan |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Hypomorph |
|
•
•
•
•
•
|
Allele |
Name: |
collagen, type I, alpha 1; targeted mutation 2, Guillaume Andrey |
Allele Type: |
Targeted |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
collagen, type I, alpha 1; targeted mutation 3, Guillaume Andrey |
Allele Type: |
Targeted |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
collagen, type I, alpha 1; targeted mutation 5, Guillaume Andrey |
Allele Type: |
Targeted |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
collagen, type I, alpha 1; targeted mutation 6, Guillaume Andrey |
Allele Type: |
Targeted |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Strain |
Attribute String: |
endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rr492/Rr492 |
Background: |
involves: C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rr493/Rr493<+> Rr496/Rr496<+> |
Background: |
involves: 129S6/SvEvTac * C57BL/6NCrl |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE2560 |
Experiment Type: |
transcription profiling by array |
Study Type: |
Baseline |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin CR |
Year: |
1999 |
Journal: |
Nature |
Title: |
Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. |
Volume: |
401 |
Issue: |
6750 |
Pages: |
279-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coulon V |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
A muscle-specific promoter directs Pitx3 gene expression in skeletal muscle cells. |
Volume: |
282 |
Issue: |
45 |
Pages: |
33192-200 |
|
•
•
•
•
•
|
Publication |
First Author: |
Langlais D |
Year: |
2011 |
Journal: |
Mol Endocrinol |
Title: |
A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells. |
Volume: |
25 |
Issue: |
2 |
Pages: |
348-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quirk J |
Year: |
2002 |
Journal: |
J Mol Endocrinol |
Title: |
Hesx1 homeodomain protein represses transcription as a monomer and antagonises transactivation of specific sites as a homodimer. |
Volume: |
28 |
Issue: |
3 |
Pages: |
193-205 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarra DV |
Year: |
2013 |
Journal: |
Mol Endocrinol |
Title: |
Forkhead box O1 is a repressor of basal and GnRH-induced Fshb transcription in gonadotropes. |
Volume: |
27 |
Issue: |
11 |
Pages: |
1825-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mutant Mouse Regional Resource Centers |
Year: |
2004 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) |
|
|
|
|
•
•
•
•
•
|