Type |
Details |
Score |
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
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•
•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
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Publication |
First Author: |
Takemoto K |
Year: |
2020 |
Journal: |
PLoS Genet |
Title: |
Sycp2 is essential for synaptonemal complex assembly, early meiotic recombination and homologous pairing in zebrafish spermatocytes. |
Volume: |
16 |
Issue: |
2 |
Pages: |
e1008640 |
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•
•
•
•
•
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Allele |
Name: |
synaptonemal complex protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Interaction Experiment |
Description: |
Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis. |
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Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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•
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Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of plant meiosis-specific proteins, such as AtASY3 from Arabidopsis and PAIR3 from rice. They are coiled-coil domain proteins required for normal meiosis []. PAIR3 is an axial element and part of the synaptonemal complex (SC) that forms between homologous chromosomes during meiosis []. Members of this family are homologues of SYCP2 from vertebrates and fungal Red1/Red10 []. |
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•
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Publication |
First Author: |
Ferdous M |
Year: |
2012 |
Journal: |
PLoS Genet |
Title: |
Inter-homolog crossing-over and synapsis in Arabidopsis meiosis are dependent on the chromosome axis protein AtASY3. |
Volume: |
8 |
Issue: |
2 |
Pages: |
e1002507 |
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•
•
•
•
•
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Publication |
First Author: |
Zhou L |
Year: |
2017 |
Journal: |
J Exp Bot |
Title: |
Bivalent Formation 1, a plant-conserved gene, encodes an OmpH/coiled-coil motif-containing protein required for meiotic recombination in rice. |
Volume: |
68 |
Issue: |
9 |
Pages: |
2163-2174 |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
253
 |
Fragment?: |
true |
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•
•
•
•
•
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Publication |
First Author: |
Kneissel S |
Year: |
2001 |
Journal: |
Mol Biol Cell |
Title: |
A novel karyoskeletal protein: characterization of protein NO145, the major component of nucleolar cortical skeleton in Xenopus oocytes. |
Volume: |
12 |
Issue: |
12 |
Pages: |
3904-18 |
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•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry includes synaptonemal complex protein 2 (SYCP2) and synaptonemal complex protein 2-like (SYCP2L).SYCP2 is one of the major components of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase [].SYCP2L has partial sequence homology to a SYCP2 and is the major component of nucleolar cortical skeleton in Xenopus oocytes []. In humans, SYCP2L promotes primordial oocytes survival, thus being associated with age at natural menopause (ANM) []. |
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Protein Domain |
Type: |
Domain |
Description: |
This entry represents coiled-coil domain of ASY3 and PAIR3.This entry represents a group of plant meiosis-specific proteins, such as AtASY3 from Arabidopsis and PAIR3 from rice. They are coiled-coil domain proteins required for normal meiosis []. PAIR3 is an axial element and part of the synaptonemal complex (SC) that forms between homologous chromosomes during meiosis []. Members of this family are homologues of SYCP2 from vertebrates and fungal Red1/Red10 []. |
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Publication |
First Author: |
Meuwissen RL |
Year: |
1992 |
Journal: |
EMBO J |
Title: |
A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes. |
Volume: |
11 |
Issue: |
13 |
Pages: |
5091-100 |
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•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Synaptonemal complex protein 2 (SYCP2) N-terminal region contains two separate subdomains an ARLD (armadillo-repeat-like domain) and an SLD (Spt16M-like domain). The ARLD domain belongs to the armadillo-repeat protein family. Armadillo-repeat units often form a superhelix, which typically provides a platform for many protein partners that transduce Wnt signaling, such as beta-catenin. The ARLD of mouse SYCP2 was found to associate with different protein partners, including CENP J and CENP F. ARLD structure is highly similar to that of the 'required for cell differentiation (RCD-1)' protein []. |
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•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
842
 |
Fragment?: |
false |
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•
•
•
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Publication |
First Author: |
Tromer EC |
Year: |
2021 |
Journal: |
Open Biol |
Title: |
Repurposing of synaptonemal complex proteins for kinetochores in Kinetoplastida. |
Volume: |
11 |
Issue: |
5 |
Pages: |
210049 |
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•
•
•
•
•
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Publication |
First Author: |
Feng J |
Year: |
2017 |
Journal: |
Protein Cell |
Title: |
Synaptonemal complex protein 2 (SYCP2) mediates the association of the centromere with the synaptonemal complex. |
Volume: |
8 |
Issue: |
7 |
Pages: |
538-543 |
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•
•
•
•
•
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Publication |
First Author: |
Fujiwara Y |
Year: |
2020 |
Journal: |
PLoS Genet |
Title: |
Meiotic cohesins mediate initial loading of HORMAD1 to the chromosomes and coordinate SC formation during meiotic prophase. |
Volume: |
16 |
Issue: |
9 |
Pages: |
e1009048 |
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•
•
•
•
•
|
Publication |
First Author: |
Xu H |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Molecular organization of mammalian meiotic chromosome axis revealed by expansion STORM microscopy. |
Volume: |
116 |
Issue: |
37 |
Pages: |
18423-18428 |
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•
•
•
•
•
|
Publication |
First Author: |
Li XC |
Year: |
2011 |
Journal: |
Genetics |
Title: |
Genetic evidence that synaptonemal complex axial elements govern recombination pathway choice in mice. |
Volume: |
189 |
Issue: |
1 |
Pages: |
71-82 |
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