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Search results 4601 to 4700 out of 7122 for App

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Type Details Score
GXD Expression
Probe: MGI:3821218
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421764
Age: embryonic day 14.5
Image: MY255; Specimen C1481
Note: Expression was weak in whisker follicle.
Specimen Label: MY255; Specimen C1481
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6860346
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860350
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860346
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860350
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6860346
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860350
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860346
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3817528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860350
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
Publication    
First Author: Choi DK
Year: 2000
Journal: GenBank Submission
Title: Mus musculus aspartyl protease 1 mRNA, complete cds
Pages: AF216310
Publication
First Author: Abud EM
Year: 2017
Journal: Neuron
Title: iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.
Volume: 94
Issue: 2
Pages: 278-293.e9
Publication
First Author: Badimon A
Year: 2020
Journal: Nature
Title: Negative feedback control of neuronal activity by microglia.
Volume: 586
Issue: 7829
Pages: 417-423
Publication
First Author: Zhang H
Year: 2020
Journal: J Neurosci
Title: A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance.
Volume: 40
Issue: 28
Pages: 5347-5361
Publication
First Author: Hasselmann J
Year: 2019
Journal: Neuron
Title: Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo.
Volume: 103
Issue: 6
Pages: 1016-1033.e10
Publication  
First Author: Gulbranson DR
Year: 2021
Journal: eNeuro
Title: Phenotypic Differences between the Alzheimer's Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice.
Volume: 8
Issue: 3
Publication
First Author: Crowe SE
Year: 2013
Journal: J Comp Neurol
Title: In vivo characterization of a bigenic fluorescent mouse model of Alzheimer's disease with neurodegeneration.
Volume: 521
Issue: 10
Pages: Spc1
Publication
First Author: McQuade A
Year: 2020
Journal: Nat Commun
Title: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 5370
Publication
First Author: Brandao W
Year: 2025
Journal: Sci Transl Med
Title: Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy.
Volume: 17
Issue: 781
Pages: eadk3690
Publication
First Author: Da Mesquita S
Year: 2021
Journal: Nature
Title: Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy.
Volume: 593
Issue: 7858
Pages: 255-260
Publication
First Author: Levine S
Year: 2009
Journal: Exp Mol Pathol
Title: Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease.
Volume: 86
Issue: 1
Pages: 18-22
Publication
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
Volume: 21
Issue: 23
Pages: 5131-46
Publication
First Author: Plagg B
Year: 2015
Journal: Biogerontology
Title: Platelet dysfunction in hypercholesterolemia mice, two Alzheimer's disease mouse models and in human patients with Alzheimer's disease.
Volume: 16
Issue: 4
Pages: 543-58
Publication
First Author: Plagg B
Year: 2015
Journal: Curr Alzheimer Res
Title: Increased Acetylation of Histone H4 at Lysine 12 (H4K12) in Monocytes of Transgenic Alzheimer's Mice and in Human Patients.
Volume: 12
Issue: 8
Pages: 752-60
Publication  
First Author: Xu G
Year: 2022
Journal: Biomolecules
Title: Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer's Disease.
Volume: 12
Issue: 7
Publication  
First Author: William CM
Year: 2021
Journal: Neurobiol Dis
Title: Impairment of visual cortical plasticity by amyloid-beta species.
Volume: 154
Pages: 105344
Publication
First Author: Meyer-Luehmann M
Year: 2006
Journal: Science
Title: Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.
Volume: 313
Issue: 5794
Pages: 1781-4
Publication
First Author: Zhou XW
Year: 2008
Journal: FEBS Lett
Title: Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Abeta overproduction.
Volume: 582
Issue: 2
Pages: 159-64
Publication
First Author: Cho HS
Year: 1995
Journal: Comp Biochem Physiol B Biochem Mol Biol
Title: Age-related changes of mRNA expression of amyloid precursor protein in the brain of senescence-accelerated mouse.
Volume: 112
Issue: 2
Pages: 399-404
Publication
First Author: Chrast R
Year: 1995
Journal: Genomics
Title: Mapping of the human transcription factor GABPA (E4TF1-60) gene to chromosome 21.
Volume: 28
Issue: 1
Pages: 119-22
Publication
First Author: McLoughlin DM
Year: 1996
Journal: FEBS Lett
Title: The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system.
Volume: 397
Issue: 2-3
Pages: 197-200
Publication
First Author: Kimura A
Year: 2015
Journal: FEBS Lett
Title: Stabilization of intracellular trafficking and metabolism of amyloid β-protein precursor and Alcadein β by apolipoprotein E.
Volume: 589
Issue: 18
Pages: 2394-400
Publication
First Author: Iijima K
Year: 2000
Journal: J Neurochem
Title: Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.
Volume: 75
Issue: 3
Pages: 1085-91
Protein
Organism: Mus musculus/domesticus
Length: 956  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 966  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 979  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 919  
Fragment?: false
Publication
First Author: Sherman MA
Year: 2016
Journal: J Neurosci
Title: Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.
Volume: 36
Issue: 37
Pages: 9647-58
Publication  
First Author: Lauritzen I
Year: 2019
Journal: Transl Neurodegener
Title: Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models.
Volume: 8
Pages: 35
Publication
First Author: Sanotra MR
Year: 2023
Journal: Alzheimers Res Ther
Title: Acrolein adducts and responding autoantibodies correlate with metabolic disturbance in Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 115
Publication  
First Author: Imamura T
Year: 2020
Journal: Neurobiol Dis
Title: Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.
Volume: 137
Pages: 104739
Publication
First Author: El Khoury J
Year: 2007
Journal: Nat Med
Title: Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.
Volume: 13
Issue: 4
Pages: 432-8
Publication
First Author: Lubitz I
Year: 2014
Journal: Neurobiol Aging
Title: Non-viability of crossing the Alzheimer mouse model Tg2576 with the type 2 diabetes mouse model ob/ob.
Volume: 35
Issue: 7
Pages: e19-20
Publication
First Author: Firuzi O
Year: 2008
Journal: FASEB J
Title: 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease.
Volume: 22
Issue: 4
Pages: 1169-78
Publication
First Author: Bates KA
Year: 2002
Journal: Neuroscience
Title: Chronic gliosis triggers Alzheimer's disease-like processing of amyloid precursor protein.
Volume: 113
Issue: 4
Pages: 785-96
Publication
First Author: Holtzman DM
Year: 2000
Journal: Ann Neurol
Title: Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.
Volume: 47
Issue: 6
Pages: 739-47
Publication
First Author: Colton CA
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease.
Volume: 103
Issue: 34
Pages: 12867-72
Publication
First Author: Li T
Year: 2007
Journal: J Biol Chem
Title: Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase.
Volume: 282
Issue: 44
Pages: 32264-73
Publication
First Author: Park L
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein.
Volume: 105
Issue: 4
Pages: 1347-52
Publication
First Author: Park L
Year: 2005
Journal: J Neurosci
Title: NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.
Volume: 25
Issue: 7
Pages: 1769-77
Publication
First Author: Jeong YH
Year: 2011
Journal: J Neurochem
Title: Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer's disease model.
Volume: 119
Issue: 6
Pages: 1282-93
Publication
First Author: Friedlich AL
Year: 2004
Journal: J Neurosci
Title: Neuronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease.
Volume: 24
Issue: 13
Pages: 3453-9
Publication  
First Author: Vilella A
Year: 2023
Journal: Front Neurosci
Title: Evidence for a protective effect of the loss of α4-containing nicotinic acetylcholine receptors on Aβ-related neuropathology in Tg2576 mice.
Volume: 17
Pages: 1097857
Publication
First Author: Czirr E
Year: 2017
Journal: J Exp Med
Title: Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.
Volume: 214
Issue: 4
Pages: 1081-1092
Publication
First Author: Gong B
Year: 2013
Journal: Mol Immunol
Title: IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway.
Volume: 56
Issue: 4
Pages: 619-29
Publication
First Author: Tesseur I
Year: 2000
Journal: Am J Pathol
Title: Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice.
Volume: 156
Issue: 3
Pages: 951-64
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Hartman RE
Year: 2005
Journal: J Neurosci
Title: Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease.
Volume: 25
Issue: 26
Pages: 6213-20
Publication
First Author: Giacchino J
Year: 2000
Journal: Brain Res
Title: In vivo synaptic transmission in young and aged amyloid precursor protein transgenic mice.
Volume: 876
Issue: 1-2
Pages: 185-90
Publication
First Author: Winsky-Sommerer R
Year: 2004
Journal: Brain Res
Title: Overexpression of the human beta-amyloid precursor protein downregulates cortistatin mRNA in PDAPP mice.
Volume: 1023
Issue: 1
Pages: 157-62
Publication
First Author: Wu CC
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: digital morphometric analyses.
Volume: 101
Issue: 18
Pages: 7141-6
Publication
First Author: Weir HJ
Year: 2012
Journal: PLoS One
Title: CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease.
Volume: 7
Issue: 11
Pages: e48225
Publication
First Author: Yoshida T
Year: 2005
Journal: J Clin Invest
Title: The potential role of amyloid beta in the pathogenesis of age-related macular degeneration.
Volume: 115
Issue: 10
Pages: 2793-800
Publication
First Author: Lombardo JA
Year: 2003
Journal: J Neurosci
Title: Amyloid-beta antibody treatment leads to rapid normalization of plaque-induced neuritic alterations.
Volume: 23
Issue: 34
Pages: 10879-83
Publication
First Author: Becker M
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Stimulation of endogenous neurogenesis by anti-EFRH immunization in a transgenic mouse model of Alzheimer's disease.
Volume: 104
Issue: 5
Pages: 1691-6
Publication
First Author: Bussière T
Year: 2004
Journal: Am J Pathol
Title: Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance.
Volume: 165
Issue: 3
Pages: 987-95
Publication
First Author: Bales KR
Year: 2006
Journal: J Clin Invest
Title: Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody.
Volume: 116
Issue: 3
Pages: 825-32
Publication
First Author: Kuc KA
Year: 2006
Journal: Genes Brain Behav
Title: Holeboard discrimination learning in mice.
Volume: 5
Issue: 4
Pages: 355-63
Publication
First Author: German DC
Year: 2005
Journal: J Comp Neurol
Title: The PDAPP mouse model of Alzheimer's disease: locus coeruleus neuronal shrinkage.
Volume: 492
Issue: 4
Pages: 469-76
Publication
First Author: Dodart JC
Year: 1999
Journal: Behav Neurosci
Title: Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein.
Volume: 113
Issue: 5
Pages: 982-90
Publication
First Author: Pierce A
Year: 2013
Journal: J Neurochem
Title: Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease.
Volume: 124
Issue: 6
Pages: 880-93
Publication
First Author: Valla J
Year: 2006
Journal: Brain Res
Title: Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice.
Volume: 1116
Issue: 1
Pages: 194-200
Publication
First Author: Chen G
Year: 2007
Journal: J Neurosci
Title: Active beta-amyloid immunization restores spatial learning in PDAPP mice displaying very low levels of beta-amyloid.
Volume: 27
Issue: 10
Pages: 2654-62
Publication
First Author: Nilsson LN
Year: 2001
Journal: J Neurosci
Title: Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease.
Volume: 21
Issue: 5
Pages: 1444-51
Publication
First Author: Sánchez-Alavez M
Year: 2002
Journal: Neurosci Lett
Title: Loss of medial septal modulation of dentate gyrus physiology in young mice overexpressing human beta-amyloid precursor protein.
Volume: 330
Issue: 1
Pages: 45-8
Publication
First Author: Spires-Jones TL
Year: 2009
Journal: Neurobiol Dis
Title: Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease.
Volume: 33
Issue: 2
Pages: 213-20
Publication
First Author: Selwood SP
Year: 2009
Journal: Neurobiol Aging
Title: Gene expression profile of the PDAPP mouse model for Alzheimer's disease with and without Apolipoprotein E.
Volume: 30
Issue: 4
Pages: 574-90
Publication
First Author: Zerbinatti CV
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein.
Volume: 101
Issue: 4
Pages: 1075-80
Publication
First Author: German DC
Year: 2003
Journal: J Comp Neurol
Title: Cholinergic neuropathology in a mouse model of Alzheimer's disease.
Volume: 462
Issue: 4
Pages: 371-81
Publication
First Author: Brendza RP
Year: 2003
Journal: J Comp Neurol
Title: PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures.
Volume: 456
Issue: 4
Pages: 375-83
Publication
First Author: Brody DL
Year: 2006
Journal: Exp Neurol
Title: Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury.
Volume: 197
Issue: 2
Pages: 330-40
Publication
First Author: Rossi D
Year: 2005
Journal: J Biol Chem
Title: Defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease.
Volume: 280
Issue: 51
Pages: 42088-96
Publication
First Author: Gerlai R
Year: 2002
Journal: Behav Brain Res
Title: Behavioral impairment of APP(V717F) mice in fear conditioning: is it only cognition?
Volume: 136
Issue: 2
Pages: 503-9
Publication
First Author: Masliah E
Year: 2001
Journal: J Neuropathol Exp Neurol
Title: Neurofibrillary pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.
Volume: 60
Issue: 4
Pages: 357-68
Publication
First Author: Reilly JF
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model.
Volume: 100
Issue: 8
Pages: 4837-42
Publication
First Author: Demattos RB
Year: 2012
Journal: Neuron
Title: A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice.
Volume: 76
Issue: 5
Pages: 908-20
Publication  
First Author: Xu L
Year: 2017
Journal: Neural Plast
Title: Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease.
Volume: 2017
Pages: 3270725
Publication
First Author: McIntire LB
Year: 2012
Journal: J Neurosci
Title: Reduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease.
Volume: 32
Issue: 44
Pages: 15271-6
Publication
First Author: Berman DE
Year: 2008
Journal: Nat Neurosci
Title: Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism.
Volume: 11
Issue: 5
Pages: 547-54
Strain
Attribute String: transgenic, mutant strain, coisogenic
Strain
Attribute String: mutant strain, transgenic, coisogenic
Publication  
First Author: Zamarbide M
Year: 2022
Journal: Int J Mol Sci
Title: Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.
Volume: 23
Issue: 7
Publication
First Author: Morawski M
Year: 2010
Journal: Neurobiol Aging
Title: Perineuronal nets are largely unaffected in Alzheimer model Tg2576 mice.
Volume: 31
Issue: 7
Pages: 1254-6
Publication
First Author: Savage MJ
Year: 2002
Journal: J Neurosci
Title: Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition.
Volume: 22
Issue: 9
Pages: 3376-85
Publication
First Author: Zhao Z
Year: 2015
Journal: Nat Neurosci
Title: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
Volume: 18
Issue: 7
Pages: 978-87
Publication  
First Author: Nagy D
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Developmental synaptic regulator, TWEAK/Fn14 signaling, is a determinant of synaptic function in models of stroke and neurodegeneration.
Volume: 118
Issue: 6
Publication
First Author: Serrano J
Year: 2010
Journal: Oncogene
Title: High sensitivity to carcinogens in the brain of a mouse model of Alzheimer's disease.
Volume: 29
Issue: 15
Pages: 2165-71
Publication
First Author: de Diego AM
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Smaller quantal size and faster kinetics of single exocytotic events in chromaffin cells from the APP/PS1 mouse model of Alzheimer's disease.
Volume: 428
Issue: 4
Pages: 482-6
Publication  
First Author: Weng Y
Year: 2021
Journal: Redox Biol
Title: Trem2 mediated Syk-dependent ROS amplification is essential for osteoclastogenesis in periodontitis microenvironment.
Volume: 40
Pages: 101849
Publication
First Author: Lordén G
Year: 2022
Journal: Nat Commun
Title: Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model.
Volume: 13
Issue: 1
Pages: 7200
Publication
First Author: Nishida Y
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Deletion of vitamin E enhances phenotype of Alzheimer disease model mouse.
Volume: 350
Issue: 3
Pages: 530-6
Publication
First Author: Kanekiyo T
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid.
Volume: 104
Issue: 15
Pages: 6412-7
Publication  
First Author: Kam K
Year: 2016
Journal: Sci Rep
Title: Interictal spikes during sleep are an early defect in the Tg2576 mouse model of β-amyloid neuropathology.
Volume: 6
Pages: 20119
Publication
First Author: Lee JK
Year: 2012
Journal: Stem Cells
Title: Soluble CCL5 derived from bone marrow-derived mesenchymal stem cells and activated by amyloid β ameliorates Alzheimer's disease in mice by recruiting bone marrow-induced microglia immune responses.
Volume: 30
Issue: 7
Pages: 1544-55
Strain
Attribute String: congenic, mutant strain, transgenic