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Search results 2701 to 2739 out of 2739 for Kdr

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0.023s

Type

Details

Score

Publication

11710594 | -

First Author:	Chattopadhyay N
Year:	2001
Journal:	J Cancer Res Clin Oncol
Title:	Human cervical tumor cell (SiHa) surface alphavbeta3 integrin receptor has associated matrix metalloproteinase (MMP-2) activity.
Volume:	127
Issue:	11
Pages:	653-8

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Protein Domain

IPR015613 | TIMP2

Type:

Family

Description:

TIMP-2 is a serine protease inhibitor that inhibits MMPs. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19 []. As opposed to other TIMPs, TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. These effects require alpha 3 beta 1 integrin-mediated binding of TIMP-2 to endothelial cells. Further, TIMP-2 induces a decrease in total protein tyrosine phosphatase (PTP) activity associated with beta1 integrin subunits as well as dissociation of the phosphatase SHP-1 from beta1. TIMP-2 treatment also results in a concomitant increase in PTP activity associated with tyrosine kinase receptors FGFR-1 and KDR [].Tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of matrix metalloproteinases (MMPs) found in most tissues and body fluids. By inhibiting MMPs activities, they participate in tissue remodeling of the extracellular matrix (ECM). The balance between MMPs and TIMPs activities is involved in both normal and pathological events such as wound healing, tissue remodeling, angiogenesis, invasion, tumourigenesis and metastasis []. TIMPs also exhibit functions that appear to be independent of their metalloproteinase inhibitory capacity []. There are four mammalian TIMPs (TIMP-1 to -4), and each TIMP has its own profile of metalloproteinase inhibition.

•

Publication

22438826 | J:183476

First Author:	Jameson SA
Year:	2012
Journal:	PLoS Genet
Title:	Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad.
Volume:	8
Issue:	3
Pages:	e1002575

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Allele

Gt(ROSA)26Sor<tm4(CAG-EYFP*,-tdTomato*,-KDR*,-mEYFP*,-Kdr*,-mKate2*)Ben> | MGI:6759810

Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Rui Benedito
Allele Type:	Targeted
Attribute String:	Conditional ready, Reporter

•

Genotype

Symbol:	Aplnr/Aplnr Tg(Kdr-cre)#Brei/?
Background:	involves: C57BL/6
Zygosity:	cn
Has Mutant Allele:	true

•

Publication

34475534 | J:325307

First Author:	Choi J
Year:	2021
Journal:	Nat Cell Biol
Title:	Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration.
Volume:	23
Issue:	9
Pages:	953-966

•

Publication

35027734 | J:321043

First Author:	Das A
Year:	2022
Journal:	Nat Cell Biol
Title:	Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis.
Volume:	24
Issue:	1
Pages:	35-50

•

Publication

24048574 | J:204009

First Author:	Winterhager E
Year:	2013
Journal:	Biol Reprod
Title:	Decidual angiogenesis and placental orientation are altered in mice heterozygous for a dominant loss-of-function Gja1 (connexin43) mutation.
Volume:	89
Issue:	5
Pages:	111

•

Publication

35314385 | J:322829

First Author:	Taylor EL
Year:	2022
Journal:	Bone
Title:	GIRK3 deletion facilitates kappa opioid signaling in chondrocytes, delays vascularization and promotes bone lengthening in mice.
Volume:	159

Pages:	116391

•

Publication

36512424 | J:336135

First Author:	Tang X
Year:	2023
Journal:	J Clin Invest
Title:	Long noncoding RNA LEENE promotes angiogenesis and ischemic recovery in diabetes models.
Volume:	133
Issue:	3

•

Publication

28757617 | J:249411

First Author:	Hadzijusufovic E
Year:	2017
Journal:	Leukemia
Title:	Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site.
Volume:	31
Issue:	11
Pages:	2388-2397

•

Publication

12107087 | J:77978

First Author:	Shih SC
Year:	2002
Journal:	Am J Pathol
Title:	Molecular profiling of angiogenesis markers.
Volume:	161
Issue:	1
Pages:	35-41

•

Publication

17462595 | J:121775

First Author:	Narumiya H
Year:	2007
Journal:	Biochem Biophys Res Commun
Title:	Endocardiogenesis in embryoid bodies: novel markers identified by gene expression profiling.
Volume:	357
Issue:	4
Pages:	896-902

•

Publication

30024304 | J:265831

First Author:	Good RJ
Year:	2018
Journal:	Am J Physiol Lung Cell Mol Physiol
Title:	MicroRNA dysregulation in lung injury: the role of the miR-26a/EphA2 axis in regulation of endothelial permeability.
Volume:	315
Issue:	4
Pages:	L584-L594

•

Publication

30601675 | J:289121

First Author:	Wang Y
Year:	2019
Journal:	FASEB J
Title:	High levels of HtrA4 detected in preeclamptic circulation may disrupt endothelial cell function by cleaving the main VEGFA receptor KDR.
Volume:	33
Issue:	4
Pages:	5058-5066

•

Publication

30258227 | J:266626

First Author:	Lorenz L
Year:	2018
Journal:	Nature
Title:	Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival.
Volume:	562
Issue:	7725
Pages:	128-132

•

Publication

36240771 | J:330969

First Author:	Martins LF
Year:	2022
Journal:	Neuron
Title:	Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.

•

Publication

25062690 | J:227456

First Author:	Lathen C
Year:	2014
Journal:	Circulation
Title:	ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease.
Volume:	130
Issue:	14
Pages:	1179-91

•

Publication

29026147 | J:256372

First Author:	Nagao M
Year:	2017
Journal:	Sci Rep
Title:	Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis.
Volume:	7
Issue:	1
Pages:	13027

•

Allele

TgTn(pb-Gt(ROSA)26Sor/CAG-EYFP*,-tdTomato*,-KDR*,-mEYFP*,-Kdr*,-mKate2*)#Ben | MGI:6761550

Name:	transgenic transposon concatemer, Rui Benedito
Allele Type:	Transgenic
Attribute String:	Conditional ready, Epitope tag, Inserted expressed sequence, Reporter, Transposon concatemer

•

Genotype

Symbol:	Kdr/Kdr<+> Tg(tetO-Kdr*)4377.5Rwng/? Tg(Cebpb-tTA)5Bjd/?
Background:	involves: 129S1/Sv * 129X1/SvJ * FVB/N * NMRI
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Kdr-cre)15962Brei/?
Background:	involves: 129S4/SvJaeSor * C57BL/6
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Kdr-cre)15964Brei/?
Background:	involves: 129S4/SvJaeSor * C57BL/6
Zygosity:	cn
Has Mutant Allele:	true

•

Publication

11221852 | J:68578

First Author:	Hiratsuka S
Year:	2001
Journal:	Cancer Res
Title:	Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis.
Volume:	61
Issue:	3
Pages:	1207-13

•

Publication

29342188 | J:258235

First Author:	Deveza L
Year:	2018
Journal:	PLoS One
Title:	Comparative analysis of gene expression identifies distinct molecular signatures of bone marrow- and periosteal-skeletal stem/progenitor cells.
Volume:	13
Issue:	1
Pages:	e0190909

•

Publication

25912686 | J:239280

First Author:	Poché RA
Year:	2015
Journal:	Dev Biol
Title:	Macrophages engulf endothelial cell membrane particles preceding pupillary membrane capillary regression.
Volume:	403
Issue:	1
Pages:	30-42

•

Publication

22865640 | J:202652

First Author:	Yang J
Year:	2012
Journal:	Cardiovasc Res
Title:	Inhibition of Notch2 by Numb/Numblike controls myocardial compaction in the heart.
Volume:	96
Issue:	2
Pages:	276-85

•

Publication

14745955 | J:88924

First Author:	Licht AH
Year:	2004
Journal:	Dev Dyn
Title:	Endothelium-specific Cre recombinase activity in flk-1-Cre transgenic mice.
Volume:	229
Issue:	2
Pages:	312-8

•

Publication

27981571 | J:241898

First Author:	Van Welden S
Year:	2017
Journal:	J Pathol
Title:	Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Volume:	241
Issue:	4
Pages:	547-558

•

Protein

P25785

Organism:	Mus musculus/domesticus
Length:	220
Fragment?:	false

•

Protein

Q8BSJ3

Organism:	Mus musculus/domesticus
Length:	220
Fragment?:	false

•

Protein

Q6GXA8

Organism:	Mus musculus/domesticus
Length:	95
Fragment?:	true

•

Protein

B1AQJ3

Organism:	Mus musculus/domesticus
Length:	143
Fragment?:	true

•

Protein

Q6PI17

Organism:	Mus musculus/domesticus
Length:	220
Fragment?:	false

•

Publication

15036259 | -

First Author:	Lambert E
Year:	2004
Journal:	Crit Rev Oncol Hematol
Title:	TIMPs as multifacial proteins.
Volume:	49
Issue:	3
Pages:	187-98

•

Publication

27031698 | J:249149

First Author:	Huang W
Year:	2016
Journal:	PLoS One
Title:	Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.
Volume:	11
Issue:	3
Pages:	e0152833

•

Publication

24912173 | J:211622

First Author:	DeFalco T
Year:	2014
Journal:	Proc Natl Acad Sci U S A
Title:	Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis.
Volume:	111
Issue:	23
Pages:	E2384-93

•

Publication

37972594 | J:344401

First Author:	Bhat GP
Year:	2024
Journal:	Neuron
Title:	Structured wound angiogenesis instructs mesenchymal barrier compartments in the regenerating nerve.
Volume:	112
Issue:	2
Pages:	209-229.e11

•

Publication

28802047 | J:252386

First Author:	Pontes-Quero S
Year:	2017
Journal:	Cell
Title:	Dual ifgMosaic: A Versatile Method for Multispectral and Combinatorial Mosaic Gene-Function Analysis.
Volume:	170
Issue:	4
Pages:	800-814.e18

•

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Search results 2701 to 2739 out of 2739 for Kdr

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