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Search results 101 to 132 out of 132 for Vps13d

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Type Details Score
Publication
30741634 | -
   
First Author: Yeshaw WM
Year: 2019
Journal: Elife
Title: Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility.
Volume: 8
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Publication
30709847 | -
 
First Author: Muñoz-Braceras S
Year: 2019
Journal: Dis Model Mech
Title: VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation.
Volume: 12
Issue: 2
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Publication
34216812 | -
First Author: Leonzino M
Year: 2021
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Insights into VPS13 properties and function reveal a new mechanism of eukaryotic lipid transport.
Volume: 1866
Issue: 10
Pages: 159003
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Protein
B1ART1
Organism: Mus musculus/domesticus
Length: 4359  
Fragment?: false
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Protein
B1ART2
Organism: Mus musculus/domesticus
Length: 4390  
Fragment?: false
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Protein
A1ILH1
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
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Protein
A1ILG9
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: true
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Protein
Q3TN78
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Protein
A1ILH0
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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Protein
F6XI52
Organism: Mus musculus/domesticus
Length: 1078  
Fragment?: true
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Protein
A1ILH6
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
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Protein
A0A286YCT3
Organism: Mus musculus/domesticus
Length: 2339  
Fragment?: false
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Protein
Q8C9M0
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
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Protein
A0A2I3BPN3
Organism: Mus musculus/domesticus
Length: 46  
Fragment?: true
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Publication
23444357 | -
First Author: Koizumi K
Year: 2013
Journal: Development
Title: Identification of SHRUBBY, a SHORT-ROOT and SCARECROW interacting protein that controls root growth and radial patterning.
Volume: 140
Issue: 6
Pages: 1292-300
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Publication
28122955 | -
First Author: De M
Year: 2017
Journal: J Cell Biol
Title: The Vps13p-Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion.
Volume: 216
Issue: 2
Pages: 425-439
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Protein Domain
IPR009543 | VPS13_VAB
Type: Domain
Description: This entry represents the VPS13 adaptor binding (VAB) domain, previously known as SHR-BD, found in VPS13 []. These proteins interact with membrane-specific adaptor proteins such as Ypt35, Spo71 and the mitochondrial membrane protein Mcp1, to be recruited to different membranes. This domain interacts with Ypt35 which recruits VPS13 to endosomal and vacuolar membranes, and with Mcp1 to target VPS13 at mitochondria []. In plants, this domain is found to be the region which interacts with SHR or the SHORT-ROOT transcription factor, a regulator of root-growth and asymmetric cell division that separates ground tissue into endodermis and cortex. The plant protein containing the SHR-BD is named SHRUBBY or SHBY () [].This domain likely adopts an elongated structure consisting of β-sheets. It has been described as a β-propeller/WD40-like structure [, ], however, based on structural models, it does not seem to have that 3D arrangement.VPS13 proteins have been implicated in processes including vesicle fusion, autophagy, and actin regulation. They bind phospholipids and act as channels that mediate the transfer of lipids between membranes at organelle contact sites [, , ]. It has been proposed that members of this entry have the capacity to bind and likely transfer tens of glycerolipids at once. Yeast VPS13 acts at multiple cellular sites, namely the interface between mitochondria and the vacuole, on endosomes, on the nuclear-vacuole junction and the vacuole, depending on the carbon source and metabolic state. Most evidence showed that mammalian VPS13A, VPS13C and VPS13D localize at contacts between the ER and other organelles, i.e. VPS13A and VPS13D bridge the ER to mitochondria, VPS13C bridges the ER to late endosomes and lysosomes and VPS13B may localize to endosome-endosome contacts [, , ]. Mutations in human VPS13 proteins (VPS13A-D) cause different diseases such as Chorea-acanthocytosis, Cohen syndrome, Parkinson's disease, and spastic ataxia, respectively which suggests they have different functions [, ].
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Protein
Q80TY5
Organism: Mus musculus/domesticus
Length: 3993  
Fragment?: false
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Protein
A0A1L1SUY8
Organism: Mus musculus/domesticus
Length: 771  
Fragment?: false
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Protein
Q8BX70
Organism: Mus musculus/domesticus
Length: 3748  
Fragment?: false
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Protein
Q5H8C4
Organism: Mus musculus/domesticus
Length: 3166  
Fragment?: false
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Protein
A1ILG8
Organism: Mus musculus/domesticus
Length: 3748  
Fragment?: false
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Publication
34830155 | -
 
First Author: Kolakowski D
Year: 2021
Journal: Int J Mol Sci
Title: The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus.
Volume: 22
Issue: 22
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Publication
30093493 | -
First Author: Kumar N
Year: 2018
Journal: J Cell Biol
Title: VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.
Volume: 217
Issue: 10
Pages: 3625-3639
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Protein
V9GX23
Organism: Mus musculus/domesticus
Length: 3211  
Fragment?: true
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Protein
Q6A066
Organism: Mus musculus/domesticus
Length: 1918  
Fragment?: true
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Protein
Q6P4T0
Organism: Mus musculus/domesticus
Length: 1914  
Fragment?: false
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Protein
Q80XK6
Organism: Mus musculus/domesticus
Length: 2075  
Fragment?: false
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Protein
Q8CDS8
Organism: Mus musculus/domesticus
Length: 921  
Fragment?: false
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Protein
A0A286YCC3
Organism: Mus musculus/domesticus
Length: 857  
Fragment?: true
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Protein
Q6P6M9
Organism: Mus musculus/domesticus
Length: 1186  
Fragment?: true
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Protein
A0A1L1SS63
Organism: Mus musculus/domesticus
Length: 757  
Fragment?: true
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