Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
•
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•
•
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
•
•
•
•
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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•
•
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•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
•
•
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
•
•
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•
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
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•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Allele |
Name: |
transgene insertion 73, Lawrence SB Goldstein |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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•
•
•
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•
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Allele |
Name: |
transgene insertion 90, Lawrence SB Goldstein |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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•
•
•
•
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Transgene |
Type: |
transgene |
Organism: |
mouse, laboratory |
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Transgene |
Type: |
transgene |
Organism: |
mouse, laboratory |
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Strain |
Attribute String: |
transgenic, congenic |
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Publication |
First Author: |
Goldstein LSB |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Generation of a low-expression kinesin light chain 1 transgene |
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Strain |
Attribute String: |
transgenic, congenic |
|
•
•
•
•
•
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Publication |
First Author: |
Goldstein LSB |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Generation of a high-expression kinesin light chain 1 transgene |
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•
•
•
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•
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Allele |
Name: |
kinesin light chain 1; targeted mutation 1, Lawrence S B Goldstein |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
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•
•
•
•
•
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Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
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Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
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Genotype |
Symbol: |
Klc1/Klc1 |
Background: |
either: (involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Genotype |
Symbol: |
Klc1/Klc1 |
Background: |
B6.129-Klc1 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Klc1/Klc1 |
Background: |
involves: 129S1/Sv * 129X1/SvJ |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
•
•
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Protein Domain |
Type: |
Domain |
Description: |
This entry represents the cytoplasmic C-terminal domain of calsyntenin (CLSTN) proteins 1, 2 and 3 (also known as alcadein-alpha, beta and gamma). These are postsynaptic Ca2-binding proteins, evolutionarily conserved type I membrane proteins. CLSTN (also known as Alc) forms a tripartite complex with APP (amyloid beta-protein precursor) and X11L (a neuron-specific adaptor protein) in brain; this complex stabilizes both APP and CLSTN proteins metabolically. Deficiencies in the X11L-mediated interaction between CLSTN and APP and/or CTFbeta enhances the production of amyloid beta-protein and have been linked to the development or progression of Alzheimer's disease []. Moreover, CLSTN1 strongly associates with kinesin-1 light chains (KLC1) and acts as a cargo that regulates kinesin-1 function. It may affect the transport of APP-containing vesicles by kinesin-1 []. This domain includes the WD motifs required for KLC1 interaction (although one WD motif is sufficient), and the NP motif []. |
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•
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Publication |
First Author: |
Araki Y |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism. |
Volume: |
278 |
Issue: |
49 |
Pages: |
49448-58 |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
357
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Aoyama T |
Year: |
2009 |
Journal: |
J Cell Sci |
Title: |
Cayman ataxia protein caytaxin is transported by kinesin along neurites through binding to kinesin light chains. |
Volume: |
122 |
Issue: |
Pt 22 |
Pages: |
4177-85 |
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•
•
•
•
•
|
Publication |
First Author: |
Morihara T |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-β accumulation modifier. |
Volume: |
111 |
Issue: |
7 |
Pages: |
2638-43 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Klc1/Klc1<+> Tg(APP695)3Dbo/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
956
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
966
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
979
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
919
 |
Fragment?: |
false |
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•
•
•
•
|