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Search results 1501 to 1597 out of 1597 for Fras1

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Type Details Score
Allele
Grip1<eb> | MGI:1856852
 
Name: glutamate receptor interacting protein 1; eye blebs
Allele Type: Spontaneous
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Allele
Fras1<bl> | MGI:1856691
 
Name: Fraser extracellular matrix complex subunit 1; blebbed
Allele Type: Radiation induced
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Genotype
Genotype
Symbol: Fras1/Fras1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grip1/Grip1
Background: B6.129-Grip1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grip1/Grip1
Background: involves: ATEB/Le * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fras1/Fras1
Background: involves: 129S1/Sv * 129X1/SvJ * NMRI
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fras1/Fras1
Background: involves: C57BL/6JAnu
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0090001 | Fraser syndrome
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Genotype
Genotype
Symbol: Fras1/Fras1
Background: involves: C57BL/6J * FVB/NJ
Zygosity: hm
Has Mutant Allele: true
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Publication
15878328 | J:99700
First Author: Kiyozumi D
Year: 2005
Journal: Exp Cell Res
Title: Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.
Volume: 306
Issue: 1
Pages: 9-23
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Publication
26234751 | J:223062
First Author: Palmer K
Year: 2016
Journal: Dev Biol
Title: Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.
Volume: 415
Issue: 2
Pages: 216-227
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Publication
33875569 | J:313559
     
First Author: Lipp SN
Year: 2021
Journal: J Am Soc Nephrol
Title: 3D Mapping Reveals a Complex and Transient Interstitial Matrix During Murine Kidney Development.
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Genotype
Genotype
Symbol: Fras1/Fras1
Background: involves: 101/H * C3H/HeH
Zygosity: hm
Has Mutant Allele: true
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Protein Coding Gene
MGI:1921303 | Grip1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21289216 | J:191040
First Author: Ola R
Year: 2011
Journal: J Am Soc Nephrol
Title: The GDNF target Vsnl1 marks the ureteric tip.
Volume: 22
Issue: 2
Pages: 274-84
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Publication
36335435 | J:335095
First Author: Lipp SN
Year: 2023
Journal: Dev Dyn
Title: FOXD1 is required for 3D patterning of the kidney interstitial matrix.
Volume: 252
Issue: 4
Pages: 463-482
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Publication
30567998 | J:272608
First Author: Cohen I
Year: 2019
Journal: Genes Dev
Title: PRC1 preserves epidermal tissue integrity independently of PRC2.
Volume: 33
Issue: 1-2
Pages: 55-60
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Protein
F7D5I3
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: true
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Publication
12955145 | J:85113
First Author: Kile BT
Year: 2003
Journal: Nature
Title: Functional genetic analysis of mouse chromosome 11.
Volume: 425
Issue: 6953
Pages: 81-6
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Publication
25245104 | J:256264
First Author: Diman NY
Year: 2014
Journal: Circ Res
Title: Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis.
Volume: 115
Issue: 10
Pages: 834-44
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Protein
Q9ET73
Organism: Mus musculus/domesticus
Length: 35  
Fragment?: true
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Protein
S4R2V4
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: true
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Protein
Q9R074
Organism: Mus musculus/domesticus
Length: 50  
Fragment?: true
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Protein
Q9R073
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: true
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Protein
Q9ET70
Organism: Mus musculus/domesticus
Length: 43  
Fragment?: true
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Protein
Q9R072
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: true
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Protein Domain
IPR038081 | CalX-like_sf
Type: Homologous_superfamily
Description: The calx-beta motif is present as a tandem repeat in the cytoplasmic domains of Calx Na-Ca exchangers, which are used to expel calcium from cells. This motif overlaps domains used for calcium binding and regulation. The calx-beta motif is also present in the cytoplasmic tail of mammalian integrin-beta4, which mediates the bi-directional transfer of signals across the plasma membrane, as well as in some cyanobacterial proteins. This motif is also found in Fras1/Frem family of extracellular proteins (extracellular matrix organizing protein FRAS1 and FRAS1-related extracellular matrix proteins FRAM1, 2 and 3) required for proper organogenesis during embryonic development and whose mutations lead to Fraser Syndrome, a rare congenital disorder characterised by multisystem malformation usually comprising abnormal brain formation, cryptophthalmos, syndactyly and renal defects []. This motif contains a series of β-strands and turns that form a self-contained β-sheet [, ].
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Protein Domain
IPR003644 | Calx_beta
Type: Domain
Description: The calx-beta motif is present as a tandem repeat in the cytoplasmic domains of Calx Na-Ca exchangers, which are used to expel calcium from cells. This motif overlaps domains used for calcium binding and regulation. The calx-beta motif is also present in the cytoplasmic tail of mammalian integrin-beta4, which mediates the bi-directional transfer of signals across the plasma membrane, as well as in some cyanobacterial proteins. This motif is also found in Fras1/Frem family of extracellular proteins (extracellular matrix organizing protein FRAS1 and FRAS1-related extracellular matrix proteins FRAM1, 2 and 3) required for proper organogenesis during embryonic development and whose mutations lead to Fraser Syndrome, a rare congenital disorder characterised by multisystem malformation usually comprising abnormal brain formation, cryptophthalmos, syndactyly and renal defects []. This motif contains a series of β-strands and turns that form a self-contained β-sheet [, ].
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Protein
F6X844
Organism: Mus musculus/domesticus
Length: 533  
Fragment?: true
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Protein
Q8R503
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: true
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Publication
9294196 | -
First Author: Schwarz EM
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Calx, a Na-Ca exchanger gene of Drosophila melanogaster.
Volume: 94
Issue: 19
Pages: 10249-54
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Publication
10390612 | -
First Author: Schwarz E
Year: 1999
Journal: Trends Biochem Sci
Title: The recently reported NIbeta domain is already known as the Calx-beta motif.
Volume: 24
Issue: 7
Pages: 260
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Publication
21182980 | -
First Author: Pavlakis E
Year: 2011
Journal: Int J Biochem Cell Biol
Title: The role of Fras1/Frem proteins in the structure and function of basement membrane.
Volume: 43
Issue: 4
Pages: 487-95
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Publication
25917818 | J:222308
First Author: Fairfield H
Year: 2015
Journal: Genome Res
Title: Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.
Volume: 25
Issue: 7
Pages: 948-57
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Publication
27856617 | J:237202
First Author: Fantauzzo KA
Year: 2016
Journal: Genes Dev
Title: PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.
Volume: 30
Issue: 21
Pages: 2443-2458
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Protein
D3YYF1
Organism: Mus musculus/domesticus
Length: 1218  
Fragment?: false
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Protein
Q8BPQ5
Organism: Mus musculus/domesticus
Length: 416  
Fragment?: false
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Protein
Q6NVD0
Organism: Mus musculus/domesticus
Length: 3160  
Fragment?: false
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Protein
Q5H8B9
Organism: Mus musculus/domesticus
Length: 2123  
Fragment?: false
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Protein
Q8K596
Organism: Mus musculus/domesticus
Length: 921  
Fragment?: false
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Protein
S4R2P9
Organism: Mus musculus/domesticus
Length: 928  
Fragment?: false
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Protein
Q9EPU8
Organism: Mus musculus/domesticus
Length: 595  
Fragment?: true
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Protein
Q6ZPY3
Organism: Mus musculus/domesticus
Length: 723  
Fragment?: true
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Protein
F8WHZ0
Organism: Mus musculus/domesticus
Length: 2127  
Fragment?: false
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Protein
Q8R505
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: true
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Protein
Q3UTP5
Organism: Mus musculus/domesticus
Length: 921  
Fragment?: false
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Protein
Q91ZS2
Organism: Mus musculus/domesticus
Length: 2780  
Fragment?: false
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Protein
E9PX50
Organism: Mus musculus/domesticus
Length: 927  
Fragment?: false
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Protein
Q8BXN1
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: true
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Protein
H6W0X2
Organism: Mus musculus/domesticus
Length: 1347  
Fragment?: true
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Protein
G5E8P3
Organism: Mus musculus/domesticus
Length: 2238  
Fragment?: false
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Protein
H6W0X1
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: true
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Publication
26952977 | J:235538
First Author: Tomann P
Year: 2016
Journal: Development
Title: Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.
Volume: 143
Issue: 9
Pages: 1512-22
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Publication
21795542 | J:174607
First Author: Lu CC
Year: 2011
Journal: J Neurosci
Title: Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly.
Volume: 31
Issue: 30
Pages: 10903-18
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Protein
Q684R7
Organism: Mus musculus/domesticus
Length: 2191  
Fragment?: false
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Protein
A2ADN1
Organism: Mus musculus/domesticus
Length: 2172  
Fragment?: false
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Protein
E9Q5Z7
Organism: Mus musculus/domesticus
Length: 2173  
Fragment?: false
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Protein
Q8BXB3
Organism: Mus musculus/domesticus
Length: 706  
Fragment?: true
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Publication
25859222 | J:237754
 
First Author: Maga AM
Year: 2015
Journal: Front Physiol
Title: Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.
Volume: 6
Pages: 92
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Protein
P70414
Organism: Mus musculus/domesticus
Length: 970  
Fragment?: false
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Protein
Q68FL0
Organism: Mus musculus/domesticus
Length: 958  
Fragment?: false
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Protein
Q27PY9
Organism: Mus musculus/domesticus
Length: 664  
Fragment?: false
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Protein
A0A3Q4L326
Organism: Mus musculus/domesticus
Length: 599  
Fragment?: true
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Protein
A0A3Q4EBU5
Organism: Mus musculus/domesticus
Length: 940  
Fragment?: false
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Protein
Q9ET74
Organism: Mus musculus/domesticus
Length: 600  
Fragment?: true
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Protein
O35157
Organism: Mus musculus/domesticus
Length: 940  
Fragment?: false
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Protein
G5E8Y0
Organism: Mus musculus/domesticus
Length: 970  
Fragment?: false
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Protein
Q91ZJ7
Organism: Mus musculus/domesticus
Length: 600  
Fragment?: true
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Protein
G3X9J1
Organism: Mus musculus/domesticus
Length: 970  
Fragment?: false
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Protein
Q3ULT5
Organism: Mus musculus/domesticus
Length: 924  
Fragment?: true
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Protein
Q3UNP2
Organism: Mus musculus/domesticus
Length: 893  
Fragment?: false
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Publication
28705898 | J:243411
First Author: Rutledge EA
Year: 2017
Journal: Development
Title: Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Volume: 144
Issue: 17
Pages: 3177-3188
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Publication
26930384 | J:231595
First Author: Gurdziel K
Year: 2016
Journal: Dev Dyn
Title: Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.
Volume: 245
Issue: 5
Pages: 614-26
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Protein
Q8VHN7
Organism: Mus musculus/domesticus
Length: 6298  
Fragment?: false
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Protein
B8JJE0
Organism: Mus musculus/domesticus
Length: 6298  
Fragment?: false
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Protein
A2A863
Organism: Mus musculus/domesticus
Length: 1818  
Fragment?: false
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Protein
A2A864
Organism: Mus musculus/domesticus
Length: 1802  
Fragment?: false
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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