Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:4423676 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826558 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009374_21 |
|
Specimen Label: |
euxassay_009374_21 |
Detected: |
true |
Specimen Num: |
21 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423676 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826558 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009374_22 |
|
Specimen Label: |
euxassay_009374_22 |
Detected: |
true |
Specimen Num: |
22 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423676 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826558 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009374_23 |
|
Specimen Label: |
euxassay_009374_23 |
Detected: |
true |
Specimen Num: |
23 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3527866 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-02-28 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796222 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:3527867 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
E14.5 ovary |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sever-Chroneos Z |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Surfactant protein A (SP-A)-mediated clearance of Staphylococcus aureus involves binding of SP-A to the staphylococcal adhesin eap and the macrophage receptors SP-A receptor 210 and scavenger receptor class A. |
Volume: |
286 |
Issue: |
6 |
Pages: |
4854-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alexander CJ |
Year: |
2021 |
Journal: |
FASEB J |
Title: |
Myosin 18Aα targets the guanine nucleotide exchange factor β-Pix to the dendritic spines of cerebellar Purkinje neurons and promotes spine maturation. |
Volume: |
35 |
Issue: |
1 |
Pages: |
e21092 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trost M |
Year: |
2009 |
Journal: |
Immunity |
Title: |
The phagosomal proteome in interferon-gamma-activated macrophages. |
Volume: |
30 |
Issue: |
1 |
Pages: |
143-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu TY |
Year: |
2017 |
Journal: |
Open Biol |
Title: |
Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice. |
Volume: |
7 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Revenu C |
Year: |
2012 |
Journal: |
Mol Biol Cell |
Title: |
A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins. |
Volume: |
23 |
Issue: |
2 |
Pages: |
324-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wertz K |
Year: |
2000 |
Journal: |
Mech Dev |
Title: |
Large-scale screen for genes involved in gonad development. |
Volume: |
98 |
Issue: |
1-2 |
Pages: |
51-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toronto Centre for Phenogenomics |
Year: |
2013 |
Journal: |
MGI Direct Data Submission |
Title: |
Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson ME |
Year: |
2016 |
Journal: |
Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
Volume: |
537 |
Issue: |
7621 |
Pages: |
508-514 |
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mori K |
Year: |
2003 |
Journal: |
J Biochem |
Title: |
Genome structure and differential expression of two isoforms of a novel PDZ-containing myosin (MysPDZ) (Myo18A). |
Volume: |
133 |
Issue: |
4 |
Pages: |
405-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mori K |
Year: |
2005 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Subcellular localization and dynamics of MysPDZ (Myo18A) in live mammalian cells. |
Volume: |
326 |
Issue: |
2 |
Pages: |
491-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guzik-Lendrum S |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Drosophila melanogaster myosin-18 represents a highly divergent motor with actin tethering properties. |
Volume: |
286 |
Issue: |
24 |
Pages: |
21755-66 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Many members of myosin class XVIII contain an N-terminal PDZ domain which is commonly found in proteins establishing molecular complexes. Mammals express a second isoform, Myo18B, that lacks the PDZ domain []. They also contain a motor domain which does not exhibit ATPase activity, suggesting that these myosins function as an actin tether protein [, ]. They also have two IQ domains that probably bind light chains or related calmodulins and a C-terminal tail with two sections of coiled-coil domains, which are thought to mediate homodimerization []. Myo18A has been implicated in stromal cell differentiation []and Myo18B in tumor suppression [].This entry represents the motor domain. |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishioka M |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer. |
Volume: |
99 |
Issue: |
19 |
Pages: |
12269-74 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
745
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1357
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2605
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|