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Search results 1801 to 1900 out of 2570 for Kras

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Category: Publication
Type Details Score
Publication  
First Author: Gundry C
Year: 2017
Journal: Nat Commun
Title: Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.
Volume: 8
Pages: 14646
Publication
First Author: Ahmad I
Year: 2011
Journal: Dis Model Mech
Title: K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder.
Volume: 4
Issue: 4
Pages: 548-55
Publication
First Author: Singh M
Year: 2012
Journal: J Pathol
Title: Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models.
Volume: 227
Issue: 4
Pages: 417-30
Publication
First Author: Lo B
Year: 2012
Journal: J Cell Biol
Title: Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.
Volume: 199
Issue: 7
Pages: 1117-30
Publication
First Author: Shakya R
Year: 2011
Journal: Science
Title: BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
Volume: 334
Issue: 6055
Pages: 525-8
Publication
First Author: Hingorani SR
Year: 2005
Journal: Cancer Cell
Title: Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice.
Volume: 7
Issue: 5
Pages: 469-83
Publication
First Author: Wang VM
Year: 2019
Journal: Nat Cell Biol
Title: CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth.
Volume: 21
Issue: 11
Pages: 1425-1435
Publication
First Author: Perkail S
Year: 2020
Journal: Nat Commun
Title: BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice.
Volume: 11
Issue: 1
Pages: 3018
Publication
First Author: Kogler M
Year: 2020
Journal: Cancer Res
Title: HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
Volume: 80
Issue: 14
Pages: 3009-3022
Publication
First Author: Fukuda A
Year: 2011
Journal: Cancer Cell
Title: Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.
Volume: 19
Issue: 4
Pages: 441-55
Publication
First Author: Harris IS
Year: 2015
Journal: Cancer Cell
Title: Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.
Volume: 27
Issue: 2
Pages: 211-22
Publication
First Author: Liu W
Year: 2012
Journal: Cancer Cell
Title: LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma.
Volume: 21
Issue: 6
Pages: 751-64
Publication  
First Author: Demir IE
Year: 2014
Journal: J Natl Cancer Inst
Title: Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion.
Volume: 106
Issue: 8
Publication
First Author: Nakayama M
Year: 2017
Journal: Oncogene
Title: Intestinal cancer progression by mutant p53 through the acquisition of invasiveness associated with complex glandular formation.
Volume: 36
Issue: 42
Pages: 5885-5896
Publication
First Author: Fatehullah A
Year: 2021
Journal: Nat Cell Biol
Title: A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers.
Volume: 23
Issue: 12
Pages: 1299-1313
Publication
First Author: Jackstadt R
Year: 2019
Journal: Cancer Cell
Title: Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
Volume: 36
Issue: 3
Pages: 319-336.e7
Publication
First Author: Ustiyan V
Year: 2016
Journal: Dev Dyn
Title: β-catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis.
Volume: 245
Issue: 5
Pages: 590-604
Publication
First Author: Yi Y
Year: 2015
Journal: J Urol
Title: A Murine Model of K-RAS and β-Catenin Induced Renal Tumors Expresses High Levels of E2F1 and Resembles Human Wilms Tumor.
Volume: 194
Issue: 6
Pages: 1762-70
Publication
First Author: Das S
Year: 2020
Journal: Cancer Res
Title: Tumor Cell-Derived IL1β Promotes Desmoplasia and Immune Suppression in Pancreatic Cancer.
Volume: 80
Issue: 5
Pages: 1088-1101
Publication    
First Author: Park MD
Year: 2024
Journal: Science
Title: Hematopoietic aging promotes cancer by fueling IL-1⍺-driven emergency myelopoiesis.
Pages: eadn0327
Publication
First Author: Liu L
Year: 2018
Journal: Cell Rep
Title: The LIS1/NDE1 Complex Is Essential for FGF Signaling by Regulating FGF Receptor Intracellular Trafficking.
Volume: 22
Issue: 12
Pages: 3277-3291
Publication
First Author: Seidlitz T
Year: 2019
Journal: Gastroenterology
Title: Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations.
Volume: 157
Issue: 6
Pages: 1599-1614.e2
Publication
First Author: Bednar F
Year: 2015
Journal: Carcinogenesis
Title: Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.
Volume: 36
Issue: 7
Pages: 730-8
Publication  
First Author: Han X
Year: 2014
Journal: Nat Commun
Title: Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma.
Volume: 5
Pages: 3261
Publication
First Author: Tomita H
Year: 2021
Journal: Cell Rep
Title: Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas.
Volume: 34
Issue: 8
Pages: 108772
Publication      
First Author: Liu J
Year: 2015
Journal: Cell Rep
Title: ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.
Publication
First Author: Baek ST
Year: 2012
Journal: Development
Title: Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation.
Volume: 139
Issue: 11
Pages: 2040-9
Publication
First Author: Sabra H
Year: 2017
Journal: J Biol Chem
Title: β1 integrin-dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin.
Volume: 292
Issue: 47
Pages: 19179-19197
Publication
First Author: Boumahdi S
Year: 2014
Journal: Nature
Title: SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.
Volume: 511
Issue: 7508
Pages: 246-50
Publication  
First Author: Tao C
Year: 2022
Journal: Development
Title: Chondroitin sulfate enhances the barrier function of basement membrane assembled by heparan sulfate.
Volume: 149
Issue: 12
Publication
First Author: Murphy DJ
Year: 2008
Journal: Cancer Cell
Title: Distinct thresholds govern Myc's biological output in vivo.
Volume: 14
Issue: 6
Pages: 447-57
Publication  
First Author: Panni RZ
Year: 2019
Journal: Sci Transl Med
Title: Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies.
Volume: 11
Issue: 499
Publication
First Author: Sachdeva M
Year: 2015
Journal: Cancer Lett
Title: Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182.
Volume: 369
Issue: 1
Pages: 202-11
Publication
First Author: Blaas L
Year: 2016
Journal: Nat Cell Biol
Title: Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours.
Volume: 18
Issue: 12
Pages: 1346-1356
Publication
First Author: Hegde S
Year: 2020
Journal: Cancer Cell
Title: Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer.
Volume: 37
Issue: 3
Pages: 289-307.e9
Publication      
First Author: Yang A
Year: 2018
Journal: Cancer Discov
Title: Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms.
Publication  
First Author: Nakazawa MS
Year: 2016
Journal: Nat Commun
Title: Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth.
Volume: 7
Pages: 10539
Publication
First Author: Nitzki F
Year: 2016
Journal: Oncogene
Title: Hedgehog/Patched-associated rhabdomyosarcoma formation from delta1-expressing mesodermal cells.
Volume: 35
Issue: 22
Pages: 2923-31
Publication
First Author: Hadji A
Year: 2014
Journal: Cell Rep
Title: Death induced by CD95 or CD95 ligand elimination.
Volume: 7
Issue: 1
Pages: 208-22
Publication
First Author: Norris AM
Year: 2013
Journal: Oncogene
Title: AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.
Volume: 32
Issue: 33
Pages: 3867-76
Publication
First Author: Wang P
Year: 2021
Journal: Adv Sci (Weinh)
Title: IL-36γ and IL-36Ra Reciprocally Regulate NSCLC Progression by Modulating GSH Homeostasis and Oxidative Stress-Induced Cell Death.
Volume: 8
Issue: 19
Pages: e2101501
Publication
First Author: Mullany LK
Year: 2014
Journal: Mol Endocrinol
Title: Tumor repressor protein 53 and steroid hormones provide a new paradigm for ovarian cancer metastases.
Volume: 28
Issue: 1
Pages: 127-37
Publication
First Author: Walter DM
Year: 2017
Journal: Cancer Res
Title: Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma.
Volume: 77
Issue: 7
Pages: 1719-1729
Publication
First Author: Lau AN
Year: 2014
Journal: EMBO J
Title: Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis.
Volume: 33
Issue: 5
Pages: 468-81
Publication
First Author: Zhang Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor Etv5 is essential for the maintenance of alveolar type II cells.
Volume: 114
Issue: 15
Pages: 3903-3908
Publication
First Author: Wang G
Year: 2018
Journal: Nat Med
Title: Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle.
Volume: 24
Issue: 6
Pages: 770-781
Publication
First Author: Park J
Year: 2024
Journal: Nature
Title: SMYD5 methylation of rpL40 links ribosomal output to gastric cancer.
Volume: 632
Issue: 8025
Pages: 656-663
Publication
First Author: Saloman JL
Year: 2018
Journal: Pancreas
Title: Systemic Depletion of Nerve Growth Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma.
Volume: 47
Issue: 7
Pages: 856-863
Publication
First Author: Gopinathan A
Year: 2015
Journal: Dis Model Mech
Title: GEMMs as preclinical models for testing pancreatic cancer therapies.
Volume: 8
Issue: 10
Pages: 1185-200
Publication
First Author: Mohseni M
Year: 2014
Journal: Nat Cell Biol
Title: A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway.
Volume: 16
Issue: 1
Pages: 108-17
Publication
First Author: Bassères DS
Year: 2010
Journal: Cancer Res
Title: Requirement of the NF-kappaB subunit p65/RelA for K-Ras-induced lung tumorigenesis.
Volume: 70
Issue: 9
Pages: 3537-46
Publication
First Author: White AC
Year: 2014
Journal: Nat Cell Biol
Title: Stem cell quiescence acts as a tumour suppressor in squamous tumours.
Volume: 16
Issue: 1
Pages: 99-107
Publication
First Author: Alderton GK
Year: 2014
Journal: Nat Rev Cancer
Title: Microenvironment: An exercise in restraint.
Volume: 14
Issue: 7
Pages: 449
Publication
First Author: Best SA
Year: 2022
Journal: Cell Metab
Title: Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer.
Volume: 34
Issue: 6
Pages: 874-887.e6
Publication
First Author: Ferguson LP
Year: 2023
Journal: Nat Commun
Title: Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma.
Volume: 14
Issue: 1
Pages: 292
Publication
First Author: Mazur PK
Year: 2015
Journal: Nat Med
Title: Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
Volume: 21
Issue: 10
Pages: 1163-71
Publication
First Author: Zhang M
Year: 2020
Journal: Nat Commun
Title: CCL7 recruits cDC1 to promote antitumor immunity and facilitate checkpoint immunotherapy to non-small cell lung cancer.
Volume: 11
Issue: 1
Pages: 6119
Publication
First Author: Nolan-Stevaux O
Year: 2009
Journal: Genes Dev
Title: GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.
Volume: 23
Issue: 1
Pages: 24-36
Publication
First Author: Kim KB
Year: 2022
Journal: Sci Adv
Title: KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer.
Volume: 8
Issue: 7
Pages: eabl4618
Publication
First Author: Walter DM
Year: 2019
Journal: Nature
Title: RB constrains lineage fidelity and multiple stages of tumour progression and metastasis.
Volume: 569
Issue: 7756
Pages: 423-427
Publication
First Author: Kabacaoğlu D
Year: 2021
Journal: Gastroenterology
Title: A Pancreas-Specific Ptf1a-Driven Cre Mouse Line Causes Paternally Transmitted Germline Recombination.
Volume: 161
Issue: 5
Pages: 1695-1697.e4
Publication
First Author: Cruz-Gil S
Year: 2019
Journal: PLoS One
Title: A more physiological approach to lipid metabolism alterations in cancer: CRC-like organoids assessment.
Volume: 14
Issue: 7
Pages: e0219944
Publication
First Author: Eichner LJ
Year: 2019
Journal: Cell Metab
Title: Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models.
Volume: 29
Issue: 2
Pages: 285-302.e7
Publication
First Author: Meyer MA
Year: 2018
Journal: Nat Commun
Title: Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance.
Volume: 9
Issue: 1
Pages: 1250
Publication
First Author: Daikoku T
Year: 2006
Journal: Cancer Res
Title: Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer.
Volume: 66
Issue: 5
Pages: 2527-31
Publication
First Author: Yin J
Year: 2018
Journal: Nat Commun
Title: Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy.
Volume: 9
Issue: 1
Pages: 1752
Publication
First Author: Park JH
Year: 2024
Journal: Nat Commun
Title: Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression.
Volume: 15
Issue: 1
Pages: 4099
Publication
First Author: DeVito NC
Year: 2021
Journal: Cell Rep
Title: Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy.
Volume: 35
Issue: 5
Pages: 109071
Publication
First Author: Papagiannakopoulos T
Year: 2016
Journal: Cell Metab
Title: Circadian Rhythm Disruption Promotes Lung Tumorigenesis.
Volume: 24
Issue: 2
Pages: 324-31
Publication
First Author: Rogers ZN
Year: 2018
Journal: Nat Genet
Title: Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice.
Volume: 50
Issue: 4
Pages: 483-486
Publication
First Author: Sempere LF
Year: 2011
Journal: Cancer Biol Ther
Title: A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells.
Volume: 12
Issue: 3
Pages: 198-207
Publication
First Author: Serresi M
Year: 2016
Journal: Cancer Cell
Title: Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer.
Volume: 29
Issue: 1
Pages: 17-31
Publication
First Author: Chuang CH
Year: 2017
Journal: Nat Med
Title: Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis.
Volume: 23
Issue: 3
Pages: 291-300
Publication
First Author: Suzuki Y
Year: 2024
Journal: Sci Rep
Title: Activation of STING in pancreatic cancer-associated fibroblasts exerts an antitumor effect by enhancing tumor immunity.
Volume: 14
Issue: 1
Pages: 17071
Publication
First Author: Welcker D
Year: 2018
Journal: Oncogene
Title: AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer.
Volume: 37
Issue: 11
Pages: 1503-1518
Publication    
First Author: Contat C
Year: 2020
Journal: Elife
Title: Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth.
Volume: 9
Publication
First Author: Carugo A
Year: 2019
Journal: Cancer Cell
Title: p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Volume: 35
Issue: 2
Pages: 204-220.e9
Publication
First Author: Lee P
Year: 2020
Journal: Nat Commun
Title: Targeting glutamine metabolism slows soft tissue sarcoma growth.
Volume: 11
Issue: 1
Pages: 498
Publication
First Author: Li A
Year: 2019
Journal: Cell Rep
Title: IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development.
Volume: 29
Issue: 10
Pages: 2998-3008.e8
Publication
First Author: Mazur PK
Year: 2014
Journal: Nature
Title: SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
Volume: 510
Issue: 7504
Pages: 283-7
Publication
First Author: Messal HA
Year: 2019
Journal: Nature
Title: Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
Volume: 566
Issue: 7742
Pages: 126-130
Publication
First Author: Lee MC
Year: 2023
Journal: Cell Rep
Title: A multiplexed in vivo approach to identify driver genes in small cell lung cancer.
Volume: 42
Issue: 1
Pages: 111990
Publication  
First Author: Cammareri P
Year: 2016
Journal: Nat Commun
Title: Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma.
Volume: 7
Pages: 12493
Publication
First Author: DeBlasi JM
Year: 2023
Journal: Cancer Res
Title: Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression.
Volume: 83
Issue: 12
Pages: 1953-1967
Publication
First Author: Cheung PF
Year: 2018
Journal: Cancer Res
Title: Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.
Volume: 78
Issue: 17
Pages: 4997-5010
Publication
First Author: Sato K
Year: 2020
Journal: PLoS One
Title: Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels.
Volume: 15
Issue: 7
Pages: e0235573
Publication  
First Author: Lubeseder-Martellato C
Year: 2017
Journal: EBioMedicine
Title: Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions.
Volume: 15
Pages: 90-99
Publication  
First Author: Debaugnies M
Year: 2018
Journal: EMBO Rep
Title: YAP and TAZ are essential for basal and squamous cell carcinoma initiation.
Volume: 19
Issue: 7
Publication
First Author: Yoon SJ
Year: 2023
Journal: Cancer Res
Title: Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.
Volume: 83
Issue: 9
Pages: 1426-1442
Publication
First Author: Li M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Targeting reactive nitrogen species suppresses hereditary pancreatic cancer.
Volume: 114
Issue: 27
Pages: 7106-7111
Publication
First Author: Fox RG
Year: 2016
Journal: Nature
Title: Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Volume: 534
Issue: 7607
Pages: 407-411
Publication
First Author: Cellurale C
Year: 2012
Journal: Cancer Res
Title: Role of JNK in mammary gland development and breast cancer.
Volume: 72
Issue: 2
Pages: 472-81
Publication
First Author: Best SA
Year: 2018
Journal: Cell Metab
Title: Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment.
Volume: 27
Issue: 4
Pages: 935-943.e4
Publication
First Author: Lytle NK
Year: 2019
Journal: Cell
Title: A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.
Volume: 177
Issue: 3
Pages: 572-586.e22
Publication
First Author: Iltzsche F
Year: 2017
Journal: Oncogene
Title: An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma.
Volume: 36
Issue: 1
Pages: 110-121
Publication
First Author: Ganesh K
Year: 2020
Journal: Nat Cancer
Title: L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer.
Volume: 1
Issue: 1
Pages: 28-45
Publication  
First Author: Floyd W
Year: 2023
Journal: J Clin Invest
Title: Atrx deletion impairs CGAS/STING signaling and increases sarcoma response to radiation and oncolytic herpesvirus.
Volume: 133
Issue: 13
Publication
First Author: Rhim AD
Year: 2012
Journal: Cell
Title: EMT and dissemination precede pancreatic tumor formation.
Volume: 148
Issue: 1-2
Pages: 349-61
Publication
First Author: Mazur PK
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma.
Volume: 107
Issue: 30
Pages: 13438-43
Publication
First Author: Yu Y
Year: 2018
Journal: Cancer Cell
Title: Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.
Volume: 33
Issue: 2
Pages: 322-336.e8