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Search results 201 to 278 out of 278 for Cnot1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4428188
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422535
Age: embryonic day 14.5
Image: MH2950; Specimen C4087
Specimen Label: MH2950; Specimen C4087
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4428188
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422535
Age: embryonic day 14.5
Image: MH2950; Specimen C4087
Specimen Label: MH2950; Specimen C4087
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4428188
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5422535
Age: embryonic day 14.5
Specimen Label: MH2950; Specimen C4087
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4428188
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1802422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422535
Age: embryonic day 14.5
Image: MH2950; Specimen C4087
Specimen Label: MH2950; Specimen C4087
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4428188
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422535
Age: embryonic day 14.5
Image: MH2950; Specimen C4087
Note: Expression was strong in the skull (base and vault).
Specimen Label: MH2950; Specimen C4087
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4428188
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422535
Age: embryonic day 14.5
Image: MH2950; Specimen C4087
Note: Expression was strong in whisker follicle.
Specimen Label: MH2950; Specimen C4087
Detected: true
Specimen Num: 1
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Publication
22367759 | J:196241
First Author: Zheng X
Year: 2012
Journal: Stem Cells
Title: Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation.
Volume: 30
Issue: 5
Pages: 910-22
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Publication
17452450 | J:143628
First Author: Morita M
Year: 2007
Journal: Mol Cell Biol
Title: Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth.
Volume: 27
Issue: 13
Pages: 4980-90
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Publication
31924127 | J:304598
First Author: Mostafa D
Year: 2020
Journal: RNA Biol
Title: Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability.
Volume: 17
Issue: 3
Pages: 403-416
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Publication
21741365 | J:174695
First Author: Chen C
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Distinct expression patterns of the subunits of the CCR4-NOT deadenylase complex during neural development.
Volume: 411
Issue: 2
Pages: 360-4
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Publication
20133598 | J:157579
First Author: Suzuki A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs.
Volume: 107
Issue: 8
Pages: 3594-9
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Publication
27618784 | J:238760
First Author: Dominick G
Year: 2017
Journal: Aging Cell
Title: mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice.
Volume: 16
Issue: 1
Pages: 52-60
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Publication
26589352 | J:230058
First Author: Suzuki A
Year: 2016
Journal: EMBO Rep
Title: Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development.
Volume: 17
Issue: 1
Pages: 37-46
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Publication
22448252 | J:187029
First Author: Suzuki A
Year: 2012
Journal: PLoS One
Title: Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse.
Volume: 7
Issue: 3
Pages: e33558
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Publication
30733279 | J:272586
 
First Author: Suzuki T
Year: 2019
Journal: Development
Title: Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.
Volume: 146
Issue: 4
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Publication
38822427 | J:350444
First Author: Martinez-Mayer J
Year: 2024
Journal: Genome Med
Title: Knockout mice with pituitary malformations help identify human cases of hypopituitarism.
Volume: 16
Issue: 1
Pages: 75
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Publication
22008794 | J:143778
First Author: Tamplin OJ
Year: 2011
Journal: Dev Biol
Title: Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.
Volume: 360
Issue: 2
Pages: 415-25
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Cnot1<tm1.1Tya> | MGI:6695738
Name: CCR4-NOT transcription complex, subunit 1; targeted mutation 1.1, Tadashi Yamamoto
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
31036567 | J:289732
 
First Author: Lai WS
Year: 2019
Journal: Mol Cell Biol
Title: Importance of the Conserved Carboxyl-Terminal CNOT1 Binding Domain to Tristetraprolin Activity In Vivo.
Volume: 39
Issue: 13
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DO Term
DOID:0081397 | Vissers-Bodmer syndrome
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DO Term
DOID:0081398 | holoprosencephaly 12
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Publication
23232451 | J:196333
First Author: Mauxion F
Year: 2013
Journal: RNA Biol
Title: C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex.
Volume: 10
Issue: 2
Pages: 267-76
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Protein
Q9CWN7
Organism: Mus musculus/domesticus
Length: 505  
Fragment?: false
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Protein
Q8C9T0
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: true
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Protein
A0A0A6YW44
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
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Publication
23303381 | -
First Author: Bawankar P
Year: 2013
Journal: RNA Biol
Title: NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain.
Volume: 10
Issue: 2
Pages: 228-44
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Protein Domain
IPR019312 | CNOT11
Type: Family
Description: The CCR4-NOT complex plays a key role in mRNA decay in all eukaryotes, thereby contributing importantly to gene expression regulation []. Human C2ORF29 proteins, also known as CNOT11, is a component of the CCR4-NOT complex. CNOT11 interacts with the first amino acids of CNOT1 and with CNOT10 and is required for the association of CNOT10 with the CCR4-NOT complex [].
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Publication
37820724 | J:355112
First Author: Shen M
Year: 2023
Journal: Neuron
Title: Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development.
Volume: 111
Issue: 24
Pages: 3988-4005.e11
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Publication
25416063 | J:217384
First Author: Suzuki A
Year: 2014
Journal: Biol Open
Title: Interaction of NANOS2 and NANOS3 with different components of the CNOT complex may contribute to the functional differences in mouse male germ cells.
Volume: 3
Issue: 12
Pages: 1207-16
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Publication
33199444 | J:301042
 
First Author: Wright D
Year: 2021
Journal: Development
Title: Genetic and structural analysis of the in vivo functional redundancy between murine NANOS2 and NANOS3.
Volume: 148
Issue: 1
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Publication
16971515 | -
First Author: DeBella LR
Year: 2006
Journal: Mol Biol Cell
Title: LET-711, the Caenorhabditis elegans NOT1 ortholog, is required for spindle positioning and regulation of microtubule length in embryos.
Volume: 17
Issue: 11
Pages: 4911-24
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Publication
32553196 | -
First Author: Vissers LELM
Year: 2020
Journal: Am J Hum Genet
Title: De Novo Variants in CNOT1, a Central Component of the CCR4-NOT Complex Involved in Gene Expression and RNA and Protein Stability, Cause Neurodevelopmental Delay.
Volume: 107
Issue: 1
Pages: 164-172
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Protein Domain
IPR040398 | Not1
Type: Family
Description: Not1 is the core component of the CCR4/NOT complex, which plays roles in the negative regulation of gene expression at transcriptional and post-transcriptional levels. This entry includes Not1 (also known as Cdc39) and its homologues, such as LET-711 from Caenorhabditis elegans []. De novo variants in CNOT1 have been shown to cause neurodevelopmental delay []. The Ccr4-Not complex is a global regulator of gene expression that is conserved from yeast to human. It affects genes positively and negatively and is thought to regulate transcription factor IID function. In Saccharomyces cerevisiae, it exists in two prominent forms and consists of at least nine core subunits: the five Not proteins (Not1 to Not5), Caf1, Caf40, Caf130 and Ccr4 []. The Ccr4-Not complex regulates many different cellular functions, including RNA degradation and transcription initiation. It may be a regulatory platform that senses nutrient levels and stress []. Caf1 and Ccr4, are directly involved in mRNA deadenylation, and Caf1p is associated with Dhh1, a putative RNA helicase thought to be a component of the decapping complex []. Pop2, a component of the Ccr4-Not complex, functions as a deadenylase [].
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Protein
A0A1D5RML9
Organism: Mus musculus/domesticus
Length: 823  
Fragment?: true
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Protein
A0A1D5RMD8
Organism: Mus musculus/domesticus
Length: 1614  
Fragment?: false
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Protein
Q6ZQ08
Organism: Mus musculus/domesticus
Length: 2375  
Fragment?: false
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Protein
A0A1D5RMJ8
Organism: Mus musculus/domesticus
Length: 2369  
Fragment?: false
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Publication
11696541 | -
First Author: Maillet L
Year: 2002
Journal: J Biol Chem
Title: Interaction between Not1p, a component of the Ccr4-not complex, a global regulator of transcription, and Dhh1p, a putative RNA helicase.
Volume: 277
Issue: 4
Pages: 2835-42
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Publication
12957374 | -
 
First Author: Collart MA
Year: 2003
Journal: Gene
Title: Global control of gene expression in yeast by the Ccr4-Not complex.
Volume: 313
Pages: 1-16
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Publication
18430587 | -
First Author: Liu WF
Year: 2008
Journal: Protein Expr Purif
Title: Biophysical and biochemical characterization of recombinant human Pop2 deadenylase.
Volume: 60
Issue: 1
Pages: 46-52
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Publication
10637334 | -
First Author: Albert TK
Year: 2000
Journal: Nucleic Acids Res
Title: Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.
Volume: 28
Issue: 3
Pages: 809-17
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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