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Search results 1 to 100 out of 130 for Chek1

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Category: Publication
Type Details Score
Publication
First Author: Abe H
Year: 2018
Journal: Hum Mol Genet
Title: CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice.
Volume: 27
Issue: 7
Pages: 1136-1149
Publication
First Author: Li F
Year: 2021
Journal: Nat Commun
Title: The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation.
Volume: 12
Issue: 1
Pages: 3845
Publication  
First Author: Muralidharan SV
Year: 2020
Journal: Life Sci Alliance
Title: Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells.
Volume: 3
Issue: 8
Publication
First Author: Sanchez Y
Year: 1997
Journal: Science
Title: Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.
Volume: 277
Issue: 5331
Pages: 1497-501
Publication
First Author: Takai H
Year: 2000
Journal: Genes Dev
Title: Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice.
Volume: 14
Issue: 12
Pages: 1439-47
Publication
First Author: Lam MH
Year: 2004
Journal: Cancer Cell
Title: Chk1 is haploinsufficient for multiple functions critical to tumor suppression.
Volume: 6
Issue: 1
Pages: 45-59
Publication
First Author: Shimada M
Year: 2008
Journal: Cell
Title: Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression.
Volume: 132
Issue: 2
Pages: 221-32
Publication
First Author: Smith J
Year: 2013
Journal: Pigment Cell Melanoma Res
Title: Chk1 is essential for the development of murine epidermal melanocytes.
Volume: 26
Issue: 4
Pages: 580-5
Publication
First Author: Peddibhotla S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis.
Volume: 106
Issue: 13
Pages: 5159-64
Publication
First Author: Tho LM
Year: 2012
Journal: Oncogene
Title: Chk1 is essential for chemical carcinogen-induced mouse skin tumorigenesis.
Volume: 31
Issue: 11
Pages: 1366-75
Publication
First Author: Chen P
Year: 2000
Journal: Cell
Title: The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation.
Volume: 100
Issue: 6
Pages: 681-92
Publication
First Author: Haruki N
Year: 2000
Journal: Cancer Res
Title: Histological type-selective, tumor-predominant expression of a novel CHK1 isoform and infrequent in vivo somatic CHK2 mutation in small cell lung cancer.
Volume: 60
Issue: 17
Pages: 4689-92
Publication
First Author: Smits VA
Year: 2006
Journal: Curr Biol
Title: Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.
Volume: 16
Issue: 2
Pages: 150-9
Publication
First Author: Niida H
Year: 2007
Journal: Mol Cell Biol
Title: Specific role of Chk1 phosphorylations in cell survival and checkpoint activation.
Volume: 27
Issue: 7
Pages: 2572-81
Publication
First Author: Malzer E
Year: 2010
Journal: J Cell Sci
Title: Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response.
Volume: 123
Issue: Pt 17
Pages: 2892-900
Publication
First Author: Matsuyama M
Year: 2011
Journal: J Cell Sci
Title: Nuclear Chk1 prevents premature mitotic entry.
Volume: 124
Issue: Pt 13
Pages: 2113-9
Publication
First Author: Zineldeen DH
Year: 2017
Journal: Med Oncol
Title: Alternative Chk1-independent S/M checkpoint in somatic cells that prevents premature mitotic entry.
Volume: 34
Issue: 4
Pages: 70
Publication
First Author: Bernard JJ
Year: 2014
Journal: Exp Mol Pathol
Title: Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice.
Volume: 96
Issue: 1
Pages: 126-31
Publication
First Author: Schoeler K
Year: 2019
Journal: Cell Death Differ
Title: CHK1 dosage in germinal center B cells controls humoral immunity.
Volume: 26
Issue: 12
Pages: 2551-2567
Publication
First Author: Schuler F
Year: 2017
Journal: Nat Commun
Title: Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis.
Volume: 8
Issue: 1
Pages: 1697
Publication
First Author: Naruyama H
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Essential role of Chk1 in S phase progression through regulation of RNR2 expression.
Volume: 374
Issue: 1
Pages: 79-83
Publication
First Author: Jiang K
Year: 2003
Journal: J Biol Chem
Title: Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345.
Volume: 278
Issue: 27
Pages: 25207-17
Publication
First Author: Flaggs G
Year: 1997
Journal: Curr Biol
Title: Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes.
Volume: 7
Issue: 12
Pages: 977-86
Publication
First Author: Lunardi A
Year: 2015
Journal: Cancer Discov
Title: Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis.
Volume: 5
Issue: 5
Pages: 550-63
Publication
First Author: Greenow KR
Year: 2014
Journal: Oncogene
Title: Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency.
Volume: 33
Issue: 31
Pages: 4089-96
Publication
First Author: Greenow KR
Year: 2009
Journal: Oncogene
Title: Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation.
Volume: 28
Issue: 11
Pages: 1443-53
Publication
First Author: Schuler F
Year: 2019
Journal: EMBO Rep
Title: Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.
Volume: 20
Issue: 8
Pages: e47026
Publication
First Author: Fishler T
Year: 2010
Journal: Oncogene
Title: Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53.
Volume: 29
Issue: 28
Pages: 4007-17
Publication
First Author: Ruth KS
Year: 2021
Journal: Nature
Title: Genetic insights into biological mechanisms governing human ovarian ageing.
Volume: 596
Issue: 7872
Pages: 393-397
Publication
First Author: Niida H
Year: 2010
Journal: EMBO J
Title: Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo.
Volume: 29
Issue: 20
Pages: 3558-70
Publication
First Author: Zhang Y
Year: 2006
Journal: J Neurosci
Title: The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin.
Volume: 26
Issue: 34
Pages: 8819-28
Publication
First Author: Zaugg K
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.
Volume: 104
Issue: 10
Pages: 3805-10
Publication
First Author: Ullah Z
Year: 2011
Journal: Mol Cell Biol
Title: Checkpoint kinase 1 prevents cell cycle exit linked to terminal cell differentiation.
Volume: 31
Issue: 19
Pages: 4129-43
Publication  
First Author: Shentu Y
Year: 2024
Journal: Exp Neurol
Title: Hydrogen sulfide ameliorates lipopolysaccharide-induced anxiety-like behavior by inhibiting checkpoint kinase 1 activation in the hippocampus of mice.
Volume: 371
Pages: 114586
Publication
First Author: Amable L
Year: 2011
Journal: J Biol Chem
Title: Disruption of serine/threonine protein phosphatase 5 (PP5:PPP5c) in mice reveals a novel role for PP5 in the regulation of ultraviolet light-induced phosphorylation of serine/threonine protein kinase Chk1 (CHEK1).
Volume: 286
Issue: 47
Pages: 40413-22
Publication  
First Author: Her J
Year: 2018
Journal: Mol Cell Biol
Title: 53BP1 Mediates ATR-Chk1 Signaling and Protects Replication Forks under Conditions of Replication Stress.
Volume: 38
Issue: 8
Publication
First Author: Chen CH
Year: 2012
Journal: PLoS One
Title: Disruption of murine mp29/Syf2/Ntc31 gene results in embryonic lethality with aberrant checkpoint response.
Volume: 7
Issue: 3
Pages: e33538
Publication
First Author: Grote D
Year: 2015
Journal: Cell Rep
Title: E4F1 is a master regulator of CHK1-mediated functions.
Volume: 11
Issue: 2
Pages: 210-9
Publication
First Author: Leonard JM
Year: 2008
Journal: J Cell Biol
Title: Sonic Hedgehog signaling impairs ionizing radiation-induced checkpoint activation and induces genomic instability.
Volume: 183
Issue: 3
Pages: 385-91
Publication
First Author: Weiss RS
Year: 2002
Journal: Curr Biol
Title: Hus1 acts upstream of chk1 in a mammalian DNA damage response pathway.
Volume: 12
Issue: 1
Pages: 73-7
Publication
First Author: Smith KD
Year: 2009
Journal: J Cell Biol
Title: Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis.
Volume: 187
Issue: 1
Pages: 15-23
Publication
First Author: Rodier G
Year: 2015
Journal: Cell Rep
Title: The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions.
Volume: 11
Issue: 2
Pages: 220-33
Publication
First Author: Engelen E
Year: 2013
Journal: PLoS One
Title: Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clock.
Volume: 8
Issue: 2
Pages: e56623
Publication
First Author: Liu Q
Year: 2000
Journal: Genes Dev
Title: Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint.
Volume: 14
Issue: 12
Pages: 1448-59
Publication
First Author: Zheng L
Year: 2008
Journal: Blood
Title: TLR9 engagement on CD4 T lymphocytes represses gamma-radiation-induced apoptosis through activation of checkpoint kinase response elements.
Volume: 111
Issue: 5
Pages: 2704-13
Publication
First Author: López-Contreras AJ
Year: 2012
Journal: J Exp Med
Title: An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation.
Volume: 209
Issue: 3
Pages: 455-61
Publication
First Author: Weiss RS
Year: 2003
Journal: Mol Cell Biol
Title: Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint.
Volume: 23
Issue: 3
Pages: 791-803
Publication
First Author: Frauenstein K
Year: 2013
Journal: Cell Death Differ
Title: Evidence for a novel anti-apoptotic pathway in human keratinocytes involving the aryl hydrocarbon receptor, E2F1, and checkpoint kinase 1.
Volume: 20
Issue: 10
Pages: 1425-34
Publication
First Author: Hasthorpe S
Year: 2007
Journal: Mol Reprod Dev
Title: G2/M checkpoint gene expression in developing germ cells.
Volume: 74
Issue: 5
Pages: 531-8
Publication
First Author: Kang J
Year: 2005
Journal: Mol Cell Biol
Title: Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
Volume: 25
Issue: 2
Pages: 661-70
Publication
First Author: Cao L
Year: 2006
Journal: EMBO J
Title: ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.
Volume: 25
Issue: 10
Pages: 2167-77
Publication
First Author: Oshikawa M
Year: 2017
Journal: Development
Title: Dnmt1-dependent Chk1 pathway suppression is protective against neuron division.
Volume: 144
Issue: 18
Pages: 3303-3314
Publication
First Author: Nemajerova A
Year: 2007
Journal: EMBO J
Title: Impaired DNA damage checkpoint response in MIF-deficient mice.
Volume: 26
Issue: 4
Pages: 987-97
Publication
First Author: Origanti S
Year: 2013
Journal: Oncogene
Title: Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells.
Volume: 32
Issue: 5
Pages: 577-88
Publication
First Author: Dhomen N
Year: 2010
Journal: Pigment Cell Melanoma Res
Title: Inducible expression of (V600E) Braf using tyrosinase-driven Cre recombinase results in embryonic lethality.
Volume: 23
Issue: 1
Pages: 112-20
Publication
First Author: Gruber R
Year: 2011
Journal: Nat Cell Biol
Title: MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway.
Volume: 13
Issue: 11
Pages: 1325-34
Publication  
First Author: Gomes AL
Year: 2020
Journal: Front Cell Dev Biol
Title: RINT1 Loss Impairs Retinogenesis Through TRP53-Mediated Apoptosis.
Volume: 8
Pages: 711
Publication
First Author: Dong D
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Maternal diabetes triggers DNA damage and DNA damage response in neurulation stage embryos through oxidative stress.
Volume: 467
Issue: 2
Pages: 407-12
Publication
First Author: Zeng F
Year: 2004
Journal: Dev Biol
Title: Transcript profiling during preimplantation mouse development.
Volume: 272
Issue: 2
Pages: 483-96
Publication  
First Author: Dong MZ
Year: 2022
Journal: Development
Title: PPP4C facilitates homologous recombination DNA repair by dephosphorylating PLK1 during early embryo development.
Volume: 149
Issue: 10
Publication  
First Author: Xu C
Year: 2021
Journal: Sci Adv
Title: Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin.
Volume: 7
Issue: 27
Publication
First Author: Xu Q
Year: 2015
Journal: Development
Title: Maternal BCAS2 protects genomic integrity in mouse early embryonic development.
Volume: 142
Issue: 22
Pages: 3943-53
Publication
First Author: Hao L
Year: 2009
Journal: Biol Reprod
Title: The unfolded protein response contributes to preimplantation mouse embryo death in the DDK syndrome.
Volume: 80
Issue: 5
Pages: 944-53
Publication
First Author: Albino D
Year: 2011
Journal: Int J Dev Biol
Title: Gene expression profiling identifies eleven DNA repair genes down-regulated during mouse neural crest cell migration.
Volume: 55
Issue: 1
Pages: 65-72
Publication
First Author: Martínez P
Year: 2012
Journal: J Cell Biol
Title: 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.
Volume: 197
Issue: 2
Pages: 283-300
Publication
First Author: Kokavec J
Year: 2017
Journal: Stem Cells
Title: The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells.
Volume: 35
Issue: 6
Pages: 1614-1623
Publication
First Author: Sengupta S
Year: 2004
Journal: J Cell Biol
Title: Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.
Volume: 166
Issue: 6
Pages: 801-13
Publication  
First Author: Kafer GR
Year: 2020
Journal: Front Cell Dev Biol
Title: A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis.
Volume: 8
Pages: 416
Publication
First Author: Dewhurst MR
Year: 2020
Journal: PLoS Genet
Title: Loss of hepatocyte cell division leads to liver inflammation and fibrosis.
Volume: 16
Issue: 11
Pages: e1009084
Publication
First Author: Pirouz M
Year: 2013
Journal: PLoS Genet
Title: A critical function of Mad2l2 in primordial germ cell development of mice.
Volume: 9
Issue: 8
Pages: e1003712
Publication
First Author: Miles DC
Year: 2012
Journal: Dev Biol
Title: The proto-oncogene Ret is required for male foetal germ cell survival.
Volume: 365
Issue: 1
Pages: 101-9
Publication
First Author: D'Ignazio L
Year: 2018
Journal: Biol Reprod
Title: Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage.
Volume: 98
Issue: 4
Pages: 532-542
Publication
First Author: Ouseph MM
Year: 2012
Journal: Dev Cell
Title: Atypical E2F repressors and activators coordinate placental development.
Volume: 22
Issue: 4
Pages: 849-62
Publication
First Author: Lee Y
Year: 2012
Journal: Nat Neurosci
Title: Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors.
Volume: 15
Issue: 6
Pages: 819-26
Publication
First Author: Sutherland HG
Year: 2001
Journal: Hum Mol Genet
Title: Large-scale identification of mammalian proteins localized to nuclear sub-compartments.
Volume: 10
Issue: 18
Pages: 1995-2011
Publication
First Author: Lee Y
Year: 2012
Journal: EMBO J
Title: ATR maintains select progenitors during nervous system development.
Volume: 31
Issue: 5
Pages: 1177-89
Publication
First Author: Li R
Year: 2012
Journal: Cell Res
Title: A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons.
Volume: 22
Issue: 5
Pages: 859-72
Publication
First Author: Passemard S
Year: 2011
Journal: J Clin Invest
Title: VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling.
Volume: 121
Issue: 8
Pages: 3071-87
Publication
First Author: Tane S
Year: 2014
Journal: J Biol Chem
Title: Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes.
Volume: 289
Issue: 26
Pages: 18033-44
Publication  
First Author: Suzuki T
Year: 2019
Journal: Development
Title: Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.
Volume: 146
Issue: 4
Publication
First Author: Zhou L
Year: 2017
Journal: FASEB J
Title: Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.
Volume: 31
Issue: 1
Pages: 132-147
Publication
First Author: Zhang Q
Year: 2018
Journal: Cell Death Dis
Title: Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.
Volume: 9
Issue: 2
Pages: 247
Publication  
First Author: Akagawa R
Year: 2021
Journal: Front Cell Dev Biol
Title: Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.
Volume: 9
Pages: 753175
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
Publication      
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
Publication      
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
Publication      
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database