Type |
Details |
Score |
Publication |
First Author: |
Pineau T |
Year: |
1995 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2. |
Volume: |
92 |
Issue: |
11 |
Pages: |
5134-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salmond RJ |
Year: |
2011 |
Journal: |
Blood |
Title: |
Mislocalization of Lck impairs thymocyte differentiation and can promote development of thymomas. |
Volume: |
117 |
Issue: |
1 |
Pages: |
108-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yada S |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
Differential requirements of CD45 protein tyrosine phosphatase for cytolytic activities and intrathymic and extrathymic development of intestinal intraepithelial lymphocytes. |
Volume: |
161 |
Issue: |
5 |
Pages: |
2208-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Würch A |
Year: |
1998 |
Journal: |
J Exp Med |
Title: |
Requirement of CD3 complex-associated signaling functions for expression of rearranged T cell receptor beta VDJ genes in early thymic development. |
Volume: |
188 |
Issue: |
9 |
Pages: |
1669-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao R |
Year: |
2004 |
Journal: |
Cancer Cell |
Title: |
An oncogenic tyrosine kinase inhibits DNA repair and DNA-damage-induced Bcl-xL deamidation in T cell transformation. |
Volume: |
5 |
Issue: |
1 |
Pages: |
37-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fukushima A |
Year: |
2005 |
Journal: |
Immunogenetics |
Title: |
Mice lacking the IFN-gamma receptor or fyn develop severe experimental autoimmune uveoretinitis characterized by different immune responses. |
Volume: |
57 |
Issue: |
5 |
Pages: |
337-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawashima T |
Year: |
2021 |
Journal: |
J Neurochem |
Title: |
Phosphorylation of Collapsin Response Mediator Protein 1 (CRMP1) at Tyrosine 504 residue regulates Semaphorin 3A-induced cortical dendritic growth. |
Volume: |
157 |
Issue: |
4 |
Pages: |
1207-1221 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yokoyama K |
Year: |
2006 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Phosphorylation at Tyr-694 of Nogo-A by Src-family kinases. |
Volume: |
349 |
Issue: |
4 |
Pages: |
1401-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stephen TL |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold. |
Volume: |
109 |
Issue: |
19 |
Pages: |
7415-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Appleby MW |
Year: |
1995 |
Journal: |
J Exp Med |
Title: |
Involvement of p59fynT in interleukin-5 receptor signaling. |
Volume: |
182 |
Issue: |
3 |
Pages: |
811-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seavitt JR |
Year: |
1999 |
Journal: |
Mol Cell Biol |
Title: |
Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development. |
Volume: |
19 |
Issue: |
6 |
Pages: |
4200-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang H |
Year: |
2012 |
Journal: |
J Neurosci Res |
Title: |
Myosin II is a negative regulator of oligodendrocyte morphological differentiation. |
Volume: |
90 |
Issue: |
8 |
Pages: |
1547-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Linette GP |
Year: |
1995 |
Journal: |
Blood |
Title: |
Peripheral T-cell lymphoma in lckpr-bcl-2 transgenic mice. |
Volume: |
86 |
Issue: |
4 |
Pages: |
1255-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tran DD |
Year: |
2005 |
Journal: |
Immunity |
Title: |
CAML is a p56Lck-interacting protein that is required for thymocyte development. |
Volume: |
23 |
Issue: |
2 |
Pages: |
139-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hasegawa K |
Year: |
2004 |
Journal: |
Science |
Title: |
PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells. |
Volume: |
303 |
Issue: |
5658 |
Pages: |
685-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yam-Puc JC |
Year: |
2021 |
Journal: |
iScience |
Title: |
Enhanced BCR signaling inflicts early plasmablast and germinal center B cell death. |
Volume: |
24 |
Issue: |
2 |
Pages: |
102038 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chrobak P |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
HIV-1 Nef disrupts maturation of CD4+ T cells through CD4/Lck modulation. |
Volume: |
185 |
Issue: |
7 |
Pages: |
3948-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Drake CG |
Year: |
1994 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB x NZW)F1 mice. |
Volume: |
91 |
Issue: |
9 |
Pages: |
4062-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li JP |
Year: |
2014 |
Journal: |
Nat Commun |
Title: |
The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck. |
Volume: |
5 |
|
Pages: |
3618 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang X |
Year: |
2007 |
Journal: |
Cell Death Differ |
Title: |
Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival. |
Volume: |
14 |
Issue: |
2 |
Pages: |
368-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Campbell KS |
Year: |
1995 |
Journal: |
Ann N Y Acad Sci |
Title: |
Interaction of p56lck with CD4 in the yeast two-hybrid system. |
Volume: |
766 |
|
Pages: |
89-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JM |
Year: |
1996 |
Journal: |
Oncogene |
Title: |
Association of CD45 with Lck and components of the Ras signalling pathway in pervanadate-treated mouse T-cell lines. |
Volume: |
12 |
Issue: |
2 |
Pages: |
253-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mori T |
Year: |
1992 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Expression of the signal transducing regions of CD4-like and lck genes in murine egg. |
Volume: |
182 |
Issue: |
2 |
Pages: |
527-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lefebvre DC |
Year: |
2003 |
Journal: |
Biochim Biophys Acta |
Title: |
The noncatalytic domains of Lck regulate its dephosphorylation by CD45. |
Volume: |
1650 |
Issue: |
1-2 |
Pages: |
40-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Canela A |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice. |
Volume: |
24 |
Issue: |
10 |
Pages: |
4275-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nie G |
Year: |
2005 |
Journal: |
Blood |
Title: |
Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis. |
Volume: |
105 |
Issue: |
5 |
Pages: |
2161-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Expression of CD45 lacking the catalytic protein tyrosine phosphatase domain modulates Lck phosphorylation and T cell activation. |
Volume: |
280 |
Issue: |
14 |
Pages: |
14318-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen IJ |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling. |
Volume: |
282 |
Issue: |
48 |
Pages: |
35361-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pires de Miranda M |
Year: |
2008 |
Journal: |
PLoS One |
Title: |
The Gammaherpesvirus m2 protein manipulates the Fyn/Vav pathway through a multidocking mechanism of assembly. |
Volume: |
3 |
Issue: |
2 |
Pages: |
e1654 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frasson M |
Year: |
2009 |
Journal: |
Biochim Biophys Acta |
Title: |
Grp94 is Tyr-phosphorylated by Fyn in the lumen of the endoplasmic reticulum and translocates to Golgi in differentiating myoblasts. |
Volume: |
1793 |
Issue: |
2 |
Pages: |
239-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hashimoto-Tane A |
Year: |
2010 |
Journal: |
Mol Cell Biol |
Title: |
T-cell receptor microclusters critical for T-cell activation are formed independently of lipid raft clustering. |
Volume: |
30 |
Issue: |
14 |
Pages: |
3421-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bae H |
Year: |
2010 |
Journal: |
Toxicol Sci |
Title: |
Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes. |
Volume: |
115 |
Issue: |
2 |
Pages: |
444-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki R |
Year: |
2010 |
Journal: |
J Leukoc Biol |
Title: |
Loss of TRPC1-mediated Ca2+ influx contributes to impaired degranulation in Fyn-deficient mouse bone marrow-derived mast cells. |
Volume: |
88 |
Issue: |
5 |
Pages: |
863-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato M |
Year: |
2011 |
Journal: |
Int Immunol |
Title: |
Identification of Fyn as the binding partner for the WASP N-terminal domain in T cells. |
Volume: |
23 |
Issue: |
8 |
Pages: |
493-502 |
|
•
•
•
•
•
|
Publication |
First Author: |
Venkitachalam S |
Year: |
2012 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Nuclear localization of lymphocyte-specific protein tyrosine kinase (Lck) and its role in regulating LIM domain only 2 (Lmo2) gene. |
Volume: |
417 |
Issue: |
3 |
Pages: |
1058-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elliott RW |
Year: |
1992 |
Journal: |
Mouse Genome |
Title: |
High resolution blot analysis of alleles for Glut-1 in RI strains |
Volume: |
90 |
Issue: |
3 |
Pages: |
428-29 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
459
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
322
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
217
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
559
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
303
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gross JA |
Year: |
1990 |
Journal: |
J Immunol |
Title: |
The murine homologue of the T lymphocyte antigen CD28. Molecular cloning and cell surface expression. |
Volume: |
144 |
Issue: |
8 |
Pages: |
3201-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lammers M |
Year: |
2005 |
Journal: |
EMBO J |
Title: |
The regulation of mDia1 by autoinhibition and its release by Rho*GTP. |
Volume: |
24 |
Issue: |
23 |
Pages: |
4176-87 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
829
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
820
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
304
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
217
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
461
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi N |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain. |
Volume: |
279 |
Issue: |
6 |
Pages: |
4962-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ong SH |
Year: |
2000 |
Journal: |
Mol Cell Biol |
Title: |
FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. |
Volume: |
20 |
Issue: |
3 |
Pages: |
979-89 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
297
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
903
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
854
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
763
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
756
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
793
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
550
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
603
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
454
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
204
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
304
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
559
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
624
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
277
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
68
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
322
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
461
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
166
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
90
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
203
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
858
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
269
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
658
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
146
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
502
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
126
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
129
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
441
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
217
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
224
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
806
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
559
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
402
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
774
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
304
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
615
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
254
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
351
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
283
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
749
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
252
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
624
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
217
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
243
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
303
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
461
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
468
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
603
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
559
 |
Fragment?: |
false |
|
•
•
•
•
•
|